ZA200610255B - Activable particles, preparations and uses - Google Patents

Activable particles, preparations and uses

Info

Publication number
ZA200610255B
ZA200610255B ZA200610255A ZA200610255A ZA200610255B ZA 200610255 B ZA200610255 B ZA 200610255B ZA 200610255 A ZA200610255 A ZA 200610255A ZA 200610255 A ZA200610255 A ZA 200610255A ZA 200610255 B ZA200610255 B ZA 200610255B
Authority
ZA
South Africa
Prior art keywords
particles
relates
activable
preparations
health
Prior art date
Application number
ZA200610255A
Other languages
English (en)
Inventor
Levy Laurent
Hochepied Jean-Francois
Balencie Jeremy
Prasad Paras Nath
Bergey Earl Jim
Panak Eduouard Andre
Boussaha Abdel Kader
Original Assignee
Nanobiotix
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanobiotix filed Critical Nanobiotix
Publication of ZA200610255B publication Critical patent/ZA200610255B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/062Photodynamic therapy, i.e. excitation of an agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0052Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0409Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is not a halogenated organic compound
    • A61K49/0414Particles, beads, capsules or spheres
    • A61K49/0423Nanoparticles, nanobeads, nanospheres, nanocapsules, i.e. having a size or diameter smaller than 1 micrometer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0658Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0661Radiation therapy using light characterised by the wavelength of light used ultraviolet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092Details
    • A61N2005/1098Enhancing the effect of the particle by an injected agent or implanted device

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nanotechnology (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Paints Or Removers (AREA)
ZA200610255A 2004-05-10 2006-12-08 Activable particles, preparations and uses ZA200610255B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0405036A FR2869803B1 (fr) 2004-05-10 2004-05-10 Particules activables, preparation et utilisations

Publications (1)

Publication Number Publication Date
ZA200610255B true ZA200610255B (en) 2008-09-25

Family

ID=34945762

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200610255A ZA200610255B (en) 2004-05-10 2006-12-08 Activable particles, preparations and uses

Country Status (25)

