ZA200306733B - Metalloproteinase inhibitors. - Google Patents

Metalloproteinase inhibitors. Download PDF

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Publication number
ZA200306733B
ZA200306733B ZA200306733A ZA200306733A ZA200306733B ZA 200306733 B ZA200306733 B ZA 200306733B ZA 200306733 A ZA200306733 A ZA 200306733A ZA 200306733 A ZA200306733 A ZA 200306733A ZA 200306733 B ZA200306733 B ZA 200306733B
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ZA
South Africa
Prior art keywords
alkyl
compound
formula
heteroaryl
pharmaceutically acceptable
Prior art date
Application number
ZA200306733A
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English (en)
Inventor
Matti Lepistoe
Magnus Munck Af Rosenschoeld
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Astrazeneca Ab
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Publication of ZA200306733B publication Critical patent/ZA200306733B/en

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    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
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    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
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  • Immunology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Otolaryngology (AREA)
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ZA200306733A 2001-03-15 2003-08-28 Metalloproteinase inhibitors. ZA200306733B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0100903A SE0100903D0 (sv) 2001-03-15 2001-03-15 Compounds

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ZA200306733B true ZA200306733B (en) 2004-11-29

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ZA200306733A ZA200306733B (en) 2001-03-15 2003-08-28 Metalloproteinase inhibitors.
ZA200306738A ZA200306738B (en) 2001-03-15 2003-08-28 Metalloproteinase inhibitors.

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US (2) US20040116486A1 (sk)
EP (2) EP1370538A1 (sk)
JP (2) JP2004523582A (sk)
KR (2) KR20030082988A (sk)
CN (2) CN1509274A (sk)
AR (1) AR035444A1 (sk)
AU (1) AU2002237633B2 (sk)
BR (2) BR0207985A (sk)
CA (2) CA2444526A1 (sk)
CZ (2) CZ20032498A3 (sk)
EE (2) EE200300452A (sk)
HU (2) HUP0400193A3 (sk)
IL (2) IL157650A0 (sk)
IS (2) IS6945A (sk)
MX (2) MXPA03008187A (sk)
MY (1) MY129188A (sk)
NO (2) NO20034032L (sk)
NZ (2) NZ528108A (sk)
PL (2) PL364705A1 (sk)
RU (2) RU2003127731A (sk)
SE (1) SE0100903D0 (sk)
SK (2) SK10912003A3 (sk)
UA (2) UA74624C2 (sk)
WO (2) WO2002074749A1 (sk)
ZA (2) ZA200306733B (sk)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
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CO5300399A1 (es) 2000-02-25 2003-07-31 Astrazeneca Ab Heterocicliocs que contienen nitrogeno, proceso para su preparacion y composiciones farmaceuticas que los contienen
US7005439B2 (en) * 2000-06-20 2006-02-28 Astrazeneca Ab Compounds
SE0100903D0 (sv) * 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
SE0100902D0 (sv) 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
DE60234028D1 (de) 2001-05-25 2009-11-26 Bristol Myers Squibb Co Hydantion-derivate als hemmer von matrix-metalloproteinasen
SE0103710D0 (sv) 2001-11-07 2001-11-07 Astrazeneca Ab Compounds
MY131170A (en) * 2002-03-28 2007-07-31 Nissan Chemical Ind Ltd Therapeutic agent for glomerular disease
SE0202539D0 (sv) * 2002-08-27 2002-08-27 Astrazeneca Ab Compounds
SE0202692D0 (sv) * 2002-09-11 2002-09-11 Astrazeneca Ab Compounds
GB0221246D0 (en) * 2002-09-13 2002-10-23 Astrazeneca Ab Compounds
FR2845000B1 (fr) * 2002-09-27 2005-05-27 Oreal Utilisation d'un compose heterocyclique ou de l'un de ses sels pour stimuler ou induire la pousse des cheveux et/ou freiner leur chute
US7648992B2 (en) 2004-07-05 2010-01-19 Astrazeneca Ab Hydantoin derivatives for the treatment of obstructive airway diseases
SE0401762D0 (sv) * 2004-07-05 2004-07-05 Astrazeneca Ab Novel compounds
SE0401763D0 (sv) * 2004-07-05 2004-07-05 Astrazeneca Ab Compounds
NZ553258A (en) 2004-08-19 2011-02-25 Quest Pharmaceutical Services Qps 5-[3-(4-Benzyloxyphenylthio)-fur-2-yl]-imidazolidin-2,4-dione and analogues as inhibitors of macrophage elastase
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