ZA861432B - Novel peptides - Google Patents

Novel peptides

Info

Publication number
ZA861432B
ZA861432B ZA861432A ZA861432A ZA861432B ZA 861432 B ZA861432 B ZA 861432B ZA 861432 A ZA861432 A ZA 861432A ZA 861432 A ZA861432 A ZA 861432A ZA 861432 B ZA861432 B ZA 861432B
Authority
ZA
South Africa
Prior art keywords
insulin
charge
amino acid
neutral
novel peptides
Prior art date
Application number
ZA861432A
Other languages
English (en)
Inventor
Jan Markussen
Original Assignee
Novo Industri As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri As filed Critical Novo Industri As
Publication of ZA861432B publication Critical patent/ZA861432B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA861432A 1985-03-12 1986-02-26 Novel peptides ZA861432B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK113585A DK113585D0 (da) 1985-03-12 1985-03-12 Nye peptider

Publications (1)

Publication Number Publication Date
ZA861432B true ZA861432B (en) 1986-11-26

Family

ID=8101410

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA861432A ZA861432B (en) 1985-03-12 1986-02-26 Novel peptides

Country Status (22)

Country Link
EP (1) EP0194864B1 (no)
JP (1) JPS61212598A (no)
KR (1) KR930007433B1 (no)
CN (1) CN86101489A (no)
AT (1) ATE77391T1 (no)
AU (1) AU612964B2 (no)
CS (1) CS259536B2 (no)
DD (1) DD244345A5 (no)
DE (1) DE3685668T2 (no)
DK (2) DK113585D0 (no)
ES (1) ES8800276A1 (no)
FI (1) FI861007A (no)
GR (1) GR860687B (no)
HU (1) HU201097B (no)
IL (1) IL78103A0 (no)
MY (1) MY102102A (no)
NO (1) NO172441C (no)
NZ (1) NZ215445A (no)
PH (1) PH24260A (no)
PT (1) PT82173B (no)
YU (1) YU46001B (no)
ZA (1) ZA861432B (no)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK347086D0 (da) * 1986-07-21 1986-07-21 Novo Industri As Novel peptides
US5008241A (en) * 1985-03-12 1991-04-16 Novo Nordisk A/S Novel insulin peptides
DK119785D0 (da) * 1985-03-15 1985-03-15 Nordisk Gentofte Insulinpraeparat
DK437786D0 (da) * 1986-09-12 1986-09-12 Nordisk Gentofte Insulinprecursorer
US5149777A (en) * 1988-07-20 1992-09-22 Novo Nordisk A/S Human insulin analogs and preparations containing them
DE3827533A1 (de) * 1988-08-13 1990-02-15 Hoechst Ag Pharmazeutische zubereitung zur behandlung des diabetes mellitus
DE3837825A1 (de) * 1988-11-08 1990-05-10 Hoechst Ag Neue insulinderivate, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
DK134189D0 (da) * 1989-03-20 1989-03-20 Nordisk Gentofte Insulinforbindelser
US5130298A (en) * 1989-05-16 1992-07-14 Ethicon, Inc. Stabilized compositions containing epidermal growth factor
DE3936876A1 (de) * 1989-11-06 1991-05-23 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
US6933272B1 (en) 1998-09-22 2005-08-23 Erik Helmerhorst Use of non-peptidyl compounds for the treatment of insulin related ailments
AUPP609198A0 (en) * 1998-09-22 1998-10-15 Curtin University Of Technology Use of non-peptidyl compounds for the treatment of insulin related ailments
DE10114178A1 (de) 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
DE10227232A1 (de) 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Saure Insulinzubereitungen mit verbesserter Stabilität
ES2642214T3 (es) 2004-01-21 2017-11-15 Novo Nordisk Health Care Ag Conjugación de péptidos mediante transglutaminasa
EP1969004B1 (en) 2005-12-28 2011-08-10 Novo Nordisk A/S Compositions comprising an acylated insulin and zinc and method of making the said compositions
DE102006031955A1 (de) * 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Insulinanaloga mit dibasischem B-Kettenende
DE102006031962A1 (de) * 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Amidiertes Insulin Glargin
DE102008003566A1 (de) * 2008-01-09 2009-07-16 Sanofi-Aventis Deutschland Gmbh Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
AU2009203810B2 (en) * 2008-01-09 2013-07-25 Sanofi-Aventis Deutschland Gmbh Novel insulin derivatives having an extremely delayed time-action profile
RU2524423C2 (ru) * 2008-01-09 2014-07-27 Санофи-Авентис Дойчланд Гмбх Новые производные инсулина с чрезвычайно замедленным профилем время/действие
CA2740685C (en) 2008-10-17 2018-09-11 Sanofi-Aventis Deutschland Gmbh Combination of an insulin and a glp-1 agonist
TW201105346A (en) * 2009-07-06 2011-02-16 Sanofi Aventis Deutschland Heat-stable and vibration-stable insulin preparations
AU2010317995B2 (en) 2009-11-13 2014-04-17 Sanofi-Aventis Deutschland Gmbh Pharmaceutical composition comprising a GLP-1 agonist, an insulin, and methionine
JP5973918B2 (ja) 2009-11-13 2016-08-23 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Ｇｌｐ−１アゴニスト及びメチオニンを含む薬学的組成物
US20130143803A1 (en) * 2010-05-10 2013-06-06 Novo Nordisk A/S Process for the Preparation of Insulin-Zinc Complexes
JP6199186B2 (ja) 2010-08-30 2017-09-20 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング ２型糖尿病の治療用の医薬の製造のためのａｖｅ００１０の使用
CN102174495A (zh) * 2011-01-20 2011-09-07 马忠仁 一种提取糜胰蛋白酶的方法
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
RU2650616C2 (ru) 2011-08-29 2018-04-16 Санофи-Авентис Дойчланд Гмбх Фармацевтическая комбинация для применения при гликемическом контроле у пациентов с сахарным диабетом 2 типа
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
HRP20230470T1 (hr) 2014-12-12 2023-07-21 Sanofi-Aventis Deutschland Gmbh Formulacija fiksnog omjera inzulin glargin/liksisenatid
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK319780A (da) * 1980-07-24 1982-01-25 Forenede Bryggerier As Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
DE3326472A1 (de) * 1983-07-22 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DE3333640A1 (de) * 1983-09-17 1985-04-25 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von insulin-derivaten, deren b-kette c-terminal verlaengert ist, neue basisch modifizierte insulin-derivate diese enthaltende mittel und ihre verwendung
DK119785D0 (da) * 1985-03-15 1985-03-15 Nordisk Gentofte Insulinpraeparat

