ZA200301978B - Retinoids for the treatment of emphysema. - Google Patents

Retinoids for the treatment of emphysema. Download PDF

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Publication number
ZA200301978B
ZA200301978B ZA200301978A ZA200301978A ZA200301978B ZA 200301978 B ZA200301978 B ZA 200301978B ZA 200301978 A ZA200301978 A ZA 200301978A ZA 200301978 A ZA200301978 A ZA 200301978A ZA 200301978 B ZA200301978 B ZA 200301978B
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South Africa
Prior art keywords
tetramethyl
mmol
tetrahydro
ethyl acetate
naphthalen
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ZA200301978A
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English (en)
Inventor
Jean-Marc Lapierre
David Mark Rotstein
Eric Brian Sjogren
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Hoffmann La Roche
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Publication of ZA200301978B publication Critical patent/ZA200301978B/en

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    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
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