NO20082425L - Formuleringer omfattende jorumycin-, reni-eramycin-, safracin- eller saframycin-relaterte forbindelser for behandling av proliferative sykdommer - Google Patents

Formuleringer omfattende jorumycin-, reni-eramycin-, safracin- eller saframycin-relaterte forbindelser for behandling av proliferative sykdommer

Info

Publication number
NO20082425L
NO20082425L NO20082425A NO20082425A NO20082425L NO 20082425 L NO20082425 L NO 20082425L NO 20082425 A NO20082425 A NO 20082425A NO 20082425 A NO20082425 A NO 20082425A NO 20082425 L NO20082425 L NO 20082425L
Authority
NO
Norway
Prior art keywords
formulations
jorumycin
safracin
saframycin
related compounds
Prior art date
Application number
NO20082425A
Other languages
English (en)
Other versions
NO341057B1 (no
Inventor
Salve Pilar Calvo
Maria Tobio Barreira
Original Assignee
Pharma Mar Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharma Mar Sa filed Critical Pharma Mar Sa
Publication of NO20082425L publication Critical patent/NO20082425L/no
Publication of NO341057B1 publication Critical patent/NO341057B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Jorumycin-, renieramycin-, safracin- og saframycinrelaterte forbindelsesformuleringer, fremgangsmåter for fremstilling av disse, fremstillingsartikler og sett med slike- formuleringer, og metoder for behandling av proliferative sykdommer med de samme formuleringer er tilveiebrakt.
NO20082425A 2005-10-31 2008-05-30 Farmasøytisk sammensetning, som omfatter et disakkarid og en jorumycin-, renieramycin-, safracin- eller saframycin-beslektet forbindelse, fremgangsmåte for fremstilling av en ampulle inneholdende en lyofilisert formulering derav, fremgangsmåte for redusering av dannelsen av urenheter i formuleringen, fremgangsmåte for fremstilling av en løsning derav for intravenøs infusjon, anvendelse derav ved fremstilling av et medikament for behandling av kreft. NO341057B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0522082.7A GB0522082D0 (en) 2005-10-31 2005-10-31 Formulations
PCT/GB2006/050362 WO2007052076A2 (en) 2005-10-31 2006-10-30 Formulations comprising jorumycin-, reni eramycin-, safracin- or saframycin-related compounds for treating proliferative diseases

Publications (2)

Publication Number Publication Date
NO20082425L true NO20082425L (no) 2008-07-25
NO341057B1 NO341057B1 (no) 2017-08-14

Family

ID=35515969

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20082425A NO341057B1 (no) 2005-10-31 2008-05-30 Farmasøytisk sammensetning, som omfatter et disakkarid og en jorumycin-, renieramycin-, safracin- eller saframycin-beslektet forbindelse, fremgangsmåte for fremstilling av en ampulle inneholdende en lyofilisert formulering derav, fremgangsmåte for redusering av dannelsen av urenheter i formuleringen, fremgangsmåte for fremstilling av en løsning derav for intravenøs infusjon, anvendelse derav ved fremstilling av et medikament for behandling av kreft.

Country Status (23)

Country Link
US (1) US9192568B2 (no)
EP (1) EP1968592B1 (no)
JP (1) JP5197373B2 (no)
KR (1) KR101434230B1 (no)
CN (1) CN101300011B (no)
AT (1) ATE549023T1 (no)
AU (1) AU2006310260C1 (no)
CA (1) CA2625096C (no)
DK (1) DK1968592T3 (no)
ES (1) ES2383967T3 (no)
GB (1) GB0522082D0 (no)
HR (1) HRP20120478T1 (no)
IL (1) IL190774A (no)
NO (1) NO341057B1 (no)
NZ (1) NZ567291A (no)
PL (1) PL1968592T3 (no)
PT (1) PT1968592E (no)
RS (1) RS52312B (no)
RU (1) RU2429845C2 (no)
SI (1) SI1968592T1 (no)
UA (1) UA97629C2 (no)
WO (1) WO2007052076A2 (no)
ZA (1) ZA200803420B (no)

