FI74006B - Foerfarande foer framstaellning av antivirala substituerade 9(1-0- eller 3-0-monosubstituerad- eller 1,3-di-0-substituerad propoximetyl)guaniiner. - Google Patents

Foerfarande foer framstaellning av antivirala substituerade 9(1-0- eller 3-0-monosubstituerad- eller 1,3-di-0-substituerad propoximetyl)guaniiner.

Info

Publication number
FI74006B
FI74006B FI832832A FI832832A FI74006B FI 74006 B FI74006 B FI 74006B FI 832832 A FI832832 A FI 832832A FI 832832 A FI832832 A FI 832832A FI 74006 B FI74006 B FI 74006B
Authority
FI
Finland
Prior art keywords
sup
carbon atoms
eller
substitutes
hydrogen
Prior art date
Application number
FI832832A
Other languages
English (en)
Other versions
FI832832A0 (fi
FI74006C (fi
FI832832A (fi
Inventor
Julien Pierre Henri Verheyden
John Charles Martin
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of FI832832A0 publication Critical patent/FI832832A0/fi
Publication of FI832832A publication Critical patent/FI832832A/fi
Application granted granted Critical
Publication of FI74006B publication Critical patent/FI74006B/fi
Publication of FI74006C publication Critical patent/FI74006C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/17—Unsaturated ethers containing halogen
    • C07C43/174—Unsaturated ethers containing halogen containing six-membered aromatic rings
    • C07C43/1745—Unsaturated ethers containing halogen containing six-membered aromatic rings having more than one ether bound
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
    • C07C43/1785—Unsaturated ethers containing hydroxy or O-metal groups having more than one ether bound
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oncology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI832832A 1982-08-09 1983-08-08 Foerfarande foer framstaellning av antivirala substituerade 9(1-0- eller 3-0-monosubstituerad- eller 1,3-di-0-substituerad propoximetyl)guaniiner. FI74006C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/406,583 US4556659A (en) 1982-08-09 1982-08-09 Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-Di-0-substituted propoxymethyl)-purines as antiviral agents
US40658382 1982-08-09

Publications (4)

Publication Number Publication Date
FI832832A0 FI832832A0 (fi) 1983-08-08
FI832832A FI832832A (fi) 1984-02-10
FI74006B true FI74006B (fi) 1987-08-31
FI74006C FI74006C (fi) 1987-12-10

Family

ID=23608623

Family Applications (1)

Application Number Title Priority Date Filing Date
FI832832A FI74006C (fi) 1982-08-09 1983-08-08 Foerfarande foer framstaellning av antivirala substituerade 9(1-0- eller 3-0-monosubstituerad- eller 1,3-di-0-substituerad propoximetyl)guaniiner.

Country Status (15)

Country Link
US (1) US4556659A (fi)
EP (1) EP0105135B1 (fi)
JP (1) JPS5948483A (fi)
KR (1) KR890000811B1 (fi)
AT (1) ATE25980T1 (fi)
AU (1) AU571451B2 (fi)
DE (1) DE3370331D1 (fi)
DK (1) DK361383A (fi)
ES (2) ES8603185A1 (fi)
FI (1) FI74006C (fi)
HU (1) HU193530B (fi)
IE (1) IE55843B1 (fi)
NO (1) NO162469C (fi)
NZ (1) NZ205171A (fi)
ZA (1) ZA835799B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816447A (en) * 1981-08-26 1989-03-28 Merck & Co., Inc. Anti-viral guanine compounds
US4609661A (en) * 1982-08-09 1986-09-02 Syntex (U.S.A.) Inc. Substituted 9-(1-O- or 3-O-monosubstituted or 1,3-di-O-substituted propoxymethyl)purines as antiviral agents
DE3376325D1 (en) * 1982-10-14 1988-05-26 Wellcome Found Antiviral purine derivatives
US4880820A (en) * 1983-06-24 1989-11-14 Merck & Co., Inc. Guanine derivatives
US4897479A (en) * 1983-09-30 1990-01-30 Merck & Co., Inc. Arylsulfonyloxy purine intermediates
SE8406538D0 (sv) * 1984-12-21 1984-12-21 Astra Laekemedel Ab Novel derivatives of purine
US4642346A (en) * 1985-06-24 1987-02-10 Syntex (U.S.A.) Inc. Anhydrous crystalline 9-(1,3-dihydroxy-2-propoxymethyl)guanine
GB8904855D0 (en) * 1989-03-03 1989-04-12 Beecham Group Plc Pharmaceutical treatment
DE4002792A1 (de) * 1990-01-31 1991-08-01 Teves Gmbh Alfred Vorrichtung zur ermittlung der beschaffenheit einer druckuebertragungsfluessigkeit
GB2260319B (en) 1991-10-07 1995-12-06 Norsk Hydro As Acyl derivatives of nucleosides and nucleoside analogues having anti-viral activity
CN110026212B (zh) * 2019-05-23 2022-03-04 临海市利民化工有限公司 一种裂解催化剂及使用该催化剂制备西他沙星中间体的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4199574A (en) * 1974-09-02 1980-04-22 Burroughs Wellcome Co. Methods and compositions for treating viral infections and guanine acyclic nucleosides
KR880002276B1 (ko) * 1981-08-11 1988-10-21 더 웰컴 화운데이션 리미티드 항비루스성 화합물의 제조방법
NZ201662A (en) * 1981-08-26 1986-07-11 Merck & Co Inc 9-(1,3-(and 2,3)-dihydroxy-1-(and 2)-propoxy-methyl)guanine derivatives and methods for their preparation

Also Published As

Publication number Publication date
HU193530B (en) 1987-10-28
AU571451B2 (en) 1988-04-21
ES8603186A1 (es) 1986-01-01
ES524811A0 (es) 1986-01-01
IE831867L (en) 1984-02-09
EP0105135B1 (en) 1987-03-18
FI832832A0 (fi) 1983-08-08
ES545261A0 (es) 1986-01-01
KR890000811B1 (ko) 1989-04-08
DE3370331D1 (en) 1987-04-23
NO832842L (no) 1984-02-10
US4556659A (en) 1985-12-03
ATE25980T1 (de) 1987-04-15
NO162469C (no) 1990-01-10
JPS5948483A (ja) 1984-03-19
IE55843B1 (en) 1991-01-30
FI74006C (fi) 1987-12-10
DK361383D0 (da) 1983-08-08
ZA835799B (en) 1984-04-25
NO162469B (no) 1989-09-25
AU1768383A (en) 1984-02-16
FI832832A (fi) 1984-02-10
ES8603185A1 (es) 1986-01-01
EP0105135A1 (en) 1984-04-11
KR840006007A (ko) 1984-11-21
DK361383A (da) 1984-02-10
NZ205171A (en) 1987-05-29

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: SYNTEX (U.S.A.) INC.