ATE153535T1 - Tgf-beta zusammensetzung zum herbeiführen von knochenwachstum - Google Patents

Tgf-beta zusammensetzung zum herbeiführen von knochenwachstum

Info

Publication number
ATE153535T1
ATE153535T1 AT94906606T AT94906606T ATE153535T1 AT E153535 T1 ATE153535 T1 AT E153535T1 AT 94906606 T AT94906606 T AT 94906606T AT 94906606 T AT94906606 T AT 94906606T AT E153535 T1 ATE153535 T1 AT E153535T1
Authority
AT
Austria
Prior art keywords
induring
tgf
bone growth
beta composition
beta
Prior art date
Application number
AT94906606T
Other languages
English (en)
Inventor
Arthur J Ammann
Steven L Beck
Tue H Nguyen
Boonsri Ongpipattanakul
Christopher G Rudman
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE153535T1 publication Critical patent/ATE153535T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1841—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
AT94906606T 1993-01-12 1994-01-11 Tgf-beta zusammensetzung zum herbeiführen von knochenwachstum ATE153535T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US336593A 1993-01-12 1993-01-12

Publications (1)

Publication Number Publication Date
ATE153535T1 true ATE153535T1 (de) 1997-06-15

Family

ID=21705523

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94906606T ATE153535T1 (de) 1993-01-12 1994-01-11 Tgf-beta zusammensetzung zum herbeiführen von knochenwachstum

Country Status (10)

Country Link
EP (1) EP0679097B1 (de)
JP (1) JP3347144B2 (de)
AT (1) ATE153535T1 (de)
AU (1) AU671721B2 (de)
CA (1) CA2151486A1 (de)
DE (1) DE69403439T2 (de)
DK (1) DK0679097T3 (de)
ES (1) ES2105641T3 (de)
GR (1) GR3024277T3 (de)
WO (1) WO1994015653A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5503558A (en) * 1993-11-12 1996-04-02 Mcgill University Osseointegration promoting implant composition, implant assembly and method therefor
DE19529223A1 (de) * 1995-08-09 1997-02-13 Boehringer Mannheim Gmbh Verwendung von Plasminogenaktivatoren zum lokalen Knochenaufbau
US5776193A (en) 1995-10-16 1998-07-07 Orquest, Inc. Bone grafting matrix
US6902584B2 (en) 1995-10-16 2005-06-07 Depuy Spine, Inc. Bone grafting matrix
EP0957943B2 (de) † 1997-02-07 2008-11-26 Stryker Corporation Matrixlose osteogene vorrichtungen und implantate und verfahren zu deren verwendung
US7041641B2 (en) * 1997-03-20 2006-05-09 Stryker Corporation Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects
US20010016646A1 (en) 1998-03-20 2001-08-23 David C. Rueger Osteogenic devices and methods of use thereof for repair of endochondral bone, osteochondral and chondral defects
NL1008582C2 (nl) * 1998-01-05 1999-07-06 Vrije Universiteit Botmateriaal.
US20030147860A1 (en) 2002-02-07 2003-08-07 Marchosky J. Alexander Compositions and methods for forming and strengthening bone
JP2002519155A (ja) * 1998-07-02 2002-07-02 スティヒティング・スケルトル・ティシュー・エンジニアリング・グループ・アムステルダム 抗微生物性ペプチドを有する骨セメント
EP0992251A1 (de) * 1998-10-07 2000-04-12 Isotis B.V. Vorrichtung zur Knochenbehandlung eines Knochersatzmaterials
IT1302534B1 (it) 1998-12-21 2000-09-05 Fidia Advanced Biopolymers Srl Composizioni iniettabili, biocompatibili e biodegradabili comprendentialmeno un derivato dell'acido ialuronico, cellule condrogeniche, per
WO2000054797A2 (en) * 1999-03-17 2000-09-21 Novartis Ag Pharmaceutical compositions comprising tgf-beta
EP1203074A4 (de) 1999-06-29 2003-09-10 J Alexander Marchosky Zusammensetzungen und verfahren zur bildung und festigung von knochen
US20020114795A1 (en) * 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
DK1448246T4 (en) 2001-11-19 2015-12-21 Scil Technology Gmbh Homogeneously coated device with osteoinductive and osteoconductive properties
TW200400062A (en) 2002-04-03 2004-01-01 Mathys Medizinaltechnik Ag Kneadable, pliable bone replacement material
US7166133B2 (en) 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
US7018361B2 (en) 2002-06-14 2006-03-28 Baxter International Inc. Infusion pump
AU2003256300A1 (en) 2002-06-24 2004-01-06 New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Complexed-acidic-phospholipid-collagen composites for bone induction
WO2004011053A1 (en) * 2002-07-31 2004-02-05 Dentsply International Inc. Bone repair putty comprising porous particulate and carrier gel
US8876532B2 (en) 2002-07-31 2014-11-04 Dentsply International Inc. Bone repair putty
CN100522241C (zh) 2002-09-10 2009-08-05 Scil技术股份有限公司 在低氧气浓度下用骨诱导蛋白包被的金属植入物
EP1462126A1 (de) * 2003-03-28 2004-09-29 BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH Verbesserte osteoinduktive Materialien
US7534264B2 (en) 2004-01-28 2009-05-19 Ultradent Products, Inc. Delivery system for bone growth promoting material
US8372419B2 (en) 2004-03-10 2013-02-12 Scil Technology Gmbh Coated implants, their manufacturing and use thereof
EP1880731A1 (de) * 2006-07-18 2008-01-23 BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH Menschlicher Wachstums und Differenzierungsfaktor GDF-5
ES2666650T3 (es) * 2006-12-29 2018-05-07 OstéoQC Inc. Métodos para alterar el crecimiento óseo mediante la administración de antagonista o agonista de sost o wise
EP2308518A4 (de) * 2008-06-30 2013-04-24 Univ Tokyo Knochendefektfüller, der keinen knochenwachstumsfaktor adsorbiert und dessen wirkung nicht unterdrückt
CA2798710C (en) 2010-05-11 2019-08-27 Venkat R. Garigapati Organophosphorous, multivalent metal compounds, & polymer adhesive interpenetrating network compositions & methods
EP2529764A1 (de) 2011-05-31 2012-12-05 Curasan AG Biologisch degradierbares kompositmaterial
US20140066837A1 (en) 2012-07-26 2014-03-06 Ronald L. Moy Skin care compositions and methods
US10688222B2 (en) 2016-11-21 2020-06-23 Warsaw Orthopedic, Inc. Lyophilized moldable implants containing an oxysterol

