ZA200407590B - Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha-4 intergrins - Google Patents
Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha-4 intergrins Download PDFInfo
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- ZA200407590B ZA200407590B ZA200407590A ZA200407590A ZA200407590B ZA 200407590 B ZA200407590 B ZA 200407590B ZA 200407590 A ZA200407590 A ZA 200407590A ZA 200407590 A ZA200407590 A ZA 200407590A ZA 200407590 B ZA200407590 B ZA 200407590B
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- compound
- diethylamino
- phenylalanine
- ylcarbonyloxy
- pyrimidin
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- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/50—Three nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38302002P | 2002-05-24 | 2002-05-24 |
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| ZA200407590B true ZA200407590B (en) | 2006-10-25 |
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| ZA200407590A ZA200407590B (en) | 2002-05-24 | 2003-05-27 | Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha-4 intergrins |
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| EP (1) | EP1507775B1 (ru) |
| JP (1) | JP4469715B2 (ru) |
| KR (1) | KR100978832B1 (ru) |
| CN (1) | CN1314682C (ru) |
| AT (1) | ATE419243T1 (ru) |
| AU (1) | AU2003240823C1 (ru) |
| BR (1) | BR0308881A (ru) |
| CA (1) | CA2481926C (ru) |
| DE (1) | DE60325583D1 (ru) |
| DK (1) | DK1507775T3 (ru) |
| EA (1) | EA008256B1 (ru) |
| EC (1) | ECSP045425A (ru) |
| ES (1) | ES2320436T3 (ru) |
| HK (1) | HK1072608A1 (ru) |
| IL (2) | IL164225A0 (ru) |
| MX (1) | MXPA04010995A (ru) |
| NO (1) | NO329933B1 (ru) |
| NZ (1) | NZ535504A (ru) |
| TW (1) | TWI281470B (ru) |
| UA (1) | UA76339C2 (ru) |
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| WO2006127584A1 (en) | 2005-05-20 | 2006-11-30 | Elan Pharmaceuticals, Inc. | Imidazolone phenylalanine derivatives as vla-4 antagonists |
| CA2851103A1 (en) | 2005-09-29 | 2007-04-12 | Elan Pharmaceuticals, Inc. | Carbamate compounds which inhibit leukocyte adhesion mediated by vla-4 |
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| JP2019500355A (ja) * | 2015-12-30 | 2019-01-10 | セントルイス ユニバーシティ | 汎インテグリンアンタゴニストとしてのメタ−アザ環式アミノ安息香酸誘導体 |
| PE20211866A1 (es) | 2018-10-30 | 2021-09-21 | Gilead Sciences Inc | Derivados de quinolina como inhibidores de la integrina alfa4beta7 |
| US11174256B2 (en) | 2018-10-30 | 2021-11-16 | Gilead Sciences, Inc. | Imidazopyridine derivatives |
| WO2020092401A1 (en) | 2018-10-30 | 2020-05-07 | Gilead Sciences, Inc. | COMPOUNDS FOR INHIBITION OF ALPHA 4β7 INTEGRIN |
| EP3873897B1 (en) | 2018-10-30 | 2024-08-14 | Gilead Sciences, Inc. | N-benzoyl-phenylalanine derivatives as alpha4beta7 integrin inhibitors for treating inflammatory diseases |
| CN109541237A (zh) * | 2018-12-28 | 2019-03-29 | 吴江近岸蛋白质科技有限公司 | 纤维连接蛋白的生物学活性测定方法 |
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- 2003-05-27 EP EP03731419A patent/EP1507775B1/en not_active Expired - Lifetime
- 2003-05-27 KR KR1020047018173A patent/KR100978832B1/ko not_active IP Right Cessation
- 2003-05-27 NZ NZ535504A patent/NZ535504A/en not_active IP Right Cessation
- 2003-05-27 DE DE60325583T patent/DE60325583D1/de not_active Expired - Lifetime
-
2004
- 2004-09-17 NO NO20043900A patent/NO329933B1/no not_active IP Right Cessation
- 2004-09-22 IL IL164225A patent/IL164225A/en not_active IP Right Cessation
- 2004-10-11 EC EC2004005425A patent/ECSP045425A/es unknown
-
2005
- 2005-07-15 HK HK05106028.8A patent/HK1072608A1/xx not_active IP Right Cessation
-
2006
- 2006-09-26 US US11/527,901 patent/US7427628B2/en not_active Expired - Fee Related
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