ZA835799B - Substituted 9-(1-o-or 3-o-monosubstituted or 1,3-d1-o-substituted propoxymethyl)-purines as antiviral agents - Google Patents

Substituted 9-(1-o-or 3-o-monosubstituted or 1,3-d1-o-substituted propoxymethyl)-purines as antiviral agents

Info

Publication number
ZA835799B
ZA835799B ZA835799A ZA835799A ZA835799B ZA 835799 B ZA835799 B ZA 835799B ZA 835799 A ZA835799 A ZA 835799A ZA 835799 A ZA835799 A ZA 835799A ZA 835799 B ZA835799 B ZA 835799B
Authority
ZA
South Africa
Prior art keywords
sup
carbon atoms
substituted
hydrogen
antiviral agents
Prior art date
Application number
ZA835799A
Other languages
English (en)
Inventor
Julien Pierre Henri Verheyden
Martin John Charles
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of ZA835799B publication Critical patent/ZA835799B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/17—Unsaturated ethers containing halogen
    • C07C43/174—Unsaturated ethers containing halogen containing six-membered aromatic rings
    • C07C43/1745—Unsaturated ethers containing halogen containing six-membered aromatic rings having more than one ether bound
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
    • C07C43/1785—Unsaturated ethers containing hydroxy or O-metal groups having more than one ether bound
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oncology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA835799A 1982-08-09 1983-08-08 Substituted 9-(1-o-or 3-o-monosubstituted or 1,3-d1-o-substituted propoxymethyl)-purines as antiviral agents ZA835799B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/406,583 US4556659A (en) 1982-08-09 1982-08-09 Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-Di-0-substituted propoxymethyl)-purines as antiviral agents

Publications (1)

Publication Number Publication Date
ZA835799B true ZA835799B (en) 1984-04-25

Family

ID=23608623

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA835799A ZA835799B (en) 1982-08-09 1983-08-08 Substituted 9-(1-o-or 3-o-monosubstituted or 1,3-d1-o-substituted propoxymethyl)-purines as antiviral agents

Country Status (15)

Country Link
US (1) US4556659A (fi)
EP (1) EP0105135B1 (fi)
JP (1) JPS5948483A (fi)
KR (1) KR890000811B1 (fi)
AT (1) ATE25980T1 (fi)
AU (1) AU571451B2 (fi)
DE (1) DE3370331D1 (fi)
DK (1) DK361383A (fi)
ES (2) ES524811A0 (fi)
FI (1) FI74006C (fi)
HU (1) HU193530B (fi)
IE (1) IE55843B1 (fi)
NO (1) NO162469C (fi)
NZ (1) NZ205171A (fi)
ZA (1) ZA835799B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816447A (en) * 1981-08-26 1989-03-28 Merck & Co., Inc. Anti-viral guanine compounds
US4609661A (en) * 1982-08-09 1986-09-02 Syntex (U.S.A.) Inc. Substituted 9-(1-O- or 3-O-monosubstituted or 1,3-di-O-substituted propoxymethyl)purines as antiviral agents
ATE33653T1 (de) * 1982-10-14 1988-05-15 Wellcome Found Antivirale purinderivate.
US4880820A (en) * 1983-06-24 1989-11-14 Merck & Co., Inc. Guanine derivatives
US4897479A (en) * 1983-09-30 1990-01-30 Merck & Co., Inc. Arylsulfonyloxy purine intermediates
SE8406538D0 (sv) * 1984-12-21 1984-12-21 Astra Laekemedel Ab Novel derivatives of purine
US4642346A (en) * 1985-06-24 1987-02-10 Syntex (U.S.A.) Inc. Anhydrous crystalline 9-(1,3-dihydroxy-2-propoxymethyl)guanine
GB8904855D0 (en) * 1989-03-03 1989-04-12 Beecham Group Plc Pharmaceutical treatment
DE4002792A1 (de) * 1990-01-31 1991-08-01 Teves Gmbh Alfred Vorrichtung zur ermittlung der beschaffenheit einer druckuebertragungsfluessigkeit
GB2260319B (en) 1991-10-07 1995-12-06 Norsk Hydro As Acyl derivatives of nucleosides and nucleoside analogues having anti-viral activity
CN110026212B (zh) * 2019-05-23 2022-03-04 临海市利民化工有限公司 一种裂解催化剂及使用该催化剂制备西他沙星中间体的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4199574A (en) * 1974-09-02 1980-04-22 Burroughs Wellcome Co. Methods and compositions for treating viral infections and guanine acyclic nucleosides
AT380252B (de) * 1981-08-11 1986-05-12 Wellcome Found Verfahren zur herstellung von neuen guanin- und 2,6-diaminopurinderivaten und ihren salzen
NZ201662A (en) * 1981-08-26 1986-07-11 Merck & Co Inc 9-(1,3-(and 2,3)-dihydroxy-1-(and 2)-propoxy-methyl)guanine derivatives and methods for their preparation

