ZA201004823B - Novel pyrazolo [3,4-d]pyrimidine derivatives as anti-cancer agents - Google Patents

Novel pyrazolo [3,4-d]pyrimidine derivatives as anti-cancer agents

Info

Publication number
ZA201004823B
ZA201004823B ZA2010/04823A ZA201004823A ZA201004823B ZA 201004823 B ZA201004823 B ZA 201004823B ZA 2010/04823 A ZA2010/04823 A ZA 2010/04823A ZA 201004823 A ZA201004823 A ZA 201004823A ZA 201004823 B ZA201004823 B ZA 201004823B
Authority
ZA
South Africa
Prior art keywords
cancer agents
pyrimidine derivatives
novel pyrazolo
pyrazolo
novel
Prior art date
Application number
ZA2010/04823A
Other languages
English (en)
Inventor
Subba Rao Pula
Durga Prasad Konakanchi
Lakshmi Ananthaneni
Ramakrishna Pilli
Reddy Muddasani Pulla
Kali Satya Bhujanga Rao Adibhatla
Chowdary Nannapaneni Venkaiah
Original Assignee
Natco Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Natco Pharma Ltd filed Critical Natco Pharma Ltd
Publication of ZA201004823B publication Critical patent/ZA201004823B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA2010/04823A 2008-01-11 2010-07-08 Novel pyrazolo [3,4-d]pyrimidine derivatives as anti-cancer agents ZA201004823B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN109CH2008 2008-01-11
PCT/IN2009/000037 WO2009098715A2 (en) 2008-01-11 2009-01-12 Novel pyrazolo [3, 4 -d] pyrimidine derivatives as anti -cancer agents

Publications (1)

Publication Number Publication Date
ZA201004823B true ZA201004823B (en) 2011-09-28

Family

ID=40933862

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2010/04823A ZA201004823B (en) 2008-01-11 2010-07-08 Novel pyrazolo [3,4-d]pyrimidine derivatives as anti-cancer agents

Country Status (18)

Country Link
US (1) US8349847B2 (cg-RX-API-DMAC7.html)
EP (1) EP2247596A2 (cg-RX-API-DMAC7.html)
JP (1) JP2011509290A (cg-RX-API-DMAC7.html)
KR (1) KR20100116607A (cg-RX-API-DMAC7.html)
CN (1) CN101965350A (cg-RX-API-DMAC7.html)
AP (1) AP2010005347A0 (cg-RX-API-DMAC7.html)
AU (1) AU2009211004C1 (cg-RX-API-DMAC7.html)
BR (1) BRPI0906475A2 (cg-RX-API-DMAC7.html)
CA (1) CA2711777A1 (cg-RX-API-DMAC7.html)
CO (1) CO6382174A2 (cg-RX-API-DMAC7.html)
EA (1) EA201070841A1 (cg-RX-API-DMAC7.html)
GE (1) GEP20135780B (cg-RX-API-DMAC7.html)
IL (1) IL206811A0 (cg-RX-API-DMAC7.html)
MA (1) MA32009B1 (cg-RX-API-DMAC7.html)
MX (1) MX2010007523A (cg-RX-API-DMAC7.html)
NZ (1) NZ586642A (cg-RX-API-DMAC7.html)
WO (1) WO2009098715A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA201004823B (cg-RX-API-DMAC7.html)

