DE602006018057D1 - Substituierte chinolone und verwendungsverfahren - Google Patents
Substituierte chinolone und verwendungsverfahrenInfo
- Publication number
- DE602006018057D1 DE602006018057D1 DE602006018057T DE602006018057T DE602006018057D1 DE 602006018057 D1 DE602006018057 D1 DE 602006018057D1 DE 602006018057 T DE602006018057 T DE 602006018057T DE 602006018057 T DE602006018057 T DE 602006018057T DE 602006018057 D1 DE602006018057 D1 DE 602006018057D1
- Authority
- DE
- Germany
- Prior art keywords
- substituted
- chinolines
- use process
- compounds
- disorders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73569205P | 2005-11-10 | 2005-11-10 | |
PCT/US2006/044149 WO2007059108A2 (en) | 2005-11-10 | 2006-11-13 | Substituted quinolones and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602006018057D1 true DE602006018057D1 (de) | 2010-12-16 |
Family
ID=38049231
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602006018057T Active DE602006018057D1 (de) | 2005-11-10 | 2006-11-13 | Substituierte chinolone und verwendungsverfahren |
Country Status (11)
Country | Link |
---|---|
US (1) | US7557213B2 (de) |
EP (2) | EP1954274B8 (de) |
JP (1) | JP5175207B2 (de) |
AT (1) | ATE486875T1 (de) |
AU (1) | AU2006315514B2 (de) |
CA (1) | CA2629461C (de) |
DE (1) | DE602006018057D1 (de) |
DK (1) | DK1954274T3 (de) |
ES (1) | ES2353549T3 (de) |
HK (1) | HK1121075A1 (de) |
WO (1) | WO2007059108A2 (de) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2629461C (en) | 2005-11-10 | 2016-01-12 | Anita Melikian | Substituted quinolones and methods of use |
JP5564249B2 (ja) * | 2006-06-23 | 2014-07-30 | アレシア・バイオセラピューティクス・インコーポレーテッド | 癌に関与するポリヌクレオチド配列およびポリペプチド配列 |
US9512236B2 (en) | 2006-12-19 | 2016-12-06 | Ablynx N.V. | Amino acid sequences directed against GPCRS and polypeptides comprising the same for the treatment of GPCR-related diseases and disorders |
GB0716532D0 (en) | 2007-08-24 | 2007-10-03 | Angeletti P Ist Richerche Bio | Therapeutic compounds |
WO2009036341A2 (en) * | 2007-09-14 | 2009-03-19 | The Regents Of The University Of Michigan | Compositions and methods relating to hiv protease inhibition |
AU2009241392A1 (en) * | 2008-05-01 | 2009-11-05 | Merck Sharp & Dohme Corp. | 4-oxo-1,4-dihydroquinoline M1 receptor positive allosteric modulators |
RU2010151725A (ru) | 2008-05-16 | 2012-06-27 | Аблинкс Нв (Be) | Аминокислотные последовательности, направленные против cхcr4 и других gpcr, и соединения, включаюшие их |
EP2362908A4 (de) | 2008-11-03 | 2013-09-18 | Alethia Biotherapeutics Inc | Antikörper für die spezifische blockierung der biologischen aktivität eines tumorantigens |
DK2349273T3 (en) * | 2008-11-04 | 2015-07-13 | Chemocentryx Inc | Modulators of CXCR7 |
US20110014121A1 (en) * | 2008-11-04 | 2011-01-20 | Chemocentryx, Inc. | Modulators of cxcr7 |
US8853202B2 (en) * | 2008-11-04 | 2014-10-07 | Chemocentryx, Inc. | Modulators of CXCR7 |
PE20120493A1 (es) | 2009-06-29 | 2012-05-20 | Incyte Corp | Pirimidinonas como inhibidores de pi3k |
US8759359B2 (en) * | 2009-12-18 | 2014-06-24 | Incyte Corporation | Substituted heteroaryl fused derivatives as PI3K inhibitors |
US8680108B2 (en) * | 2009-12-18 | 2014-03-25 | Incyte Corporation | Substituted fused aryl and heteroaryl derivatives as PI3K inhibitors |
WO2011117423A1 (en) | 2010-03-26 | 2011-09-29 | Ablynx N.V. | Immunoglobulin single variable domains directed against cxcr7 |
CA2796311A1 (en) | 2010-04-14 | 2011-10-20 | Incyte Corporation | Fused derivatives as pi3k.delta. inhibitors |
US9062055B2 (en) | 2010-06-21 | 2015-06-23 | Incyte Corporation | Fused pyrrole derivatives as PI3K inhibitors |
BR112013003631B1 (pt) | 2010-08-18 | 2021-10-13 | Samumed, Llc | Beta- e gama-dicetonas e gama-hidroxicetonas e composições farmacêuticas que as compreendem |
