ZA200906064B - Tricyclic compounds and their use as glucocorticoid receptor modulators - Google Patents
Tricyclic compounds and their use as glucocorticoid receptor modulatorsInfo
- Publication number
- ZA200906064B ZA200906064B ZA200906064A ZA200906064A ZA200906064B ZA 200906064 B ZA200906064 B ZA 200906064B ZA 200906064 A ZA200906064 A ZA 200906064A ZA 200906064 A ZA200906064 A ZA 200906064A ZA 200906064 B ZA200906064 B ZA 200906064B
- Authority
- ZA
- South Africa
- Prior art keywords
- receptor modulators
- glucocorticoid receptor
- tricyclic compounds
- tricyclic
- compounds
- Prior art date
Links
- 229940117965 Glucocorticoid receptor modulator Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Child & Adolescent Psychology (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US88798107P | 2007-02-02 | 2007-02-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200906064B true ZA200906064B (en) | 2010-05-26 |
Family
ID=39315208
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200906064A ZA200906064B (en) | 2007-02-02 | 2009-09-01 | Tricyclic compounds and their use as glucocorticoid receptor modulators |
ZA200906060A ZA200906060B (en) | 2007-02-02 | 2009-09-01 | Tricyclic Compounds and their use as glucocorticoid receptor modulators |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200906060A ZA200906060B (en) | 2007-02-02 | 2009-09-01 | Tricyclic Compounds and their use as glucocorticoid receptor modulators |
Country Status (43)
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998003167A1 (en) | 1996-07-24 | 1998-01-29 | Warner-Lambert Company | Isobutylgaba and its derivatives for the treatment of pain |
RS51970B (en) | 2007-02-02 | 2012-02-29 | Pfizer Products Inc. | TRICYCLIC UNITS AND THEIR USE AS MODULATORS OF GLUCOCORTICOID RECEPTORS |
AP2744A (en) * | 2008-07-28 | 2013-09-30 | Pfizer | Phenanthrenone compounds, compositions and methods |
WO2010059894A1 (en) * | 2008-11-21 | 2010-05-27 | Bridge Pharma, Inc. | Ocular formulations of norketotifen |
US20100136094A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for modulating inflammation |
US20100137247A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Anti-inflammatory compositions and methods |
US20100136095A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for modulating inflammation |
US20100136096A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for modulating inflammation |
US20100137246A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Anti-inflammatory compositions and methods |
US20100136097A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for modulating inflammation |
US20100135983A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Anti-inflammatory compositions and methods |
US20130116284A1 (en) | 2010-05-10 | 2013-05-09 | Radikal Therapeutics Inc. | Lipoic acid and nitroxide derivatives and uses thereof |
EP2609097A4 (en) * | 2010-08-27 | 2014-04-16 | Corcept Therapeutics Inc | AZADECALINE PYRIDYL-AMINE MODULATORS |
JP2014509592A (ja) * | 2011-03-15 | 2014-04-21 | アッヴィ・インコーポレイテッド | 核ホルモン受容体モジュレーター |
US8545904B1 (en) | 2012-06-05 | 2013-10-01 | Liquid Innovators, LLC | Topical composition containing Carapa (andiroba) oil for psoriasis and other related dermatological disorders |
US9227901B2 (en) | 2012-07-05 | 2016-01-05 | Abbvie Inc. | Process for preparing bicyclic amine derivatives |
TW201422590A (zh) | 2012-09-07 | 2014-06-16 | Abbvie Inc | 雜環核激素受體調節劑 |
EP2935284A4 (en) | 2012-12-21 | 2016-04-27 | Abbvie Inc | HETEROCYCLIC MODULATORS OF HORMONE NUCLEAR RECEPTORS |
GB2541140A (en) | 2014-05-16 | 2017-02-08 | Liqwd Inc | Keratin treatment formulations and methods |
