HK1112457A1 - Substituted piperazines as cb1 antagonists - Google Patents

Substituted piperazines as cb1 antagonists

Info

Publication number
HK1112457A1
HK1112457A1 HK08101323.8A HK08101323A HK1112457A1 HK 1112457 A1 HK1112457 A1 HK 1112457A1 HK 08101323 A HK08101323 A HK 08101323A HK 1112457 A1 HK1112457 A1 HK 1112457A1
Authority
HK
Hong Kong
Prior art keywords
antagonists
substituted piperazines
piperazines
substituted
Prior art date
Application number
HK08101323.8A
Other languages
English (en)
Inventor
Eric J Gilbert
Michael W Miller
Jack D Scott
Andrew W Stamford
William J Greenlee
Jay Weinstein
Original Assignee
Intervet Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intervet Int Bv filed Critical Intervet Int Bv
Publication of HK1112457A1 publication Critical patent/HK1112457A1/xx

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    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Addiction (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HK08101323.8A 2004-12-03 2008-02-04 Substituted piperazines as cb1 antagonists HK1112457A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63310604P 2004-12-03 2004-12-03
PCT/US2005/043281 WO2006060461A1 (en) 2004-12-03 2005-12-01 Substituted piperazines as cb1 antagonists

Publications (1)

Publication Number Publication Date
HK1112457A1 true HK1112457A1 (en) 2008-09-05

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Application Number Title Priority Date Filing Date
HK08101323.8A HK1112457A1 (en) 2004-12-03 2008-02-04 Substituted piperazines as cb1 antagonists

Country Status (18)

Country Link
US (2) US7700597B2 (xx)
EP (1) EP1819684B1 (xx)
JP (2) JP5254620B2 (xx)
KR (1) KR101351209B1 (xx)
CN (3) CN101115726A (xx)
AR (1) AR054998A1 (xx)
AU (2) AU2005311930B9 (xx)
CA (1) CA2589483C (xx)
ES (1) ES2435790T3 (xx)
HK (1) HK1112457A1 (xx)
IL (1) IL183538A (xx)
MX (1) MX2007006695A (xx)
MY (1) MY144301A (xx)
NZ (1) NZ555320A (xx)
SG (1) SG163577A1 (xx)
TW (1) TWI343379B (xx)
WO (1) WO2006060461A1 (xx)
ZA (1) ZA200705002B (xx)

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WO2006060808A1 (en) * 2004-12-03 2006-06-08 Teva Pharmaceutical Industries Ltd. Ezetimibe polymorphs
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US20060234996A1 (en) * 2005-04-14 2006-10-19 Itai Adin Novel crystalline form of ezetimibe and processes for the preparation thereof
RU2415846C2 (ru) 2005-08-26 2011-04-10 Шионоги энд Ко., Лтд Производные, имеющие активность агонистов ppar-рецепторов
KR20070063592A (ko) * 2005-09-08 2007-06-19 테바 파마슈티컬 인더스트리즈 리미티드 에제티밉의 합성을 위한 중간체인(3ｒ,4ｓ)-4-((4-벤질옥시)페닐)-1-(4-플루오로페닐)-3-((ｓ)-3-(4-플루오로페닐)-3-히드록시프로필)-2-아제티디논의제조 방법
GB0523609D0 (en) * 2005-11-19 2005-12-28 Vernalis R&D Ltd Piperazine derivatives
WO2007070760A2 (en) 2005-12-15 2007-06-21 Boehringer Ingelheim International Gmbh Compounds which modulate the cb2 receptor
CA2637565A1 (en) 2006-01-18 2007-07-26 Schering Corporation Cannibinoid receptor modulators
AU2007275301A1 (en) * 2006-07-20 2008-01-24 Amgen Inc. Substituted azole aromatic heterocycles as inhibitors of 11-beta-HSD-1
CA2657247A1 (en) 2006-07-28 2008-01-31 Boehringer Ingelheim International Gmbh Compounds which modulate the cb2 receptor
WO2008017381A1 (de) 2006-08-08 2008-02-14 Sanofi-Aventis Arylaminoaryl-alkyl-substituierte imidazolidin-2,4-dione, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und ihre verwendung
EP2074084B1 (en) 2006-09-25 2013-08-28 Boehringer Ingelheim International GmbH Compounds which modulate the cb2 receptor
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CA2589483A1 (en) 2006-06-08
AU2009230816A1 (en) 2009-11-19
KR101351209B1 (ko) 2014-02-06
KR20070090176A (ko) 2007-09-05
AU2005311930B9 (en) 2009-09-10
US20060241121A1 (en) 2006-10-26
EP1819684B1 (en) 2013-08-07
CN102558075A (zh) 2012-07-11
AU2005311930A1 (en) 2006-06-08
US20100029607A1 (en) 2010-02-04
SG163577A1 (en) 2010-08-30
TW200626563A (en) 2006-08-01
JP5254620B2 (ja) 2013-08-07
CN102633730A (zh) 2012-08-15
IL183538A (en) 2013-05-30
TWI343379B (en) 2011-06-11
CN101115726A (zh) 2008-01-30
MY144301A (en) 2011-08-29
EP1819684A1 (en) 2007-08-22
IL183538A0 (en) 2007-09-20
AR054998A1 (es) 2007-08-01
US8236805B2 (en) 2012-08-07
CA2589483C (en) 2013-10-29
JP2011251994A (ja) 2011-12-15
JP2008521910A (ja) 2008-06-26
ES2435790T3 (es) 2013-12-23
AU2005311930B2 (en) 2009-08-06
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US7700597B2 (en) 2010-04-20
WO2006060461A1 (en) 2006-06-08

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