ZA200705002B - Substituted piperazines as CB1 antagonists - Google Patents

Substituted piperazines as CB1 antagonists

Info

Publication number
ZA200705002B
ZA200705002B ZA200705002A ZA200705002A ZA200705002B ZA 200705002 B ZA200705002 B ZA 200705002B ZA 200705002 A ZA200705002 A ZA 200705002A ZA 200705002 A ZA200705002 A ZA 200705002A ZA 200705002 B ZA200705002 B ZA 200705002B
Authority
ZA
South Africa
Prior art keywords
antagonists
substituted piperazines
piperazines
substituted
Prior art date
Application number
ZA200705002A
Other languages
English (en)
Inventor
Eric J Gilbert
Jack D Scott
William J Greenlee
Michael W Miller
Andrew W Stamford
Weinstein Jay
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of ZA200705002B publication Critical patent/ZA200705002B/xx

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    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
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    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings

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  • Chemical & Material Sciences (AREA)
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  • Health & Medical Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA200705002A 2004-12-03 2007-06-01 Substituted piperazines as CB1 antagonists ZA200705002B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63310604P 2004-12-03 2004-12-03

Publications (1)

Publication Number Publication Date
ZA200705002B true ZA200705002B (en) 2008-09-25

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ZA200705002A ZA200705002B (en) 2004-12-03 2007-06-01 Substituted piperazines as CB1 antagonists

Country Status (18)

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US (2) US7700597B2 (ko)
EP (1) EP1819684B1 (ko)
JP (2) JP5254620B2 (ko)
KR (1) KR101351209B1 (ko)
CN (3) CN101115726A (ko)
AR (1) AR054998A1 (ko)
AU (2) AU2005311930B9 (ko)
CA (1) CA2589483C (ko)
ES (1) ES2435790T3 (ko)
HK (1) HK1112457A1 (ko)
IL (1) IL183538A (ko)
MX (1) MX2007006695A (ko)
MY (1) MY144301A (ko)
NZ (1) NZ555320A (ko)
SG (1) SG163577A1 (ko)
TW (1) TWI343379B (ko)
WO (1) WO2006060461A1 (ko)
ZA (1) ZA200705002B (ko)

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RU2009108280A (ru) 2006-08-08 2010-09-20 Санофи-Авентис (Fr) Ариламиноарилалкилзамещенные имидазолидин-2,4-дионы, способы их получения, содержащие эти соединения лекарственные средства и их применение
BRPI0718515A2 (pt) 2006-09-25 2013-11-19 Boehringer Ingelheim Int Compostos que modulam o receptor cb2
TW200831080A (en) * 2006-12-15 2008-08-01 Irm Llc Compounds and compositions as inhibitors of cannabinoid receptor 1 activity
WO2008099715A1 (ja) * 2007-02-09 2008-08-21 Kaneka Corporation 光学活性２－アリールピペラジン誘導体の製造法
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EP1819684B1 (en) 2013-08-07
KR20070090176A (ko) 2007-09-05
MY144301A (en) 2011-08-29
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AU2005311930B9 (en) 2009-09-10
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