ZA201707783B - Antifungal compounds - Google Patents
Antifungal compoundsInfo
- Publication number
- ZA201707783B ZA201707783B ZA2017/07783A ZA201707783A ZA201707783B ZA 201707783 B ZA201707783 B ZA 201707783B ZA 2017/07783 A ZA2017/07783 A ZA 2017/07783A ZA 201707783 A ZA201707783 A ZA 201707783A ZA 201707783 B ZA201707783 B ZA 201707783B
- Authority
- ZA
- South Africa
- Prior art keywords
- antifungal compounds
- antifungal
- compounds
- Prior art date
Links
- 230000000843 anti-fungal effect Effects 0.000 title 1
- 229940121375 antifungal agent Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562163106P | 2015-05-18 | 2015-05-18 | |
| PCT/US2016/032877 WO2016187201A2 (en) | 2015-05-18 | 2016-05-17 | Antifungal compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201707783B true ZA201707783B (en) | 2019-06-26 |
Family
ID=57320616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2017/07783A ZA201707783B (en) | 2015-05-18 | 2017-11-16 | Antifungal compounds |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US11051514B2 (https=) |
| EP (2) | EP3297998B1 (https=) |
| JP (1) | JP6908533B2 (https=) |
| KR (1) | KR20180000731A (https=) |
| CN (1) | CN107750248A (https=) |
| AR (1) | AR104695A1 (https=) |
| AU (2) | AU2016265932B2 (https=) |
| BR (1) | BR112017024463B1 (https=) |
| CA (1) | CA2986041C (https=) |
| CL (1) | CL2017002929A1 (https=) |
| CO (1) | CO2017012621A2 (https=) |
| CR (1) | CR20170574A (https=) |
| DK (1) | DK3297998T3 (https=) |
| EA (1) | EA034387B1 (https=) |
| EC (1) | ECSP17082683A (https=) |
| ES (1) | ES2776241T3 (https=) |
| HK (2) | HK1253073A1 (https=) |
| IL (1) | IL255605B (https=) |
| LT (1) | LT3297998T (https=) |
| MX (1) | MX378499B (https=) |
| PH (1) | PH12017502082B1 (https=) |
| TW (1) | TWI623527B (https=) |
| UA (1) | UA120784C2 (https=) |
| WO (1) | WO2016187201A2 (https=) |
| ZA (1) | ZA201707783B (https=) |
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| JP6633539B2 (ja) * | 2014-03-19 | 2020-01-22 | ダウ アグロサイエンシィズ エルエルシー | 2−(2,4−ジフルオロフェニル)−1,1−ジフルオロ−1−(5−置換−ピリジン−2−イル)−3−(1h−テトラゾール−1−イル)プロパン−2−オールおよびその調製工程 |
| JP6572234B2 (ja) | 2014-03-19 | 2019-09-04 | ヴィアメット ファーマスーティカルズ(エヌシー),インコーポレイテッド | 抗真菌化合物の調製方法 |
| CA2942231A1 (en) | 2014-03-19 | 2015-09-24 | Viamet Pharmaceuticals, Inc. | Antifungal compound process |
| ES2800905T3 (es) | 2014-03-19 | 2021-01-05 | Mycovia Pharmaceuticals Inc | Procedimiento para compuesto antifúngico |
| AU2015231275B2 (en) | 2014-03-19 | 2019-03-07 | Mycovia Pharmaceuticals, Inc. | Antifungal compound process |
| BR112016021257B1 (pt) | 2014-03-19 | 2021-03-02 | Viamet Pharmaceuticals (NC), Inc. | 2-(2,4- difluorofenil-1,1-diflúor-1-(5-substituído-piridin-2-il)-3- (1h-tetrazol-1-il)propan-2-óis e processos para preparação e uso dos mesmos |
| AU2015231226B2 (en) | 2014-03-19 | 2019-04-04 | Mycovia Pharmaceuticals, Inc. | Antifungal compound process |
| CA2942936A1 (en) | 2014-03-19 | 2015-09-24 | Viamet Pharmaceuticals, Inc. | Antifungal compound process |
| CA2942972A1 (en) | 2014-03-19 | 2015-09-24 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Antifungal compound process |
| JP6687625B2 (ja) | 2014-12-30 | 2020-04-22 | ダウ アグロサイエンシィズ エルエルシー | 殺真菌活性を有するピコリンアミド化合物 |
| JP6847458B2 (ja) | 2015-09-18 | 2021-03-24 | マイコヴィア ファーマシューティカルズ,インコーポレイテッド | 抗真菌化合物のプロセス |
