ZA867063B - Substituted bridged-diazabicycloalkyl quinolone carboxylic acids - Google Patents

Substituted bridged-diazabicycloalkyl quinolone carboxylic acids

Info

Publication number
ZA867063B
ZA867063B ZA867063A ZA867063A ZA867063B ZA 867063 B ZA867063 B ZA 867063B ZA 867063 A ZA867063 A ZA 867063A ZA 867063 A ZA867063 A ZA 867063A ZA 867063 B ZA867063 B ZA 867063B
Authority
ZA
South Africa
Prior art keywords
carboxylic acids
quinolone carboxylic
substituted bridged
diazabicycloalkyl
alkyl
Prior art date
Application number
ZA867063A
Other languages
English (en)
Inventor
Martin Raymond Jefson
Paul Robert Mcguirk
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA867063B publication Critical patent/ZA867063B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Materials For Photolithography (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
ZA867063A 1985-09-18 1986-09-17 Substituted bridged-diazabicycloalkyl quinolone carboxylic acids ZA867063B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77747185A 1985-09-18 1985-09-18

Publications (1)

Publication Number Publication Date
ZA867063B true ZA867063B (en) 1988-04-27

Family

ID=25110350

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA867063A ZA867063B (en) 1985-09-18 1986-09-17 Substituted bridged-diazabicycloalkyl quinolone carboxylic acids

Country Status (42)

Country Link
US (3) US4861779A (fr)
EP (1) EP0215650B1 (fr)
JP (1) JPH0798819B2 (fr)
KR (1) KR870000961B1 (fr)
CN (1) CN1014789B (fr)
AT (1) ATE72245T1 (fr)
AU (1) AU576302B2 (fr)
BG (2) BG49275A3 (fr)
CA (1) CA1340734C (fr)
CY (1) CY1774A (fr)
CZ (1) CZ277825B6 (fr)
DD (1) DD259190A5 (fr)
DE (2) DE19675019I2 (fr)
DK (1) DK171276B1 (fr)
EG (1) EG18184A (fr)
ES (1) ES2001428A6 (fr)
FI (1) FI87565C (fr)
GR (1) GR862363B (fr)
HK (1) HK132795A (fr)
HU (1) HU200462B (fr)
IE (1) IE58966B1 (fr)
IL (1) IL80033A (fr)
IN (1) IN166416B (fr)
LU (1) LU90356I2 (fr)
MA (1) MA20770A1 (fr)
MW (1) MW5886A1 (fr)
MX (1) MX173358B (fr)
MY (1) MY102518A (fr)
NO (1) NO170335C (fr)
NZ (1) NZ217614A (fr)
OA (1) OA08410A (fr)
PH (2) PH24048A (fr)
PL (1) PL149987B1 (fr)
PT (1) PT83388B (fr)
SG (1) SG28094G (fr)
SK (1) SK667886A3 (fr)
SU (1) SU1482531A3 (fr)
UA (1) UA6340A1 (fr)
YU (1) YU45024B (fr)
ZA (1) ZA867063B (fr)
ZM (1) ZM8586A1 (fr)
ZW (1) ZW19386A1 (fr)

