BRPI0906475A2 - Compostos, processso para a preparação de um composto, composição farmacêutica e uso de um composto - Google Patents

Compostos, processso para a preparação de um composto, composição farmacêutica e uso de um composto

Info

Publication number
BRPI0906475A2
BRPI0906475A2 BRPI0906475-3A BRPI0906475A BRPI0906475A2 BR PI0906475 A2 BRPI0906475 A2 BR PI0906475A2 BR PI0906475 A BRPI0906475 A BR PI0906475A BR PI0906475 A2 BRPI0906475 A2 BR PI0906475A2
Authority
BR
Brazil
Prior art keywords
compound
preparing
compounds
pharmaceutical composition
pharmaceutical
Prior art date
Application number
BRPI0906475-3A
Other languages
English (en)
Portuguese (pt)
Inventor
Durga Prasad Konakonchi
Subba Rao Pula
Lakshmi Anathaneni
Ramakrishna Pilli
Muddasani Pulla Reddy
Bhujanga Rao Adibhatia Kali Satya
Nannapaneni Venkaiah Chowdary
Original Assignee
Natco Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Natco Pharma Ltd filed Critical Natco Pharma Ltd
Publication of BRPI0906475A2 publication Critical patent/BRPI0906475A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI0906475-3A 2008-01-11 2009-01-12 Compostos, processso para a preparação de um composto, composição farmacêutica e uso de um composto BRPI0906475A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN109CH2008 2008-01-11
PCT/IN2009/000037 WO2009098715A2 (en) 2008-01-11 2009-01-12 Novel pyrazolo [3, 4 -d] pyrimidine derivatives as anti -cancer agents

Publications (1)

Publication Number Publication Date
BRPI0906475A2 true BRPI0906475A2 (pt) 2015-07-14

Family

ID=40933862

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0906475-3A BRPI0906475A2 (pt) 2008-01-11 2009-01-12 Compostos, processso para a preparação de um composto, composição farmacêutica e uso de um composto

Country Status (18)

Country Link
US (1) US8349847B2 (cg-RX-API-DMAC7.html)
EP (1) EP2247596A2 (cg-RX-API-DMAC7.html)
JP (1) JP2011509290A (cg-RX-API-DMAC7.html)
KR (1) KR20100116607A (cg-RX-API-DMAC7.html)
CN (1) CN101965350A (cg-RX-API-DMAC7.html)
AP (1) AP2010005347A0 (cg-RX-API-DMAC7.html)
AU (1) AU2009211004C1 (cg-RX-API-DMAC7.html)
BR (1) BRPI0906475A2 (cg-RX-API-DMAC7.html)
CA (1) CA2711777A1 (cg-RX-API-DMAC7.html)
CO (1) CO6382174A2 (cg-RX-API-DMAC7.html)
EA (1) EA201070841A1 (cg-RX-API-DMAC7.html)
GE (1) GEP20135780B (cg-RX-API-DMAC7.html)
IL (1) IL206811A0 (cg-RX-API-DMAC7.html)
MA (1) MA32009B1 (cg-RX-API-DMAC7.html)
MX (1) MX2010007523A (cg-RX-API-DMAC7.html)
NZ (1) NZ586642A (cg-RX-API-DMAC7.html)
WO (1) WO2009098715A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA201004823B (cg-RX-API-DMAC7.html)

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PL2448938T3 (pl) 2009-06-29 2014-11-28 Incyte Holdings Corp Pirymidynony jako inhibitory PI3K
TW201130842A (en) * 2009-12-18 2011-09-16 Incyte Corp Substituted fused aryl and heteroaryl derivatives as PI3K inhibitors
WO2011075643A1 (en) 2009-12-18 2011-06-23 Incyte Corporation Substituted heteroaryl fused derivatives as pi3k inhibitors
CA2796311A1 (en) 2010-04-14 2011-10-20 Incyte Corporation Fused derivatives as pi3k.delta. inhibitors
US9062055B2 (en) 2010-06-21 2015-06-23 Incyte Corporation Fused pyrrole derivatives as PI3K inhibitors
CA2822070C (en) 2010-12-20 2019-09-17 Incyte Corporation N-(1-(substituted-phenyl)ethyl)-9h-purin-6-amines as pi3k inhibitors
WO2012125629A1 (en) 2011-03-14 2012-09-20 Incyte Corporation Substituted diamino-pyrimidine and diamino-pyridine derivatives as pi3k inhibitors
WO2012135009A1 (en) 2011-03-25 2012-10-04 Incyte Corporation Pyrimidine-4,6-diamine derivatives as pi3k inhibitors
PH12021552978A1 (en) 2011-09-02 2022-08-22 Incyte Holdings Corp Heterocyclylamines as pi3k inhibitors
AR090548A1 (es) 2012-04-02 2014-11-19 Incyte Corp Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
CN102746309B (zh) * 2012-07-09 2013-06-05 四川大学 1-N-乙基-4-N-2′-取代酰基肼-1H-吡唑[3,4-d]嘧啶类衍生物及其制备方法和用途
CN102746307B (zh) * 2012-07-09 2013-07-31 四川大学 1-n-苄基别嘌醇衍生物及其制备方法和用途
CN103965202B (zh) * 2014-05-21 2016-01-20 邹宏丽 二环稠合杂环化合物、其制备方法及用途
US10077277B2 (en) 2014-06-11 2018-09-18 Incyte Corporation Bicyclic heteroarylaminoalkyl phenyl derivatives as PI3K inhibitors
LT3262046T (lt) 2015-02-27 2021-01-11 Incyte Corporation Pi3k inhibitoriaus druskos ir jų gamybos būdai
WO2016183060A1 (en) 2015-05-11 2016-11-17 Incyte Corporation Process for the synthesis of a phosphoinositide 3-kinase inhibitor
US9988401B2 (en) 2015-05-11 2018-06-05 Incyte Corporation Crystalline forms of a PI3K inhibitor
CN106008527B (zh) * 2016-06-29 2018-05-15 四川大学华西医院 吡唑并[3,4-d]嘧啶衍生物
CN107698596A (zh) * 2017-11-15 2018-02-16 双鹤药业（商丘）有限责任公司 一种别嘌醇的合成方法
CA3101323A1 (en) 2018-06-01 2019-12-05 Incyte Corporation Dosing regimen for the treatment of pi3k related disorders
JP2023508978A (ja) * 2019-12-23 2023-03-06 サンフォード バーナム プレビス メディカル ディスカバリー インスティテュート エクトヌクレオチドピロホスファターゼ／ホスホジエステラーゼ１（ｅｎｐｐ１）モジュレーター及びその使用
CN115304607B (zh) * 2022-07-06 2023-06-27 华南农业大学 吡唑并嘧啶衍生物的制备方法