Country Link
US (2) US9162079B2 (zh)
EP (1) EP1744789B1 (zh)
JP (1) JP5150251B2 (zh)
KR (2) KR101234334B1 (zh)
CN (1) CN100592921C (zh)
AT (1) ATE403444T1 (zh)
AU (1) AU2005251499B2 (zh)
BR (1) BRPI0510290B8 (zh)
CA (1) CA2564197C (zh)
CY (1) CY1108369T1 (zh)
DE (1) DE602005008731D1 (zh)
DK (1) DK1744789T3 (zh)
EA (1) EA010246B1 (zh)
ES (1) ES2312004T3 (zh)
FR (1) FR2869803B1 (zh)
HK (1) HK1099508A1 (zh)
HR (1) HRP20080534T3 (zh)
IL (1) IL178877A (zh)
MX (1) MXPA06013095A (zh)
PL (1) PL1744789T3 (zh)
PT (1) PT1744789E (zh)
RS (1) RS50615B (zh)
SI (1) SI1744789T1 (zh)
WO (1) WO2005120590A1 (zh)
ZA (1) ZA200610255B (zh)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2867180B1 (fr) 2004-03-02 2006-06-16 Univ Claude Bernard Lyon Nanoparticules hybrides comprenant un coeur de ln203 porteuses de ligands biologiques et leur procede de preparation
FR2869803B1 (fr) 2004-05-10 2006-07-28 Nanobiotix Sarl Particules activables, preparation et utilisations
FR2877571B1 (fr) * 2004-11-05 2007-04-13 Nanobiotix Sarl Nanoparticules pourvues d'un element de ciblage intracellulaire, preparation et utilisations
CA2587392C (en) * 2004-11-15 2013-02-12 Australian Nuclear Science & Technology Organisation Solid particles from controlled destabilisation of microemulsions
US20070218049A1 (en) * 2006-02-02 2007-09-20 Wei Chen Nanoparticle based photodynamic therapy and methods of making and using same
US20090130050A1 (en) * 2006-03-24 2009-05-21 Toto Ltd. Titanium Oxide Composite Particles, Dispersion Liquid Thereof, and Process for Producing Them
EP1852107A1 (en) * 2006-04-19 2007-11-07 Nanobiotix Magnetic nanoparticles compositions and uses thereof
EP1920784A1 (en) * 2006-11-13 2008-05-14 Koninklijke Philips Electronics N.V. Radiation sensitizers in ionizing radiation therapy and imaging
US9488916B2 (en) 2007-04-08 2016-11-08 Immunolight, Llc. Interior energy-activation of photo-reactive species inside a medium or body
US9358292B2 (en) * 2007-04-08 2016-06-07 Immunolight, Llc Methods and systems for treating cell proliferation disorders
US8951561B2 (en) 2007-08-06 2015-02-10 Duke University Methods and systems for treating cell proliferation disorders using plasmonics enhanced photospectral therapy (PEPST) and exciton-plasmon enhanced phototherapy (EPEP)
FR2922106B1 (fr) * 2007-10-16 2011-07-01 Univ Claude Bernard Lyon Utilisation de nanoparticules a base de lanthanides comme agents radiosensibilisants.
US20090104113A1 (en) * 2007-10-18 2009-04-23 Searete Llc Ionizing-radiation-responsive compositions, methods, and systems
GB2453860B (en) * 2007-10-18 2011-03-16 Searete Llc Ionizing-radiation-responsive compositions,methods and systems
US8227204B2 (en) * 2007-10-18 2012-07-24 The Invention Science Fund I, Llc Ionizing-radiation-responsive compositions, methods, and systems
US9557635B2 (en) * 2007-10-18 2017-01-31 Gearbox, Llc Ionizing-radiation-responsive compositions, methods, and systems
US8529426B2 (en) * 2007-10-18 2013-09-10 The Invention Science Fund I Llc Ionizing-radiation-responsive compositions, methods, and systems
US8168958B2 (en) * 2007-10-18 2012-05-01 The Invention Science Fund I, Llc Ionizing-radiation-responsive compositions, methods, and systems
US8684898B2 (en) * 2007-10-18 2014-04-01 The Invention Science Fund I Llc Ionizing-radiation-responsive compositions, methods, and systems
US8164074B2 (en) * 2007-10-18 2012-04-24 The Invention Science Fund I, Llc Ionizing-radiation-responsive compositions, methods, and systems
US9907976B2 (en) 2011-07-08 2018-03-06 Immunolight, Llc Phosphors and scintillators for light stimulation within a medium
CL2009000560A1 (es) 2008-03-11 2010-02-19 Univ Duke Un metodo para endurecer un medio endurecible por radiacion que comprende colocar una composicion dentro de un objeto para ser endurecido, la aplicacion de al menos uno elegido entre rayos x, rayos gama o haz de electrones a traves del objeto y dentro de la composicion.
CA3095369C (en) * 2008-04-04 2023-09-26 Immunolight, Llc Non-invasive systems and methods for in-situ photobiomodulation
EP2130553A1 (en) * 2008-06-05 2009-12-09 Nanobiotix Inorganic nanoparticles of high density to destroy cells in-vivo
US8770203B2 (en) * 2008-07-14 2014-07-08 Immunolight, Llc. Advanced methods and systems for treating cell proliferation disorders
EP2328620A2 (en) 2008-07-31 2011-06-08 Alma Mater Studiorum - Università di Bologna Active particles for bio-analytical applications and methods for their preparation
JP5908396B2 (ja) 2009-04-21 2016-04-26 イミュノライト・エルエルシー insituフォトバイオモジュレーションのための、非侵襲的エネルギーアップコンバージョン方法およびシステム
