OA08410A - Nouveaux acides quinolone-carboxyliques substitués à substituant diazabicycloalkyle ponté. - Google Patents

Nouveaux acides quinolone-carboxyliques substitués à substituant diazabicycloalkyle ponté.

Info

Publication number
OA08410A
OA08410A OA58953A OA58953A OA08410A OA 08410 A OA08410 A OA 08410A OA 58953 A OA58953 A OA 58953A OA 58953 A OA58953 A OA 58953A OA 08410 A OA08410 A OA 08410A
Authority
OA
OAPI
Prior art keywords
carboxylic acids
new substituted
bridged
substituted quinolone
substituent
Prior art date
Application number
OA58953A
Other languages
English (en)
Inventor
Martin Raymond Jefson
Paul Robert Mcguirk
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of OA08410A publication Critical patent/OA08410A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Materials For Photolithography (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
OA58953A 1985-09-18 1986-09-17 Nouveaux acides quinolone-carboxyliques substitués à substituant diazabicycloalkyle ponté. OA08410A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77747185A 1985-09-18 1985-09-18

Publications (1)

Publication Number Publication Date
OA08410A true OA08410A (fr) 1988-06-30

Family

ID=25110350

Family Applications (1)

Application Number Title Priority Date Filing Date
OA58953A OA08410A (fr) 1985-09-18 1986-09-17 Nouveaux acides quinolone-carboxyliques substitués à substituant diazabicycloalkyle ponté.

Country Status (42)

Country Link
US (3) US4861779A (fr)
EP (1) EP0215650B1 (fr)
JP (1) JPH0798819B2 (fr)
KR (1) KR870000961B1 (fr)
CN (1) CN1014789B (fr)
AT (1) ATE72245T1 (fr)
AU (1) AU576302B2 (fr)
BG (2) BG49275A3 (fr)
CA (1) CA1340734C (fr)
CY (1) CY1774A (fr)
CZ (1) CZ277825B6 (fr)
DD (1) DD259190A5 (fr)
DE (2) DE19675019I2 (fr)
DK (1) DK171276B1 (fr)
EG (1) EG18184A (fr)
ES (1) ES2001428A6 (fr)
FI (1) FI87565C (fr)
GR (1) GR862363B (fr)
HK (1) HK132795A (fr)
HU (1) HU200462B (fr)
IE (1) IE58966B1 (fr)
IL (1) IL80033A (fr)
IN (1) IN166416B (fr)
LU (1) LU90356I2 (fr)
MA (1) MA20770A1 (fr)
MW (1) MW5886A1 (fr)
MX (1) MX173358B (fr)
MY (1) MY102518A (fr)
NO (1) NO170335C (fr)
NZ (1) NZ217614A (fr)
OA (1) OA08410A (fr)
PH (2) PH24048A (fr)
PL (1) PL149987B1 (fr)
PT (1) PT83388B (fr)
SG (1) SG28094G (fr)
SK (1) SK667886A3 (fr)
SU (1) SU1482531A3 (fr)
UA (1) UA6340A1 (fr)
YU (1) YU45024B (fr)
ZA (1) ZA867063B (fr)
ZM (1) ZM8586A1 (fr)
ZW (1) ZW19386A1 (fr)