US9597284B2 (en) | 2014-10-20 | 2017-03-21 | Oyster Point Pharma, Inc. | Dry eye treatments |
CN104591988A (zh) * | 2014-12-29 | 2015-05-06 | 甘肃省化工研究院 | 6-溴-2-萘满酮的合成方法 |
US10722513B2 (en) | 2015-03-23 | 2020-07-28 | The University Of Melbourne | Treatment of respiratory diseases |
PT3439661T (pt) | 2016-04-07 | 2021-09-30 | Oyster Point Pharma Inc | Métodos de tratamento de condições oculares |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2576025B1 (fr) | 1985-01-14 | 1987-01-23 | Roussel Uclaf | Nouveaux steroides substitues en position 10, leur procede et les intermediaires de preparation, leur application comme medicaments, les compositions pharmaceutiques les contenant |
FR2600450B1 (fr) * | 1986-06-19 | 1988-08-26 | Pechiney Aluminium | Procede de marquage individuel des anodes precuites pour la production electrolytique d'aluminium |
GB9518953D0 (en) | 1995-09-15 | 1995-11-15 | Pfizer Ltd | Pharmaceutical formulations |
IL122740A (en) | 1997-01-15 | 2003-09-17 | Akzo Nobel Nv | 16-hydroxy-11-(substituted phenyl)-estra-9,4-diene derivatives, their preparation and pharmaceutical compositions containing them |
OA11877A (en) * | 1999-04-30 | 2006-03-29 | Pfizer Prod Inc | Glucocorticoid receptor modulators. |
WO2001005229A1 (en) | 1999-07-15 | 2001-01-25 | The General Hospital Corporation | Non-defective epstein-barr viral vector |
IL180679A0 (en) * | 2000-10-27 | 2009-02-11 | Pfizer Prod Inc | Process for the preparation of non-steroidal glucocorticoid receptor modulators |
ES2262612T3 (es) | 2000-10-28 | 2006-12-01 | Pfizer Products Inc. | Moduladpres del receptor de glucocorticoides. |
ATE303369T1 (de) | 2000-10-30 | 2005-09-15 | Pfizer Prod Inc | Glucocorticoid rezeptor modulatoren |
KR100793464B1 (ko) * | 2000-11-20 | 2008-01-14 | 시게이트 테크놀로지 엘엘씨 | Rfid 태그 및 이를 디스크 드라이브에 부착하는 방법 |
CA2450748A1 (en) | 2001-06-22 | 2003-01-03 | Pfizer Products Inc. | Pharmaceutical compositions containing polymer and drug assemblies |
JP2005501882A (ja) | 2001-08-31 | 2005-01-20 | コーセプト セラピューティクス, インコーポレイテッド | ダウン症候群を有する成人において認知低下を阻害する方法 |
ATE426593T1 (de) | 2001-09-27 | 2009-04-15 | Univ Liege | Pyridinsulfonamidderivate, deren herstellungsverfahren und verwendung |
DE10164366C1 (de) * | 2001-12-28 | 2003-06-05 | Rehau Ag & Co | Permanentkathode |
WO2003063833A1 (en) | 2002-02-01 | 2003-08-07 | Pfizer Products Inc. | Pharmaceutical compositions of amorphous dispersions of drugs and lipophilic microphase-forming materials |
JP2005535664A (ja) | 2002-07-02 | 2005-11-24 | コーセプト セラピューティクス, インコーポレイテッド | インターフェロン−α治療に関連した精神病を処置するための方法 |
DK1521733T3 (da) | 2002-07-08 | 2014-10-13 | Pfizer Prod Inc | Modulatorer af glucocorticoid receptoren |
AU2003291314B2 (en) | 2002-11-05 | 2007-07-26 | Corcept Therapeutics, Inc. | Methods for treating migraine |
AU2004208842B2 (en) | 2003-02-04 | 2009-05-28 | Corcept Therapeutics, Inc. | Antiglucocorticoids for the treatment of postpartum psychosis |
US8097606B2 (en) | 2003-07-23 | 2012-01-17 | Corcept Therapeutics, Inc. | Antiglucocorticoids for the treatment of catatonia |
US20050080061A1 (en) | 2003-07-23 | 2005-04-14 | Corcept Therapeutics, Inc. | Antiglucocorticoid therapy for the prevention of neurological damage in premature infants |
TW200512181A (en) | 2003-09-26 | 2005-04-01 | Tanabe Seiyaku Co | Amide-type carboxamide derivatives |
WO2005047524A2 (en) * | 2003-11-10 | 2005-05-26 | The Scripps Research Institute | Compositions and methods for inducing cell dedifferentiation |
JP2007511501A (ja) * | 2003-11-13 | 2007-05-10 | ファイザー・プロダクツ・インク | グルココルチコイド受容体調節剤として有用なオクタヒドロフェナンスレンヒドラジド誘導体 |
