ZA200302190B - Spiro-pyrimidine-2, 4, 6-trione metalloproteinase inhibitors. - Google Patents
Spiro-pyrimidine-2, 4, 6-trione metalloproteinase inhibitors. Download PDFInfo
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- ZA200302190B ZA200302190B ZA200302190A ZA200302190A ZA200302190B ZA 200302190 B ZA200302190 B ZA 200302190B ZA 200302190 A ZA200302190 A ZA 200302190A ZA 200302190 A ZA200302190 A ZA 200302190A ZA 200302190 B ZA200302190 B ZA 200302190B
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Classifications
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Gynecology & Obstetrics (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cardiology (AREA)
- Pregnancy & Childbirth (AREA)
- Hematology (AREA)
- Virology (AREA)
- Obesity (AREA)
- Psychology (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24338900P | 2000-10-26 | 2000-10-26 |
Publications (1)
Publication Number | Publication Date |
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ZA200302190B true ZA200302190B (en) | 2004-04-28 |
Family
ID=22918584
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200302190A ZA200302190B (en) | 2000-10-26 | 2003-03-19 | Spiro-pyrimidine-2, 4, 6-trione metalloproteinase inhibitors. |
Country Status (32)
Country | Link |
---|---|
EP (1) | EP1332146A2 (sk) |
JP (1) | JP2004518635A (sk) |
KR (1) | KR20040004412A (sk) |
CN (1) | CN1501937A (sk) |
AP (1) | AP2001002318A0 (sk) |
AR (1) | AR035069A1 (sk) |
AU (1) | AU2002210813A1 (sk) |
BG (1) | BG107653A (sk) |
BR (1) | BR0114913A (sk) |
CA (1) | CA2425283A1 (sk) |
CZ (1) | CZ20031083A3 (sk) |
EA (1) | EA005762B1 (sk) |
EC (1) | ECSP034567A (sk) |
EE (1) | EE200300196A (sk) |
GT (1) | GT200100213A (sk) |
HN (1) | HN2001000244A (sk) |
HR (1) | HRP20030332A2 (sk) |
HU (1) | HUP0301577A3 (sk) |
IL (1) | IL154948A0 (sk) |
IS (1) | IS6762A (sk) |
MA (1) | MA26957A1 (sk) |
MX (1) | MXPA03003735A (sk) |
NO (1) | NO20031853L (sk) |
OA (1) | OA12529A (sk) |
PA (1) | PA8531401A1 (sk) |
PE (1) | PE20020589A1 (sk) |
PL (1) | PL366201A1 (sk) |
SK (1) | SK4972003A3 (sk) |
SV (1) | SV2003000705A (sk) |
TN (1) | TNSN01149A1 (sk) |
WO (1) | WO2002034753A2 (sk) |
ZA (1) | ZA200302190B (sk) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DOP2002000332A (es) | 2001-02-14 | 2002-08-30 | Warner Lambert Co | Inhibidores de piridina de metaloproteinasas de la matriz |
DOP2002000333A (es) | 2001-02-14 | 2002-09-30 | Warner Lambert Co | Derivados de acido isoftalico como inhibidores de metaloproteinasas de la matriz |
EP1368323B1 (en) | 2001-02-14 | 2010-06-30 | Warner-Lambert Company LLC | Pyrimidine matrix metalloproteinase inhibitors |
PA8539501A1 (es) | 2001-02-14 | 2002-09-30 | Warner Lambert Co | Compuestos triazolo como inhibidores de mmp |
ES2231708T3 (es) | 2001-02-14 | 2005-05-16 | Warner-Lambert Company Llc | Benzotiadicinas inhibidoras de metaloproteinasa de matriz. |
US6924276B2 (en) | 2001-09-10 | 2005-08-02 | Warner-Lambert Company | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors |
WO2003032999A1 (en) | 2001-10-12 | 2003-04-24 | Warner-Lambert Company Llc | Alkyne matrix metalloproteinase inhibitors |
US6962922B2 (en) | 2001-10-12 | 2005-11-08 | Warner-Lambert Company Llc | Alkynylated quinazoline compounds |
US6894057B2 (en) | 2002-03-08 | 2005-05-17 | Warner-Lambert Company | Oxo-azabicyclic compounds |
WO2003091252A1 (en) * | 2002-04-25 | 2003-11-06 | Bristol-Myers Squibb Company | Spirobarbituric acid derivatives useful as inhibitors of matrix metalloproteases |
WO2003091258A1 (en) * | 2002-04-26 | 2003-11-06 | Pfizer Products Inc. | N-substituted-heteroaryloxy-aryl-spiro-pyrimidine-2,4,6-trione metalloproteinase inhibitors |
WO2003091259A1 (en) * | 2002-04-26 | 2003-11-06 | Pfizer Products Inc. | Triaryl-oxy-aryl-spiro-pyrimidine-2, 4, 6-trione metalloproteinase inhibitors |
AU2003250466A1 (en) | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | 3-isoquinolinone derivatives as matrix metalloproteinase inhiitors |
AU2003253150A1 (en) | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Chromone derivatives as matrix metalloproteinase inhibitors |
JP2006504665A (ja) | 2002-08-13 | 2006-02-09 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | マトリックスメタロプロテイナーゼ阻害剤としてのアザイソキノリン誘導体 |
AU2003249540A1 (en) | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Fused bicyclic metalloproteinase inhibitors |
PA8578101A1 (es) | 2002-08-13 | 2004-05-07 | Warner Lambert Co | Derivados de heterobiarilo como inhibidores de metaloproteinasa de la matriz |
MXPA05001603A (es) * | 2002-08-13 | 2005-04-25 | Warner Lambert Co | Derivados monociclicos como inhibidores de metaloproteinasa de matriz. |
AU2003253186A1 (en) | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Fused tetrahydropyridine derivatives as matrix metalloproteinase inhibitors |
BR0313385A (pt) | 2002-08-13 | 2005-06-14 | Warner Lambert Co | Derivados de pirimidina-2,4-diona como inibidores de metaloproteinase da matriz |
WO2004014908A1 (en) | 2002-08-13 | 2004-02-19 | Warner-Lambert Company Llc | Heterobicylcic metalloproteinase inhibitors |
AU2003250470A1 (en) | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Pyrimidinone fused bicyclic metalloproteinase inhibitors |
US7208490B2 (en) | 2002-10-07 | 2007-04-24 | Pharmacia & Upjohn Company Llc | Tricyclic tetrahydroquinoline antibacterial agents |
GB0223249D0 (en) * | 2002-10-08 | 2002-11-13 | Amersham Plc | Improved imaging agents |
WO2004084903A1 (en) * | 2003-03-27 | 2004-10-07 | F. Hoffmann-La Roche Ag | Use of a trioxopyrimidine for the treatment and prevention of ocular pathologic angiogenesis |
WO2004084902A1 (en) * | 2003-03-28 | 2004-10-07 | F. Hoffmann-La Roche Ag | Use of a trioxopyrimidine for the treatment of chronic wounds |
FR2858232B1 (fr) * | 2003-07-29 | 2006-03-03 | Pierre Potier | Utilisation d'un derive de biguanide pour proteger la peau des radiations uvb |
RU2402329C2 (ru) * | 2004-04-01 | 2010-10-27 | Юниверсите Де-Льеж | Применение триоксопиримидина для лечения и предупреждения воспалительных заболеваний бронхов |
DOP2006000268A (es) | 2005-12-22 | 2007-07-31 | Pfizer Prod Inc | Agentes antibacterianos |
US8153166B2 (en) * | 2006-06-08 | 2012-04-10 | Chih-Hsiung Lin | Composition for prophylaxis or treatment of urinary system infection and method thereof |
CN102285934B (zh) * | 2009-01-08 | 2013-08-14 | 四川大学 | 螺环二烯酮衍生物及其制备方法和用途 |
US9428505B2 (en) * | 2012-12-10 | 2016-08-30 | Chugai Seiyaku Kabushiki Kaisha | Hydantoin derivative |
