AU3420693A - Competitive inhibition of high-avidity alpha4-beta1 receptor using tripeptide ldv - Google Patents

Competitive inhibition of high-avidity alpha4-beta1 receptor using tripeptide ldv

Info

Publication number
AU3420693A
AU3420693A AU34206/93A AU3420693A AU3420693A AU 3420693 A AU3420693 A AU 3420693A AU 34206/93 A AU34206/93 A AU 34206/93A AU 3420693 A AU3420693 A AU 3420693A AU 3420693 A AU3420693 A AU 3420693A
Authority
AU
Australia
Prior art keywords
alpha4
ldv
tripeptide
avidity
competitive inhibition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU34206/93A
Inventor
Elizabeth A Wayner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fred Hutchinson Cancer Center
Original Assignee
Fred Hutchinson Cancer Research Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fred Hutchinson Cancer Research Center filed Critical Fred Hutchinson Cancer Research Center
Publication of AU3420693A publication Critical patent/AU3420693A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
AU34206/93A 1991-12-24 1992-12-23 Competitive inhibition of high-avidity alpha4-beta1 receptor using tripeptide ldv Abandoned AU3420693A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81487391A 1991-12-24 1991-12-24
US814873 1991-12-24

Publications (1)

Publication Number Publication Date
AU3420693A true AU3420693A (en) 1993-07-28

Family

ID=25216225

Family Applications (1)

Application Number Title Priority Date Filing Date
AU34206/93A Abandoned AU3420693A (en) 1991-12-24 1992-12-23 Competitive inhibition of high-avidity alpha4-beta1 receptor using tripeptide ldv

Country Status (2)

Country Link
AU (1) AU3420693A (en)
WO (1) WO1993012809A1 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995015973A1 (en) * 1993-12-06 1995-06-15 Cytel Corporation Cs-1 peptidomimetics, compositions and methods of using the same
US5821231A (en) * 1993-12-06 1998-10-13 Cytel Corporation CS-1 peptidomimetics, compositions and methods of using same
US5936065A (en) * 1993-12-06 1999-08-10 Cytel Corporation CS-1 peptidomimetics, compositions and methods of using the same
JPH09509146A (en) * 1993-12-06 1997-09-16 サイテル コーポレイション CS-1 peptide mimetics, compositions and methods of use thereof
US5770573A (en) * 1993-12-06 1998-06-23 Cytel Corporation CS-1 peptidomimetics, compositions and methods of using the same
US6306840B1 (en) * 1995-01-23 2001-10-23 Biogen, Inc. Cell adhesion inhibitors
AU758886B2 (en) * 1995-07-11 2003-04-03 Biogen Idec Ma Inc. Cell adhesion inhibitors
US6248713B1 (en) * 1995-07-11 2001-06-19 Biogen, Inc. Cell adhesion inhibitors
US6037324A (en) * 1996-01-04 2000-03-14 Leukosite, Inc. Inhibitors of MAdCAM-1-mediated interactions and methods of use therefor
US6001573A (en) * 1996-06-14 1999-12-14 Packard Bioscience B.V. Use of porphyrins as a universal label
EP0812920A1 (en) * 1996-06-14 1997-12-17 Packard Instrument B.V. Use of porphyrins in instrumental detection methods
US6239108B1 (en) 1996-07-11 2001-05-29 Biogen, Inc. Cell adhesion inhibitors
DE69737769T2 (en) 1996-07-25 2008-05-15 Biogen Idec Ma Inc., Cambridge MOLECULE MODEL FOR VLA-4 INHIBITORS
US6686350B1 (en) 1996-07-25 2004-02-03 Biogen, Inc. Cell adhesion inhibitors
EA002988B1 (en) 1998-05-28 2002-12-26 Байоджен, Инк. (R)-N-[[4-[[(2-METHYLPHENYLAMINO)CARBONYL]AMINO]PHENYL]ACETYL]-L-PROPYL-3-METHYL)-BETA-ALANINE AND ITS USE AS A CELL ADHESION INHIBITOR MEDIATED BY INTEGRIN alpha4beta1 INHIBITORS
AR035476A1 (en) 1999-01-22 2004-06-02 Elan Pharm Inc HETEROARILO AND HETEROCICLIC COMPOUNDS WITH FUSIONED RING, WHICH INHIBIT THE ADHESION OF LEUKOCYTES THROUGH VLA-4, PHARMACEUTICAL COMPOSITIONS, THE USE OF THE SAME FOR THE MANUFACTURE OF A MEDICINAL PRODUCT AND A BIOLOGICAL METHOD 4
CA2359115C (en) 1999-01-22 2011-06-21 Elan Pharmaceuticals, Inc. Acyl derivatives which treat vla-4 related disorders
US6436904B1 (en) 1999-01-25 2002-08-20 Elan Pharmaceuticals, Inc. Compounds which inhibit leukocyte adhesion mediated by VLA-4
SK287075B6 (en) 1999-08-13 2009-11-05 Biogen Idec Ma Inc. Cell adhesion inhibitors and pharmaceutical compositions comprising them
US6875743B1 (en) 2000-11-28 2005-04-05 Biogen, Inc. Cell adhesion inhibitors
TWI281470B (en) 2002-05-24 2007-05-21 Elan Pharm Inc Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins
TW200307671A (en) 2002-05-24 2003-12-16 Elan Pharm Inc Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins
US7196112B2 (en) 2004-07-16 2007-03-27 Biogen Idec Ma Inc. Cell adhesion inhibitors
DK1940826T3 (en) 2005-09-29 2011-04-18 Elan Pharm Inc Pyrimidinylamide compounds that inhibit leukocyte adhesion mediated through BLA-4
EP1940827B1 (en) 2005-09-29 2011-03-16 Elan Pharmaceuticals Inc. Carbamate compounds which inhibit leukocyte adhesion mediated by vla-4
JP5135235B2 (en) 2006-02-27 2013-02-06 エラン ファーマシューティカルズ，インコーポレイテッド Pyrimidinylsulfonamide compounds that inhibit leukocyte adhesion mediated by VAL-4
WO2010126914A1 (en) 2009-04-27 2010-11-04 Elan Pharmaceuticals, Inc. Pyridinone antagonists of alpha-4 integrins

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL113261A (en) * 1989-09-01 1996-10-16 Hutchinson Fred Cancer Res Inhibition by peptides of lymphocyte adherence to vascular endothelium utilizing an extracellular matrix receptor-ligand interaction and pharmaceutical compositions containing said peptides

Also Published As

Publication number Publication date
WO1993012809A1 (en) 1993-07-08

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