Families Citing this family (10)

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GB0117402D0 (en) * 2001-07-17 2001-09-05 Pharma Mar Sa New antitumoral derivatives of et-743
GB0708691D0 (en) * 2007-05-04 2007-06-13 Pharma Mar Sa Anticancer treatments a
KR20110025178A (ko) * 2008-05-16 2011-03-09 파르마 마르 에스.에이. Ｐｍ00104 및 다른 항종양제를 이용한 복합 치료법
CN102065865B (zh) * 2008-05-16 2013-03-20 马尔药品公司 多发性骨髓瘤治疗
WO2011048210A1 (en) 2009-10-22 2011-04-28 Pharma Mar, S.A. PDGFR-α AS RESPONSE MARKER FOR PM00104 TREATMENT
CA2833500C (en) * 2011-04-28 2019-01-08 Oncopeptides Ab Lyophilized preparation of cytotoxic dipeptides
WO2014065751A1 (en) 2012-10-26 2014-05-01 Oncopeptides Ab Lyophilized preparations of melphalan flufenamide
JOP20190254A1 (ar) 2017-04-27 2019-10-27 Pharma Mar Sa مركبات مضادة للأورام
US10526334B2 (en) 2017-07-19 2020-01-07 California Institute Of Technology Methods for preparing bis-tetrahydroisoquinoline-containing compounds
US20240197726A1 (en) * 2021-03-03 2024-06-20 The University Of Tokyo Novel tetrahydroisoquinoline alkaloid compound containing macrocycle

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PT1067933E (pt) 1998-04-06 2007-11-15 Univ Illinois Ecteinascidinas semi-sintéticas
CZ302168B6 (cs) 1998-05-11 2010-11-24 Pharma Mar, S. A. Metabolity ecteinascidinu 743
JP2000081438A (ja) 1998-06-25 2000-03-21 Sekisui Chem Co Ltd 被験者の癌化学療法による免疫機能低下の測定方法
US6124292A (en) * 1998-09-30 2000-09-26 President And Fellows Of Harvard College Synthetic analogs of ecteinascidin-743
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Also Published As

Publication number Publication date
IL190774A0 (en) 2008-11-03
AU2006310260B2 (en) 2012-08-09
KR20080064959A (ko) 2008-07-10
AU2006310260A1 (en) 2007-05-10
KR101434230B1 (ko) 2014-08-26
WO2007052076A2 (en) 2007-05-10
GB0522082D0 (en) 2005-12-07
HK1122743A1 (en) 2009-07-17
HRP20120478T1 (hr) 2012-07-31
RU2429845C2 (ru) 2011-09-27
JP2009513618A (ja) 2009-04-02
CA2625096C (en) 2015-11-24
JP5197373B2 (ja) 2013-05-15
ES2383967T3 (es) 2012-06-27
UA97629C2 (ru) 2012-03-12
NO341057B1 (no) 2017-08-14
RU2008121716A (ru) 2009-12-10
US9192568B2 (en) 2015-11-24
SI1968592T1 (sl) 2012-10-30
IL190774A (en) 2013-11-28
PL1968592T3 (pl) 2012-08-31
ATE549023T1 (de) 2012-03-15
WO2007052076A3 (en) 2008-03-20
DK1968592T3 (da) 2012-07-02
AU2006310260C1 (en) 2013-09-19
CA2625096A1 (en) 2007-05-10
US20090076016A1 (en) 2009-03-19
CN101300011B (zh) 2011-12-28
PT1968592E (pt) 2012-06-18
EP1968592B1 (en) 2012-03-14
ZA200803420B (en) 2009-10-28
CN101300011A (zh) 2008-11-05
EP1968592A2 (en) 2008-09-17
RS52312B (sr) 2012-12-31
NZ567291A (en) 2011-04-29

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