Also Published As

Publication number Publication date
PT82173A (en) 1986-04-01
PH24260A (en) 1990-05-04
AU5449586A (en) 1986-09-18
DK158677B (da) 1990-07-02
DE3685668T2 (de) 1993-01-14
DD244345A5 (de) 1987-04-01
JPS61212598A (ja) 1986-09-20
DK107086A (da) 1986-11-07
MY102102A (en) 1992-03-31
PT82173B (pt) 1988-07-29
YU46001B (sh) 1992-12-21
YU34586A (en) 1988-10-31
GR860687B (en) 1986-07-11
NO172441B (no) 1993-04-13
CS166686A2 (en) 1987-12-17
NZ215445A (en) 1989-07-27
HU201097B (en) 1990-09-28
ES8800276A1 (es) 1987-11-01
IL78103A0 (en) 1986-07-31
KR930007433B1 (ko) 1993-08-10
NO172441C (no) 1993-07-21
CN86101489A (zh) 1987-01-21
EP0194864A2 (en) 1986-09-17
KR860007288A (ko) 1986-10-10
DK113585D0 (da) 1985-03-12
NO860920L (no) 1986-09-15
DK107086D0 (da) 1986-03-10
EP0194864A3 (en) 1989-01-11
FI861007A0 (fi) 1986-03-11
DE3685668D1 (en) 1992-07-23
DK158677C (da) 1990-12-31
ATE77391T1 (de) 1992-07-15
HUT41052A (en) 1987-03-30
ES552879A0 (es) 1987-11-01
FI861007A (fi) 1986-09-13
AU612964B2 (en) 1991-07-25
CS259536B2 (en) 1988-10-14
EP0194864B1 (en) 1992-06-17

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