ATE455463T1 - Verfahren zur herstellung gefriergetrockneter blutplättchen, gefriergetrocknete blutplättchen enthaltende zusammensetzungen und verwendungsverfahren - Google Patents

Verfahren zur herstellung gefriergetrockneter blutplättchen, gefriergetrocknete blutplättchen enthaltende zusammensetzungen und verwendungsverfahren

Info

Publication number
ATE455463T1
ATE455463T1 AT05784165T AT05784165T ATE455463T1 AT E455463 T1 ATE455463 T1 AT E455463T1 AT 05784165 T AT05784165 T AT 05784165T AT 05784165 T AT05784165 T AT 05784165T AT E455463 T1 ATE455463 T1 AT E455463T1
Authority
AT
Austria
Prior art keywords
freeze
dried blood
blood plates
methods
compositions containing
Prior art date
Application number
AT05784165T
Other languages
English (en)
Inventor
David Ho
Cindy Orser
Alan Rudolph
Keith Moskowitz
Joshua Dee
Original Assignee
Cellphire Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/152,774 external-priority patent/US20060035383A1/en
Priority claimed from US11/197,310 external-priority patent/US20060051731A1/en
Application filed by Cellphire Inc filed Critical Cellphire Inc
Application granted granted Critical
Publication of ATE455463T1 publication Critical patent/ATE455463T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0278—Physical preservation processes
    • A01N1/0284—Temperature processes, i.e. using a designated change in temperature over time
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/19—Platelets; Megacaryocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT05784165T 2004-08-12 2005-08-12 Verfahren zur herstellung gefriergetrockneter blutplättchen, gefriergetrocknete blutplättchen enthaltende zusammensetzungen und verwendungsverfahren ATE455463T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US60083804P 2004-08-12 2004-08-12
US61993004P 2004-10-20 2004-10-20
US11/152,774 US20060035383A1 (en) 2004-08-12 2005-06-15 Dry platelet preparations for use in diagnostics
US11/197,310 US20060051731A1 (en) 2004-08-12 2005-08-05 Processes for preparing lyophilized platelets
PCT/US2005/028559 WO2006020773A2 (en) 2004-08-12 2005-08-12 Methods for preparing freeze-dried platelets, compositions comprising freeze-dried platelets, and methods of use

Publications (1)

Publication Number Publication Date
ATE455463T1 true ATE455463T1 (de) 2010-02-15

Family

ID=35908143

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05784165T ATE455463T1 (de) 2004-08-12 2005-08-12 Verfahren zur herstellung gefriergetrockneter blutplättchen, gefriergetrocknete blutplättchen enthaltende zusammensetzungen und verwendungsverfahren

Country Status (10)

Country Link
US (1) US8486617B2 (de)
EP (1) EP1784639B1 (de)
JP (1) JP5138372B2 (de)
CN (1) CN101072506B (de)
AT (1) ATE455463T1 (de)
AU (1) AU2005272821B2 (de)
CA (1) CA2577068C (de)
DE (1) DE602005019064D1 (de)
NZ (1) NZ553389A (de)
WO (1) WO2006020773A2 (de)

