ZA838462B - 6-hydroxy-lower alkylpenem compounds,processes for their manufacture,pharmaceutical preparations that contain these compounds,and the use of the latter - Google Patents
6-hydroxy-lower alkylpenem compounds,processes for their manufacture,pharmaceutical preparations that contain these compounds,and the use of the latterInfo
- Publication number
- ZA838462B ZA838462B ZA838462A ZA838462A ZA838462B ZA 838462 B ZA838462 B ZA 838462B ZA 838462 A ZA838462 A ZA 838462A ZA 838462 A ZA838462 A ZA 838462A ZA 838462 B ZA838462 B ZA 838462B
- Authority
- ZA
- South Africa
- Prior art keywords
- lower alkyl
- hydroxy
- carboxy
- radical
- formula
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 14
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 16
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 11
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 10
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 6
- 150000003839 salts Chemical class 0.000 abstract 5
- 125000003545 alkoxy group Chemical group 0.000 abstract 4
- 125000003282 alkyl amino group Chemical group 0.000 abstract 4
- 125000000524 functional group Chemical group 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 150000002367 halogens Chemical class 0.000 abstract 4
- -1 lower alkalnoylamino Chemical group 0.000 abstract 4
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 4
- 230000003287 optical effect Effects 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 3
- 125000004423 acyloxy group Chemical group 0.000 abstract 2
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
- 125000004414 alkyl thio group Chemical group 0.000 abstract 2
- 125000005237 alkyleneamino group Chemical group 0.000 abstract 2
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000002950 monocyclic group Chemical group 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000000369 oxido group Chemical group [*]=O 0.000 abstract 2
- 125000004043 oxo group Chemical group O=* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000003356 phenylsulfanyl group Chemical group [*]SC1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 2
- 230000004962 physiological condition Effects 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- PXQLVRUNWNTZOS-UHFFFAOYSA-N sulfanyl Chemical class [SH] PXQLVRUNWNTZOS-UHFFFAOYSA-N 0.000 abstract 2
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 125000005236 alkanoylamino group Chemical group 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000002894 organic compounds Chemical class 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000001476 phosphono group Chemical group [H]OP(*)(=O)O[H] 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 239000011574 phosphorus Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C265/00—Derivatives of isocyanic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/568—Four-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Indole Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH667082 | 1982-11-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA838462B true ZA838462B (en) | 1984-06-27 |
Family
ID=4313181
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA838462A ZA838462B (en) | 1982-11-16 | 1983-11-14 | 6-hydroxy-lower alkylpenem compounds,processes for their manufacture,pharmaceutical preparations that contain these compounds,and the use of the latter |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0110826B1 (fi) |
JP (1) | JPS59101492A (fi) |
KR (1) | KR840006665A (fi) |
AT (1) | ATE29031T1 (fi) |
AU (1) | AU569264B2 (fi) |
DD (1) | DD215551A5 (fi) |
DE (1) | DE3373098D1 (fi) |
DK (1) | DK522783A (fi) |
ES (2) | ES8605525A1 (fi) |
FI (1) | FI76348C (fi) |
GR (1) | GR79072B (fi) |
HU (1) | HU192827B (fi) |
IE (1) | IE56236B1 (fi) |
IL (1) | IL70232A (fi) |
NO (1) | NO834189L (fi) |
NZ (1) | NZ206278A (fi) |
PH (1) | PH21930A (fi) |
PT (1) | PT77658B (fi) |
ZA (1) | ZA838462B (fi) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4794109A (en) * | 1982-11-16 | 1988-12-27 | Ciba-Geigy Corporation | 6-hydroxy-lower alkylpenem compounds, pharmaceutical preparations that contain these compounds, and the use of the latter |
EP0148128A3 (de) * | 1983-12-30 | 1985-08-07 | Ciba-Geigy Ag | Neue optisch aktive Penem-Verbindungen |
