DE602005008731D1 - Durch röntgen- und/oder uv-strahlen aktivierbare partikel, deren herstellung und deren therapeutische oder diagnostische verwendung - Google Patents

Durch röntgen- und/oder uv-strahlen aktivierbare partikel, deren herstellung und deren therapeutische oder diagnostische verwendung

Info

Publication number
DE602005008731D1
DE602005008731D1 DE602005008731T DE602005008731T DE602005008731D1 DE 602005008731 D1 DE602005008731 D1 DE 602005008731D1 DE 602005008731 T DE602005008731 T DE 602005008731T DE 602005008731 T DE602005008731 T DE 602005008731T DE 602005008731 D1 DE602005008731 D1 DE 602005008731D1
Authority
DE
Germany
Prior art keywords
particles
therapeutic
ray
manufacture
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005008731T
Other languages
English (en)
Inventor
Laurent Levy
Jean-Francois Hochepied
Jeremy Balencie
Paras Nath Prasad
Earl Jim Bergey
Edouard Andre Panak
Abdel Kader Boussaha
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanobiotix SA
Original Assignee
Nanobiotix SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanobiotix SA filed Critical Nanobiotix SA
Publication of DE602005008731D1 publication Critical patent/DE602005008731D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0052—Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0409—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is not a halogenated organic compound
    • A61K49/0414—Particles, beads, capsules or spheres
    • A61K49/0423—Nanoparticles, nanobeads, nanospheres, nanocapsules, i.e. having a size or diameter smaller than 1 micrometer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0661—Radiation therapy using light characterised by the wavelength of light used ultraviolet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092—Details
    • A61N2005/1098—Enhancing the effect of the particle by an injected agent or implanted device

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nanotechnology (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Paints Or Removers (AREA)
DE602005008731T 2004-05-10 2005-05-09 Durch röntgen- und/oder uv-strahlen aktivierbare partikel, deren herstellung und deren therapeutische oder diagnostische verwendung Active DE602005008731D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0405036A FR2869803B1 (fr) 2004-05-10 2004-05-10 Particules activables, preparation et utilisations
PCT/FR2005/001145 WO2005120590A1 (fr) 2004-05-10 2005-05-09 Particules activables, preparation et utilisations

Publications (1)

Publication Number Publication Date
DE602005008731D1 true DE602005008731D1 (de) 2008-09-18

Family

ID=34945762

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005008731T Active DE602005008731D1 (de) 2004-05-10 2005-05-09 Durch röntgen- und/oder uv-strahlen aktivierbare partikel, deren herstellung und deren therapeutische oder diagnostische verwendung

Country Status (25)

Country Link
US (2) US9162079B2 (de)
EP (1) EP1744789B1 (de)
JP (1) JP5150251B2 (de)
KR (2) KR101234334B1 (de)
CN (1) CN100592921C (de)
AT (1) ATE403444T1 (de)
AU (1) AU2005251499B2 (de)
BR (1) BRPI0510290B8 (de)
CA (1) CA2564197C (de)
CY (1) CY1108369T1 (de)
DE (1) DE602005008731D1 (de)
DK (1) DK1744789T3 (de)
EA (1) EA010246B1 (de)
ES (1) ES2312004T3 (de)
FR (1) FR2869803B1 (de)
HK (1) HK1099508A1 (de)
HR (1) HRP20080534T3 (de)
IL (1) IL178877A (de)
MX (1) MXPA06013095A (de)
PL (1) PL1744789T3 (de)
PT (1) PT1744789E (de)
RS (1) RS50615B (de)
SI (1) SI1744789T1 (de)
WO (1) WO2005120590A1 (de)
ZA (1) ZA200610255B (de)