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US8058064B2 (en) * 2006-10-04 2011-11-15 The University Of Tokyo Sac-like structure enclosing hematopoietic progenitor cells produced from ES cells and method for preparing blood cells
US8372343B2 (en) * 2007-12-07 2013-02-12 Sheldon Goldstein Multiple coagulation test cartridge and method of using same
WO2010022202A1 (en) * 2008-08-20 2010-02-25 Bio/Data Corporation Kinetic biologic activity assays and kinetic von willebrand assay
EP2555613A1 (de) * 2010-04-08 2013-02-13 INSERM - Institut National de la Santé et de la Recherche Médicale Zeodrationsverfahren zur konservierung von blutplättchen
WO2012018638A2 (en) 2010-07-26 2012-02-09 Biomatrica, Inc. Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures
US9845489B2 (en) 2010-07-26 2017-12-19 Biomatrica, Inc. Compositions for stabilizing DNA, RNA and proteins in saliva and other biological samples during shipping and storage at ambient temperatures
CN101957364A (zh) * 2010-09-19 2011-01-26 李勇 冻干型血小板抗原谱细胞的制备方法
WO2012098358A1 (en) * 2011-01-20 2012-07-26 Biopharma Technology Ltd Freeze drying method
GB201101002D0 (en) * 2011-01-20 2011-03-09 Biopharma Technology Ltd Freeze drying method
EP2508892A1 (de) 2011-04-04 2012-10-10 Siemens Healthcare Diagnostics Products GmbH Kontrollen und Kit für Thrombozytenaktivitätsteste
CN102327288B (zh) * 2011-10-17 2012-11-14 济南环肽医药科技有限公司 一种注射用血小板冻干粉制剂及其制备方法
WO2014100755A2 (en) 2012-12-20 2014-06-26 Biomatrica, Inc. Formulations and methods for stabilizing pcr reagents
JP6448615B2 (ja) * 2013-03-15 2019-01-09 クック・バイオテック・インコーポレイテッドＣｏｏｋ Ｂｉｏｔｅｃｈ Ｉｎｃｏｒｐｏｒａｔｅｄ Ｅｃｍ移植組成物および方法
AU2013204728B2 (en) * 2013-03-15 2016-09-15 Baxalta GmbH Methods for treating bleeding disorders using a platelet subpopulation
TW201446253A (zh) * 2013-06-07 2014-12-16 Chang Gung Medical Foundation Lin Kou Chang Gung Memorial Hospital 非凝集預活變形血小板之應用及其藥劑
EP3656215B1 (de) * 2014-06-10 2021-08-04 Biomatrica, INC. Stabilisierung von thrombozyten bei umgebungstemperatur
AU2015301303B2 (en) 2014-08-07 2021-07-15 The General Hospital Corporation Stabilization of whole blood samples
MX2017008823A (es) * 2014-12-31 2017-11-17 Anthrogenesis Corp Metodos para aislamiento de plaquetas.
WO2016141325A1 (en) 2015-03-04 2016-09-09 University Of Rochester Systemic and topical application of platelet microparticles to treat bleeding in trauma patients
CA2988610A1 (en) * 2015-06-10 2016-12-15 Cellphire, Inc. Composition and methods for treatment of loss of fluids leading to hypotension and/or hypovolemia
WO2017040238A1 (en) * 2015-08-28 2017-03-09 Cellphire, Inc. Products and methods using a platelet-derived hemostatic agent for controlling bleeding and improving healing
KR20230145258A (ko) 2015-12-08 2023-10-17 바이오매트리카 인코포레이티드 적혈구 침강 속도의 감소
US20190041379A1 (en) * 2016-02-10 2019-02-07 Sony Corporation Sample for measurement of electric characteristics, electric characteristic measuring apparatus, and electric characteristic measuring method
AU2016431615A1 (en) * 2016-12-08 2019-06-20 Cellphire, Inc. Compositions and methods for treatment of loss of fluids leading to hypotension and/or hypovolemia
JP6854351B2 (ja) * 2016-12-21 2021-04-07 スン・チュン・チンＣｈｕｎｇ Ｃｈｉｎ ＳＵＮ 血漿タンパク質活性保存のための新規な方法