| US20180370946A1 (en) * | 2015-11-17 | 2018-12-27 | Dow Agrosciences Llc | 4-((6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile and processes of preparation |
| AR106729A1 (es) * | 2015-11-17 | 2018-02-14 | Viamet Pharmaceuticals Inc | 4-((6-(2-(2,4-difluorofenil)-1,1-difluoro-2-oxoetil)piridin-3-il)oxi)benzonitrilo y proceso para su preparación |
| TWI679198B (zh) | 2015-11-17 | 2019-12-11 | 美商陶氏益農有限責任公司 | 製備4-((6-(2-(2,4-二氟苯基)-1,1-二氟-2-羥基-3-(1h-1,2,4-三唑-1-基)丙基)吡啶-3-基)氧基)苄腈之方法 |
| KR20180100313A (ko) * | 2015-11-17 | 2018-09-10 | 다우 아그로사이언시즈 엘엘씨 | 4-((6-(2-(2,4-디플루오로페닐)-1,1-디플루오로-2-히드록시-3-(1h-1,2,4-트리아졸-1-일)프로필)피리딘-3-일)옥시)벤조니트릴 및 제조방법 |
| BR112019009759A2 (pt) * | 2016-11-18 | 2019-08-13 | Dow Agrosciences Llc | 4-((6-(2-(2,4-difluorofenil)-1,1-difluoro-2-hidróxi-3-(5-mercapto-1h-1,2,4-triazol-1-il)propil)piridin-3-il)óxi)benzonitrila e processos de preparação |
| CN109963841A (zh) * | 2016-11-18 | 2019-07-02 | 美国陶氏益农公司 | 4-((6-(2-(2,4-二氟苯基)-1,1-二氟-2-羟基-3-(5-巯基-1h-1,2,4-三唑-1-基)丙基)吡啶-3-基)氧基)苄腈及制备方法 |
| CN110023296A (zh) * | 2016-11-18 | 2019-07-16 | 美国陶氏益农公司 | 4-((6-(2-(2,4-二氟苯基)-1,1-二氟-2-羟基-3-(5-巯基-1h-1,2,4-三唑-1-基)丙基)吡啶-3-基)氧基)苄腈及制备方法 |
| BR112019009767A2 (pt) * | 2016-11-18 | 2019-08-13 | Dow Agrosciences Llc | 4-((6-(2,4-difluorofenil)-1,1-difluoro-2-hidróxi-3(5-mercapto-1h-1,2,4-triazol-1-il)propil)piridin-3-il)óxi)benzonitrila e processos de preparação |
| EP3541794B1 (en) * | 2016-11-18 | 2021-07-14 | Dow AgroSciences LLC | 4-((6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-mercapto-1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile and processes of preparation |
| EP3555047A4 (en) * | 2016-11-18 | 2020-04-29 | Dow AgroSciences LLC | T-BUTYL-2-CARBAMOTHIOYL-2- (3- (5- (4-CYANOPHENOXY) PYRIDIN-2-YL) -2- (2,4-DIFLUORPHENYL) -3,3-DIFLUOR-2-HYDROXYPROPYL) HYDRAZIN- 1-CARBOXYLATE AND PRODUCTION METHOD |
| EP3541796A4 (en) * | 2016-11-18 | 2020-03-25 | Dow AgroSciences LLC | 4 - ((6- (2,4-DIFLUORPHENYL) -1,1-DIFLUOR-2-HYDROXY-3- (5-MERCAPTO-1H |
| BR112019009793A2 (pt) * | 2016-11-18 | 2019-08-06 | Dow Agrosciences Llc | 4-((6-(2-(2,4-difluorofenil)-1,1-difluoro-2-hidróxi-3-(5-mercapto-1h-1,2,4-triazol-1-il)propil)piridin-3-il)óxi)benzonitrila e processos de preparação |
| EP3541801A4 (en) * | 2016-11-18 | 2020-04-29 | Dow AgroSciences LLC | 4- (6- (2- (2,4-DIFLUORPHENYL) -1,1-DIFLUOR-2-HYDROXY-3- (5-MERCAPTO-1H |
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| WO2012177635A1 (en) | 2011-06-19 | 2012-12-27 | Viamet Pharmaceuticals, Inc. | Metalloenzyme inhibitor compounds |
| IN2014MN00093A (https=) | 2011-06-19 | 2015-06-19 | Viamet Pharmaceuticals Inc | |
| EA025266B1 (ru) | 2011-06-23 | 2016-12-30 | Ваймет Фармасьютикалс, Инк. | Соединения, ингибирующие металлоферменты |
| WO2013047308A1 (ja) * | 2011-09-27 | 2013-04-04 | 株式会社クレハ | アゾール誘導体、農園芸用薬剤および工業用材料保護剤、植物病害防除方法ならびに種子 |
| HK1223093A1 (zh) * | 2013-05-28 | 2017-07-21 | Viamet Pharmaceuticals (NC), Inc. | 杀真菌组合物 |
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2016
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- 2016-05-17 HK HK18112457.1A patent/HK1253073A1/zh unknown
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2017
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