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TW201130842A (en) * 2009-12-18 2011-09-16 Incyte Corp Substituted fused aryl and heteroaryl derivatives as PI3K inhibitors
WO2011075643A1 (en) 2009-12-18 2011-06-23 Incyte Corporation Substituted heteroaryl fused derivatives as pi3k inhibitors
CA2796311A1 (en) 2010-04-14 2011-10-20 Incyte Corporation Fused derivatives as pi3k.delta. inhibitors
US9062055B2 (en) 2010-06-21 2015-06-23 Incyte Corporation Fused pyrrole derivatives as PI3K inhibitors
CA2822070C (en) 2010-12-20 2019-09-17 Incyte Corporation N-(1-(substituted-phenyl)ethyl)-9h-purin-6-amines as pi3k inhibitors
WO2012125629A1 (en) 2011-03-14 2012-09-20 Incyte Corporation Substituted diamino-pyrimidine and diamino-pyridine derivatives as pi3k inhibitors
WO2012135009A1 (en) 2011-03-25 2012-10-04 Incyte Corporation Pyrimidine-4,6-diamine derivatives as pi3k inhibitors
PH12021552978A1 (en) 2011-09-02 2022-08-22 Incyte Holdings Corp Heterocyclylamines as pi3k inhibitors
AR090548A1 (es) 2012-04-02 2014-11-19 Incyte Corp Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
CN102746309B (zh) * 2012-07-09 2013-06-05 四川大学 1-N-乙基-4-N-2′-取代酰基肼-1H-吡唑[3,4-d]嘧啶类衍生物及其制备方法和用途
CN102746307B (zh) * 2012-07-09 2013-07-31 四川大学 1-n-苄基别嘌醇衍生物及其制备方法和用途
CN103965202B (zh) * 2014-05-21 2016-01-20 邹宏丽 二环稠合杂环化合物、其制备方法及用途
US10077277B2 (en) 2014-06-11 2018-09-18 Incyte Corporation Bicyclic heteroarylaminoalkyl phenyl derivatives as PI3K inhibitors
LT3262046T (lt) 2015-02-27 2021-01-11 Incyte Corporation Pi3k inhibitoriaus druskos ir jų gamybos būdai
WO2016183060A1 (en) 2015-05-11 2016-11-17 Incyte Corporation Process for the synthesis of a phosphoinositide 3-kinase inhibitor
US9988401B2 (en) 2015-05-11 2018-06-05 Incyte Corporation Crystalline forms of a PI3K inhibitor
CN106008527B (zh) * 2016-06-29 2018-05-15 四川大学华西医院 吡唑并[3,4-d]嘧啶衍生物
CN107698596A (zh) * 2017-11-15 2018-02-16 双鹤药业（商丘）有限责任公司 一种别嘌醇的合成方法
CA3101323A1 (en) 2018-06-01 2019-12-05 Incyte Corporation Dosing regimen for the treatment of pi3k related disorders
JP2023508978A (ja) * 2019-12-23 2023-03-06 サンフォード バーナム プレビス メディカル ディスカバリー インスティテュート エクトヌクレオチドピロホスファターゼ／ホスホジエステラーゼ１（ｅｎｐｐ１）モジュレーター及びその使用
CN115304607B (zh) * 2022-07-06 2023-06-27 华南农业大学 吡唑并嘧啶衍生物的制备方法

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Also Published As

Publication number Publication date
EA201070841A1 (ru) 2011-02-28
AU2009211004A1 (en) 2009-08-13
WO2009098715A2 (en) 2009-08-13
US20100298351A1 (en) 2010-11-25
CA2711777A1 (en) 2009-08-13
AU2009211004A2 (en) 2011-01-27
JP2011509290A (ja) 2011-03-24
GEP20135780B (en) 2013-03-11
KR20100116607A (ko) 2010-11-01
MX2010007523A (es) 2010-08-18
CN101965350A (zh) 2011-02-02
WO2009098715A4 (en) 2009-12-10
NZ586642A (en) 2012-04-27
AU2009211004C1 (en) 2013-08-01
CO6382174A2 (es) 2012-02-15
IL206811A0 (en) 2010-12-30
WO2009098715A3 (en) 2009-10-15
EP2247596A2 (en) 2010-11-10
BRPI0906475A2 (pt) 2015-07-14
US8349847B2 (en) 2013-01-08
MA32009B1 (fr) 2011-01-03
AP2010005347A0 (en) 2010-08-31
AU2009211004B2 (en) 2011-09-01

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