ZA200603863B - Combination for HCV treatment - Google Patents
Combination for HCV treatment Download PDFInfo
- Publication number
- ZA200603863B ZA200603863B ZA200603863A ZA200603863A ZA200603863B ZA 200603863 B ZA200603863 B ZA 200603863B ZA 200603863 A ZA200603863 A ZA 200603863A ZA 200603863 A ZA200603863 A ZA 200603863A ZA 200603863 B ZA200603863 B ZA 200603863B
- Authority
- ZA
- South Africa
- Prior art keywords
- inhibitor
- hepatitis
- virus
- cytochrome
- protease
- Prior art date
Links
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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Landscapes
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| AR045596A1 (es) | 2003-09-05 | 2005-11-02 | Vertex Pharma | Inhibidores de proteasas de serina en particular proteasa ns3-ns4a del vhc |
| NZ588471A (en) * | 2004-06-08 | 2012-02-24 | Vertex Pharma | Forms and Formulations of VX-950 |
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| US20070105781A1 (en) * | 2005-08-02 | 2007-05-10 | Steve Lyons | Inhibitors of serine proteases |
| US8399615B2 (en) | 2005-08-19 | 2013-03-19 | Vertex Pharmaceuticals Incorporated | Processes and intermediates |
| AR055395A1 (es) * | 2005-08-26 | 2007-08-22 | Vertex Pharma | Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c |
| US7964624B1 (en) * | 2005-08-26 | 2011-06-21 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases |
| EP2340836A1 (en) | 2006-02-27 | 2011-07-06 | Vertex Pharmceuticals Incorporated | Co-crystals comprising VX-950 and their pharmaceutical compositions |
| WO2007103934A2 (en) * | 2006-03-06 | 2007-09-13 | Abbott Laboratories | Compositions and methods of use of ritonavir for treating hcv |
| CA2646229A1 (en) | 2006-03-16 | 2007-09-27 | Vertex Pharmaceuticals Incorporated | Deuterated hepatitis c protease inhibitors |
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| EP2007789B1 (en) | 2006-04-11 | 2015-05-20 | Novartis AG | Spirocyclic HCV/HIV inhibitors and their uses |
| WO2007149382A2 (en) * | 2006-06-19 | 2007-12-27 | The Cleveland Clinic Foundation | Therapeutic compositions and methods useful in treating hepatitis |
| CA2653374A1 (en) * | 2006-07-07 | 2008-01-24 | Manoj C. Desai | Modulators of pharmacokinetic properties of therapeutics |
| EP2112925A4 (en) * | 2006-11-15 | 2013-01-09 | Abbott Lab | SOLID PHARMACEUTICAL DOSAGE FORMULATIONS |
| EP2134717A2 (en) * | 2007-02-27 | 2009-12-23 | Vertex Pharmceuticals Incorporated | Inhibitors of serine proteases |
| AR065498A1 (es) * | 2007-02-27 | 2009-06-10 | Vertex Pharma | Co- critales de vx-950 (un inhibidor del virus de la hepatitis c) y composiciones farmaceuticas que los comprenden |
| EP2170851B1 (en) * | 2007-07-06 | 2013-09-04 | Gilead Sciences, Inc. | Modulators of pharmacokinetic properties of therapeutics |
| CA2704284A1 (en) * | 2007-08-30 | 2009-03-12 | Vertex Pharmaceuticals Incorporated | Co-crystals and pharmaceutical compositions comprising the same |
| US20090082366A1 (en) * | 2007-09-26 | 2009-03-26 | Protia, Llc | Deuterium-enriched telaprevir |
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| TWI583405B (zh) * | 2008-02-28 | 2017-05-21 | 艾伯維有限公司 | 錠劑及其製備 |
| JP2012513409A (ja) * | 2008-12-23 | 2012-06-14 | アボット・ラボラトリーズ | 抗ウイルス化合物 |
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| EA029081B9 (ru) | 2013-01-31 | 2018-09-28 | Джилид Фармассет Ллс | Комбинированный состав двух противовирусных соединений |
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| TWI771272B (zh) * | 2015-06-30 | 2022-07-21 | 美商伊格集團國際股份有限公司 | 克立咪唑（ｃｌｅｍｉｚｏｌｅ）化合物於預防及治療肝癌之用途 |
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|---|---|---|---|---|