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5108436A (en) * 1988-09-29 1992-04-28 Collagen Corporation Implant fixation
IE61346B1 (en) * 1988-11-02 1994-11-02 Genentech Inc A permeable material to fit around the teeth or gums of a mammal
US4976736A (en) * 1989-04-28 1990-12-11 Interpore International Coated biomaterials and methods for making same
US5158934A (en) * 1989-09-01 1992-10-27 Genentech, Inc. Method of inducing bone growth using TGF-β
US5071655A (en) * 1990-01-12 1991-12-10 Baylink David J Pharmaceutical combination for treatment of bone-wasting diseases
US5208219A (en) * 1991-02-14 1993-05-04 Celtrix Pharmaceuticals Inc. Method for inducing bone growth
DE4121043A1 (de) * 1991-06-26 1993-01-07 Merck Patent Gmbh Knochenersatzmaterial mit fgf
US5270300A (en) * 1991-09-06 1993-12-14 Robert Francis Shaw Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone

Also Published As

Publication number Publication date
DE69403439D1 (de) 1997-07-03
WO1994015653A1 (en) 1994-07-21
GR3024277T3 (en) 1997-10-31
EP0679097B1 (de) 1997-05-28
JPH08505548A (ja) 1996-06-18
AU6026294A (en) 1994-08-15
CA2151486A1 (en) 1994-07-21
ES2105641T3 (es) 1997-10-16
EP0679097A1 (de) 1995-11-02
JP3347144B2 (ja) 2002-11-20
AU671721B2 (en) 1996-09-05
DE69403439T2 (de) 1997-10-23
DK0679097T3 (da) 1997-12-22

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UEP Publication of translation of european patent specification