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DE3601567A1 (de) * 1986-01-21 1987-07-23 Bayer Ag 7-(azabicycloalkyl)-chinoloncarbonsaeure- und -naphthyridon-carbonsaeure-derivate
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US4965273A (en) * 1986-10-08 1990-10-23 Bristol-Myers Company Certain 1-tertiary-butyl-naphthyridone carboxylic acid derivatives anti-bacterial agents
WO1989000158A1 (fr) * 1987-07-02 1989-01-12 Pfizer Inc. Acides et esters carboxyliques de quinolone de diazabicycloalkyle shunte
US4923879A (en) * 1987-07-31 1990-05-08 Warner-Lambert Company 1,8-Naphthyridines and their use as antibacterial agents
US4968799A (en) * 1987-07-31 1990-11-06 Warner-Lambert Company Antibacterial agents
US4992546A (en) * 1987-07-31 1991-02-12 Warner-Lambert Company Process for preparing 6,8-diazabicyclo[3.2.2]nonane derivatives
US4933335A (en) * 1987-08-07 1990-06-12 Warner-Lambert Company Quinolones as antibacterial agents
WO1989005643A1 (fr) * 1987-12-18 1989-06-29 Pfizer Inc. Acides carboxyliques de quinoline a substitution heterocyclique
DE3902079A1 (de) * 1988-04-15 1989-10-26 Bayer Ag I.m. injektionsformen von gyrase-inhibitoren
WO1990002123A1 (fr) * 1988-08-23 1990-03-08 Pfizer Inc. Acides et esters carboxyliques de quinolones azabicycliques a structure en pont et a substitution amino
US5147873A (en) * 1988-08-23 1992-09-15 Pfizer Inc. Amino-substituted bridged azabicyclic quinolone carboxylic acids and esters
US4895943A (en) * 1988-10-25 1990-01-23 Pfizer Inc. Preparation of 1,4-diazabicyclo(3.2.2)nonane
US5036153A (en) * 1989-05-11 1991-07-30 Braish Tamim F Preparation of 2,5-diazabicyclo[2.2.1]heptanes and intermediates
US5214051A (en) * 1989-08-01 1993-05-25 Pfizer Inc. Thiazolyl and oxazolyl[5,4-c]piperidyl-substituted quinolone-carboxylic acid and related analogs thereof having antibacterial properties are disclosed
US5157125A (en) * 1989-09-25 1992-10-20 Pfizer Inc. Optically active 2-alkyl-2,5-diazabicyclo[2.2.1]heptanes
US5013839A (en) * 1989-09-25 1991-05-07 Pfizer Inc. Process for optically active 2-alkyl-2,5-diazabicyclo(2.2.1) heptanes
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US5385913A (en) * 1989-10-06 1995-01-31 Pfizer Inc. 1,4-dihydro-4-oxo-3-quinoline derivatives as selectively toxic mammalian antibacterial agents
WO1991004972A1 (fr) * 1989-10-06 1991-04-18 Pfizer Inc. Derives de 1,4-dihydro-4-oxo-3-quinoline utilises comme agents antibacteriens mammiferes selectivement toxiques
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US5235054A (en) * 1992-07-15 1993-08-10 Pfizer Inc. 3-carboxaldehyde substituted quinolines and naphthyridines
GB2291421A (en) * 1994-07-16 1996-01-24 Pfizer A process for preparing a quinoline carboxylic acid
ES2092963B1 (es) * 1995-04-12 1997-12-16 Sint Quimica Sa Procedimiento para la preparacion del acido 1-ciclopropil-6-fluoro-1, 4-dihidro-7-(1s,4s)-5-metil-2,5-diazabiciclo(2.2.1) hept-2-il)-4-oxo-3-quinolincarboxilico y sus sales.
US5929086A (en) 1996-05-10 1999-07-27 Pharmacia & Upjohn Company Topical administration of antimicrobial agents for the treatment of systemic bacterial diseases
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CN1210277C (zh) 1999-05-04 2005-07-13 神经研究公司 杂芳基二氮杂双环烷烃及其制备方法和应用
FR2809730B1 (fr) * 2000-05-31 2002-07-19 Sanofi Synthelabo Derives de 1,4-diazabicyclo[3.2.2] nonanebenzoxazole, -benzothiazole et -benzimidazole, leur preparation et leur application therapeutique
FR2809731B1 (fr) * 2000-05-31 2002-07-19 Sanofi Synthelabo Derives de 1,4-diazabicyclo-[3.2.2] nonane-pheylisoxazole, leur preparation et leur application en therapeutique
FR2809732B1 (fr) * 2000-05-31 2002-07-19 Sanofi Synthelabo DERIVES DE 4(-2-PHENYLTHIAZOL-5-yl)-1,4-DIAZABICYCLO-[3.2.2] NONANE, LEUR PREPARATION ET LEUR APPLICATION ENTHERAPEUTIQUE
AU2002233181B2 (en) * 2001-03-02 2007-06-07 Neurosearch A/S Novel, 2,5-diazabicyclo[2.2.1]heptane derivatives
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JP4890762B2 (ja) 2002-09-25 2012-03-07 メモリー・ファーマシューティカルズ・コーポレイション インダゾール、ベンゾチアゾール、及びベンゾイソチアゾール、並びにそれらの調製及び使用
DE10312346A1 (de) * 2003-03-20 2004-09-30 Bayer Healthcare Ag Kontrolliertes Freisetzungssystem
DE10351448A1 (de) 2003-11-04 2005-06-09 Bayer Healthcare Ag Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften
DE602004010299T2 (de) 2003-12-22 2008-09-18 Memory Pharmaceuticals Corp. Indole, 1h-indazole, 1,2-benzisoxazole und 1,2-benzisothiazole und deren herstellung und anwendungen
CN103724343A (zh) * 2004-03-25 2014-04-16 记忆药物公司 吲唑、苯并噻唑、苯并异噻唑、苯并异噁唑及其制备和用途
WO2006001894A1 (fr) * 2004-04-22 2006-01-05 Memory Pharmaceutical Corporation Indoles, 1h-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, leur preparation et leurs utilisations
BRPI0510212A (pt) * 2004-05-07 2007-10-16 Memory Pharm Corp 1h-indazóis, benzotiazóis, 1,2 - benzoisoxazóis, 1,2-benzoisotiazóis, e cromonas e a preparação e usos dos mesmos
DE102005055385A1 (de) * 2004-12-09 2006-06-14 Bayer Healthcare Ag Arzneimittel zur hygienischen Applikation im Ohr
MX2007007328A (es) 2004-12-22 2007-07-25 Memory Pharm Corp Ligandos del receptor alfa-7 nicotinico y preparacion y sus usos.
US8106066B2 (en) * 2005-09-23 2012-01-31 Memory Pharmaceuticals Corporation Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof
CA2641685A1 (fr) 2006-02-10 2007-08-16 Neurosearch A/S Derives de 3-heteroaryl-3,9-diazabicyclo[3.3.1]nonane utilises en tant qu'agonistes du recepteur nicotinique de l'acetylcholine
WO2007090886A1 (fr) * 2006-02-10 2007-08-16 Neurosearch A/S Derives de 3,9-diazabicyclo[3.3.1]nonane et leur utilisation en tant qu'inhibiteurs du recaptage de neurotransmetteur monoamine
CA2641683A1 (fr) 2006-02-10 2007-08-16 Neurosearch A/S Derives de 3,9-diazabicyclo [3.3.1]nonane et leur utilisation en tant qu'inhibiteurs de reabsorption de neurotransmetteur de monoamine
DE102006010643A1 (de) 2006-03-08 2007-09-13 Bayer Healthcare Aktiengesellschaft Arzneimittel enthaltend Fluorchinolone
DE102006010642A1 (de) * 2006-03-08 2007-09-27 Bayer Healthcare Aktiengesellschaft Arzneimittelformulierungen, enthaltend Fluorchinolone
DE102007026550A1 (de) * 2007-06-08 2008-12-11 Bayer Healthcare Ag Extrudate mit verbesserter Geschmacksmaskierung
DE102007055341A1 (de) * 2007-11-19 2009-05-20 Bayer Animal Health Gmbh Stabilisierung öliger Suspensionen enthaltend hydrophobe Kieselsäuren
WO2009111680A1 (fr) * 2008-03-07 2009-09-11 Smithline Beecham Corporation Antagonistes de trpv4
MX2011009414A (es) * 2009-03-11 2011-10-19 Kyorin Seiyaku Kk 7-cicloalquiloaminoquinolonas como inhibidores de gsk-3.
CN103200930A (zh) 2010-10-12 2013-07-10 拜耳知识产权有限责任公司 非淀粉基软咀嚼品
KR102253847B1 (ko) 2012-12-19 2021-05-21 바이엘 애니멀 헬스 게엠베하 향상된 수용성 및 우수한 저장 안정성을 가지는 정제
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Also Published As