| FR2779653B1 (fr) * | 1998-06-11 | 2002-12-20 | Inst Nat Sante Rech Med | Utilisation de composes modulateurs du proteasome en therapie |
| SV2003000617A (es) * | 2000-08-31 | 2003-01-13 | Lilly Co Eli | Inhibidores de la proteasa peptidomimetica ref. x-14912m |
| PL395097A1 (pl) * | 2001-06-11 | 2011-10-10 | Vertex Pharmaceuticals (Canada) Incorporated | Sposób wytwarzania związku o wzorze A stanowiącego pochodną tiofenu |
| EP1613620A1 (en) * | 2003-04-11 | 2006-01-11 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases, particularly hcv ns3-ns4a protease |
| JP4745230B2 (ja) * | 2003-07-18 | 2011-08-10 | バーテックス ファーマシューティカルズ インコーポレイテッド | セリンプロテアーゼ、特に、ｈｃｖｎｓ３−ｎｓ４ａプロテアーゼの阻害剤 |
| AR045596A1 (es) * | 2003-09-05 | 2005-11-02 | Vertex Pharma | Inhibidores de proteasas de serina en particular proteasa ns3-ns4a del vhc |
| KR20060130027A (ko) * | 2003-10-10 | 2006-12-18 | 버텍스 파마슈티칼스 인코포레이티드 | 세린 프로테아제, 특히 ｈｃｖ ｎｓ3-ｎｓ4ａ 프로테아제의억제제 |
| AR055395A1 (es) * | 2005-08-26 | 2007-08-22 | Vertex Pharma | Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c |
-
2004
- 2004-10-27 PT PT04810032T patent/PT1677827E/pt unknown
- 2004-10-27 ES ES04810032T patent/ES2319775T3/es active Active
- 2004-10-27 CN CNA200480037505XA patent/CN1893978A/zh active Pending
- 2004-10-27 RU RU2006118359/15A patent/RU2006118359A/ru not_active Application Discontinuation
- 2004-10-27 DK DK04810032T patent/DK1677827T3/da active
- 2004-10-27 MX MXPA06004723A patent/MXPA06004723A/es active IP Right Grant
- 2004-10-27 AU AU2004285503A patent/AU2004285503A1/en not_active Abandoned
- 2004-10-27 DE DE602004018363T patent/DE602004018363D1/de active Active
- 2004-10-27 SI SI200431034T patent/SI1677827T1/sl unknown
- 2004-10-27 WO PCT/US2004/035549 patent/WO2005042020A2/en active Application Filing
- 2004-10-27 AT AT04810032T patent/ATE416789T1/de active
- 2004-10-27 BR BRPI0415935-7A patent/BRPI0415935A/pt not_active IP Right Cessation
- 2004-10-27 JP JP2006538195A patent/JP2007509950A/ja active Pending
- 2004-10-27 ZA ZA200603863A patent/ZA200603863B/en unknown
- 2004-10-27 CA CA002543696A patent/CA2543696A1/en not_active Abandoned
- 2004-10-27 EP EP04810032A patent/EP1677827B1/en active Active
- 2004-10-27 PL PL04810032T patent/PL1677827T3/pl unknown
- 2004-10-27 US US10/974,538 patent/US20060003942A1/en not_active Abandoned
- 2004-10-27 KR KR1020067010372A patent/KR20060120162A/ko not_active Application Discontinuation
-
2006
- 2006-04-26 IL IL175211A patent/IL175211A0/en unknown
- 2006-05-29 NO NO20062428A patent/NO20062428L/no not_active Application Discontinuation
-
2009
- 2009-03-10 CY CY20091100274T patent/CY1110176T1/el unknown
- 2009-06-23 US US12/490,196 patent/US20100015090A1/en not_active Abandoned
-
2012
- 2012-01-23 US US13/355,638 patent/US20120114604A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA06004723A (es) | 2006-07-05 |
| RU2006118359A (ru) | 2007-12-10 |
| AU2004285503A1 (en) | 2005-05-12 |
| US20120114604A1 (en) | 2012-05-10 |
| CA2543696A1 (en) | 2005-05-12 |
| SI1677827T1 (sl) | 2009-06-30 |
| CY1110176T1 (el) | 2015-01-14 |
| JP2007509950A (ja) | 2007-04-19 |
| BRPI0415935A (pt) | 2007-01-02 |
| PT1677827E (pt) | 2009-03-13 |
| US20100015090A1 (en) | 2010-01-21 |
| PL1677827T3 (pl) | 2009-06-30 |
| WO2005042020A2 (en) | 2005-05-12 |
| NO20062428L (no) | 2006-05-29 |
| WO2005042020A3 (en) | 2005-06-23 |
| KR20060120162A (ko) | 2006-11-24 |
| IL175211A0 (en) | 2006-09-05 |
| DK1677827T3 (da) | 2009-03-30 |
| EP1677827A2 (en) | 2006-07-12 |
| CN1893978A (zh) | 2007-01-10 |
| US20060003942A1 (en) | 2006-01-05 |
| ES2319775T3 (es) | 2009-05-12 |
| DE602004018363D1 (de) | 2009-01-22 |
| ATE416789T1 (de) | 2008-12-15 |
| EP1677827B1 (en) | 2008-12-10 |
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