EP3681518A4 (de) * 2017-09-13 2021-06-23 Cellphire Inc. Blutplättchenpräparate aus hunden
CN107998375B (zh) * 2017-12-14 2021-11-05 广东医科大学 一种多肽在预防或治疗血栓性疾病或脑缺血再灌注损伤相关疾病中的应用
US20200224164A1 (en) * 2018-11-30 2020-07-16 Cellphire, Inc. Platelets as delivery agents
EP3886879A4 (de) 2018-11-30 2022-12-07 Cellphire Inc. Thrombozyten als freisetzungsmittel
US20210180016A1 (en) * 2019-11-27 2021-06-17 Cellphire, Inc. PLATELETS LOADED WITH mRNA
WO2020186193A1 (en) * 2019-03-13 2020-09-17 Cellphire, Inc. Canine blood platelet preparations
US10429377B1 (en) 2019-03-15 2019-10-01 Coagulation Sciences Llc Coagulation test device, system, and method of use
WO2020227149A1 (en) * 2019-05-03 2020-11-12 Cellphire, Inc. Materials and methods for producing blood products
CA3147618A1 (en) * 2019-07-17 2021-01-21 Cellphire, Inc. Use of platelets in treating infections
AU2020333666A1 (en) * 2019-08-16 2022-03-31 Cellphire, Inc. Thrombosomes as an anticoagulant reversal agent
EP4013496A4 (de) * 2019-08-16 2023-10-18 Cellphire Inc. Thrombosomen als mittel zur aufhebung der thrombozytenaggregationshemmenden wirkung
CN110585240B (zh) * 2019-10-10 2021-10-29 石开生物科技(广州)有限公司 一种含再生因子的冻干制剂及其制备方法和应用
WO2021158622A1 (en) 2020-02-04 2021-08-12 Cellphire, Inc. Anti-fibrinolytic loaded platelets
WO2021232015A1 (en) 2020-05-15 2021-11-18 Cellphire, Inc. Platelet derived extracellular vesicles
CN113156144A (zh) * 2021-01-29 2021-07-23 郑州普湾医疗技术有限公司 一种血小板聚集功能花生四烯酸杯检测试剂及其制备方法
WO2022178191A1 (en) 2021-02-17 2022-08-25 Cellphire, Inc. Freeze-dried platelet derivative compositions for treating anticoagulant-induced coagulopathy
WO2022178177A1 (en) 2021-02-17 2022-08-25 Cellphire, Inc. Freeze-dried platelet derivative compositions for treating antiplatelet-induced coagulopathy
EP4086634A1 (de) * 2021-05-06 2022-11-09 Eberhard Karls Universität Tübingen Medizinische Fakultät Verfahren zur diagnose einer prädisposition eines lebewesens zur entwicklung von thrombozytopenie
WO2023081804A1 (en) 2021-11-04 2023-05-11 Cellphire, Inc. Platelet derivative compositions, and methods of making and using such compositions
WO2023220694A1 (en) 2022-05-12 2023-11-16 Cellphire, Inc. Mri-agent loaded platelet compositions and methods of preparing and using the same
WO2023220739A1 (en) 2022-05-12 2023-11-16 Cellphire, Inc. Platelet derivative compositions for use in subjects afflicted with hermansky pudlak syndrome or bernard soulier syndrome
CN117180441A (zh) * 2023-10-11 2023-12-08 北京朴汇细胞生物科技有限公司 一种血小板脱水干燥保护剂、血小板脱水干燥制剂及其制备方法

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Also Published As

Publication number Publication date
WO2006020773A2 (en) 2006-02-23
DE602005019064D1 (de) 2010-03-11
JP5138372B2 (ja) 2013-02-06
EP1784639A2 (de) 2007-05-16
CN101072506A (zh) 2007-11-14
EP1784639B1 (de) 2010-01-20
US20070243178A1 (en) 2007-10-18
NZ553389A (en) 2009-10-30
CN101072506B (zh) 2010-05-12
CA2577068A1 (en) 2006-02-23
WO2006020773A3 (en) 2007-07-12
CA2577068C (en) 2016-05-17
JP2008509924A (ja) 2008-04-03
AU2005272821B2 (en) 2010-09-09
EP1784639A4 (de) 2008-05-07
AU2005272821A1 (en) 2006-02-23
US8486617B2 (en) 2013-07-16

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