CN107149689A (zh) 2009-11-10 2017-09-12 免疫之光有限责任公司 对可辐射固化介质进行固化的系统和产生光的方法
GB0921596D0 (en) 2009-12-09 2010-01-27 Isis Innovation Particles for the treatment of cancer in combination with radiotherapy
SI2567257T1 (sl) 2010-05-06 2021-09-30 Immunolight, Llc. Lepilni vezivni sestavek in postopek uporabe
US9572880B2 (en) 2010-08-27 2017-02-21 Sienna Biopharmaceuticals, Inc. Ultrasound delivery of nanoparticles
PL3210591T3 (pl) 2010-08-27 2019-08-30 Sienna Biopharmaceuticals, Inc. Kompozycje i sposoby do termomodulacji celowanej
US9116246B2 (en) * 2011-04-07 2015-08-25 Stc.Unm Thermal neutron detectors based on gadolinium-containing nanoscintillators
JPWO2012153820A1 (ja) * 2011-05-12 2014-07-31 コニカミノルタ株式会社 X線吸収蛍光ナノ粒子
WO2013009701A2 (en) 2011-07-08 2013-01-17 The University Of North Carolina At Chapel Hill Metal bisphosphonate nanoparticles for anti-cancer therapy and imaging and for treating bone disorders
WO2013035739A1 (ja) * 2011-09-05 2013-03-14 株式会社Ihi 温熱治療用材料、温熱治療用システム及び温熱治療方法
AU2012351537B2 (en) 2011-12-16 2017-03-02 Nanobiotix Nanoparticles comprising metallic and hafnium oxide materials, preparation and uses thereof
ES2629903T3 (es) 2012-10-11 2017-08-16 Nanocomposix, Inc. Composiciones y método de nanoplacas de plata
WO2014202723A1 (en) * 2013-06-20 2014-12-24 Nanobiotix Compositions and methods for use in medical diagnosis
JP6484229B2 (ja) * 2013-06-20 2019-03-13 ナノビオティックスNanobiotix 腫瘍学に使用するための組成物および方法
FR3018451A1 (fr) * 2014-03-13 2015-09-18 Chromalys Nanoparticules pour leur utilisation dans la detection de tumeurs mobiles
US10780164B2 (en) * 2014-04-03 2020-09-22 The Governing Council Of The University Of Toronto Multifunctional nanoparticle compositions and uses thereof
JP6731404B2 (ja) 2014-10-14 2020-07-29 ザ ユニバーシティ オブ シカゴThe University Of Chicago 光線力学療法、x線誘起光線力学療法、放射線療法、化学療法、免疫療法、及びこれらの任意の組み合わせのためのナノ粒子
US10806694B2 (en) 2014-10-14 2020-10-20 The University Of Chicago Nanoparticles for photodynamic therapy, X-ray induced photodynamic therapy, radiotherapy, radiodynamic therapy, chemotherapy, immunotherapy, and any combination thereof
EP3242670B1 (en) * 2015-01-08 2020-06-24 Purdue Research Foundation Non-toxic formulations of radio-luminescent nanoparticles for use as cancer radio-sensitizing agents
WO2016189125A1 (en) 2015-05-28 2016-12-01 Nanobiotix Nanoparticles for use as a therapeutic vaccine
US9770688B2 (en) * 2015-10-22 2017-09-26 King Fahd University Of Petroleum And Minerals Si—Y nanocomposite membrane and methods of making and use thereof
WO2017201528A1 (en) 2016-05-20 2017-11-23 The University Of Chicago Nanoparticles for chemotherapy, targeted therapy, photodynamic therapy, immunotherapy, and any combination thereof
AU2017371069A1 (en) 2016-12-08 2019-06-20 Centre National De La Recherche Scientifique Bismuth-gadolinium nanoparticles
US10283476B2 (en) 2017-03-15 2019-05-07 Immunolight, Llc. Adhesive bonding composition and electronic components prepared from the same
EP3638367A4 (en) 2017-08-02 2021-07-21 The University of Chicago NANOMETRIC ORGANOMETALLIC AND NANOPLAQUE ORGANOMETALLIC LAYERS FOR X-RAY INDUCED PHOTODYNAMIC THERAPY, RADIOTHERAPY, RADIODYNAMIC THERAPY, CHEMOTHERAPY, IMMUNOTHERAPY, AND ANY COMBINATION OF THESE
US11191836B2 (en) 2018-06-01 2021-12-07 Tae Life Sciences, Llc Biodegradable nanocarrier(s) (BPMOs) for neutron capture therapy and methods thereof
EP4255488A1 (en) * 2020-12-01 2023-10-11 Nanobiotix Porous, high-z and carbon-free particles as radioenhancers
CN112655715A (zh) * 2020-12-25 2021-04-16 杭州甜蜜按钮科技有限公司 一种哺乳期羊舍专用消毒剂的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985173A (en) * 1997-11-18 1999-11-16 Gray; Henry F. Phosphors having a semiconductor host surrounded by a shell
JP3490015B2 (ja) * 1999-03-11 2004-01-26 関西ティー・エル・オー株式会社 化学的耐久性に優れた放射性微小球及びその製造方法
AU2001236798B2 (en) * 2000-02-08 2004-11-04 Rice University Optically-active nanoparticles for use in therapeutic and diagnostic methods
AU2001258358B2 (en) * 2000-05-05 2005-10-27 Bayer Intellectual Property Gmbh Doped nanoparticles as biolabels
US20020127224A1 (en) * 2001-03-02 2002-09-12 James Chen Use of photoluminescent nanoparticles for photodynamic therapy
CN1893976A (zh) * 2003-12-17 2007-01-10 皇家飞利浦电子股份有限公司 使用uv发射纳米微粒的放射治疗和医学成像
WO2005107818A2 (en) * 2004-04-30 2005-11-17 University Of Florida Nanoparticles and their use for multifunctional bioimaging
FR2869803B1 (fr) 2004-05-10 2006-07-28 Nanobiotix Sarl Particules activables, preparation et utilisations
US20070218049A1 (en) * 2006-02-02 2007-09-20 Wei Chen Nanoparticle based photodynamic therapy and methods of making and using same