GB8416651D0 (en) * | 1984-06-29 | 1984-08-01 | Erba Farmitalia | Penem derivatives |
US4617300A (en) * | 1984-09-21 | 1986-10-14 | Schering Corporation | 2(N-heterocyclyl) penems |
GB8509180D0 (en) * | 1985-04-10 | 1985-05-15 | Erba Farmitalia | Penem derivatives |
US4891369A (en) * | 1986-12-03 | 1990-01-02 | Taiho Pharmaceutical Company, Limited | 2β-Substituted-methylpenicillanic acid derivatives, and salts and esters thereof |
EP0275233A1 (de) * | 1987-01-14 | 1988-07-20 | Ciba-Geigy Ag | 2-Heterocyclylalkyl-2-penem-Verbindungen |
IT1262908B (it) * | 1992-09-17 | 1996-07-22 | Menarini Farma Ind | Derivati penems; loro preparazione e composizioni farmacologiche che li contengono |
DE102014117978A1 (de) | 2013-12-06 | 2015-06-11 | Werth Messtechnik Gmbh | Vorrichtung und Verfahren zur Messung von Werkstücken |
DE102015121582A1 (de) | 2014-12-12 | 2016-06-16 | Werth Messtechnik Gmbh | Verfahren und Vorrichtung zur Messung von Merkmalen an Werkstücken |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4168314A (en) * | 1977-11-17 | 1979-09-18 | Merck & Co., Inc. | 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid |
EP0003960B1 (de) * | 1978-02-02 | 1983-06-29 | Ciba-Geigy Ag | 6-Substituierte Thia-Azaverbindungen, ihre Herstellung und diese enthaltende pharmazeutische Präparate |
JPS5625110A (en) * | 1978-12-18 | 1981-03-10 | Bristol Myers Co | Antibacterial |
IT1193922B (it) * | 1979-02-24 | 1988-08-31 | Erba Farmitalia | Agenti antibatterici ed inibitori di beta -lattamasi e loro preparazione |
EP0109362A1 (de) * | 1982-11-16 | 1984-05-23 | Ciba-Geigy Ag | Heterocyclylverbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate, welche diese Verbindungen enthalten, und Verwendung von letzteren |
EP0125207A1 (de) * | 1983-05-06 | 1984-11-14 | Ciba-Geigy Ag | 2-Tetrazolylpropyl-2-penem-Verbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate, welche diese Verbindungen enthalten, und Verwendung von letzteren |
-
1983
- 1983-11-08 PH PH29799A patent/PH21930A/en unknown
- 1983-11-10 EP EP83810519A patent/EP0110826B1/de not_active Expired
- 1983-11-10 DE DE8383810519T patent/DE3373098D1/de not_active Expired
- 1983-11-10 AT AT83810519T patent/ATE29031T1/de not_active IP Right Cessation
- 1983-11-11 FI FI834139A patent/FI76348C/fi not_active IP Right Cessation
- 1983-11-14 ZA ZA838462A patent/ZA838462B/xx unknown
- 1983-11-14 DD DD83256670A patent/DD215551A5/de unknown
- 1983-11-14 IL IL70232A patent/IL70232A/xx unknown
- 1983-11-14 JP JP58212651A patent/JPS59101492A/ja active Pending
- 1983-11-14 PT PT77658A patent/PT77658B/pt unknown
- 1983-11-15 ES ES527292A patent/ES8605525A1/es not_active Expired
- 1983-11-15 DK DK522783A patent/DK522783A/da not_active Application Discontinuation
- 1983-11-15 HU HU833928A patent/HU192827B/hu unknown
- 1983-11-15 IE IE2673/83A patent/IE56236B1/xx unknown
- 1983-11-15 KR KR1019830005448A patent/KR840006665A/ko not_active Application Discontinuation
- 1983-11-15 NO NO834189A patent/NO834189L/no unknown
- 1983-11-15 NZ NZ206278A patent/NZ206278A/en unknown
- 1983-11-15 GR GR72989A patent/GR79072B/el unknown
- 1983-11-15 AU AU21388/83A patent/AU569264B2/en not_active Expired - Fee Related
-
1985
- 1985-05-28 ES ES543556A patent/ES8609335A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
IE832673L (en) | 1984-05-16 |
AU569264B2 (en) | 1988-01-28 |
EP0110826A1 (de) | 1984-06-13 |
HU192827B (en) | 1987-07-28 |
FI834139A (fi) | 1984-05-17 |
IL70232A0 (en) | 1984-02-29 |
NO834189L (no) | 1984-05-18 |
ES543556A0 (es) | 1986-09-01 |
ES527292A0 (es) | 1986-03-16 |
DK522783D0 (da) | 1983-11-15 |
JPS59101492A (ja) | 1984-06-12 |
DK522783A (da) | 1984-05-17 |
FI76348B (fi) | 1988-06-30 |
DE3373098D1 (en) | 1987-09-24 |
IE56236B1 (en) | 1991-05-22 |
PH21930A (en) | 1988-04-08 |
FI76348C (fi) | 1988-10-10 |
ES8609335A1 (es) | 1986-09-01 |
EP0110826B1 (de) | 1987-08-19 |
IL70232A (en) | 1988-03-31 |
DD215551A5 (de) | 1984-11-14 |
GR79072B (fi) | 1984-10-02 |
ES8605525A1 (es) | 1986-03-16 |
NZ206278A (en) | 1986-05-09 |
KR840006665A (ko) | 1984-12-01 |
ATE29031T1 (de) | 1987-09-15 |
PT77658B (en) | 1986-05-12 |
AU2138883A (en) | 1984-05-24 |
PT77658A (en) | 1983-12-01 |
FI834139A0 (fi) | 1983-11-11 |
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