ZA200509239B - Nasal pharmaceutical formulations and methods of using the same - Google Patents

Nasal pharmaceutical formulations and methods of using the same Download PDF

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Publication number
ZA200509239B
ZA200509239B ZA200509239A ZA200509239A ZA200509239B ZA 200509239 B ZA200509239 B ZA 200509239B ZA 200509239 A ZA200509239 A ZA 200509239A ZA 200509239 A ZA200509239 A ZA 200509239A ZA 200509239 B ZA200509239 B ZA 200509239B
Authority
ZA
South Africa
Prior art keywords
drug substance
particle size
microns
less
formulation
Prior art date
Application number
ZA200509239A
Other languages
English (en)
Inventor
Chaudry Imtiaz
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA200509239B publication Critical patent/ZA200509239B/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029Radiation
    • A61L2/0035Gamma radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200509239A 2003-04-16 2005-11-15 Nasal pharmaceutical formulations and methods of using the same ZA200509239B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/414,682 US9808471B2 (en) 2003-04-16 2003-04-16 Nasal pharmaceutical formulations and methods of using the same

Publications (1)

Publication Number Publication Date
ZA200509239B true ZA200509239B (en) 2007-04-25

Family

ID=33158745

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA200509240A ZA200509240B (en) 2003-04-16 2005-11-15 Formulations and methods for treating rhinosinusitis
ZA200509239A ZA200509239B (en) 2003-04-16 2005-11-15 Nasal pharmaceutical formulations and methods of using the same

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ZA200509240A ZA200509240B (en) 2003-04-16 2005-11-15 Formulations and methods for treating rhinosinusitis

Country Status (15)

Country Link
US (3) US9808471B2 (ja)
EP (1) EP1613280B1 (ja)
JP (1) JP4680180B2 (ja)
KR (1) KR101312311B1 (ja)
CN (3) CN1774238B (ja)
AU (2) AU2004229147A1 (ja)
BR (1) BRPI0409381A (ja)
CA (1) CA2522292C (ja)
ES (1) ES2643077T3 (ja)
HK (1) HK1164133A1 (ja)
MX (1) MXPA05011107A (ja)
PL (2) PL222060B1 (ja)
RU (1) RU2380090C2 (ja)
WO (1) WO2004091574A1 (ja)
ZA (2) ZA200509240B (ja)

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US9808471B2 (en) 2003-04-16 2017-11-07 Mylan Specialty Lp Nasal pharmaceutical formulations and methods of using the same
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US7811606B2 (en) * 2003-04-16 2010-10-12 Dey, L.P. Nasal pharmaceutical formulations and methods of using the same
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PL2522365T3 (pl) 2004-11-24 2017-05-31 Meda Pharmaceuticals Inc. Kompozycje zawierające azelastynę i sposoby ich zastosowania
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CN107320449B (zh) * 2017-08-07 2020-09-15 武汉武药科技有限公司 丙酸氟替卡松鼻喷雾剂及其制备方法
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Also Published As

Publication number Publication date
RU2005135335A (ru) 2006-05-10
AU2004229147A1 (en) 2004-10-28
CN1774238A (zh) 2006-05-17
RU2380090C2 (ru) 2010-01-27
CN102319209A (zh) 2012-01-18
PL208784B1 (pl) 2011-06-30
EP1613280B1 (en) 2017-07-12
US20040208830A1 (en) 2004-10-21
PL377854A1 (pl) 2006-02-20
ZA200509240B (en) 2007-04-25
KR20060003010A (ko) 2006-01-09
US9808471B2 (en) 2017-11-07
KR101312311B1 (ko) 2013-10-10
CN1805730A (zh) 2006-07-19
US20080050442A1 (en) 2008-02-28
AU2010203026B2 (en) 2012-07-05
CN102319209B (zh) 2013-09-04
AU2010203026A1 (en) 2010-08-05
MXPA05011107A (es) 2006-05-19
HK1164133A1 (en) 2012-09-21
CA2522292C (en) 2011-11-08
CN1774238B (zh) 2013-09-04
US20060051299A1 (en) 2006-03-09
WO2004091574A1 (en) 2004-10-28
JP4680180B2 (ja) 2011-05-11
JP2006523630A (ja) 2006-10-19
US7972626B2 (en) 2011-07-05
PL377931A1 (pl) 2006-02-20
PL222060B1 (pl) 2016-06-30
EP1613280A1 (en) 2006-01-11
ES2643077T3 (es) 2017-11-21
CA2522292A1 (en) 2004-10-28
BRPI0409381A (pt) 2006-04-18

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