DE3370331D1 - Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-di-0-substituted 1,3 dihydroxy-2-propoxymethyl) purines as antiviral agents - Google Patents
Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-di-0-substituted 1,3 dihydroxy-2-propoxymethyl) purines as antiviral agentsInfo
- Publication number
- DE3370331D1 DE3370331D1 DE8383107818T DE3370331T DE3370331D1 DE 3370331 D1 DE3370331 D1 DE 3370331D1 DE 8383107818 T DE8383107818 T DE 8383107818T DE 3370331 T DE3370331 T DE 3370331T DE 3370331 D1 DE3370331 D1 DE 3370331D1
- Authority
- DE
- Germany
- Prior art keywords
- sup
- carbon atoms
- substituted
- hydrogen
- antiviral agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/17—Unsaturated ethers containing halogen
- C07C43/174—Unsaturated ethers containing halogen containing six-membered aromatic rings
- C07C43/1745—Unsaturated ethers containing halogen containing six-membered aromatic rings having more than one ether bound
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
- C07C43/1785—Unsaturated ethers containing hydroxy or O-metal groups having more than one ether bound
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/406,583 US4556659A (en) | 1982-08-09 | 1982-08-09 | Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-Di-0-substituted propoxymethyl)-purines as antiviral agents |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3370331D1 true DE3370331D1 (en) | 1987-04-23 |
Family
ID=23608623
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8383107818T Expired DE3370331D1 (en) | 1982-08-09 | 1983-08-08 | Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-di-0-substituted 1,3 dihydroxy-2-propoxymethyl) purines as antiviral agents |
Country Status (15)
Country | Link |
---|---|
US (1) | US4556659A (de) |
EP (1) | EP0105135B1 (de) |
JP (1) | JPS5948483A (de) |
KR (1) | KR890000811B1 (de) |
AT (1) | ATE25980T1 (de) |
AU (1) | AU571451B2 (de) |
DE (1) | DE3370331D1 (de) |
DK (1) | DK361383A (de) |
ES (2) | ES8603185A1 (de) |
FI (1) | FI74006C (de) |
HU (1) | HU193530B (de) |
IE (1) | IE55843B1 (de) |
NO (1) | NO162469C (de) |
NZ (1) | NZ205171A (de) |
ZA (1) | ZA835799B (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816447A (en) * | 1981-08-26 | 1989-03-28 | Merck & Co., Inc. | Anti-viral guanine compounds |
US4609661A (en) * | 1982-08-09 | 1986-09-02 | Syntex (U.S.A.) Inc. | Substituted 9-(1-O- or 3-O-monosubstituted or 1,3-di-O-substituted propoxymethyl)purines as antiviral agents |
JPS5989682A (ja) * | 1982-10-14 | 1984-05-23 | ザ・ウエルカム・フアウンデ−シヨン | プリン誘導体 |
US4880820A (en) * | 1983-06-24 | 1989-11-14 | Merck & Co., Inc. | Guanine derivatives |
US4897479A (en) * | 1983-09-30 | 1990-01-30 | Merck & Co., Inc. | Arylsulfonyloxy purine intermediates |
SE8406538D0 (sv) * | 1984-12-21 | 1984-12-21 | Astra Laekemedel Ab | Novel derivatives of purine |
US4642346A (en) * | 1985-06-24 | 1987-02-10 | Syntex (U.S.A.) Inc. | Anhydrous crystalline 9-(1,3-dihydroxy-2-propoxymethyl)guanine |
GB8904855D0 (en) * | 1989-03-03 | 1989-04-12 | Beecham Group Plc | Pharmaceutical treatment |
DE4002792A1 (de) * | 1990-01-31 | 1991-08-01 | Teves Gmbh Alfred | Vorrichtung zur ermittlung der beschaffenheit einer druckuebertragungsfluessigkeit |
GB2260319B (en) * | 1991-10-07 | 1995-12-06 | Norsk Hydro As | Acyl derivatives of nucleosides and nucleoside analogues having anti-viral activity |
CN110026212B (zh) * | 2019-05-23 | 2022-03-04 | 临海市利民化工有限公司 | 一种裂解催化剂及使用该催化剂制备西他沙星中间体的方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4199574A (en) * | 1974-09-02 | 1980-04-22 | Burroughs Wellcome Co. | Methods and compositions for treating viral infections and guanine acyclic nucleosides |
MC1475A1 (fr) * | 1981-08-11 | 1983-06-17 | Wellcome Found | Procede de preparation de derives de la purine a action anti-virale |
NZ201662A (en) * | 1981-08-26 | 1986-07-11 | Merck & Co Inc | 9-(1,3-(and 2,3)-dihydroxy-1-(and 2)-propoxy-methyl)guanine derivatives and methods for their preparation |
-
1982
- 1982-08-09 US US06/406,583 patent/US4556659A/en not_active Expired - Fee Related
-
1983
- 1983-08-08 AU AU17683/83A patent/AU571451B2/en not_active Ceased
- 1983-08-08 ES ES524811A patent/ES8603185A1/es not_active Expired
- 1983-08-08 ZA ZA835799A patent/ZA835799B/xx unknown
- 1983-08-08 FI FI832832A patent/FI74006C/fi not_active IP Right Cessation
- 1983-08-08 NZ NZ205171A patent/NZ205171A/en unknown
- 1983-08-08 NO NO832842A patent/NO162469C/no unknown
- 1983-08-08 KR KR1019830003708A patent/KR890000811B1/ko not_active IP Right Cessation
- 1983-08-08 DE DE8383107818T patent/DE3370331D1/de not_active Expired
- 1983-08-08 JP JP58144857A patent/JPS5948483A/ja active Pending
- 1983-08-08 DK DK361383A patent/DK361383A/da not_active Application Discontinuation
- 1983-08-08 IE IE1867/83A patent/IE55843B1/xx unknown
- 1983-08-08 HU HU832792A patent/HU193530B/hu not_active IP Right Cessation
- 1983-08-08 EP EP83107818A patent/EP0105135B1/de not_active Expired
- 1983-08-08 AT AT83107818T patent/ATE25980T1/de active
-
1985
- 1985-07-16 ES ES545261A patent/ES545261A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
DK361383D0 (da) | 1983-08-08 |
FI832832A0 (fi) | 1983-08-08 |
NO832842L (no) | 1984-02-10 |
IE55843B1 (en) | 1991-01-30 |
US4556659A (en) | 1985-12-03 |
ES524811A0 (es) | 1986-01-01 |
KR890000811B1 (ko) | 1989-04-08 |
ES8603185A1 (es) | 1986-01-01 |
FI74006C (fi) | 1987-12-10 |
AU571451B2 (en) | 1988-04-21 |
FI74006B (fi) | 1987-08-31 |
KR840006007A (ko) | 1984-11-21 |
NO162469C (no) | 1990-01-10 |
DK361383A (da) | 1984-02-10 |
JPS5948483A (ja) | 1984-03-19 |
AU1768383A (en) | 1984-02-16 |
EP0105135A1 (de) | 1984-04-11 |
HU193530B (en) | 1987-10-28 |
IE831867L (en) | 1984-02-09 |
ES8603186A1 (es) | 1986-01-01 |
NZ205171A (en) | 1987-05-29 |
FI832832A (fi) | 1984-02-10 |
ATE25980T1 (de) | 1987-04-15 |
NO162469B (no) | 1989-09-25 |
ZA835799B (en) | 1984-04-25 |
ES545261A0 (es) | 1986-01-01 |
EP0105135B1 (de) | 1987-03-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |