ZA200307474B - CCR5 antagonists useful for treating AIDS. - Google Patents
CCR5 antagonists useful for treating AIDS. Download PDFInfo
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- ZA200307474B ZA200307474B ZA200307474A ZA200307474A ZA200307474B ZA 200307474 B ZA200307474 B ZA 200307474B ZA 200307474 A ZA200307474 A ZA 200307474A ZA 200307474 A ZA200307474 A ZA 200307474A ZA 200307474 B ZA200307474 B ZA 200307474B
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- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
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Landscapes
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| WO2003004487A1 (fr) | 2001-07-02 | 2003-01-16 | Astrazeneca Ab | Derives de piperidine convenant comme modulateurs de l'activite du recepteur de la chimiokine |
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| SE0300957D0 (sv) | 2003-04-01 | 2003-04-01 | Astrazeneca Ab | Chemical compounds |
| JP4757802B2 (ja) * | 2003-11-03 | 2011-08-24 | シェーリング コーポレイション | ケモカインレセプターの阻害剤として有用なビピペリジニル誘導体 |
| JP2007520556A (ja) * | 2004-02-05 | 2007-07-26 | シェーリング コーポレイション | Ｃｃｒ３アンタゴニストとして有用なピペリジン誘導体 |
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| NZ550370A (en) * | 2004-04-13 | 2009-09-25 | Incyte Corp | Piperazinylpiperidine derivatives as chemokine receptor antagonists |
| RU2409565C2 (ru) | 2004-09-13 | 2011-01-20 | Оно Фармасьютикал Ко., Лтд. | Азотистые гетероциклические производные и лекарственные средства, содержащие их в качестве активного ингредиента |
| WO2006071875A1 (fr) | 2004-12-29 | 2006-07-06 | Millennium Pharmaceuticals, Inc. | Composes utilises comme antagonistes des recepteurs de la chemokine |
| US7635698B2 (en) | 2004-12-29 | 2009-12-22 | Millennium Pharmaceuticals, Inc. | Compounds useful as chemokine receptor antagonists |
| CA2594114A1 (fr) * | 2005-01-06 | 2006-07-13 | Schering Corporation | Synthese d'antagonistes des recepteurs ccr5 |
| EP1836190A2 (fr) * | 2005-01-06 | 2007-09-26 | Schering Corporation | Preparation de sels pharmaceutiques de composes piperazine |
| AR055313A1 (es) | 2005-02-23 | 2007-08-15 | Schering Corp | Derivados piperidinil piperidina utiles como inhibidores de receptores de quimioquinas. proceso de obtencion y composiciones farmaceuticas |
| EP1858887A1 (fr) * | 2005-02-23 | 2007-11-28 | Schering Corporation | Dérivés de pipéridine pipéridinyle servant d inhibiteurs de récepteurs chémokines |
| KR20080037655A (ko) | 2005-07-21 | 2008-04-30 | 아스트라제네카 아베 | 신규 피페리딘 유도체 |
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| MX2009006881A (es) * | 2006-12-22 | 2009-07-03 | Schering Corp | Procesos para la preparacion de antagonistas del receptor ccr-5 utilizando compuestos de 1-ciclopropan-sulfonil-piperidinilo 4-sustituido. |
| EP2259772A2 (fr) * | 2008-02-29 | 2010-12-15 | Schering Corporation | Antagonistes de ccr5 en tant que produits prophylactiques pour prévenir une infection par le vih et procédés d'inhibition de la transmission de celle-ci |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5368854A (en) | 1992-08-20 | 1994-11-29 | Schering Corporation | Use of IL-10 to treat inflammatory bowel disease |
| AU6135294A (en) | 1993-02-12 | 1994-08-29 | Merck & Co., Inc. | Piperazine derivatives as hiv protease inhibitors |
| US5889006A (en) | 1995-02-23 | 1999-03-30 | Schering Corporation | Muscarinic antagonists |
| IL117149A0 (en) | 1995-02-23 | 1996-06-18 | Schering Corp | Muscarinic antagonists |
| DE69629961T2 (de) | 1995-06-07 | 2004-07-22 | Kimberly-Clark Worldwide, Inc., Neenah | Inhibierung von Exoproteinen in absorbiereden Produkten |
| NZ321575A (en) | 1995-10-30 | 1999-05-28 | Janssen Pharmaceutica Nv | 1-(1,2-disubstituted piperidinyl)-4- substituted piperazine derivatives |
| TW531537B (en) | 1995-12-27 | 2003-05-11 | Janssen Pharmaceutica Nv | 1-(1,2-disubstituted piperidinyl)-4-substituted piperidine derivatives |
| US5952349A (en) | 1996-07-10 | 1999-09-14 | Schering Corporation | Muscarinic antagonists for treating memory loss |
| US5977138A (en) | 1996-08-15 | 1999-11-02 | Schering Corporation | Ether muscarinic antagonists |
