ZA200408412B - Compressed tablets comprising microcapsules with modified release - Google Patents
Compressed tablets comprising microcapsules with modified release Download PDFInfo
- Publication number
- ZA200408412B ZA200408412B ZA200408412A ZA200408412A ZA200408412B ZA 200408412 B ZA200408412 B ZA 200408412B ZA 200408412 A ZA200408412 A ZA 200408412A ZA 200408412 A ZA200408412 A ZA 200408412A ZA 200408412 B ZA200408412 B ZA 200408412B
- Authority
- ZA
- South Africa
- Prior art keywords
- microcapsules
- tablet according
- tablet
- overcoating
- dry weight
- Prior art date
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- 239000003094 microcapsule Substances 0.000 title claims description 158
- 239000007891 compressed tablet Substances 0.000 title 1
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- 239000002245 particle Substances 0.000 claims description 55
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- 230000002035 prolonged effect Effects 0.000 claims description 32
- 239000007888 film coating Substances 0.000 claims description 29
- 238000009501 film coating Methods 0.000 claims description 29
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- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 21
- 235000019359 magnesium stearate Nutrition 0.000 claims description 19
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0203336A FR2837100B1 (fr) | 2002-03-18 | 2002-03-18 | Comprimes a bases de microcapsules a liberation modifiee |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200408412B true ZA200408412B (en) | 2006-08-30 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200408412A ZA200408412B (en) | 2002-03-18 | 2004-10-18 | Compressed tablets comprising microcapsules with modified release |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8507003B2 (de) |
| EP (1) | EP1485071A2 (de) |
| JP (1) | JP2005527522A (de) |
| KR (1) | KR20040105773A (de) |
| CN (1) | CN1642530A (de) |
| AU (1) | AU2003242818B2 (de) |
| BR (1) | BR0308487A (de) |
| CA (1) | CA2479057C (de) |
| FR (1) | FR2837100B1 (de) |
| IL (2) | IL163813A0 (de) |
| MX (1) | MXPA04009010A (de) |
| WO (1) | WO2003077888A2 (de) |
| ZA (1) | ZA200408412B (de) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL130602A0 (en) | 1999-06-22 | 2000-06-01 | Dexcel Ltd | Stable benzimidazole formulation |
| CA2359812C (en) | 2000-11-20 | 2004-02-10 | The Procter & Gamble Company | Pharmaceutical dosage form with multiple coatings for reduced impact of coating fractures |
| US8101209B2 (en) | 2001-10-09 | 2012-01-24 | Flamel Technologies | Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles |
| ATE407674T1 (de) | 2002-04-09 | 2008-09-15 | Flamel Tech Sa | Orale pharmazeutische formulierung in form einer wässrigen suspension von mikrokapseln zur modifizierten freisetzung von amoxicillin |
| WO2003084518A2 (fr) | 2002-04-09 | 2003-10-16 | Flamel Technologies | Suspension orale de microcapsules de principes actifs |
| FR2842735B1 (fr) * | 2002-07-26 | 2006-01-06 | Flamel Tech Sa | Microcapsules a liberation modifiee de principes actifs peu solubles pour l'administration per os |
| WO2005123134A2 (en) * | 2004-05-14 | 2005-12-29 | Cadila Healthcare Limited | A controlled release delivery system for metformin |
| DK1830814T3 (da) * | 2005-01-06 | 2009-08-03 | Cima Labs Inc | Smagsmaskeret formulering til ikke-plastificerende lægemidler |
| FR2889810A1 (fr) * | 2005-05-24 | 2007-02-23 | Flamel Technologies Sa | Forme medicamenteuse orale, microparticulaire, anti-mesurage |
| FR2881652B1 (fr) * | 2005-02-08 | 2007-05-25 | Flamel Technologies Sa | Forme pharmaceutique orale microparticulaire anti-mesuage |
| EP1888045B1 (de) * | 2005-05-24 | 2010-09-08 | Flamel Technologies | Orale pharmazeutische zusammensetzung zur behandlung einer cox-2-vermittelten erkrankung |
| WO2006131790A2 (en) * | 2005-06-09 | 2006-12-14 | Flamel Technologies | Oral ribavirin pharmaceutical composition |
| WO2006133733A1 (en) | 2005-06-13 | 2006-12-21 | Flamel Technologies | Oral dosage form comprising an antimisuse system |
| FR2892937B1 (fr) * | 2005-11-10 | 2013-04-05 | Flamel Tech Sa | Forme pharmaceutique orale microparticulaire anti-mesusage |
| US8652529B2 (en) | 2005-11-10 | 2014-02-18 | Flamel Technologies | Anti-misuse microparticulate oral pharmaceutical form |
