ZA200802184B - Use of peptides that bind to TPO receptor - Google Patents

Use of peptides that bind to TPO receptor

Info

Publication number
ZA200802184B
ZA200802184B ZA200802184A ZA200802184A ZA200802184B ZA 200802184 B ZA200802184 B ZA 200802184B ZA 200802184 A ZA200802184 A ZA 200802184A ZA 200802184 A ZA200802184 A ZA 200802184A ZA 200802184 B ZA200802184 B ZA 200802184B
Authority
ZA
South Africa
Prior art keywords
peptides
bind
tpo receptor
tpo
receptor
Prior art date
Application number
ZA200802184A
Other languages
English (en)
Inventor
Brian R Macdonald
Yurkow Edward John
Weis Jeffrey Kenneth
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37734435&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200802184(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of ZA200802184B publication Critical patent/ZA200802184B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA200802184A 2005-08-09 2008-03-07 Use of peptides that bind to TPO receptor ZA200802184B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/200,416 US7723295B2 (en) 2003-08-28 2005-08-09 Peptides and compounds that bind to a receptor

Publications (1)

Publication Number Publication Date
ZA200802184B true ZA200802184B (en) 2009-08-26

Family

ID=37734435

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200802184A ZA200802184B (en) 2005-08-09 2008-03-07 Use of peptides that bind to TPO receptor

Country Status (35)

Country Link
US (1) US7723295B2 (pt)
EP (1) EP1957517B1 (pt)
JP (1) JP2009504650A (pt)
KR (1) KR20080048026A (pt)
CN (1) CN101287749A (pt)
AR (1) AR055114A1 (pt)
AU (1) AU2006280230B2 (pt)
BR (1) BRPI0614647A2 (pt)
CA (1) CA2618958A1 (pt)
CR (1) CR9798A (pt)
CY (1) CY1114032T1 (pt)
DK (1) DK1957517T3 (pt)
EA (1) EA200800535A1 (pt)
EC (1) ECSP088169A (pt)
ES (1) ES2419005T3 (pt)
GT (1) GT200600361A (pt)
HK (1) HK1123811A1 (pt)
HR (1) HRP20130518T1 (pt)
IL (1) IL189361A (pt)
JO (1) JO2859B1 (pt)
MY (1) MY152177A (pt)
NI (1) NI200800040A (pt)
NO (1) NO344405B1 (pt)
NZ (1) NZ565497A (pt)
PE (1) PE20070416A1 (pt)
PL (1) PL1957517T3 (pt)
PT (1) PT1957517E (pt)
RS (1) RS52802B (pt)
SI (1) SI1957517T1 (pt)
SV (1) SV2008002648A (pt)
TW (1) TWI400081B (pt)
UA (1) UA96418C2 (pt)
UY (1) UY29736A1 (pt)
WO (1) WO2007021572A2 (pt)
ZA (1) ZA200802184B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7091311B2 (en) * 1996-06-07 2006-08-15 Smithkline Beecham Corporation Peptides and compounds that bind to a receptor
DK1542714T3 (da) * 2002-09-18 2014-05-26 Janssen Pharmaceuticals Inc Fremgangsmåder til forøgelse af produktion af blodplader og hæmatopoietiske stamceller
US20040149235A1 (en) * 2002-10-04 2004-08-05 Pogue Albert S. Apparatus and method for removal of waste from animal production facilities
US7615533B2 (en) * 2004-08-16 2009-11-10 Janssen Pharmaceutica N.V. TPO peptide compounds for treatment of anemia
AU2007208226A1 (en) * 2006-01-25 2007-08-02 Amgen Inc. Thrombopoietic compounds
CA2726603A1 (en) * 2008-06-03 2009-12-10 Janssen Pharmaceutica Nv Dosing regimen
JP5709113B2 (ja) * 2011-06-23 2015-04-30 株式会社島津製作所 分岐型両親媒性ブロックポリマー、それを用いた分子集合体及び薬剤搬送システム
WO2019023418A1 (en) 2017-07-26 2019-01-31 Janssen Pharmaceutica Nv METHODS FOR PROTECTING VASCULAR INTEGRITY INDUCED BY TARGETED RADIOTHERAPY
MX2021008942A (es) 2019-01-25 2021-08-24 Janssen Pharmaceutica Nv Metodos para mitigar efectos toxicos vesicantes y gas caustico.
US20200237872A1 (en) 2019-01-25 2020-07-30 Janssen Pharmaceutica Nv Methods of enhancing protection against organ and vascular injury, hematopoietic recovery and survival in response to total body radiation/chemical exposure
MX2021008943A (es) 2019-01-25 2021-11-04 Janssen Pharmaceutica Nv Metodos para mitigar la lesion hepatica y promover la hipertrofia hepatica, la regeneracion e injerto celular en conjunto con tratamientos de radiacion y/o radiomimeticos.
CA3234340A1 (en) 2021-10-01 2023-04-06 Janssen Pharmaceutica N.V. Methods of increasing progenitor cell production
WO2024095178A1 (en) 2022-11-01 2024-05-10 Janssen Pharmaceutica Nv Thrombopoietin mimetic for use in the treatment of acute liver failure

