ZA200209638B - Compositions and methods for the treatment of cancer. - Google Patents
Compositions and methods for the treatment of cancer. Download PDFInfo
- Publication number
- ZA200209638B ZA200209638B ZA200209638A ZA200209638A ZA200209638B ZA 200209638 B ZA200209638 B ZA 200209638B ZA 200209638 A ZA200209638 A ZA 200209638A ZA 200209638 A ZA200209638 A ZA 200209638A ZA 200209638 B ZA200209638 B ZA 200209638B
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- ZA
- South Africa
- Prior art keywords
- pharmaceutically acceptable
- solvate
- clathrate
- hydrate
- salt
- Prior art date
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- DVPVGSLIUJPOCJ-XXRQFBABSA-N x1j761618a Chemical compound OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.C([C@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(=O)CN(C)C)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21.C([C@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(=O)CN(C)C)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21 DVPVGSLIUJPOCJ-XXRQFBABSA-N 0.000 description 1
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Classifications
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A—HUMAN NECESSITIES
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Animal Behavior & Ethology (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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AR (1) | AR029084A1 (pt) |
AT (1) | ATE322266T1 (pt) |
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TW (1) | TWI289449B (pt) |
WO (1) | WO2001087307A2 (pt) |
ZA (1) | ZA200209638B (pt) |
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KR101851470B1 (ko) | 2016-12-19 | 2018-06-11 | 한림대학교 산학협력단 | 퀘세틴이 함유된 유방암 예방 및 치료를 위한 약제학적 조성물 |
WO2018183917A1 (en) | 2017-03-30 | 2018-10-04 | Taxis Pharmaceuticals, Inc. | Synthetic processes and synthetic intermediates |
US10537585B2 (en) | 2017-12-18 | 2020-01-21 | Dexcel Pharma Technologies Ltd. | Compositions comprising dexamethasone |
Family Cites Families (7)
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JPS6019790A (ja) | 1983-07-14 | 1985-01-31 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体 |
US5422344A (en) * | 1990-05-08 | 1995-06-06 | The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services | Method of treating retroviral infections in mammals |
WO1992014455A1 (en) | 1991-02-14 | 1992-09-03 | The Rockefeller University | METHOD FOR CONTROLLING ABNORMAL CONCENTRATION TNF α IN HUMAN TISSUES |
US5629327A (en) | 1993-03-01 | 1997-05-13 | Childrens Hospital Medical Center Corp. | Methods and compositions for inhibition of angiogenesis |
US5643915A (en) | 1995-06-06 | 1997-07-01 | Andrulis Pharmaceuticals Corp. | Treatment of ischemia/reperfusion injury with thalidomide alone or in combination with other therapies |
US5654312A (en) | 1995-06-07 | 1997-08-05 | Andrulis Pharmaceuticals | Treatment of inflammatory and/or autoimmune dermatoses with thalidomide alone or in combination with other agents |
GB9523493D0 (en) * | 1995-11-16 | 1996-01-17 | British Biotech Pharm | Preparation of allyl succinate derivatives and starting materials therefore |
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2001
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- 2001-05-10 ES ES01935373T patent/ES2258084T3/es not_active Expired - Lifetime
- 2001-05-10 DE DE60118571T patent/DE60118571T2/de not_active Expired - Lifetime
- 2001-05-10 DK DK01935373T patent/DK1307197T3/da active
- 2001-05-10 BR BR0110877-8A patent/BR0110877A/pt active Search and Examination
- 2001-05-10 AU AU6147401A patent/AU6147401A/xx active Pending
- 2001-05-10 WO PCT/US2001/015327 patent/WO2001087307A2/en active IP Right Grant
- 2001-05-10 AU AU2001261474A patent/AU2001261474B2/en not_active Ceased
- 2001-05-10 NZ NZ522767A patent/NZ522767A/en not_active IP Right Cessation
- 2001-05-10 CA CA2408707A patent/CA2408707C/en not_active Expired - Fee Related
- 2001-05-10 AT AT01935373T patent/ATE322266T1/de active
- 2001-05-10 KR KR1020027015443A patent/KR100790589B1/ko not_active IP Right Cessation
- 2001-05-10 MX MXPA02011218A patent/MXPA02011218A/es active IP Right Grant
- 2001-05-10 EP EP01935373A patent/EP1307197B1/en not_active Expired - Lifetime
- 2001-05-10 PT PT01935373T patent/PT1307197E/pt unknown
- 2001-05-14 US US09/853,617 patent/US7435726B2/en not_active Expired - Fee Related
- 2001-05-15 AR ARP010102298A patent/AR029084A1/es unknown
- 2001-06-26 TW TW090111620A patent/TWI289449B/zh active
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2002
- 2002-11-27 ZA ZA200209638A patent/ZA200209638B/en unknown
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2003
- 2003-08-29 HK HK03106199A patent/HK1054502A1/xx not_active IP Right Cessation
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2005
- 2005-03-09 US US11/074,849 patent/US20050148524A1/en not_active Abandoned
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HK1054502A1 (en) | 2003-12-05 |
EP1307197A2 (en) | 2003-05-07 |
JP5409981B2 (ja) | 2014-02-05 |
US7435726B2 (en) | 2008-10-14 |
ES2258084T3 (es) | 2006-08-16 |
CA2408707C (en) | 2010-04-13 |
MXPA02011218A (es) | 2004-08-19 |
WO2001087307A2 (en) | 2001-11-22 |
DE60118571T2 (de) | 2007-02-01 |
AU2001261474B2 (en) | 2006-03-09 |
BR0110877A (pt) | 2003-03-11 |
TWI289449B (en) | 2007-11-11 |
ATE322266T1 (de) | 2006-04-15 |
AR029084A1 (es) | 2003-06-04 |
KR100790589B1 (ko) | 2008-01-02 |
NZ522767A (en) | 2004-07-30 |
PT1307197E (pt) | 2006-08-31 |
EP1307197B1 (en) | 2006-04-05 |
US20050148524A1 (en) | 2005-07-07 |
WO2001087307A3 (en) | 2002-07-25 |
AU6147401A (en) | 2001-11-26 |
KR20030025922A (ko) | 2003-03-29 |
US20020035090A1 (en) | 2002-03-21 |
DE60118571D1 (de) | 2006-05-18 |
JP2003533484A (ja) | 2003-11-11 |
CA2408707A1 (en) | 2001-11-22 |
DK1307197T3 (da) | 2006-07-03 |
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