TWI370129B (en) | 2005-02-14 | 2012-08-11 | Msd Oss Bv | Non steroidal glucocorticoid receptor modulators |
CA2649894A1 (en) | 2006-05-02 | 2007-11-15 | Corcept Therapeutics, Inc. | The use of a glucocorticoid receptor ii antagonist to treat depression in patients taking il-2 |
RS51970B (en) | 2007-02-02 | 2012-02-29 | Pfizer Products Inc. | TRICYCLIC UNITS AND THEIR USE AS MODULATORS OF GLUCOCORTICOID RECEPTORS |
UZ4378C (en) * | 2007-02-02 | 2011-07-29 | Pfizer Prod Inc | Tricyclic compounds and their use as glucocorticoid receptor modulators |
-
2008
- 2008-01-25 RS RS20110429A patent/RS51970B/en unknown
- 2008-01-25 AU AU2008211613A patent/AU2008211613B2/en not_active Ceased
- 2008-01-25 CA CA2676670A patent/CA2676670C/en not_active Expired - Fee Related
- 2008-01-25 GE GEAP200811399A patent/GEP20125404B/en unknown
- 2008-01-25 AP AP2009004942A patent/AP2455A/xx active
- 2008-01-25 EP EP08702351A patent/EP2114970B1/en active Active
- 2008-01-25 MY MYPI20093089A patent/MY146087A/en unknown
- 2008-01-25 BR BRPI0808634-6A patent/BRPI0808634A2/pt not_active IP Right Cessation
- 2008-01-25 EA EA200970666A patent/EA016494B1/ru not_active IP Right Cessation
- 2008-01-25 AT AT08702351T patent/ATE518872T1/de active
- 2008-01-25 PL PL08702351T patent/PL2114970T3/pl unknown
- 2008-01-25 MY MYPI20123293 patent/MY153057A/en unknown
- 2008-01-25 MX MX2009008284A patent/MX2009008284A/es active IP Right Grant
- 2008-01-25 DK DK08702351.1T patent/DK2114970T3/da active
- 2008-01-25 ES ES08702351T patent/ES2368286T3/es active Active
- 2008-01-25 CN CN2008800052954A patent/CN101616925B/zh not_active Expired - Fee Related
- 2008-01-25 NZ NZ578638A patent/NZ578638A/en not_active IP Right Cessation
- 2008-01-25 SI SI200830393T patent/SI2114970T1/sl unknown
- 2008-01-25 UA UAA200907728A patent/UA94639C2/ru unknown
- 2008-01-25 JP JP2009547778A patent/JP4599462B2/ja not_active Expired - Fee Related
- 2008-01-25 WO PCT/IB2008/000229 patent/WO2008093227A1/en active Application Filing
- 2008-01-25 KR KR1020097018289A patent/KR101107949B1/ko not_active IP Right Cessation
- 2008-01-25 PT PT08702351T patent/PT2114970E/pt unknown
- 2008-01-28 KR KR1020097018294A patent/KR101114682B1/ko not_active IP Right Cessation
- 2008-01-28 UA UAA200907730A patent/UA95332C2/uk unknown
- 2008-01-28 PT PT08702358T patent/PT2114888E/pt unknown
- 2008-01-28 GE GEAP200811398A patent/GEP20125426B/en unknown
- 2008-01-28 CN CN2008800056527A patent/CN101616896B/zh not_active Expired - Fee Related
- 2008-01-28 ES ES08702358T patent/ES2353822T3/es active Active
- 2008-01-28 MY MYPI20093135A patent/MY148780A/en unknown
- 2008-01-28 RS RS20110008A patent/RS51646B/en unknown
- 2008-01-31 PE PE2008000231A patent/PE20081736A1/es not_active Application Discontinuation
- 2008-01-31 US US12/023,323 patent/US7547714B2/en not_active Expired - Fee Related
- 2008-01-31 US US12/023,362 patent/US7598231B2/en not_active Expired - Fee Related
- 2008-02-01 CL CL200800329A patent/CL2008000329A1/es unknown
- 2008-02-01 HN HN2008000178A patent/HN2008000178A/es unknown
- 2008-02-01 AR ARP080100424A patent/AR065134A1/es active IP Right Grant
- 2008-02-01 TW TW097104074A patent/TWI373466B/zh not_active IP Right Cessation
- 2008-02-01 TW TW097104089A patent/TWI347842B/zh active
- 2008-02-01 CL CL200800330A patent/CL2008000330A1/es unknown
- 2008-02-01 HN HN2008000179A patent/HN2008000179A/es unknown
- 2008-02-01 AR ARP080100425A patent/AR065135A1/es active IP Right Grant
- 2008-02-01 PE PE2008000234A patent/PE20090113A1/es not_active Application Discontinuation
-
2009
