ATE526947T1 - Proteine aufgebracht auf geringlösliche biokompatible partikel zur kontrollierten freisetzung der proteine in eine biologische umgebung aus einer polymermatrix - Google Patents
Proteine aufgebracht auf geringlösliche biokompatible partikel zur kontrollierten freisetzung der proteine in eine biologische umgebung aus einer polymermatrixInfo
- Publication number
- ATE526947T1 ATE526947T1 AT01924765T AT01924765T ATE526947T1 AT E526947 T1 ATE526947 T1 AT E526947T1 AT 01924765 T AT01924765 T AT 01924765T AT 01924765 T AT01924765 T AT 01924765T AT E526947 T1 ATE526947 T1 AT E526947T1
- Authority
- AT
- Austria
- Prior art keywords
- proteins
- protein
- particle
- controlled release
- polymer matrix
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 7
- 108090000623 proteins and genes Proteins 0.000 title abstract 7
- 239000002245 particle Substances 0.000 title abstract 5
- 239000011159 matrix material Substances 0.000 title abstract 3
- 238000013270 controlled release Methods 0.000 title 1
- 229920000642 polymer Polymers 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 230000008021 deposition Effects 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 238000001179 sorption measurement Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19570000P | 2000-04-07 | 2000-04-07 | |
| US09/827,100 US6998137B2 (en) | 2000-04-07 | 2001-04-05 | Proteins deposited onto sparingly soluble biocompatible particles for controlled protein release into a biological environment from a polymer matrix |
| PCT/US2001/011217 WO2001076558A1 (en) | 2000-04-07 | 2001-04-06 | Proteins deposited onto sparingly soluble biocompatible particles for controlled protein release into a biological environment from a polymer matrix |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE526947T1 true ATE526947T1 (de) | 2011-10-15 |
Family
ID=26891244
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01924765T ATE526947T1 (de) | 2000-04-07 | 2001-04-06 | Proteine aufgebracht auf geringlösliche biokompatible partikel zur kontrollierten freisetzung der proteine in eine biologische umgebung aus einer polymermatrix |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6998137B2 (de) |
| EP (1) | EP1267838B1 (de) |
| JP (2) | JP4731088B2 (de) |
| KR (1) | KR100923817B1 (de) |
| CN (1) | CN100518814C (de) |
| AT (1) | ATE526947T1 (de) |
| AU (1) | AU2001251389A1 (de) |
| BR (1) | BRPI0110319B1 (de) |
| CA (1) | CA2405030C (de) |
| CY (1) | CY1112294T1 (de) |
| DK (1) | DK1267838T3 (de) |
| ES (1) | ES2374224T3 (de) |
| HK (1) | HK1057705A1 (de) |
| IL (2) | IL152131A0 (de) |
| MX (1) | MXPA02009790A (de) |
| NZ (1) | NZ521994A (de) |
| PT (1) | PT1267838E (de) |
| WO (1) | WO2001076558A1 (de) |
| ZA (1) | ZA200208039B (de) |
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| CA2452194A1 (en) * | 2001-09-11 | 2003-03-20 | Smart Drug Systems Inc | Sustained release pharmaceutical compositions comprising a silicone support material |
| US7247609B2 (en) | 2001-12-18 | 2007-07-24 | Universitat Zurich | Growth factor modified protein matrices for tissue engineering |
| EP1864681A1 (de) | 2001-12-18 | 2007-12-12 | Eidgenössische Technische Hochschule Zürich | Wachstumsfaktormodifizierte Proteinmatrizes zur Geweberekonstruktion |
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| DE69614685T2 (de) * | 1995-06-07 | 2002-06-27 | Alkermes Inc | Mittel zur verzögerten freisetzung von menschlichem wachstumshormon |
| EP0959873B1 (de) * | 1996-12-20 | 2006-03-01 | ALZA Corporation | Gelzusammensetzungen und verfahren |