AR084366A1 (es) | 2010-12-20 | 2013-05-08 | Incyte Corp | N-(1-(fenil sustituido)etil)-9h-purin-6-aminas como inhibidores de pi3k |
WO2012088266A2 (en) | 2010-12-22 | 2012-06-28 | Incyte Corporation | Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3 |
EP2963039A1 (de) * | 2011-02-24 | 2016-01-06 | The Regents of The University of California | Kleine moleküle zur endothelzellaktivierung |
WO2012125629A1 (en) | 2011-03-14 | 2012-09-20 | Incyte Corporation | Substituted diamino-pyrimidine and diamino-pyridine derivatives as pi3k inhibitors |
GB201104600D0 (en) | 2011-03-18 | 2011-05-04 | Pronoxis Ab | New compounds and medical uses |
US9126948B2 (en) | 2011-03-25 | 2015-09-08 | Incyte Holdings Corporation | Pyrimidine-4,6-diamine derivatives as PI3K inhibitors |
AU2012234284B2 (en) | 2011-03-28 | 2015-10-08 | Ablynx Nv | Bispecific anti-CXCR7 immunoglobulin single variable domains |
CA2888908A1 (en) | 2011-03-31 | 2012-10-04 | Alethia Biotherapeutics Inc. | Antibodies against kidney associated antigen 1 and antigen binding fragments thereof |
KR101982475B1 (ko) | 2011-09-02 | 2019-05-27 | 인사이트 홀딩스 코포레이션 | Pi3k 억제제로서 헤테로시클릴아민 |
JP6282597B2 (ja) | 2012-01-09 | 2018-02-21 | アー・デー・ツェー・セラピューティクス・エス・アー | 乳癌を治療する方法 |
US9403802B2 (en) | 2012-03-02 | 2016-08-02 | Takeda Pharmaceutical Company Limited | Heterocyclic compound and use therefor |
AR090548A1 (es) | 2012-04-02 | 2014-11-19 | Incyte Corp | Azaheterociclobencilaminas biciclicas como inhibidores de pi3k |
CA2876689C (en) | 2012-06-13 | 2022-04-26 | Incyte Corporation | Substituted tricyclic compounds as fgfr inhibitors |
US9388185B2 (en) | 2012-08-10 | 2016-07-12 | Incyte Holdings Corporation | Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors |
JP6211530B2 (ja) | 2012-11-19 | 2017-10-11 | 武田薬品工業株式会社 | 含窒素複素環化合物 |
ES2681593T3 (es) | 2012-11-29 | 2018-09-14 | Chemocentryx, Inc. | Antagonistas de CXCR7 |
US9266892B2 (en) | 2012-12-19 | 2016-02-23 | Incyte Holdings Corporation | Fused pyrazoles as FGFR inhibitors |
KR102252567B1 (ko) | 2013-02-22 | 2021-05-17 | 사뮤메드, 엘엘씨 | Wnt/베타-카테닌 신호전달 경로 활성자로서 감마-디케톤 |
HUE036571T2 (hu) | 2013-04-19 | 2018-07-30 | Incyte Holdings Corp | Biciklusos heterociklusok mint FGFR inhibitorok |
US9920010B2 (en) * | 2013-05-30 | 2018-03-20 | Idorsia Pharmaceuticals Ltd | CXCR7 receptor modulators |
GB201409044D0 (en) | 2014-05-21 | 2014-07-02 | Ucl Business Plc | New compounds |
WO2015191677A1 (en) | 2014-06-11 | 2015-12-17 | Incyte Corporation | Bicyclic heteroarylaminoalkyl phenyl derivatives as pi3k inhibitors |
CN105272964B (zh) * | 2014-07-08 | 2017-11-24 | 河南省医药科学研究院 | 6‑取代‑1‑((1‑取代苯基‑1,2,3‑三唑‑4‑基)甲基)‑4‑羰基喹啉‑3‑甲酸乙酯类化合物及其制备和应用 |
WO2016029021A1 (en) | 2014-08-20 | 2016-02-25 | Samumed, Llc | Gamma-diketones for treatment and prevention of aging skin and wrinkles |
US10851105B2 (en) | 2014-10-22 | 2020-12-01 | Incyte Corporation | Bicyclic heterocycles as FGFR4 inhibitors |
US10202368B2 (en) | 2014-12-01 | 2019-02-12 | Idorsia Pharmaceuticals Ltd. | CXCR7 receptor modulators |
MA41551A (fr) | 2015-02-20 | 2017-12-26 | Incyte Corp | Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4 |
US9580423B2 (en) | 2015-02-20 | 2017-02-28 | Incyte Corporation | Bicyclic heterocycles as FGFR4 inhibitors |
EP3259269B9 (de) | 2015-02-20 | 2020-03-04 | Incyte Corporation | Bizyklische heterozyklen als fgfr inhibitoren |
MY187502A (en) | 2015-02-27 | 2021-09-24 | Incyte Corp | Salts of pi3k inhibitor and processes for their preparation |
US9732097B2 (en) | 2015-05-11 | 2017-08-15 | Incyte Corporation | Process for the synthesis of a phosphoinositide 3-kinase inhibitor |
US9988401B2 (en) | 2015-05-11 | 2018-06-05 | Incyte Corporation | Crystalline forms of a PI3K inhibitor |