- 2009-05-08 US US12/437,704 patent/US8158660B2/en not_active Expired - Fee Related
- 2009-07-20 IL IL199972A patent/IL199972A/en active IP Right Grant
- 2009-07-21 US US12/506,825 patent/US7786097B2/en not_active Expired - Fee Related
- 2009-07-23 CR CR10948A patent/CR10948A/es not_active IP Right Cessation
- 2009-07-23 CR CR10949A patent/CR10949A/es not_active IP Right Cessation
- 2009-07-24 CU CU20090133A patent/CU20090133A7/es active IP Right Grant
- 2009-07-24 CU CU2009000132A patent/CU23848B1/es active IP Right Grant
- 2009-07-29 DO DO2009000190A patent/DOP2009000190A/es unknown
- 2009-07-29 NI NI200900149A patent/NI200900149A/es unknown
- 2009-07-29 NI NI200900148A patent/NI200900148A/es unknown
- 2009-07-30 GT GT200900210A patent/GT200900210A/es unknown
- 2009-07-30 SV SV2009003346A patent/SV2009003346A/es not_active Application Discontinuation
- 2009-07-30 GT GT200900209A patent/GT200900209A/es unknown
- 2009-07-31 MA MA32128A patent/MA31158B1/fr unknown
- 2009-07-31 EC EC2009009552A patent/ECSP099552A/es unknown
- 2009-07-31 MA MA32127A patent/MA31117B1/fr unknown
- 2009-07-31 EC EC2009009553A patent/ECSP099553A/es unknown
- 2009-07-31 TN TNP2009000324A patent/TN2009000324A1/fr unknown
- 2009-07-31 CO CO09079796A patent/CO6190603A2/es active IP Right Grant
- 2009-07-31 CO CO09079789A patent/CO6220937A2/es active IP Right Grant
- 2009-07-31 SV SV2009003349A patent/SV2009003349A/es active IP Right Grant
- 2009-09-01 ZA ZA200906064A patent/ZA200906064B/xx unknown
- 2009-09-01 ZA ZA200906060A patent/ZA200906060B/xx unknown
-
2010
- 2010-02-12 HK HK10101635.7A patent/HK1135108A1/xx not_active IP Right Cessation
- 2010-12-02 CY CY20101101109T patent/CY1110962T1/el unknown
-
2011
- 2011-08-17 CY CY20111100784T patent/CY1111758T1/el unknown
- 2011-10-03 HR HR20110702T patent/HRP20110702T1/hr unknown
- 2011-12-21 US US13/333,104 patent/US8445520B2/en not_active Expired - Fee Related
-
2013
- 2013-04-16 US US13/863,534 patent/US20140142316A1/en not_active Abandoned
-
2014
- 2014-07-01 US US14/320,674 patent/US8901310B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AP2455A (en) | Tricyclic compounds and their use as glucocorticoid receptor modulators | |
IL188809A0 (en) | Tricyclic benzimidazoles and their use as metabotropic glutamate receptor modulators | |
EP2179061A4 (en) | GREAT LIKE RECEPTOR MODULATORS | |
HK1135094A1 (en) | Tricyclic compounds and their use as glucocorticoid receptor modulators | |
HRP20130374T1 (en) | Pyrrolidin-2-one derivatives as androgen receptor modulators | |
IL211821A0 (en) | The compounds as the estrogen related receptors modulators and the uses thereof | |
SI2094658T1 (sl) | Spojine tetrahidrociklopenta(b)indola kot modulatorji androgenskega receptorja | |
GB0701992D0 (en) | Grehlin Receptor Modulators | |
GB2462235B8 (en) | Receptor modulators exhibiting neuroprotective andmemory enhancing activities | |
EP2166848A4 (en) | SPIROINDOLINES AS MODULATORS OF CHEMOKINE RECEPTORS | |
IL211822A0 (en) | The compounds as the estrogen related receptors modulators and the uses thereof | |
HUP0700269A2 (en) | Pyrimidinyl-piperazines useful as d3/d2 receptor ligands, pharmaceutical compositions containing them and their use | |
EP2139489A4 (en) | Mineralocorticoid receptor modulators | |
IL184374A0 (en) | Non steroidal glucocorticoid receptor modulators | |
EP2229167A4 (en) | MINERALCORTICOIDREZEPTORMODULATOREN | |
EP2170874A4 (en) | NEW COMPOUNDS AND THEIR USE | |
EP2273266A4 (en) | PARASPORIN-1 RECEPTOR AND USE THEREOF | |
ZA200907546B (en) | New progesterone receptor modulators | |
GB0807710D0 (en) | Receptor and modulators thereof |