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5326558A (en) 1989-08-08 1994-07-05 Genetics Institute, Inc. Megakaryocytopoietic factor
IL96477A0 (en) 1989-12-01 1991-08-16 Amgen Inc Megakaryocyte production
DK167813B1 (da) 1989-12-07 1993-12-20 Carlbiotech Ltd As Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat
US5571508A (en) 1989-12-18 1996-11-05 Amrad Corporation Limited Method for the treatment of thrombocytopenia and pharmaceutical compositions useful therefor
IT1241395B (it) 1990-04-02 1994-01-10 Eniricerche Spa Composti immunogenici,il procedimento per la loro sintesi e loro impiego per la preparazione di vaccini antimalaria
US5141851A (en) 1990-04-18 1992-08-25 Board Of Regents, The University Of Texas System Isolated farnesyl protein transferase enzyme
US5250732A (en) 1991-07-18 1993-10-05 Genentech, Inc. Ketamine analogues for treatment of thrombocytopenia
US5270170A (en) 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
JPH07507806A (ja) 1992-06-11 1995-08-31 アルカーメス　コントロールド　セラピューティクス，インコーポレイテッド エリスロポエチン薬物送達システム
JP3401005B2 (ja) 1992-12-11 2003-04-28 ユニバーシティ オブ フロリダ 有害生物の防除のための材料および方法
WO1995011922A1 (en) 1993-10-29 1995-05-04 Affymax Technologies N.V. In vitro peptide and antibody display libraries
SG47030A1 (en) 1994-01-03 1998-03-20 Genentech Inc Thrombopoietin
WO1995021919A2 (en) 1994-02-14 1995-08-17 Kirin Brewery Company, Limited Protein having tpo activity
EP0723456A1 (en) 1994-02-14 1996-07-31 The University Of Washington Methods for stimulating erythropoiesis using thrombopoietin
EP0668352A1 (en) 1994-02-14 1995-08-23 Kirin Brewery Company, Ltd. Protein having TPO activity
CZ221496A3 (en) 1994-02-14 1997-07-16 Zymogenetics Inc Haematopoetic protein, materials and processes for preparing thereof
CN1103782C (zh) 1994-03-31 2003-03-26 安姆根有限公司 单聚乙二醇化的mgdf多肽
US5571686A (en) 1994-04-14 1996-11-05 Massachusetts Institute Of Technology Method of using megapoietin for prolonging the survival & viability of platlets
WO1996017062A1 (en) 1994-11-30 1996-06-06 Zymogenetics, Inc. Low molecular weight thrombopoietin
ES2276401T3 (es) 1995-04-26 2007-06-16 Kyowa Hakko Kogyo Co., Ltd. Proteinas de fusion g-csf tpo.
US5869451A (en) 1995-06-07 1999-02-09 Glaxo Group Limited Peptides and compounds that bind to a receptor
US6251864B1 (en) * 1995-06-07 2001-06-26 Glaxo Group Limited Peptides and compounds that bind to a receptor
EP2055712A1 (en) 1995-06-07 2009-05-06 Glaxo Group Limited Peptides and compounds that bind to a thrombopoietin receptor
US6060052A (en) 1995-10-30 2000-05-09 Systemix, Inc. Methods for use of Mpl ligands with primitive human hematopoietic stem cells
US5932546A (en) 1996-10-04 1999-08-03 Glaxo Wellcome Inc. Peptides and compounds that bind to the thrombopoietin receptor
ES2279769T3 (es) 1999-09-24 2007-09-01 Smithkline Beecham Corporation Mimeticos de trombopoyetina.
AU2002307062A1 (en) 2001-04-02 2002-10-15 Purdue Pharma L.P. Thrombopoietin (tpo) synthebody for stimulation of platelet production
DK1542714T3 (da) 2002-09-18 2014-05-26 Janssen Pharmaceuticals Inc Fremgangsmåder til forøgelse af produktion af blodplader og hæmatopoietiske stamceller
CN102241742B (zh) * 2003-08-28 2014-04-02 奥索-麦克尼尔药品公司 结合血小板生成素受体的肽和化合物

Also Published As

Publication number Publication date
DK1957517T3 (da) 2013-04-08
WO2007021572A3 (en) 2007-06-07
KR20080048026A (ko) 2008-05-30
SI1957517T1 (sl) 2013-07-31
SV2008002648A (es) 2008-11-28
US20060040866A1 (en) 2006-02-23
CR9798A (es) 2008-09-09
GT200600361A (es) 2007-03-14
EA200800535A1 (ru) 2008-08-29
US7723295B2 (en) 2010-05-25
NO344405B1 (no) 2019-12-02
ES2419005T3 (es) 2013-08-19
NO20081298L (no) 2008-04-23
CY1114032T1 (el) 2016-07-27
MY152177A (en) 2014-08-15
HK1123811A1 (en) 2009-06-26
EP1957517B1 (en) 2013-03-20
UY29736A1 (es) 2006-12-29
EP1957517A2 (en) 2008-08-20
CA2618958A1 (en) 2007-02-22
TWI400081B (zh) 2013-07-01
JP2009504650A (ja) 2009-02-05
AU2006280230A1 (en) 2007-02-22
PE20070416A1 (es) 2007-06-13
WO2007021572A2 (en) 2007-02-22
CN101287749A (zh) 2008-10-15
HRP20130518T1 (hr) 2013-07-31
PL1957517T3 (pl) 2013-08-30
TW200744626A (en) 2007-12-16
BRPI0614647A2 (pt) 2011-04-12
ECSP088169A (es) 2008-03-26
IL189361A0 (en) 2008-06-05
IL189361A (en) 2015-11-30
NI200800040A (es) 2010-11-25
UA96418C2 (ru) 2011-11-10
AU2006280230B2 (en) 2012-11-08
AR055114A1 (es) 2007-08-08
JO2859B1 (en) 2015-03-15
NZ565497A (en) 2011-10-28
PT1957517E (pt) 2013-05-28
RS52802B (en) 2013-10-31

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