ZA200402265B - Antibody inhibitors of GDF-8 and uses thereof - Google Patents
Antibody inhibitors of GDF-8 and uses thereof Download PDFInfo
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- ZA200402265B ZA200402265B ZA200402265A ZA200402265A ZA200402265B ZA 200402265 B ZA200402265 B ZA 200402265B ZA 200402265 A ZA200402265 A ZA 200402265A ZA 200402265 A ZA200402265 A ZA 200402265A ZA 200402265 B ZA200402265 B ZA 200402265B
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
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- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Molecular Biology (AREA)
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- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Nutrition Science (AREA)
- Biomedical Technology (AREA)
- Child & Adolescent Psychology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32452801P | 2001-09-26 | 2001-09-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200402265B true ZA200402265B (en) | 2007-03-28 |
Family
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
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| ZA200402265A ZA200402265B (en) | 2001-09-26 | 2004-03-23 | Antibody inhibitors of GDF-8 and uses thereof |
| ZA200606082A ZA200606082B (en) | 2001-09-26 | 2006-07-21 | Antibody inhibitors of GDF-8 and BMP-11 and uses thereof |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200606082A ZA200606082B (en) | 2001-09-26 | 2006-07-21 | Antibody inhibitors of GDF-8 and BMP-11 and uses thereof |
Country Status (16)
| Country | Link |
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| US (5) | US7320789B2 (zh) |
| EP (2) | EP2316851A1 (zh) |
| JP (2) | JP4452077B2 (zh) |
| AU (1) | AU2002347773B2 (zh) |
| BR (1) | BR0212809A (zh) |
| CA (1) | CA2469230C (zh) |
| DK (1) | DK1438068T3 (zh) |
| ES (1) | ES2481165T3 (zh) |
| HK (1) | HK1064284A1 (zh) |
| MX (1) | MXPA04002834A (zh) |
| NO (1) | NO336528B1 (zh) |
| NZ (1) | NZ532034A (zh) |
| PL (1) | PL374221A1 (zh) |
| PT (1) | PT1438068E (zh) |
| WO (1) | WO2003027248A2 (zh) |
| ZA (2) | ZA200402265B (zh) |
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| TWI329129B (en) | 2001-02-08 | 2010-08-21 | Wyeth Corp | Modified and stabilized gdf propeptides and uses thereof |
| US7320789B2 (en) | 2001-09-26 | 2008-01-22 | Wyeth | Antibody inhibitors of GDF-8 and uses thereof |
| BR0307907A2 (pt) | 2002-02-21 | 2011-07-05 | Wyeth Corp | gasp1: proteìna contendo domìnio de folistatina |
| US7572763B2 (en) * | 2002-02-21 | 2009-08-11 | Wyeth | Follistatin domain containing proteins |
| US20040138118A1 (en) * | 2002-09-16 | 2004-07-15 | Neil Wolfman | Metalloprotease activation of myostatin, and methods of modulating myostatin activity |
| AR047392A1 (es) * | 2002-10-22 | 2006-01-18 | Wyeth Corp | Neutralizacion de anticuerpos contra gdf 8 y su uso para tales fines |
| US20040223966A1 (en) * | 2002-10-25 | 2004-11-11 | Wolfman Neil M. | ActRIIB fusion polypeptides and uses therefor |
| NZ541253A (en) | 2002-12-20 | 2010-03-26 | Amgen Inc | Peptide binding agents which inhibit myostatin |
| AU2004245025A1 (en) * | 2003-06-02 | 2004-12-16 | Wyeth | Use of myostatin (GDF8) inhibitors in conjunction with corticosteroids for treating neuromuscular disorders |
| JP2007535912A (ja) * | 2003-12-31 | 2007-12-13 | シェーリング−プラウ・リミテッド | 中和エピトープベースの増殖増強性ワクチン |
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| RU2451082C2 (ru) * | 2004-08-27 | 2012-05-20 | Вайет Рисёрч Айрлэнд Лимитед | Производство полипептидов |
| US7300773B2 (en) | 2004-08-27 | 2007-11-27 | Wyeth Research Ireland Limited | Production of TNFR-Ig |
| TWI384069B (zh) * | 2004-08-27 | 2013-02-01 | Pfizer Ireland Pharmaceuticals | 多胜肽之製法 |
| TWI374935B (en) | 2004-08-27 | 2012-10-21 | Pfizer Ireland Pharmaceuticals | Production of α-abeta |
| AU2005323087A1 (en) | 2004-12-30 | 2006-07-13 | Schering-Plough Pty. Limited | Neutralizing epitope-based growth enhancing vaccine |
| NZ538097A (en) * | 2005-02-07 | 2006-07-28 | Ovita Ltd | Method and compositions for improving wound healing |
| MX2007011405A (es) * | 2005-03-23 | 2007-10-11 | Wyeth Corp | Deteccion de una respuesta inmune para agentes moduladores de crecimiento y la diferenciacion del factor 8 (gdf 8). |
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| CA2538208A1 (en) * | 2005-05-04 | 2006-11-04 | Universite Laval | Modulation of myostatin and use thereof in cell transplantation-based treatment of muscle disease |
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| JP2009067798A (ja) | 2009-04-02 |
| WO2003027248A3 (en) | 2003-05-30 |
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| US7731961B1 (en) | 2010-06-08 |
| PT1438068E (pt) | 2014-07-24 |
| PL374221A1 (en) | 2005-10-03 |
| HK1064284A1 (zh) | 2005-01-28 |
| US9505831B2 (en) | 2016-11-29 |
| US20120107928A1 (en) | 2012-05-03 |
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| WO2003027248A2 (en) | 2003-04-03 |
| MXPA04002834A (es) | 2005-09-28 |
| EP1438068A2 (en) | 2004-07-21 |
| CA2469230C (en) | 2017-02-21 |
| CA2469230A1 (en) | 2003-04-03 |
| BR0212809A (pt) | 2005-12-13 |
| AU2002347773B2 (en) | 2008-03-13 |
| US20150024484A1 (en) | 2015-01-22 |
| ES2481165T3 (es) | 2014-07-29 |
| US7320789B2 (en) | 2008-01-22 |
| EP1438068A4 (en) | 2005-11-16 |
| JP4452077B2 (ja) | 2010-04-21 |
| US20030138422A1 (en) | 2003-07-24 |
| WO2003027248A8 (en) | 2004-04-22 |
| NZ532034A (en) | 2006-06-30 |
| DK1438068T3 (da) | 2014-06-30 |
| NO336528B1 (no) | 2015-09-21 |
| JP2005510212A (ja) | 2005-04-21 |
| US8710202B2 (en) | 2014-04-29 |
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