CO2017012621A2 - Compuestos derivados de benzonitrilo, composición agronómica que los comprende y proceso para su obtención - Google Patents
Compuestos derivados de benzonitrilo, composición agronómica que los comprende y proceso para su obtenciónInfo
- Publication number
- CO2017012621A2 CO2017012621A2 CONC2017/0012621A CO2017012621A CO2017012621A2 CO 2017012621 A2 CO2017012621 A2 CO 2017012621A2 CO 2017012621 A CO2017012621 A CO 2017012621A CO 2017012621 A2 CO2017012621 A2 CO 2017012621A2
- Authority
- CO
- Colombia
- Prior art keywords
- benzonitrile
- obtaining
- compounds derived
- agronomic composition
- agronomic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Compuestos de la fórmula (I): en donde R1 es como se define en la presente, o una sal, un solvato, un profármaco o un hidrato aceptable del mismo. Los compuestos de la Fórmula I son inhibidores de metaloenzimas, tal como la lanosterol desmetilasa (CYP51).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562163106P | 2015-05-18 | 2015-05-18 | |
PCT/US2016/032877 WO2016187201A2 (en) | 2015-05-18 | 2016-05-17 | Antifungal compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
CO2017012621A2 true CO2017012621A2 (es) | 2018-04-30 |
Family
ID=57320616
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CONC2017/0012621A CO2017012621A2 (es) | 2015-05-18 | 2017-12-07 | Compuestos derivados de benzonitrilo, composición agronómica que los comprende y proceso para su obtención |
Country Status (25)
Country | Link |
---|---|
US (2) | US11051514B2 (es) |
EP (2) | EP3297998B1 (es) |
JP (1) | JP6908533B2 (es) |
KR (1) | KR20180000731A (es) |
CN (1) | CN107750248A (es) |
AR (1) | AR104695A1 (es) |
AU (2) | AU2016265932B2 (es) |
BR (1) | BR112017024463B1 (es) |
CA (1) | CA2986041C (es) |
CL (1) | CL2017002929A1 (es) |
CO (1) | CO2017012621A2 (es) |
CR (1) | CR20170574A (es) |
DK (1) | DK3297998T3 (es) |
EA (1) | EA034387B1 (es) |
EC (1) | ECSP17082683A (es) |
ES (1) | ES2776241T3 (es) |
HK (2) | HK1251569A1 (es) |
IL (1) | IL255605B (es) |
LT (1) | LT3297998T (es) |
MX (1) | MX2017014848A (es) |
PH (1) | PH12017502082A1 (es) |
TW (1) | TWI623527B (es) |
UA (1) | UA120784C2 (es) |
WO (1) | WO2016187201A2 (es) |
ZA (1) | ZA201707783B (es) |
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MX371291B (es) | 2014-03-19 | 2020-01-24 | Viamet Pharmaceuticals Nc Inc | 2-(2,4-difluorofenil)-1,1-difluoro-1-(5-sustituido-piridin-2-il)- 3-(1h-tetrazol-1-il)propan-2-oles y procedimientos para su preparacion. |
CA2942976C (en) | 2014-03-19 | 2022-05-10 | Viamet Pharmaceuticals, Inc. | Antifungal compound process |
CA2942231A1 (en) | 2014-03-19 | 2015-09-24 | Viamet Pharmaceuticals, Inc. | Antifungal compound process |
EP3119748A4 (en) | 2014-03-19 | 2017-08-30 | Viamet Pharmaceuticals, Inc. | Antifungal compound process |
CA2942982C (en) * | 2014-03-19 | 2023-09-19 | Viamet Pharmaceuticals, Inc. | 2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-substituted-pyridin-2-yl)-3-(1h-tetrazol-1-yl)propan-2-ols and processes for their preparation |
AU2015231208B2 (en) | 2014-03-19 | 2019-04-04 | Mycovia Pharmaceuticals, Inc. | Antifungal compound process |
CN109970629B (zh) | 2014-03-19 | 2023-04-11 | 迈科维亚医药公司 | 抗真菌化合物的制备方法 |
US10000465B2 (en) | 2014-03-19 | 2018-06-19 | Mycovia Pharmaceuticals, Inc. | Antifungal compound process |
CA2942932A1 (en) | 2014-03-19 | 2015-09-24 | Viamet Pharmaceuticals, Inc. | Antifungal compound process |
EA037521B1 (ru) | 2015-09-18 | 2021-04-07 | ВиПиЭс-3, ИНК. | Противогрибковые соединения и способы их получения |
EP3376865B1 (en) * | 2015-11-17 | 2021-04-14 | Dow Agrosciences LLC | 4-((6-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1h |
JP6898340B2 (ja) * | 2015-11-17 | 2021-07-07 | コルテバ アグリサイエンス エルエルシー | 4−((6−(2−(2,4−ジフルオロフェニル)−1,1−ジフルオロ−2−ヒドロキシ−3−(1h−1,2,4−トリアゾール−1−イル)プロピル)ピリジン−3−イル)オキシ)ベンゾニトリル及び調製方法 |
