UA97629C2 - Фармацевтическая композиция, имеющая противоопухолевую активность, и способы - Google Patents

Фармацевтическая композиция, имеющая противоопухолевую активность, и способы

Info

Publication number
UA97629C2
UA97629C2 UAA200807478A UAA200807478A UA97629C2 UA 97629 C2 UA97629 C2 UA 97629C2 UA A200807478 A UAA200807478 A UA A200807478A UA A200807478 A UAA200807478 A UA A200807478A UA 97629 C2 UA97629 C2 UA 97629C2
Authority
UA
Ukraine
Prior art keywords
methods
pharmaceutical formulation
antitumor activity
formulation exhibiting
exhibiting antitumor
Prior art date
Application number
UAA200807478A
Other languages
English (en)
Ukrainian (uk)
Inventor
Сальве Пилар Кальво
Баррейра Мария Тобио
Original Assignee
Фарма Мар, С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Фарма Мар, С.А. filed Critical Фарма Мар, С.А.
Publication of UA97629C2 publication Critical patent/UA97629C2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Изобретение относится к области фармацевтики и медицины и касается фармацевтической композиции, имеющей противоопухолевую активность, содержащей соединение, родственное джорумицину, рениерамицину, сафрацину и сафрамицину, и дисахарид. Изобретение также касается флакона, заполненного лиофилизированной композицией, способа получения раствора для внутривенной инфузии и способа лечения рака.
UAA200807478A 2005-10-31 2006-10-30 Фармацевтическая композиция, имеющая противоопухолевую активность, и способы UA97629C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0522082.7A GB0522082D0 (en) 2005-10-31 2005-10-31 Formulations
PCT/GB2006/050362 WO2007052076A2 (en) 2005-10-31 2006-10-30 Formulations comprising jorumycin-, reni eramycin-, safracin- or saframycin-related compounds for treating proliferative diseases

Publications (1)

Publication Number Publication Date
UA97629C2 true UA97629C2 (ru) 2012-03-12

Family

ID=35515969

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200807478A UA97629C2 (ru) 2005-10-31 2006-10-30 Фармацевтическая композиция, имеющая противоопухолевую активность, и способы

Country Status (24)

Country Link
US (1) US9192568B2 (ru)
EP (1) EP1968592B1 (ru)
JP (1) JP5197373B2 (ru)
KR (1) KR101434230B1 (ru)
CN (1) CN101300011B (ru)
AT (1) ATE549023T1 (ru)
AU (1) AU2006310260C1 (ru)
CA (1) CA2625096C (ru)
DK (1) DK1968592T3 (ru)
ES (1) ES2383967T3 (ru)
GB (1) GB0522082D0 (ru)
HK (1) HK1122743A1 (ru)
HR (1) HRP20120478T1 (ru)
IL (1) IL190774A (ru)
NO (1) NO341057B1 (ru)
NZ (1) NZ567291A (ru)
PL (1) PL1968592T3 (ru)
PT (1) PT1968592E (ru)
RS (1) RS52312B (ru)
RU (1) RU2429845C2 (ru)
SI (1) SI1968592T1 (ru)
UA (1) UA97629C2 (ru)
WO (1) WO2007052076A2 (ru)
ZA (1) ZA200803420B (ru)

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GB0708691D0 (en) * 2007-05-04 2007-06-13 Pharma Mar Sa Anticancer treatments a
NZ589269A (en) * 2008-05-16 2013-03-28 Pharma Mar Sa Combination therapy with an antitumor alkaloid
KR20110028454A (ko) * 2008-05-16 2011-03-18 파르마 마르 에스.에이. 다발성 골수종 치료법
WO2011048210A1 (en) 2009-10-22 2011-04-28 Pharma Mar, S.A. PDGFR-α AS RESPONSE MARKER FOR PM00104 TREATMENT
WO2012146625A1 (en) * 2011-04-28 2012-11-01 Oncopeptides Ab Lyophilized preparation of cytotoxic dipeptides
EP2928463B1 (en) 2012-10-26 2019-11-20 Oncopeptides AB Lyophilized preparations of melphalan flufenamide
JOP20190254A1 (ar) 2017-04-27 2019-10-27 Pharma Mar Sa مركبات مضادة للأورام
US10526334B2 (en) 2017-07-19 2020-01-07 California Institute Of Technology Methods for preparing bis-tetrahydroisoquinoline-containing compounds
JPWO2022186221A1 (ru) * 2021-03-03 2022-09-09

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Also Published As

Publication number Publication date
IL190774A0 (en) 2008-11-03
EP1968592A2 (en) 2008-09-17
PL1968592T3 (pl) 2012-08-31
SI1968592T1 (sl) 2012-10-30
CA2625096C (en) 2015-11-24
AU2006310260C1 (en) 2013-09-19
AU2006310260A1 (en) 2007-05-10
DK1968592T3 (da) 2012-07-02
WO2007052076A3 (en) 2008-03-20
US20090076016A1 (en) 2009-03-19
ES2383967T3 (es) 2012-06-27
CN101300011A (zh) 2008-11-05
NZ567291A (en) 2011-04-29
NO341057B1 (no) 2017-08-14
ZA200803420B (en) 2009-10-28
NO20082425L (no) 2008-07-25
PT1968592E (pt) 2012-06-18
US9192568B2 (en) 2015-11-24
CA2625096A1 (en) 2007-05-10
WO2007052076A2 (en) 2007-05-10
GB0522082D0 (en) 2005-12-07
IL190774A (en) 2013-11-28
CN101300011B (zh) 2011-12-28
JP5197373B2 (ja) 2013-05-15
HK1122743A1 (en) 2009-07-17
KR101434230B1 (ko) 2014-08-26
EP1968592B1 (en) 2012-03-14
JP2009513618A (ja) 2009-04-02
ATE549023T1 (de) 2012-03-15
RS52312B (en) 2012-12-31
RU2008121716A (ru) 2009-12-10
RU2429845C2 (ru) 2011-09-27
KR20080064959A (ko) 2008-07-10
HRP20120478T1 (hr) 2012-07-31
AU2006310260B2 (en) 2012-08-09

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