RU2720205C2 (ru) * | 2015-07-17 | 2020-04-27 | Фуджифилм Корпорэйшн | Азотсодержащее гетероциклическое соединение |
AR111960A1 (es) | 2017-05-26 | 2019-09-04 | Incyte Corp | Formas cristalinas de un inhibidor de fgfr y procesos para su preparación |
US11174257B2 (en) | 2018-05-04 | 2021-11-16 | Incyte Corporation | Salts of an FGFR inhibitor |
CR20200590A (es) | 2018-05-04 | 2021-04-26 | Incyte Corp | Formas sólidas de un inhibidor de fgfr y procesos para prepararlas |
CN113194956A (zh) | 2018-12-12 | 2021-07-30 | 凯莫森特里克斯股份有限公司 | 用于癌症治疗的cxcr7抑制剂 |
US11628162B2 (en) | 2019-03-08 | 2023-04-18 | Incyte Corporation | Methods of treating cancer with an FGFR inhibitor |
WO2021007269A1 (en) | 2019-07-09 | 2021-01-14 | Incyte Corporation | Bicyclic heterocycles as fgfr inhibitors |
CN114206338A (zh) | 2019-07-10 | 2022-03-18 | 凯莫森特里克斯股份有限公司 | 作为pd-l1抑制剂的二氢化茚类 |
KR20220100879A (ko) | 2019-10-14 | 2022-07-18 | 인사이트 코포레이션 | Fgfr 저해제로서의 이환식 헤테로사이클 |
WO2021076728A1 (en) | 2019-10-16 | 2021-04-22 | Incyte Corporation | Bicyclic heterocycles as fgfr inhibitors |
WO2021102370A1 (en) * | 2019-11-21 | 2021-05-27 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | METHODS AND MATERIALS FOR INHIBITING NF-kB ACTIVITY |
WO2021113479A1 (en) | 2019-12-04 | 2021-06-10 | Incyte Corporation | Tricyclic heterocycles as fgfr inhibitors |
CA3162010A1 (en) | 2019-12-04 | 2021-06-10 | Incyte Corporation | Derivatives of an fgfr inhibitor |
WO2021146424A1 (en) | 2020-01-15 | 2021-07-22 | Incyte Corporation | Bicyclic heterocycles as fgfr inhibitors |
AR126102A1 (es) | 2021-06-09 | 2023-09-13 | Incyte Corp | Heterociclos tricíclicos como inhibidores de fgfr |
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GB0218630D0 (en) | 2002-08-10 | 2002-09-18 | Tanabe Seiyaku Co | Novel compounds |
CN1747929B (zh) * | 2002-12-20 | 2010-04-28 | 坎莫森特里克斯公司 | 趋化因子i-tac或sdf-1结合于ccxckr2受体的抑制剂 |
MXPA05009688A (es) * | 2003-03-12 | 2005-12-05 | Abbott Lab | Derivados de naftiridina como agentes antibacterianos. |
CA2629461C (en) | 2005-11-10 | 2016-01-12 | Anita Melikian | Substituted quinolones and methods of use |
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2006
- 2006-11-13 CA CA2629461A patent/CA2629461C/en active Active
- 2006-11-13 AT AT06844355T patent/ATE486875T1/de active
- 2006-11-13 AU AU2006315514A patent/AU2006315514B2/en active Active
- 2006-11-13 EP EP06844355A patent/EP1954274B8/de active Active
- 2006-11-13 JP JP2008540276A patent/JP5175207B2/ja active Active
- 2006-11-13 DE DE602006018057T patent/DE602006018057D1/de active Active
- 2006-11-13 EP EP10013268A patent/EP2314590A1/de not_active Withdrawn
- 2006-11-13 ES ES06844355T patent/ES2353549T3/es active Active
- 2006-11-13 DK DK06844355.5T patent/DK1954274T3/da active
- 2006-11-13 US US11/599,183 patent/US7557213B2/en active Active
- 2006-11-13 WO PCT/US2006/044149 patent/WO2007059108A2/en active Application Filing
-
2009
- 2009-02-10 HK HK09101211.2A patent/HK1121075A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1954274A4 (de) | 2009-01-07 |
HK1121075A1 (en) | 2009-04-17 |
EP1954274B1 (de) | 2010-11-03 |
EP2314590A1 (de) | 2011-04-27 |
ATE486875T1 (de) | 2010-11-15 |
US7557213B2 (en) | 2009-07-07 |
AU2006315514B2 (en) | 2012-03-01 |
WO2007059108A3 (en) | 2007-12-13 |
DK1954274T3 (da) | 2011-01-31 |
EP1954274A2 (de) | 2008-08-13 |
ES2353549T3 (es) | 2011-03-03 |
CA2629461A1 (en) | 2007-05-24 |
JP2009515902A (ja) | 2009-04-16 |
EP1954274B8 (de) | 2011-01-12 |
US20070167443A1 (en) | 2007-07-19 |
AU2006315514A1 (en) | 2007-05-24 |
WO2007059108A2 (en) | 2007-05-24 |
CA2629461C (en) | 2016-01-12 |
JP5175207B2 (ja) | 2013-04-03 |
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