ATE411981T1 - Tetrahydrocarbazolderivate und deren pharmazeutische verwendung - Google Patents
Tetrahydrocarbazolderivate und deren pharmazeutische verwendungInfo
- Publication number
- ATE411981T1 ATE411981T1 AT04776279T AT04776279T ATE411981T1 AT E411981 T1 ATE411981 T1 AT E411981T1 AT 04776279 T AT04776279 T AT 04776279T AT 04776279 T AT04776279 T AT 04776279T AT E411981 T1 ATE411981 T1 AT E411981T1
- Authority
- AT
- Austria
- Prior art keywords
- pharmaceutical use
- tetrahydrocarbazole derivatives
- tetrahydrocarbazole
- derivatives
- compounds
- Prior art date
Links
- XKLNOVWDVMWTOB-UHFFFAOYSA-N 2,3,4,9-tetrahydro-1h-carbazole Chemical class N1C2=CC=CC=C2C2=C1CCCC2 XKLNOVWDVMWTOB-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 241000701806 Human papillomavirus Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47725103P | 2003-06-10 | 2003-06-10 | |
| US49782303P | 2003-08-26 | 2003-08-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE411981T1 true ATE411981T1 (de) | 2008-11-15 |
Family
ID=33555453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04776279T ATE411981T1 (de) | 2003-06-10 | 2004-06-07 | Tetrahydrocarbazolderivate und deren pharmazeutische verwendung |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7351733B2 (de) |
| EP (1) | EP1654228B1 (de) |
| JP (1) | JP2007501284A (de) |
| KR (1) | KR20060017545A (de) |
| AT (1) | ATE411981T1 (de) |
| AU (1) | AU2004247676A1 (de) |
| BR (1) | BRPI0411085A (de) |
| CA (1) | CA2528321A1 (de) |
| CO (1) | CO5660287A2 (de) |
| DE (1) | DE602004017326D1 (de) |
| ES (1) | ES2314446T3 (de) |
| IL (1) | IL171974A0 (de) |
| MA (1) | MA27880A1 (de) |
| NO (1) | NO20055741L (de) |
| RU (1) | RU2318810C2 (de) |
| WO (1) | WO2004110999A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602004019541D1 (de) | 2003-08-26 | 2009-04-02 | Smithkline Beecham Corp | Cycloalkyläbü kondensierte indole |
| US8076352B2 (en) | 2004-03-15 | 2011-12-13 | Ptc Therapeutics, Inc. | Administration of carboline derivatives useful in the treatment of cancer and other diseases |
| PT1737461E (pt) | 2004-03-15 | 2013-03-18 | Ptc Therapeutics Inc | Derivados de carbolina úteis na inibição de angiogénese |
| US8076353B2 (en) | 2004-03-15 | 2011-12-13 | Ptc Therapeutics, Inc. | Inhibition of VEGF translation |
| US7767689B2 (en) | 2004-03-15 | 2010-08-03 | Ptc Therapeutics, Inc. | Carboline derivatives useful in the treatment of cancer |
| WO2006012310A2 (en) * | 2004-06-25 | 2006-02-02 | Genzyme Corporation | Carbazole derivatives for treating polycystic kidney disease |
| US20090156621A1 (en) * | 2004-11-22 | 2009-06-18 | Kristian Gudmundsson | Hcv inhibitors |
| CA2588384A1 (en) * | 2004-11-23 | 2006-06-22 | Ptc Therapeutics, Inc. | Tetrahydrocarbazoles as active agents for inhibiting vegf production by translational control |
| WO2007002051A1 (en) * | 2005-06-22 | 2007-01-04 | Smithkline Beecham Corporation | Carboline derivatives and their use as inhibitors of flaviviridae infections |
| WO2013139929A1 (en) * | 2012-03-22 | 2013-09-26 | Ludwig-Maximilians-Universität München | Novel means and methods for treating diseases of the central nervous system, metabolic and cardiac diseases and aging |
| JP6653573B2 (ja) | 2012-05-22 | 2020-02-26 | トラスティーズ・オブ・ダートマウス・カレッジ | シクロアルカニル［ｂ］インドール、シクロアルカニル［ｂ］ベンゾフラン、シクロアルカニル［ｂ］ベンゾチオフェンを合成するための方法、化合物および使用の方法 |
| EP2690091A1 (de) | 2012-07-25 | 2014-01-29 | Studiengesellschaft Kohle mbH | Verfahren zur Herstellung von substituierten Indolderivaten |
| KR101671484B1 (ko) | 2016-07-21 | 2016-11-01 | 김정환 | 오셀타미비르(Oseltamivir)를 포함하는 인유두종 바이러스 치료용 약학적 조성물 |
| US10882821B1 (en) | 2017-09-26 | 2021-01-05 | The Board Of Trustees Of The Leland Stanford Junior University | Enantiomeric compound for the reduction of the deleterious activity of extended nucleotide repeat containing genes |