Also Published As

Publication number Publication date
DE3370331D1 (en) 1987-04-23
AU1768383A (en) 1984-02-16
ES8603185A1 (es) 1986-01-01
NZ205171A (en) 1987-05-29
FI74006B (fi) 1987-08-31
EP0105135A1 (en) 1984-04-11
KR840006007A (ko) 1984-11-21
EP0105135B1 (en) 1987-03-18
ES545261A0 (es) 1986-01-01
HU193530B (en) 1987-10-28
NO832842L (no) 1984-02-10
KR890000811B1 (ko) 1989-04-08
JPS5948483A (ja) 1984-03-19
AU571451B2 (en) 1988-04-21
FI832832A (fi) 1984-02-10
DK361383D0 (da) 1983-08-08
FI74006C (fi) 1987-12-10
NO162469B (no) 1989-09-25
FI832832A0 (fi) 1983-08-08
DK361383A (da) 1984-02-10
IE831867L (en) 1984-02-09
ES524811A0 (es) 1986-01-01
NO162469C (no) 1990-01-10
ATE25980T1 (de) 1987-04-15
IE55843B1 (en) 1991-01-30
US4556659A (en) 1985-12-03
ES8603186A1 (es) 1986-01-01

Similar Documents

Publication Publication Date Title
ES8504194A1 (es) Procedimiento para preparar 9-(1 o 3-monoaciloxi-o 1,3-diaciloxi-2-propoximetil)-purinas substituidas en calidad de agentes antiviricos.
ZA835799B (en) Substituted 9-(1-o-or 3-o-monosubstituted or 1,3-d1-o-substituted propoxymethyl)-purines as antiviral agents
ZA83328B (en) 5,6,7-trinor-4,8-itner-m-phenylene prostaglandin i2 derivative
ES2000346A6 (es) Un procedimiento para la preparacion de derivados de distamicina
GB2124077B (en) Immunomodulating agent
ES472738A1 (es) Procedimiento para la obtencion de alfa-halometil derivados de aminas
ES451602A1 (es) Un procedimiento para la preparacion de una composicion de- tergente liquida.
ES483854A1 (es) Proceso para la obtencion de un derivado de 2-deoxi-5-fluo- rouridina.
ES478508A1 (es) Procedimiento para la preparacion de derivados alfa-acetile-nicos de alfa-animo acidos.
ES8506979A1 (es) Procedimiento para preparar nuevas sales de alquil (cadena larga) amonio de n-fosfonometilglicina
ES451235A1 (es) Un procedimiento para la preparacion de una composicion de- tergente.
ATE50773T1 (de) Alkylresorcinolphosphite.
ES2104177T3 (es) Analogos noveles de la vitamina d.
ES8203916A1 (es) Procedimiento para preparar n6-adenosina
ES8306378A1 (es) "un procedimiento para la preparacion de derivados de adenosina".
TW198034B (fi)
AU1450288A (en) Sulfonyldecahydro-8h-isoquino-(2,1-g) (1,6)-naphthyridines, optical isomers thereof and related compounds
ES8301931A1 (es) Un procedimiento para la preparacion de nuevos imidazoles.
ES8203917A1 (es) Un procedimiento para la preparacion de un derivado de nu- cleosido de adenina
ZA825576B (en) Benzodioxane-imidazoline compounds as antihypertensives
IL74269A0 (en) 2-alkoxyaminosulfonylbenzene-sulfonylureas,their production and their use as herbicides
DE2963942D1 (en) N-(1,2-azolyl)alkyl-chloroacetanilides, process for their preparation and their use as herbicides
ES467744A1 (es) Un procedimiento para preparar un fungicida que contiene sa-les organicas de amonio cuaternario
US4206146A (en) 2-Decarboxy-2-aminomethyl-trans-2,3-didehydro-9-deoxy-9-methylene-PGF compounds
ATE16797T1 (de) 1-(3,4-bis-(3-(alkoxycarbonyl)-2-thioureido)phenyl-1-phenylethylen.