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US3000688A (en) 1961-09-19 Process for vatting of vat dyestuffs
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JPS5439096A (en) 1977-08-27 1979-03-24 Lion Dentifrice Co Ltd 11phenyll1hhpyrazolo*3*44d*pyrimidinee44 carbonitrile
US5877178A (en) 1991-04-08 1999-03-02 Duquesne University Of The Holy Ghost Pyrimidine derivatives and methods of making and using these derivatives
US5958930A (en) 1991-04-08 1999-09-28 Duquesne University Of The Holy Ghost Pyrrolo pyrimidine and furo pyrimidine derivatives
US5593997A (en) * 1995-05-23 1997-01-14 Pfizer Inc. 4-aminopyrazolo(3-,4-D)pyrimidine and 4-aminopyrazolo-(3,4-D)pyridine tyrosine kinase inhibitors
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ATE217873T1 (de) 1996-01-23 2002-06-15 Novartis Erfind Verwalt Gmbh Pyrrolopyrimidinen und verfahren zu deren herstellung
CH690773A5 (de) 1996-02-01 2001-01-15 Novartis Ag Pyrrolo(2,3-d)pyrimide und ihre Verwendung.
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WO1998007726A1 (en) 1996-08-23 1998-02-26 Novartis Ag Substituted pyrrolopyrimidines and processes for their preparation
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US6423871B1 (en) 1999-02-26 2002-07-23 University Of South Florida Efficient synthesis of secondary amines by selective alkylation of primary amines
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WO2001072751A1 (en) 2000-03-29 2001-10-04 Knoll Gesellschaft Mit Beschraenkter Haftung Pyrrolopyrimidines as tyrosine kinase inhibitors
US6680324B2 (en) 2000-12-01 2004-01-20 Osi Pharmaceuticals, Inc. Compounds specific to adenosine A1 receptors and uses thereof
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TWI238824B (en) 2001-05-14 2005-09-01 Novartis Ag 4-amino-5-phenyl-7-cyclobutyl-pyrrolo[2,3-d]pyrimidine derivatives
US20030114467A1 (en) 2001-06-21 2003-06-19 Shakespeare William C. Novel pyrazolo- and pyrrolo-pyrimidines and uses thereof
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US6939874B2 (en) 2001-08-22 2005-09-06 Amgen Inc. Substituted pyrimidinyl derivatives and methods of use
DE60304718T2 (de) 2002-08-06 2007-04-26 Astrazeneca Ab Kondensierte pyridine und pyrimidine mit tie2 (tek) aktivität
US20040138238A1 (en) 2002-08-08 2004-07-15 Dhanoa Dale S. Substituted aminopyrimidine compounds as neurokinin antagonists

Also Published As

Publication number Publication date
EA201070841A1 (ru) 2011-02-28
AU2009211004A1 (en) 2009-08-13
WO2009098715A2 (en) 2009-08-13
US20100298351A1 (en) 2010-11-25
CA2711777A1 (en) 2009-08-13
AU2009211004A2 (en) 2011-01-27
JP2011509290A (ja) 2011-03-24
GEP20135780B (en) 2013-03-11
KR20100116607A (ko) 2010-11-01
MX2010007523A (es) 2010-08-18
CN101965350A (zh) 2011-02-02
WO2009098715A4 (en) 2009-12-10
NZ586642A (en) 2012-04-27
AU2009211004C1 (en) 2013-08-01
CO6382174A2 (es) 2012-02-15
IL206811A0 (en) 2010-12-30
WO2009098715A3 (en) 2009-10-15
EP2247596A2 (en) 2010-11-10
US8349847B2 (en) 2013-01-08
MA32009B1 (fr) 2011-01-03
AP2010005347A0 (en) 2010-08-31
AU2009211004B2 (en) 2011-09-01
ZA201004823B (en) 2011-09-28

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.