ZA200208039B - Proteins deposited onto sparingly soluble biocompatible particles for controlled protein release into a biological environment from a polymer matrix. - Google Patents

Proteins deposited onto sparingly soluble biocompatible particles for controlled protein release into a biological environment from a polymer matrix. Download PDF

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Publication number
ZA200208039B
ZA200208039B ZA200208039A ZA200208039A ZA200208039B ZA 200208039 B ZA200208039 B ZA 200208039B ZA 200208039 A ZA200208039 A ZA 200208039A ZA 200208039 A ZA200208039 A ZA 200208039A ZA 200208039 B ZA200208039 B ZA 200208039B
Authority
ZA
South Africa
Prior art keywords
protein
particle
poly
drug delivery
delivery system
Prior art date
Application number
ZA200208039A
Other languages
English (en)
Inventor
Chung Shih
Gaylen M Zentner
Ai-Zhi Piao
Original Assignee
Macromed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Macromed Inc filed Critical Macromed Inc
Publication of ZA200208039B publication Critical patent/ZA200208039B/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ZA200208039A 2000-04-07 2002-10-07 Proteins deposited onto sparingly soluble biocompatible particles for controlled protein release into a biological environment from a polymer matrix. ZA200208039B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19570000P 2000-04-07 2000-04-07
US09/827,100 US6998137B2 (en) 2000-04-07 2001-04-05 Proteins deposited onto sparingly soluble biocompatible particles for controlled protein release into a biological environment from a polymer matrix

Publications (1)

Publication Number Publication Date
ZA200208039B true ZA200208039B (en) 2004-02-04

Family

ID=26891244

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200208039A ZA200208039B (en) 2000-04-07 2002-10-07 Proteins deposited onto sparingly soluble biocompatible particles for controlled protein release into a biological environment from a polymer matrix.

Country Status (19)

Country Link
US (1) US6998137B2 (xx)
EP (1) EP1267838B1 (xx)
JP (2) JP4731088B2 (xx)
KR (1) KR100923817B1 (xx)
CN (1) CN100518814C (xx)
AT (1) ATE526947T1 (xx)
AU (1) AU2001251389A1 (xx)
BR (1) BRPI0110319B1 (xx)
CA (1) CA2405030C (xx)
CY (1) CY1112294T1 (xx)
DK (1) DK1267838T3 (xx)
ES (1) ES2374224T3 (xx)
HK (1) HK1057705A1 (xx)
IL (2) IL152131A0 (xx)
MX (1) MXPA02009790A (xx)
NZ (1) NZ521994A (xx)
PT (1) PT1267838E (xx)
WO (1) WO2001076558A1 (xx)
ZA (1) ZA200208039B (xx)

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Also Published As

Publication number Publication date
PT1267838E (pt) 2012-01-11
NZ521994A (en) 2003-08-29
JP2011026336A (ja) 2011-02-10
KR20030009425A (ko) 2003-01-29
IL152131A0 (en) 2003-05-29
EP1267838B1 (en) 2011-10-05
MXPA02009790A (es) 2003-06-19
CY1112294T1 (el) 2015-12-09
BR0110319A (pt) 2003-07-29
BRPI0110319B1 (pt) 2016-09-27
JP4731088B2 (ja) 2011-07-20
CN100518814C (zh) 2009-07-29
KR100923817B1 (ko) 2009-10-27
US20020015737A1 (en) 2002-02-07
US6998137B2 (en) 2006-02-14
EP1267838A4 (en) 2009-01-14
CA2405030A1 (en) 2001-10-18
EP1267838A1 (en) 2003-01-02
CN1430504A (zh) 2003-07-16
JP5193262B2 (ja) 2013-05-08
IL152131A (en) 2010-11-30
WO2001076558A1 (en) 2001-10-18
HK1057705A1 (en) 2004-04-16
ATE526947T1 (de) 2011-10-15
CA2405030C (en) 2011-01-25
JP2004507450A (ja) 2004-03-11
DK1267838T3 (da) 2012-01-23
ES2374224T3 (es) 2012-02-14
AU2001251389A1 (en) 2001-10-23

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