KR20180100313A (ko) * | 2015-11-17 | 2018-09-10 | 다우 아그로사이언시즈 엘엘씨 | 4-((6-(2-(2,4-디플루오로페닐)-1,1-디플루오로-2-히드록시-3-(1h-1,2,4-트리아졸-1-일)프로필)피리딘-3-일)옥시)벤조니트릴 및 제조방법 |
JP6987070B2 (ja) * | 2015-11-17 | 2021-12-22 | コルテバ アグリサイエンス エルエルシー | 4−((6−(2−(2,4−ジフルオロフェニル)−1,1−ジフルオロ−2−オキソエチル)ピリジン−3−イル)オキシ)ベンゾニトリル及び製造方法 |
BR112019009770A2 (pt) * | 2016-11-18 | 2019-08-06 | Dow Agrosciences Llc | 4-((6-(2-(2,4-difluorofenil)-1,1-difluoro-2-hidróxi-3-(-5-mercapto-1h-1,2,4-triazol-1-il)propil)piridin-3-il)óxi)benzonitrila e processos de preparação |
US20190276430A1 (en) * | 2016-11-18 | 2019-09-12 | Dow Agrosciences Llc | 4-((6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-mercapto-1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile and processes of preparation |
EP3541800A4 (en) * | 2016-11-18 | 2020-04-08 | Dow Agrosciences Llc | PROCESSES FOR THE PREPARATION OF 4 - ((6- (2,4-DIFLUOROPHENYL) -1,1-DIFLUORO-2-HYDROXY-3- (5-MERCAPTO-1H-1,2,4-TRIAZOL-1-YL) PROPYL ) PYRIDIN-3-YL) OXY) BENZONITRILE |
EP3541796A4 (en) * | 2016-11-18 | 2020-03-25 | Dow AgroSciences LLC | 4 - ((6- (2,4-DIFLUORPHENYL) -1,1-DIFLUOR-2-HYDROXY-3- (5-MERCAPTO-1H |
BR112019009767A2 (pt) * | 2016-11-18 | 2019-08-13 | Dow Agrosciences Llc | 4-((6-(2,4-difluorofenil)-1,1-difluoro-2-hidróxi-3(5-mercapto-1h-1,2,4-triazol-1-il)propil)piridin-3-il)óxi)benzonitrila e processos de preparação |
US20190276403A1 (en) * | 2016-11-18 | 2019-09-12 | Dow Agrosciences Llc | T-butyl 2-carbamothioyl-2-(3-(5-(4-cyanophenoxy)pyridin-2-yl)-2-(2,4-difluorophenyl)-3,3-difluoro-2-hydroxypropyl)hydrazine-1-carboxylate and processes of preparation |
EP3541797A4 (en) * | 2016-11-18 | 2020-04-29 | Dow AgroSciences LLC | 4 - ((6- (2- (2,4-DIFLUORPHENYL) -1,1-DIFLUOR-2-HYDROXY-3- (5-MERCAPTO-1H |
CN109963841A (zh) * | 2016-11-18 | 2019-07-02 | 美国陶氏益农公司 | 4-((6-(2-(2,4-二氟苯基)-1,1-二氟-2-羟基-3-(5-巯基-1h-1,2,4-三唑-1-基)丙基)吡啶-3-基)氧基)苄腈及制备方法 |
WO2018094140A1 (en) * | 2016-11-18 | 2018-05-24 | Vps-3, Inc. | 4-(6-(2-(2,4-difluorophenyl)-1.1-difluoro-2-hydroxy-3-(5-mercapto-1h-1,2,4-triazol-1-yl) propyl)pyridin-3-yl)oxy)benzonitrile and processes of preparation |
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TW201842851A (zh) * | 2017-05-02 | 2018-12-16 | 美商陶氏農業科學公司 | 用於穀類中的真菌防治之協同性混合物 |
WO2020007646A1 (en) | 2018-07-02 | 2020-01-09 | Basf Se | Pesticidal mixtures |
PL3817553T3 (pl) | 2018-07-02 | 2022-12-19 | Basf Se | Mieszaniny szkodnikobójcze |
WO2020020813A1 (en) | 2018-07-25 | 2020-01-30 | Bayer Aktiengesellschaft | Fungicidal active compound combinations |
US20210251232A1 (en) | 2018-08-08 | 2021-08-19 | Basf Se | Use of fungicidal active compound i derivative and mixtures thereof in seed application and treatment methods |
WO2020037109A1 (en) * | 2018-08-17 | 2020-02-20 | Dow Agrosciences Llc | Processes for fluorination |
WO2020078794A1 (en) | 2018-10-19 | 2020-04-23 | Basf Se | Ternary mixtures containing fenpropimorph, azoles and a multiside fungicide |
BR112021006011A2 (pt) | 2018-10-19 | 2021-06-29 | Basf Se | misturas fungicidas, composição pesticida, uso da mistura e método para controlar pragas fitopatogênicas |
EP3927164A1 (en) | 2019-02-20 | 2021-12-29 | Basf Se | Pesticidal mixtures comprising a pyrazole compound |
AU2020232258A1 (en) * | 2019-03-06 | 2021-08-26 | Corteva Agriscience Llc | A difluoro-(2-hydroxypropyl)pyridine compound as a fungicide for black sigatoka |
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2016
- 2016-05-17 MX MX2017014848A patent/MX2017014848A/es unknown
- 2016-05-17 JP JP2017559811A patent/JP6908533B2/ja active Active
- 2016-05-17 BR BR112017024463-2A patent/BR112017024463B1/pt active IP Right Grant
- 2016-05-17 US US15/574,775 patent/US11051514B2/en active Active
- 2016-05-17 LT LTEP16797145.6T patent/LT3297998T/lt unknown
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