KR101594506B1 (ko) * | 2014-03-20 | 2016-02-17 | 한국화학연구원 | 골 관련 질환 치료용 조성물 |
BR112016003511B8 (pt) | 2014-06-09 | 2023-10-03 | Chugai Pharmaceutical Co Ltd | Composição farmacêutica que contém derivados de hidantoína e uso dos mesmos |
AU2019387367A1 (en) | 2018-11-30 | 2021-06-10 | Nuvation Bio Inc. | Diarylhydantoin compounds and methods of use thereof |
CN110092790B (zh) * | 2019-06-11 | 2020-07-24 | 东北农业大学 | 一种生物碱类化合物及其制备方法和应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3714093A (en) * | 1970-05-19 | 1973-01-30 | American Home Prod | Spiro [heterocycloalkyl-2'(1'h)-quinazoline]-4'(3'h)-ones |
TR199903148T2 (xx) * | 1997-06-21 | 2000-04-21 | Roche Diagnostics Gmbh | Antimetastatik ve antit�m�r etkinli�i olan barbit�rik asit t�revleri. |
US6265578B1 (en) * | 1999-02-12 | 2001-07-24 | Hoffmann-La Roche Inc. | Pyrimidine-2,4,6-triones |
PA8498701A1 (es) * | 1999-08-12 | 2002-08-26 | Pfizer Prod Inc | Pirimidina-2,4,6-trionas inhibidores de metaloproteinasas |
-
2001
- 2001-10-23 CZ CZ20031083A patent/CZ20031083A3/cs unknown
- 2001-10-23 IL IL15494801A patent/IL154948A0/xx unknown
- 2001-10-23 WO PCT/IB2001/001986 patent/WO2002034753A2/en not_active Application Discontinuation
- 2001-10-23 EA EA200300306A patent/EA005762B1/ru not_active IP Right Cessation
- 2001-10-23 HU HU0301577A patent/HUP0301577A3/hu unknown
- 2001-10-23 AP APAP/P/2001/002318A patent/AP2001002318A0/en unknown
- 2001-10-23 BR BR0114913-0A patent/BR0114913A/pt not_active IP Right Cessation
- 2001-10-23 JP JP2002537743A patent/JP2004518635A/ja not_active Withdrawn
- 2001-10-23 CN CNA018179231A patent/CN1501937A/zh active Pending
- 2001-10-23 EP EP01978721A patent/EP1332146A2/en not_active Withdrawn
- 2001-10-23 AU AU2002210813A patent/AU2002210813A1/en not_active Abandoned
- 2001-10-23 EE EEP200300196A patent/EE200300196A/xx unknown
- 2001-10-23 PL PL01366201A patent/PL366201A1/xx not_active Application Discontinuation
- 2001-10-23 MX MXPA03003735A patent/MXPA03003735A/es unknown
- 2001-10-23 OA OA1200300123A patent/OA12529A/en unknown
- 2001-10-23 CA CA002425283A patent/CA2425283A1/en not_active Abandoned
- 2001-10-23 KR KR10-2003-7005753A patent/KR20040004412A/ko not_active Application Discontinuation
- 2001-10-23 SK SK497-2003A patent/SK4972003A3/sk unknown
- 2001-10-24 AR ARP010104977A patent/AR035069A1/es unknown
- 2001-10-24 HN HN2001000244A patent/HN2001000244A/es unknown
- 2001-10-25 PE PE2001001060A patent/PE20020589A1/es not_active Application Discontinuation
- 2001-10-25 TN TNTNSN01149A patent/TNSN01149A1/fr unknown
- 2001-10-25 GT GT200100213A patent/GT200100213A/es unknown
- 2001-10-25 SV SV2001000705A patent/SV2003000705A/es unknown
- 2001-10-26 PA PA20018531401A patent/PA8531401A1/es unknown
-
2003
- 2003-03-19 ZA ZA200302190A patent/ZA200302190B/en unknown
- 2003-03-20 BG BG107653A patent/BG107653A/bg unknown
- 2003-03-27 IS IS6762A patent/IS6762A/is unknown
- 2003-04-22 MA MA27117A patent/MA26957A1/fr unknown
- 2003-04-24 NO NO20031853A patent/NO20031853L/no not_active Application Discontinuation
- 2003-04-25 EC EC2003004567A patent/ECSP034567A/es unknown
- 2003-04-28 HR HR20030332A patent/HRP20030332A2/hr not_active Application Discontinuation
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