| US6113947A (en) * | 1997-06-13 | 2000-09-05 | Genentech, Inc. | Controlled release microencapsulated NGF formulation |
| US6201072B1 (en) * | 1997-10-03 | 2001-03-13 | Macromed, Inc. | Biodegradable low molecular weight triblock poly(lactide-co- glycolide) polyethylene glycol copolymers having reverse thermal gelation properties |
| KR20010030891A (ko) * | 1997-10-03 | 2001-04-16 | 마크로메드 인코퍼레이션 | 가역적 열 겔화 성질을 갖는 생분해성 저분자량 트리블럭폴리(락티드-코-글리콜리드) 폴리에틸렌 글리콜 공중합체 |
| US6287588B1 (en) * | 1999-04-29 | 2001-09-11 | Macromed, Inc. | Agent delivering system comprised of microparticle and biodegradable gel with an improved releasing profile and methods of use thereof |
| US6711968B2 (en) * | 2002-08-02 | 2004-03-30 | Visteon Global Technologies, Inc. | Axle differential assembly |
-
2001
- 2001-04-05 US US09/827,100 patent/US6998137B2/en not_active Expired - Lifetime
- 2001-04-06 AT AT01924765T patent/ATE526947T1/de active
- 2001-04-06 PT PT01924765T patent/PT1267838E/pt unknown
- 2001-04-06 DK DK01924765.9T patent/DK1267838T3/da active
- 2001-04-06 WO PCT/US2001/011217 patent/WO2001076558A1/en active IP Right Grant
- 2001-04-06 EP EP01924765A patent/EP1267838B1/de not_active Expired - Lifetime
- 2001-04-06 NZ NZ521994A patent/NZ521994A/en not_active IP Right Cessation
- 2001-04-06 CA CA2405030A patent/CA2405030C/en not_active Expired - Fee Related
- 2001-04-06 IL IL15213101A patent/IL152131A0/xx unknown
- 2001-04-06 BR BRPI0110319A patent/BRPI0110319B1/pt not_active IP Right Cessation
- 2001-04-06 KR KR1020027013405A patent/KR100923817B1/ko not_active IP Right Cessation
- 2001-04-06 AU AU2001251389A patent/AU2001251389A1/en not_active Abandoned
- 2001-04-06 ES ES01924765T patent/ES2374224T3/es not_active Expired - Lifetime
- 2001-04-06 MX MXPA02009790A patent/MXPA02009790A/es active IP Right Grant
- 2001-04-06 JP JP2001574076A patent/JP4731088B2/ja not_active Expired - Fee Related
- 2001-04-06 CN CNB018099823A patent/CN100518814C/zh not_active Expired - Fee Related
-
2002
- 2002-10-06 IL IL152131A patent/IL152131A/en not_active IP Right Cessation
- 2002-10-07 ZA ZA200208039A patent/ZA200208039B/en unknown
-
2004
- 2004-01-19 HK HK04100051.2A patent/HK1057705A1/xx not_active IP Right Cessation
-
2010
- 2010-10-01 JP JP2010223933A patent/JP5193262B2/ja not_active Expired - Lifetime
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2011
- 2011-12-22 CY CY20111101281T patent/CY1112294T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP5193262B2 (ja) | 2013-05-08 |
| KR100923817B1 (ko) | 2009-10-27 |
| IL152131A0 (en) | 2003-05-29 |
| AU2001251389A1 (en) | 2001-10-23 |
| KR20030009425A (ko) | 2003-01-29 |
| IL152131A (en) | 2010-11-30 |
| CA2405030C (en) | 2011-01-25 |
| ES2374224T3 (es) | 2012-02-14 |
| JP2011026336A (ja) | 2011-02-10 |
| CN100518814C (zh) | 2009-07-29 |
| ZA200208039B (en) | 2004-02-04 |
| EP1267838B1 (de) | 2011-10-05 |
| BRPI0110319B1 (pt) | 2016-09-27 |
| CA2405030A1 (en) | 2001-10-18 |
| PT1267838E (pt) | 2012-01-11 |
| US20020015737A1 (en) | 2002-02-07 |
| EP1267838A1 (de) | 2003-01-02 |
| NZ521994A (en) | 2003-08-29 |
| CN1430504A (zh) | 2003-07-16 |
| BR0110319A (pt) | 2003-07-29 |
| JP2004507450A (ja) | 2004-03-11 |
| DK1267838T3 (da) | 2012-01-23 |
| CY1112294T1 (el) | 2015-12-09 |
| WO2001076558A1 (en) | 2001-10-18 |
| EP1267838A4 (de) | 2009-01-14 |
| HK1057705A1 (en) | 2004-04-16 |
| MXPA02009790A (es) | 2003-06-19 |
| US6998137B2 (en) | 2006-02-14 |
| JP4731088B2 (ja) | 2011-07-20 |
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