DK361383A - Substituerede 9-(1-0- eller 3-0-monosubstituerede eller 1,3-dl-o-substituerede propoxymethyl)-puriner og fremgangsmaade til fremstilling deraf - Google Patents

Substituerede 9-(1-0- eller 3-0-monosubstituerede eller 1,3-dl-o-substituerede propoxymethyl)-puriner og fremgangsmaade til fremstilling deraf Download PDF

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Publication number
DK361383A
DK361383A DK361383A DK361383A DK361383A DK 361383 A DK361383 A DK 361383A DK 361383 A DK361383 A DK 361383A DK 361383 A DK361383 A DK 361383A DK 361383 A DK361383 A DK 361383A
Authority
DK
Denmark
Prior art keywords
sup
substituted
carbon atoms
hydrogen
defined above
Prior art date
Application number
DK361383A
Other languages
Danish (da)
English (en)
Other versions
DK361383D0 (da
Inventor
Julien Pierre Henri Verheyden
John Charles Martin
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of DK361383D0 publication Critical patent/DK361383D0/da
Publication of DK361383A publication Critical patent/DK361383A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/17—Unsaturated ethers containing halogen
    • C07C43/174—Unsaturated ethers containing halogen containing six-membered aromatic rings
    • C07C43/1745—Unsaturated ethers containing halogen containing six-membered aromatic rings having more than one ether bound
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
    • C07C43/1785—Unsaturated ethers containing hydroxy or O-metal groups having more than one ether bound
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK361383A 1982-08-09 1983-08-08 Substituerede 9-(1-0- eller 3-0-monosubstituerede eller 1,3-dl-o-substituerede propoxymethyl)-puriner og fremgangsmaade til fremstilling deraf DK361383A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/406,583 US4556659A (en) 1982-08-09 1982-08-09 Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-Di-0-substituted propoxymethyl)-purines as antiviral agents

Publications (2)

Publication Number Publication Date
DK361383D0 DK361383D0 (da) 1983-08-08
DK361383A true DK361383A (da) 1984-02-10

Family

ID=23608623

Family Applications (1)

Application Number Title Priority Date Filing Date
DK361383A DK361383A (da) 1982-08-09 1983-08-08 Substituerede 9-(1-0- eller 3-0-monosubstituerede eller 1,3-dl-o-substituerede propoxymethyl)-puriner og fremgangsmaade til fremstilling deraf

Country Status (15)

Country Link
US (1) US4556659A (fi)
EP (1) EP0105135B1 (fi)
JP (1) JPS5948483A (fi)
KR (1) KR890000811B1 (fi)
AT (1) ATE25980T1 (fi)
AU (1) AU571451B2 (fi)
DE (1) DE3370331D1 (fi)
DK (1) DK361383A (fi)
ES (2) ES524811A0 (fi)
FI (1) FI74006C (fi)
HU (1) HU193530B (fi)
IE (1) IE55843B1 (fi)
NO (1) NO162469C (fi)
NZ (1) NZ205171A (fi)
ZA (1) ZA835799B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816447A (en) * 1981-08-26 1989-03-28 Merck & Co., Inc. Anti-viral guanine compounds
US4609661A (en) * 1982-08-09 1986-09-02 Syntex (U.S.A.) Inc. Substituted 9-(1-O- or 3-O-monosubstituted or 1,3-di-O-substituted propoxymethyl)purines as antiviral agents
ATE33654T1 (de) * 1982-10-14 1988-05-15 Wellcome Found Antivirale purinderivate.
US4880820A (en) * 1983-06-24 1989-11-14 Merck & Co., Inc. Guanine derivatives
US4897479A (en) * 1983-09-30 1990-01-30 Merck & Co., Inc. Arylsulfonyloxy purine intermediates
SE8406538D0 (sv) * 1984-12-21 1984-12-21 Astra Laekemedel Ab Novel derivatives of purine
US4642346A (en) * 1985-06-24 1987-02-10 Syntex (U.S.A.) Inc. Anhydrous crystalline 9-(1,3-dihydroxy-2-propoxymethyl)guanine
GB8904855D0 (en) * 1989-03-03 1989-04-12 Beecham Group Plc Pharmaceutical treatment
DE4002792A1 (de) * 1990-01-31 1991-08-01 Teves Gmbh Alfred Vorrichtung zur ermittlung der beschaffenheit einer druckuebertragungsfluessigkeit
GB2260319B (en) * 1991-10-07 1995-12-06 Norsk Hydro As Acyl derivatives of nucleosides and nucleoside analogues having anti-viral activity
CN110026212B (zh) * 2019-05-23 2022-03-04 临海市利民化工有限公司 一种裂解催化剂及使用该催化剂制备西他沙星中间体的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4199574A (en) * 1974-09-02 1980-04-22 Burroughs Wellcome Co. Methods and compositions for treating viral infections and guanine acyclic nucleosides
AU569462B2 (en) * 1981-08-11 1988-02-04 Wellcome Foundation Limited, The Antiviral purine derivatives
NZ201662A (en) * 1981-08-26 1986-07-11 Merck & Co Inc 9-(1,3-(and 2,3)-dihydroxy-1-(and 2)-propoxy-methyl)guanine derivatives and methods for their preparation

Also Published As

Publication number Publication date
FI74006B (fi) 1987-08-31
ES8603185A1 (es) 1986-01-01
HU193530B (en) 1987-10-28
NO832842L (no) 1984-02-10
US4556659A (en) 1985-12-03
ES545261A0 (es) 1986-01-01
IE831867L (en) 1984-02-09
FI832832A0 (fi) 1983-08-08
FI74006C (fi) 1987-12-10
DE3370331D1 (en) 1987-04-23
EP0105135B1 (en) 1987-03-18
AU1768383A (en) 1984-02-16
JPS5948483A (ja) 1984-03-19
KR890000811B1 (ko) 1989-04-08
DK361383D0 (da) 1983-08-08
ATE25980T1 (de) 1987-04-15
NZ205171A (en) 1987-05-29
IE55843B1 (en) 1991-01-30
NO162469B (no) 1989-09-25
ES524811A0 (es) 1986-01-01
AU571451B2 (en) 1988-04-21
ZA835799B (en) 1984-04-25
EP0105135A1 (en) 1984-04-11
ES8603186A1 (es) 1986-01-01
NO162469C (no) 1990-01-10
FI832832A (fi) 1984-02-10
KR840006007A (ko) 1984-11-21

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