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FR2867180B1 (fr) 2004-03-02 2006-06-16 Univ Claude Bernard Lyon Nanoparticules hybrides comprenant un coeur de ln203 porteuses de ligands biologiques et leur procede de preparation
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US20070218049A1 (en) * 2006-02-02 2007-09-20 Wei Chen Nanoparticle based photodynamic therapy and methods of making and using same
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EP1852107A1 (de) * 2006-04-19 2007-11-07 Nanobiotix Zusammensetzungen enthaltend magnetische Nanopartikel sowie deren Verwendung
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US9488916B2 (en) 2007-04-08 2016-11-08 Immunolight, Llc. Interior energy-activation of photo-reactive species inside a medium or body
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FR2922106B1 (fr) * 2007-10-16 2011-07-01 Univ Claude Bernard Lyon Utilisation de nanoparticules a base de lanthanides comme agents radiosensibilisants.
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EP2328620A2 (de) 2008-07-31 2011-06-08 Alma Mater Studiorum - Università di Bologna Aktive teilchen für bioanalytische anwendungen und verfahren zu ihrer herstellung
JP5908396B2 (ja) 2009-04-21 2016-04-26 イミュノライト・エルエルシー ｉｎｓｉｔｕフォトバイオモジュレーションのための、非侵襲的エネルギーアップコンバージョン方法およびシステム
CN107149689A (zh) 2009-11-10 2017-09-12 免疫之光有限责任公司 对可辐射固化介质进行固化的系统和产生光的方法
GB0921596D0 (en) 2009-12-09 2010-01-27 Isis Innovation Particles for the treatment of cancer in combination with radiotherapy
SI2567257T1 (sl) 2010-05-06 2021-09-30 Immunolight, Llc. Lepilni vezivni sestavek in postopek uporabe
US9572880B2 (en) 2010-08-27 2017-02-21 Sienna Biopharmaceuticals, Inc. Ultrasound delivery of nanoparticles
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AU2012351537B2 (en) 2011-12-16 2017-03-02 Nanobiotix Nanoparticles comprising metallic and hafnium oxide materials, preparation and uses thereof
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JP6484229B2 (ja) * 2013-06-20 2019-03-13 ナノビオティックスＮａｎｏｂｉｏｔｉｘ 腫瘍学に使用するための組成物および方法
FR3018451A1 (fr) * 2014-03-13 2015-09-18 Chromalys Nanoparticules pour leur utilisation dans la detection de tumeurs mobiles
US10780164B2 (en) * 2014-04-03 2020-09-22 The Governing Council Of The University Of Toronto Multifunctional nanoparticle compositions and uses thereof
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US10806694B2 (en) 2014-10-14 2020-10-20 The University Of Chicago Nanoparticles for photodynamic therapy, X-ray induced photodynamic therapy, radiotherapy, radiodynamic therapy, chemotherapy, immunotherapy, and any combination thereof
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WO2017201528A1 (en) 2016-05-20 2017-11-23 The University Of Chicago Nanoparticles for chemotherapy, targeted therapy, photodynamic therapy, immunotherapy, and any combination thereof
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US11191836B2 (en) 2018-06-01 2021-12-07 Tae Life Sciences, Llc Biodegradable nanocarrier(s) (BPMOs) for neutron capture therapy and methods thereof
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US20070218049A1 (en) * 2006-02-02 2007-09-20 Wei Chen Nanoparticle based photodynamic therapy and methods of making and using same

Also Published As

Publication number Publication date
JP2007536356A (ja) 2007-12-13
BRPI0510290B1 (pt) 2021-06-01
ES2312004T3 (es) 2009-02-16
ZA200610255B (en) 2008-09-25
US9433800B2 (en) 2016-09-06
BRPI0510290A (pt) 2007-10-30
KR20070014172A (ko) 2007-01-31
PT1744789E (pt) 2008-11-04
US9162079B2 (en) 2015-10-20
AU2005251499B2 (en) 2010-06-10
CA2564197A1 (fr) 2005-12-22
US20150238775A1 (en) 2015-08-27
IL178877A (en) 2010-12-30
EP1744789B1 (de) 2008-08-06
FR2869803A1 (fr) 2005-11-11
CA2564197C (fr) 2013-05-07
WO2005120590A1 (fr) 2005-12-22
AU2005251499A1 (en) 2005-12-22
DK1744789T3 (da) 2008-12-08
SI1744789T1 (sl) 2008-10-31
HRP20080534T3 (en) 2008-11-30
KR20120123731A (ko) 2012-11-09
PL1744789T3 (pl) 2009-01-30
EA010246B1 (ru) 2008-06-30
CN1950111A (zh) 2007-04-18
IL178877A0 (en) 2007-03-08
ATE403444T1 (de) 2008-08-15
US20070217996A1 (en) 2007-09-20
CY1108369T1 (el) 2014-02-12
BRPI0510290B8 (pt) 2021-10-19
CN100592921C (zh) 2010-03-03
JP5150251B2 (ja) 2013-02-20
MXPA06013095A (es) 2007-04-27
BRPI0510290A8 (pt) 2019-01-02
RS50615B (sr) 2010-06-30
HK1099508A1 (en) 2007-08-17
FR2869803B1 (fr) 2006-07-28
KR101234334B1 (ko) 2013-02-18
EA200602077A1 (ru) 2007-04-27
EP1744789A1 (de) 2007-01-24

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