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WO1990002123A1 (fr) * 1988-08-23 1990-03-08 Pfizer Inc. Acides et esters carboxyliques de quinolones azabicycliques a structure en pont et a substitution amino
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US5929086A (en) * 1996-05-10 1999-07-27 Pharmacia & Upjohn Company Topical administration of antimicrobial agents for the treatment of systemic bacterial diseases
US6056436A (en) * 1997-02-20 2000-05-02 University Of Maryland Simultaneous measurement of temperature and strain using optical sensors
CN1210277C (zh) * 1999-05-04 2005-07-13 神经研究公司 杂芳基二氮杂双环烷烃及其制备方法和应用
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FR2809731B1 (fr) * 2000-05-31 2002-07-19 Sanofi Synthelabo Derives de 1,4-diazabicyclo-[3.2.2] nonane-pheylisoxazole, leur preparation et leur application en therapeutique
WO2002070522A1 (fr) * 2001-03-02 2002-09-12 Neurosearch A/S Nouveaux derives de 2,5-diazabicyclo[2.2.1]heptane
BR0314201A (pt) * 2002-09-10 2005-07-12 Pfizer Prod Inc Compostos diazabicìclicos úteis no tratamento de doenças do cns e outros distúrbios
US7429664B2 (en) * 2002-09-25 2008-09-30 Memory Pharmaceuticals Corporation Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof
DE10312346A1 (de) * 2003-03-20 2004-09-30 Bayer Healthcare Ag Kontrolliertes Freisetzungssystem
DE10351448A1 (de) 2003-11-04 2005-06-09 Bayer Healthcare Ag Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften
EP1697378B1 (fr) 2003-12-22 2007-11-21 Memory Pharmaceuticals Corporation Indoles, 1h-indazoles, 1,2-benzisoxazoles, et 1,2-benzisothiazoles, et leur preparation et utilisation
CA2560741C (fr) 2004-03-25 2013-08-06 Memory Pharmaceuticals Corporation Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, et leur preparation et leurs utilisations
ATE487716T1 (de) * 2004-04-22 2010-11-15 Memory Pharm Corp Indole, 1h-indazole, 1,2-benzisoxazole, 1,2- benzoisothiazole, deren herstellung und verwendungen
US7632831B2 (en) * 2004-05-07 2009-12-15 Memory Pharmaceuticals Corporation 1H-indazoles, benzothiazoles, 1,2-benzoisoxazoles, 1,2-benzoisothiazoles, and chromones and preparation and uses thereof
DE102005055385A1 (de) * 2004-12-09 2006-06-14 Bayer Healthcare Ag Arzneimittel zur hygienischen Applikation im Ohr
KR20070087674A (ko) 2004-12-22 2007-08-28 메모리 파마슈티칼스 코포레이션 니코틴 α-7 수용체 리간드 및 이의 제조 및 용도
US8106066B2 (en) 2005-09-23 2012-01-31 Memory Pharmaceuticals Corporation Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof
JP2009526024A (ja) 2006-02-10 2009-07-16 ノイロサーチ アクティーゼルスカブ ニコチン性アセチルコリン受容体アゴニストとしての3−ヘテロアリール−3,9−ジアザビシクロ[3.3.1]ノナン誘導体
CN101379063A (zh) 2006-02-10 2009-03-04 神经研究公司 3,9-二氮杂双环[3.3.1]壬烷衍生物及其作为单胺神经递质再摄取抑制剂的用途
CA2641683A1 (fr) 2006-02-10 2007-08-16 Neurosearch A/S Derives de 3,9-diazabicyclo [3.3.1]nonane et leur utilisation en tant qu'inhibiteurs de reabsorption de neurotransmetteur de monoamine
DE102006010643A1 (de) 2006-03-08 2007-09-13 Bayer Healthcare Aktiengesellschaft Arzneimittel enthaltend Fluorchinolone
DE102006010642A1 (de) * 2006-03-08 2007-09-27 Bayer Healthcare Aktiengesellschaft Arzneimittelformulierungen, enthaltend Fluorchinolone
DE102007026550A1 (de) * 2007-06-08 2008-12-11 Bayer Healthcare Ag Extrudate mit verbesserter Geschmacksmaskierung
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WO2009111680A1 (fr) * 2008-03-07 2009-09-11 Smithline Beecham Corporation Antagonistes de trpv4
EP2406266B1 (fr) * 2009-03-11 2013-12-25 Kyorin Pharmaceutical Co., Ltd. 7-cycloalkylaminoquinolones comme inhibiteurs de la gsk-3
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DE3766299D1 (de) * 1986-07-04 1991-01-03 Chemie Linz Gmbh 4-chinolon-3-carbonsaeurederivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
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Also Published As

Publication number Publication date
MX3751A (es) 1993-09-01
ATE72245T1 (de) 1992-02-15
CZ667886A3 (en) 1993-02-17
PL261410A1 (en) 1987-11-16
IL80033A0 (en) 1986-12-31
US5091383A (en) 1992-02-25
DE3683711D1 (de) 1992-03-12
NO863718L (no) 1987-03-19
MA20770A1 (fr) 1987-04-01
NO170335C (no) 1992-10-07
IE58966B1 (en) 1993-12-01
PL149987B1 (en) 1990-04-30
NO863718D0 (no) 1986-09-17
YU45024B (en) 1991-06-30
PH24048A (en) 1990-03-05
IL80033A (en) 1992-05-25
CN86106385A (zh) 1987-06-03
ZW19386A1 (en) 1986-12-10
YU161786A (en) 1987-10-31
EP0215650B1 (fr) 1992-01-29
GR862363B (en) 1987-01-19
FI87565B (fi) 1992-10-15
US4861779A (en) 1989-08-29
IN166416B (fr) 1990-05-05
HUT43070A (en) 1987-09-28
DK445886D0 (da) 1986-09-17
SU1482531A3 (ru) 1989-05-23
OA08410A (fr) 1988-06-30
LU90356I2 (fr) 1999-04-26
BG61091B2 (bg) 1996-10-31
FI863756A0 (fi) 1986-09-17
SK278605B6 (en) 1997-11-05
IE862479L (en) 1987-03-18
CY1774A (en) 1995-10-20
ES2001428A6 (es) 1988-05-16
HU200462B (en) 1990-06-28
KR870003106A (ko) 1987-04-15
FI863756A (fi) 1987-03-19
AU6276886A (en) 1987-03-19
JPH0798819B2 (ja) 1995-10-25
DD259190A5 (de) 1988-08-17
DE19675019I2 (de) 2004-01-29
KR870000961B1 (ko) 1987-05-14
FI87565C (fi) 1993-01-25
CZ277825B6 (en) 1993-06-16
UA6340A1 (uk) 1994-12-29
MY102518A (en) 1992-07-31
PT83388A (en) 1986-10-01
EP0215650A3 (en) 1987-12-02
BG49275A3 (en) 1991-09-16
HK132795A (en) 1995-09-01
SK667886A3 (en) 1997-11-05
AU576302B2 (en) 1988-08-18
NZ217614A (en) 1989-11-28
PH25338A (en) 1991-04-30
US4775668A (en) 1988-10-04
DK171276B1 (da) 1996-08-19
NO170335B (no) 1992-06-29
CN1014789B (zh) 1991-11-20
PT83388B (pt) 1989-05-12
ZM8586A1 (en) 1987-03-27
EP0215650A2 (fr) 1987-03-25
EG18184A (en) 1992-12-30
SG28094G (en) 1994-10-28
DK445886A (da) 1987-05-27
MX173358B (es) 1994-02-23
MW5886A1 (en) 1987-12-09
CA1340734C (fr) 1999-09-14
JPS62103083A (ja) 1987-05-13

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