ZA708590B - Isoquinoline derivatives - Google Patents

Isoquinoline derivatives

Info

Publication number
ZA708590B
ZA708590B ZA708590A ZA708590A ZA708590B ZA 708590 B ZA708590 B ZA 708590B ZA 708590 A ZA708590 A ZA 708590A ZA 708590 A ZA708590 A ZA 708590A ZA 708590 B ZA708590 B ZA 708590B
Authority
ZA
South Africa
Prior art keywords
isoquinoline derivatives
isoquinoline
derivatives
Prior art date
Application number
ZA708590A
Other languages
English (en)
Inventor
A Rheiner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA708590B publication Critical patent/ZA708590B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA708590A 1970-01-06 1970-12-21 Isoquinoline derivatives ZA708590B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH10370A CH527194A (de) 1970-01-06 1970-01-06 Verfahren zur Herstellung von Isochinolin-Derivaten

Publications (1)

Publication Number Publication Date
ZA708590B true ZA708590B (en) 1971-09-29

Family

ID=4179328

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA708590A ZA708590B (en) 1970-01-06 1970-12-21 Isoquinoline derivatives

Country Status (19)

Country Link
JP (1) JPS5515476B1 (OSRAM)
AT (1) AT303041B (OSRAM)
BE (1) BE761219A (OSRAM)
CA (1) CA999866A (OSRAM)
CH (2) CH527194A (OSRAM)
DE (1) DE2062001C2 (OSRAM)
DK (1) DK125021B (OSRAM)
ES (1) ES387016A1 (OSRAM)
FI (1) FI49503C (OSRAM)
FR (1) FR2081412B1 (OSRAM)
GB (1) GB1335261A (OSRAM)
IE (1) IE34859B1 (OSRAM)
IL (1) IL35916A (OSRAM)
NL (1) NL171444C (OSRAM)
NO (1) NO135315C (OSRAM)
PH (1) PH9682A (OSRAM)
SE (3) SE368401B (OSRAM)
YU (1) YU33660B (OSRAM)
ZA (1) ZA708590B (OSRAM)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
MXPA02004330A (es) 1999-11-03 2004-07-30 Albany Molecular Res Inc Tetrahidroisoquinolinas aril-y heteroaril-sustituidas y uso de las mismas para bloquear la recaptacion de norepinefrina, dopamina y serotonina..
KR20080065707A (ko) * 1999-11-03 2008-07-14 에이엠알 테크놀로지, 인크. 4-페닐-치환 테트라히드로이소퀴놀린, 및 노르에피네프린과도파민과 세로토닌의 재흡수를 차단하기 위한 이의 용도
US7163949B1 (en) * 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
EP1113007A1 (en) 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
CN100430401C (zh) * 2000-07-11 2008-11-05 Amr科技公司 新的4-苯基取代的四氢异喹啉类化合物及其治疗用途
CN103880827B (zh) 2004-07-15 2017-01-04 阿尔巴尼分子研究公司 芳基和杂芳基取代的四氢异喹啉及其阻断去甲肾上腺素、多巴胺和血清素的重摄取的应用
JP2008543880A (ja) 2005-06-17 2008-12-04 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ナフチリジン化合物
UA95454C2 (uk) 2005-07-15 2011-08-10 Амр Текнолоджи, Інк. Арил- і гетероарилзаміщені тетрагідробензазепіни і їх застосування для блокування зворотного захоплення норепінефрину, допаміну і серотоніну
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
KR101830447B1 (ko) 2009-05-12 2018-02-20 알바니 몰레큘라 리써치, 인크. 7-(［1,2,4］트리아졸로［1,5-α］피리딘-6-일)-4-(3,4-디클로로페닐)-1,2,3,4-테트라하이드로이소퀴놀린 및 이의 용도
EP2429295B1 (en) 2009-05-12 2013-12-25 Albany Molecular Research, Inc. Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof
US8815894B2 (en) 2009-05-12 2014-08-26 Bristol-Myers Squibb Company Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline and use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen

Also Published As

Publication number Publication date
DE2062001A1 (de) 1971-07-15
NO135315C (OSRAM) 1977-03-23
NL7018956A (OSRAM) 1971-07-08
IE34859L (en) 1971-07-06
FR2081412B1 (OSRAM) 1974-04-12
FI49503C (fi) 1975-07-10
GB1335261A (en) 1973-10-24
DE2062001C2 (de) 1986-10-16
JPS5515476B1 (OSRAM) 1980-04-23
NO135315B (OSRAM) 1976-12-13
CH527194A (de) 1972-08-31
SE399879B (sv) 1978-03-06
AT303041B (de) 1972-11-10
SE368401B (OSRAM) 1974-07-01
BE761219A (fr) 1971-07-05
YU33660B (en) 1977-12-31
NL171444B (nl) 1982-11-01
IL35916A (en) 1973-11-28
NL171444C (nl) 1983-04-05
CA999866A (en) 1976-11-16
PH9682A (en) 1976-02-10
YU1971A (en) 1977-06-30
IL35916A0 (en) 1971-02-25
SE386672B (sv) 1976-08-16
CH538477A (de) 1973-06-30
IE34859B1 (en) 1975-09-03
FI49503B (OSRAM) 1975-04-01
FR2081412A1 (OSRAM) 1971-12-03
DK125021B (da) 1972-12-18
ES387016A1 (es) 1976-05-01

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