| WO2021183980A1 (en) * | 2020-03-13 | 2021-09-16 | Fmc Corporation | Substituted pyrimidines and triazines as herbicides |
| CN113995758B (zh) * | 2021-11-04 | 2023-06-02 | 中山大学 | 咔唑-嘧啶衍生物在制备治疗抗肿瘤药物中的应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE507797C (de) * | 1927-05-14 | 1930-09-20 | I G Farbenindustrie Akt Ges | Verfahren zur Herstellung von 1-Aminocarbazol und seinen Derivaten |
| GB8924392D0 (en) * | 1989-10-30 | 1989-12-20 | Bayer Ag | Substituted cycloalkano/b/dihydroindole-and-indolesulphonamides |
| GB9008108D0 (en) * | 1990-04-10 | 1990-06-06 | Bayer Ag | Cycloalkano(b)dihydroindoles and-indolesulphonamides substituted by heterocycles |
| US5100891A (en) | 1991-01-18 | 1992-03-31 | Hoechst-Roussel Pharmaceuticals Inc. | Substituted 1,2,3,4-tetrahydrocyclopent[b]indoles, 1,2,3,3a,4,8a-hexahydrocyclopent[B]indoles and related compounds |
| CA2106642C (en) * | 1992-10-14 | 2005-08-16 | Peter Bod | Carbazolone derivatives and process for preparing the same |
| JP2950433B2 (ja) * | 1995-07-10 | 1999-09-20 | インターナシヨナル・ビジネス・マシーンズ・コーポレーシヨン | バッテリ収納装置 |
| GB0015904D0 (en) * | 2000-06-28 | 2000-08-23 | Hoffmann La Roche | Inhibitors of HPV E1 helicase enzyme |
| RU2319692C2 (ru) * | 2001-12-14 | 2008-03-20 | Центарис Гмбх | Производные тетрагидрокарбазола, способ получения производных тетрагидрокарбазола (варианты), их применение (варианты) и фармацевтическая композиция, обладающая активностью антагониста гонадотропин-рилизинг-гормона (варианты) |
| DE10164564B4 (de) * | 2001-12-14 | 2007-05-16 | Zentaris Gmbh | Tetrahydrocarbazolderivate als Liganden für G-Protein gekoppelte Rezeptoren (GPCR) |
-
2004
- 2004-06-07 RU RU2005138124/04A patent/RU2318810C2/ru not_active IP Right Cessation
- 2004-06-07 WO PCT/US2004/017660 patent/WO2004110999A1/en not_active Ceased
- 2004-06-07 AT AT04776279T patent/ATE411981T1/de not_active IP Right Cessation
- 2004-06-07 US US10/560,013 patent/US7351733B2/en not_active Expired - Fee Related
- 2004-06-07 JP JP2006533561A patent/JP2007501284A/ja active Pending
- 2004-06-07 ES ES04776279T patent/ES2314446T3/es not_active Expired - Lifetime
- 2004-06-07 CA CA002528321A patent/CA2528321A1/en not_active Abandoned
- 2004-06-07 EP EP04776279A patent/EP1654228B1/de not_active Expired - Lifetime
- 2004-06-07 KR KR1020057023781A patent/KR20060017545A/ko not_active Withdrawn
- 2004-06-07 BR BRPI0411085-4A patent/BRPI0411085A/pt not_active IP Right Cessation
- 2004-06-07 DE DE602004017326T patent/DE602004017326D1/de not_active Expired - Lifetime
- 2004-06-07 AU AU2004247676A patent/AU2004247676A1/en not_active Abandoned
-
2005
- 2005-11-15 IL IL171974A patent/IL171974A0/en unknown
- 2005-12-05 NO NO20055741A patent/NO20055741L/no not_active Application Discontinuation
- 2005-12-09 MA MA28646A patent/MA27880A1/fr unknown
- 2005-12-15 CO CO05126713A patent/CO5660287A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE602004017326D1 (de) | 2008-12-04 |
| CO5660287A2 (es) | 2006-07-31 |
| IL171974A0 (en) | 2006-04-10 |
| ES2314446T3 (es) | 2009-03-16 |
| CA2528321A1 (en) | 2004-12-23 |
| NO20055741D0 (no) | 2005-12-05 |
| NO20055741L (no) | 2006-01-06 |
| EP1654228A1 (de) | 2006-05-10 |
| JP2007501284A (ja) | 2007-01-25 |
| EP1654228B1 (de) | 2008-10-22 |
| US20060161002A1 (en) | 2006-07-20 |
| MA27880A1 (fr) | 2006-05-02 |
| US7351733B2 (en) | 2008-04-01 |
| AU2004247676A1 (en) | 2004-12-23 |
| RU2005138124A (ru) | 2006-07-10 |
| BRPI0411085A (pt) | 2006-07-25 |
| KR20060017545A (ko) | 2006-02-23 |
| WO2004110999A1 (en) | 2004-12-23 |
| RU2318810C2 (ru) | 2008-03-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |