IL70232A - 6-(hydroxy-lower alkyl)-penem compounds,their manufacture and pharmaceutical compositions containing them - Google Patents

6-(hydroxy-lower alkyl)-penem compounds,their manufacture and pharmaceutical compositions containing them

Info

Publication number
IL70232A
IL70232A IL70232A IL7023283A IL70232A IL 70232 A IL70232 A IL 70232A IL 70232 A IL70232 A IL 70232A IL 7023283 A IL7023283 A IL 7023283A IL 70232 A IL70232 A IL 70232A
Authority
IL
Israel
Prior art keywords
lower alkyl
hydroxy
carboxy
radical
formula
Prior art date
Application number
IL70232A
Other languages
English (en)
Other versions
IL70232A0 (en
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of IL70232A0 publication Critical patent/IL70232A0/xx
Publication of IL70232A publication Critical patent/IL70232A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C265/00—Derivatives of isocyanic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568—Four-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL70232A 1982-11-16 1983-11-14 6-(hydroxy-lower alkyl)-penem compounds,their manufacture and pharmaceutical compositions containing them IL70232A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH667082 1982-11-16

Publications (2)

Publication Number Publication Date
IL70232A0 IL70232A0 (en) 1984-02-29
IL70232A true IL70232A (en) 1988-03-31

Family

ID=4313181

Family Applications (1)

Application Number Title Priority Date Filing Date
IL70232A IL70232A (en) 1982-11-16 1983-11-14 6-(hydroxy-lower alkyl)-penem compounds,their manufacture and pharmaceutical compositions containing them

Country Status (19)

Country Link
EP (1) EP0110826B1 (fi)
JP (1) JPS59101492A (fi)
KR (1) KR840006665A (fi)
AT (1) ATE29031T1 (fi)
AU (1) AU569264B2 (fi)
DD (1) DD215551A5 (fi)
DE (1) DE3373098D1 (fi)
DK (1) DK522783A (fi)
ES (2) ES8605525A1 (fi)
FI (1) FI76348C (fi)
GR (1) GR79072B (fi)
HU (1) HU192827B (fi)
IE (1) IE56236B1 (fi)
IL (1) IL70232A (fi)
NO (1) NO834189L (fi)
NZ (1) NZ206278A (fi)
PH (1) PH21930A (fi)
PT (1) PT77658B (fi)
ZA (1) ZA838462B (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4794109A (en) * 1982-11-16 1988-12-27 Ciba-Geigy Corporation 6-hydroxy-lower alkylpenem compounds, pharmaceutical preparations that contain these compounds, and the use of the latter
DK613984A (da) * 1983-12-30 1985-07-01 Ciba Geigy Ag 2-heterocyclyl-6-hydroxylavalkyl-2-penem-forbindelser samt deres fremstilling og anvendelse
GB8416651D0 (en) * 1984-06-29 1984-08-01 Erba Farmitalia Penem derivatives
US4617300A (en) * 1984-09-21 1986-10-14 Schering Corporation 2(N-heterocyclyl) penems
GB8509180D0 (en) * 1985-04-10 1985-05-15 Erba Farmitalia Penem derivatives
US4891369A (en) * 1986-12-03 1990-01-02 Taiho Pharmaceutical Company, Limited 2β-Substituted-methylpenicillanic acid derivatives, and salts and esters thereof
EP0275233A1 (de) * 1987-01-14 1988-07-20 Ciba-Geigy Ag 2-Heterocyclylalkyl-2-penem-Verbindungen
IT1262908B (it) * 1992-09-17 1996-07-22 Menarini Farma Ind Derivati penems; loro preparazione e composizioni farmacologiche che li contengono
DE102014117978A1 (de) 2013-12-06 2015-06-11 Werth Messtechnik Gmbh Vorrichtung und Verfahren zur Messung von Werkstücken
DE102015121582A1 (de) 2014-12-12 2016-06-16 Werth Messtechnik Gmbh Verfahren und Vorrichtung zur Messung von Merkmalen an Werkstücken

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
EP0003960B1 (de) * 1978-02-02 1983-06-29 Ciba-Geigy Ag 6-Substituierte Thia-Azaverbindungen, ihre Herstellung und diese enthaltende pharmazeutische Präparate
JPS5625110A (en) * 1978-12-18 1981-03-10 Bristol Myers Co Antibacterial
NL192265C (nl) * 1979-02-24 1997-04-03 Erba Carlo Spa Penemcarbonzuur-verbindingen en farmaceutische preparaten die deze verbindingen bevatten.
EP0109362A1 (de) * 1982-11-16 1984-05-23 Ciba-Geigy Ag Heterocyclylverbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate, welche diese Verbindungen enthalten, und Verwendung von letzteren
EP0125207A1 (de) * 1983-05-06 1984-11-14 Ciba-Geigy Ag 2-Tetrazolylpropyl-2-penem-Verbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate, welche diese Verbindungen enthalten, und Verwendung von letzteren

Also Published As

Publication number Publication date
AU2138883A (en) 1984-05-24
ZA838462B (en) 1984-06-27
NO834189L (no) 1984-05-18
ES527292A0 (es) 1986-03-16
AU569264B2 (en) 1988-01-28
GR79072B (fi) 1984-10-02
DE3373098D1 (en) 1987-09-24
NZ206278A (en) 1986-05-09
ES543556A0 (es) 1986-09-01
EP0110826B1 (de) 1987-08-19
DK522783A (da) 1984-05-17
KR840006665A (ko) 1984-12-01
DD215551A5 (de) 1984-11-14
EP0110826A1 (de) 1984-06-13
FI76348C (fi) 1988-10-10
HU192827B (en) 1987-07-28
IL70232A0 (en) 1984-02-29
FI834139L (fi) 1984-05-17
ES8605525A1 (es) 1986-03-16
PT77658B (en) 1986-05-12
IE832673L (en) 1984-05-16
PT77658A (en) 1983-12-01
JPS59101492A (ja) 1984-06-12
DK522783D0 (da) 1983-11-15
ES8609335A1 (es) 1986-09-01
FI834139A0 (fi) 1983-11-11
IE56236B1 (en) 1991-05-22
PH21930A (en) 1988-04-08
ATE29031T1 (de) 1987-09-15
FI76348B (fi) 1988-06-30

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