| EP1003514A4 (fr) | 1997-07-25 | 2000-10-11 | Merck & Co Inc | Amines cycliques modulant l'activite des recepteurs de chimiokines |
| US6066636A (en) | 1998-06-30 | 2000-05-23 | Schering Corporation | Muscarinic antagonists |
| EP1013276A1 (fr) * | 1998-12-23 | 2000-06-28 | Pfizer Inc. | Aminoazacycloalcanes comme modulateurs de CCR5 |
| WO2000066559A1 (fr) | 1999-05-04 | 2000-11-09 | Schering Corporation | Derives de piperidine faisant office d'antagonistes ccr5 |
| SK286641B6 (sk) * | 1999-05-04 | 2009-03-05 | Schering Corporation | Piperazínové deriváty užitočné ako CCR5 antagonisty, farmaceutické prípravky s ich obsahom a ich použitie |
| EP1591444B1 (fr) * | 2001-03-29 | 2010-04-28 | Schering Corporation | Antagonistes de la CCR5 utilisés pour la traitement de la CIDA. |
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2002
- 2002-03-27 EP EP05009882A patent/EP1591444B1/fr not_active Expired - Lifetime
- 2002-03-27 US US10/107,940 patent/US6720325B2/en not_active Expired - Lifetime
- 2002-03-27 JP JP2002577819A patent/JP4248251B2/ja not_active Expired - Fee Related
- 2002-03-27 CZ CZ20032636A patent/CZ20032636A3/cs unknown
- 2002-03-27 DK DK02725381T patent/DK1373256T3/da active
- 2002-03-27 KR KR1020037012565A patent/KR100613528B1/ko not_active IP Right Cessation
- 2002-03-27 AT AT05009882T patent/ATE466009T1/de not_active IP Right Cessation
- 2002-03-27 PL PL02364560A patent/PL364560A1/xx not_active IP Right Cessation
- 2002-03-27 AT AT02725381T patent/ATE299139T1/de active
- 2002-03-27 AU AU2002255947A patent/AU2002255947B8/en not_active Ceased
- 2002-03-27 ES ES05009882T patent/ES2342942T3/es not_active Expired - Lifetime
- 2002-03-27 PE PE2002000251A patent/PE20020996A1/es not_active Application Discontinuation
- 2002-03-27 WO PCT/US2002/009491 patent/WO2002079194A1/fr active IP Right Grant
- 2002-03-27 BR BR0208398-1A patent/BR0208398A/pt not_active IP Right Cessation
- 2002-03-27 RU RU2003131879/04A patent/RU2316553C2/ru not_active IP Right Cessation
- 2002-03-27 HU HU0400349A patent/HUP0400349A3/hu unknown
- 2002-03-27 EP EP02725381A patent/EP1373256B1/fr not_active Expired - Lifetime
- 2002-03-27 NZ NZ527768A patent/NZ527768A/en unknown
- 2002-03-27 CA CA002442227A patent/CA2442227C/fr not_active Expired - Fee Related
- 2002-03-27 DE DE60236218T patent/DE60236218D1/de not_active Expired - Lifetime
- 2002-03-27 IL IL15755102A patent/IL157551A0/xx not_active IP Right Cessation
- 2002-03-27 PT PT02725381T patent/PT1373256E/pt unknown
- 2002-03-27 SI SI200230169T patent/SI1373256T1/sl unknown
- 2002-03-27 DE DE60204951T patent/DE60204951T2/de not_active Expired - Lifetime
- 2002-03-27 AR ARP020101142A patent/AR033452A1/es unknown
- 2002-03-27 CN CNB028076540A patent/CN100519554C/zh not_active Expired - Fee Related
- 2002-03-27 ES ES02725381T patent/ES2242856T3/es not_active Expired - Lifetime
- 2002-03-27 SK SK1196-2003A patent/SK287521B6/sk not_active IP Right Cessation
- 2002-03-27 MX MXPA03008853A patent/MXPA03008853A/es active IP Right Grant
- 2002-03-28 TW TW091106166A patent/TWI237638B/zh active
- 2002-03-28 MY MYPI20021140A patent/MY128609A/en unknown
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2003
- 2003-09-25 ZA ZA200307474A patent/ZA200307474B/en unknown
- 2003-09-26 NO NO20034311A patent/NO326349B1/no not_active IP Right Cessation
-
2004
- 2004-01-05 HK HK04100050A patent/HK1057363A1/xx not_active IP Right Cessation
- 2004-02-06 US US10/773,521 patent/US6900211B2/en not_active Expired - Fee Related
- 2004-10-21 US US10/970,216 patent/US7008946B2/en not_active Expired - Fee Related
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2005
- 2005-02-17 US US11/059,785 patent/US7060701B2/en not_active Expired - Fee Related
- 2005-10-14 US US11/250,247 patent/US7098213B2/en not_active Expired - Fee Related
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2006
- 2006-03-21 HK HK06103528.9A patent/HK1083505A1/xx not_active IP Right Cessation
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2007
- 2007-10-26 JP JP2007279663A patent/JP2008074862A/ja not_active Withdrawn
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