Publication number Publication date
YU161786A (en) 1987-10-31
FI863756A0 (fi) 1986-09-17
EP0215650A2 (fr) 1987-03-25
NO863718L (no) 1987-03-19
PH24048A (en) 1990-03-05
JPH0798819B2 (ja) 1995-10-25
LU90356I2 (fr) 1999-04-26
IE862479L (en) 1987-03-18
HU200462B (en) 1990-06-28
KR870003106A (ko) 1987-04-15
CZ277825B6 (en) 1993-06-16
ATE72245T1 (de) 1992-02-15
IN166416B (fr) 1990-05-05
DK445886D0 (da) 1986-09-17
DE3683711D1 (de) 1992-03-12
CZ667886A3 (en) 1993-02-17
BG61091B2 (bg) 1996-10-31
YU45024B (en) 1991-06-30
MX3751A (es) 1993-09-01
PL149987B1 (en) 1990-04-30
FI87565C (fi) 1993-01-25
ZW19386A1 (en) 1986-12-10
PL261410A1 (en) 1987-11-16
CN1014789B (zh) 1991-11-20
MX173358B (es) 1994-02-23
US4775668A (en) 1988-10-04
JPS62103083A (ja) 1987-05-13
IL80033A0 (en) 1986-12-31
DK445886A (da) 1987-05-27
PT83388B (pt) 1989-05-12
IL80033A (en) 1992-05-25
PT83388A (en) 1986-10-01
ZA867063B (en) 1988-04-27
DD259190A5 (de) 1988-08-17
HK132795A (en) 1995-09-01
IE58966B1 (en) 1993-12-01
MY102518A (en) 1992-07-31
CA1340734C (fr) 1999-09-14
FI863756A (fi) 1987-03-19
EP0215650A3 (en) 1987-12-02
EG18184A (en) 1992-12-30
MA20770A1 (fr) 1987-04-01
NO170335B (no) 1992-06-29
SK278605B6 (en) 1997-11-05
SU1482531A3 (ru) 1989-05-23
ZM8586A1 (en) 1987-03-27
CY1774A (en) 1995-10-20
SG28094G (en) 1994-10-28
NZ217614A (en) 1989-11-28
BG49275A3 (en) 1991-09-16
NO170335C (no) 1992-10-07
AU576302B2 (en) 1988-08-18
NO863718D0 (no) 1986-09-17
FI87565B (fi) 1992-10-15
UA6340A1 (uk) 1994-12-29
KR870000961B1 (ko) 1987-05-14
AU6276886A (en) 1987-03-19
PH25338A (en) 1991-04-30
DK171276B1 (da) 1996-08-19
MW5886A1 (en) 1987-12-09
EP0215650B1 (fr) 1992-01-29
GR862363B (en) 1987-01-19
DE19675019I2 (de) 2004-01-29
SK667886A3 (en) 1997-11-05
US5091383A (en) 1992-02-25
US4861779A (en) 1989-08-29
CN86106385A (zh) 1987-06-03
HUT43070A (en) 1987-09-28
ES2001428A6 (es) 1988-05-16

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