| US20090036414A1 (en) * | 2007-08-02 | 2009-02-05 | Mutual Pharmaceutical Company, Inc. | Mesalamine Formulations |
| EP2044929A1 (de) * | 2007-10-04 | 2009-04-08 | Laboratorios del Dr. Esteve S.A. | Schnell lösliche Tabletten für orale Anwendung |
| EP2044932A1 (de) * | 2007-10-04 | 2009-04-08 | Laboratorios del Dr. Esteve S.A. | Mechanische Schutzschicht für feste Darreichungsformen |
| CN102170874A (zh) | 2008-08-06 | 2011-08-31 | 高思福斯中心（控股）有限公司 | 治疗精神病学障碍的组合物和方法 |
| EP2341708B1 (de) | 2010-01-05 | 2017-03-08 | Irdeto B.V. | Rundfunkvarianten von digitalen Signalen in einem Zugangsberechtigungssystem |
| SG10201504529WA (en) * | 2010-03-09 | 2015-07-30 | Alkermes Pharma Ireland Ltd | Alcohol Resistant Enteric Pharmaceutical Compositions |
| EP2468263A1 (de) | 2010-12-23 | 2012-06-27 | Laboratorios Del. Dr. Esteve, S.A. | Komprimierte feste Darreichungsformen |
| GB201111712D0 (en) | 2011-07-08 | 2011-08-24 | Gosforth Ct Holdings Pty Ltd | Pharmaceutical compositions |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| MX365818B (es) | 2011-11-23 | 2019-05-30 | Therapeuticsmd Inc | Formulaciones y terapias de reemplazo hormonal de combinacion naturales. |
| CN102641257A (zh) * | 2012-03-31 | 2012-08-22 | 内蒙古医学院 | 阿替洛尔缓释微囊及其制备方法 |
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| US3256153A (en) * | 1963-02-08 | 1966-06-14 | Smith Kline French Lab | Method of stabilizing wax-fat coating materials and product thereof |
| GB1598458A (en) | 1977-04-01 | 1981-09-23 | Hoechst Uk Ltd | Tableting of microcapsules |
| JPS5873359A (ja) * | 1981-10-27 | 1983-05-02 | 旭化成株式会社 | 医薬錠剤の製造方法 |
| US4728512A (en) * | 1985-05-06 | 1988-03-01 | American Home Products Corporation | Formulations providing three distinct releases |
| LU85943A1 (fr) * | 1985-06-12 | 1987-01-13 | Galephar | Comprimes pharmaceutiques permettant l'administration aisee de pellets, leur preparation et leur utilisation |
| JPH0780754B2 (ja) * | 1986-08-06 | 1995-08-30 | エーザイ株式会社 | 多顆粒型持続性錠剤 |
| US5624683A (en) * | 1986-08-06 | 1997-04-29 | Eisai Co., Ltd. | Sustained-release multi-granule tablet |
| FR2606597B1 (fr) * | 1986-11-17 | 1989-01-27 | Rhone Poulenc Sante | Nouvelle composition pour l'alimentation des ruminants contenant une substance biologiquement active et sa preparation |
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| FR2821745B1 (fr) * | 2001-03-09 | 2004-07-02 | Ethypharm Lab Prod Ethiques | Granules et granules enrobes au gout masque |
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- 2002-03-18 FR FR0203336A patent/FR2837100B1/fr not_active Expired - Fee Related
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2003
- 2003-03-14 WO PCT/FR2003/000827 patent/WO2003077888A2/fr active Application Filing
- 2003-03-14 EP EP03744400A patent/EP1485071A2/de not_active Withdrawn
- 2003-03-14 AU AU2003242818A patent/AU2003242818B2/en not_active Ceased
- 2003-03-14 KR KR10-2004-7014579A patent/KR20040105773A/ko not_active Application Discontinuation
- 2003-03-14 BR BR0308487-6A patent/BR0308487A/pt not_active IP Right Cessation
- 2003-03-14 CN CNA038063026A patent/CN1642530A/zh active Pending
- 2003-03-14 MX MXPA04009010A patent/MXPA04009010A/es active IP Right Grant
- 2003-03-14 IL IL16381303A patent/IL163813A0/xx unknown
- 2003-03-14 US US10/507,886 patent/US8507003B2/en active Active
- 2003-03-14 CA CA2479057A patent/CA2479057C/fr not_active Expired - Fee Related
- 2003-03-14 JP JP2003575941A patent/JP2005527522A/ja not_active Withdrawn
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| Publication number | Publication date |
|---|---|
| IL163813A (en) | 2010-06-30 |
| IL163813A0 (en) | 2005-12-18 |
| JP2005527522A (ja) | 2005-09-15 |
| CA2479057C (fr) | 2012-02-07 |
| AU2003242818B2 (en) | 2008-12-18 |
| BR0308487A (pt) | 2005-01-18 |
| FR2837100A1 (fr) | 2003-09-19 |
| US8507003B2 (en) | 2013-08-13 |
| WO2003077888A2 (fr) | 2003-09-25 |
| FR2837100B1 (fr) | 2004-07-23 |
| AU2003242818A1 (en) | 2003-09-29 |
| CN1642530A (zh) | 2005-07-20 |
| KR20040105773A (ko) | 2004-12-16 |
| WO2003077888A3 (fr) | 2004-04-15 |
| CA2479057A1 (fr) | 2003-09-25 |
| EP1485071A2 (de) | 2004-12-15 |
| MXPA04009010A (es) | 2004-11-26 |
| US20050266078A1 (en) | 2005-12-01 |
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