Also Published As

Publication number Publication date
JP2007536356A (ja) 2007-12-13
BRPI0510290B1 (pt) 2021-06-01
ES2312004T3 (es) 2009-02-16
US9433800B2 (en) 2016-09-06
BRPI0510290A (pt) 2007-10-30
KR20070014172A (ko) 2007-01-31
PT1744789E (pt) 2008-11-04
US9162079B2 (en) 2015-10-20
AU2005251499B2 (en) 2010-06-10
CA2564197A1 (fr) 2005-12-22
US20150238775A1 (en) 2015-08-27
IL178877A (en) 2010-12-30
EP1744789B1 (fr) 2008-08-06
FR2869803A1 (fr) 2005-11-11
CA2564197C (fr) 2013-05-07
WO2005120590A1 (fr) 2005-12-22
AU2005251499A1 (en) 2005-12-22
DK1744789T3 (da) 2008-12-08
SI1744789T1 (sl) 2008-10-31
HRP20080534T3 (en) 2008-11-30
KR20120123731A (ko) 2012-11-09
PL1744789T3 (pl) 2009-01-30
EA010246B1 (ru) 2008-06-30
CN1950111A (zh) 2007-04-18
IL178877A0 (en) 2007-03-08
ATE403444T1 (de) 2008-08-15
US20070217996A1 (en) 2007-09-20
CY1108369T1 (el) 2014-02-12
BRPI0510290B8 (pt) 2021-10-19
CN100592921C (zh) 2010-03-03
JP5150251B2 (ja) 2013-02-20
MXPA06013095A (es) 2007-04-27
BRPI0510290A8 (pt) 2019-01-02
RS50615B (sr) 2010-06-30
HK1099508A1 (en) 2007-08-17
DE602005008731D1 (de) 2008-09-18
FR2869803B1 (fr) 2006-07-28
KR101234334B1 (ko) 2013-02-18
EA200602077A1 (ru) 2007-04-27
EP1744789A1 (fr) 2007-01-24

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