ES2105641T3 - Formulacion del factor de crecimiento de transformacion beta que provoca el crecimiento de los huesos. - Google Patents
Formulacion del factor de crecimiento de transformacion beta que provoca el crecimiento de los huesos.Info
- Publication number
- ES2105641T3 ES2105641T3 ES94906606T ES94906606T ES2105641T3 ES 2105641 T3 ES2105641 T3 ES 2105641T3 ES 94906606 T ES94906606 T ES 94906606T ES 94906606 T ES94906606 T ES 94906606T ES 2105641 T3 ES2105641 T3 ES 2105641T3
- Authority
- ES
- Spain
- Prior art keywords
- formulation
- growth
- bones
- causes
- growth factor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1841—Transforming growth factor [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
Abstract
SE PROPORCIONA UNA FORMULACION PARA TRANSFORMAR EL FACTOR DE CRECIMIENTO {BE} QUE CONTIENE FOSFATO TRICALCICO, PREFERIBLEMENTE EN LA FORMA DE PARTICULAS COMO GRANULOS. LA FORMULACION CONTIENE OPCIONALMENTE UN POLIMERO COMO AMILOPECTINA PARA MEJORAR LA CONSISTENCIA DE LA FORMULACION.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US336593A | 1993-01-12 | 1993-01-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2105641T3 true ES2105641T3 (es) | 1997-10-16 |
Family
ID=21705523
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94906606T Expired - Lifetime ES2105641T3 (es) | 1993-01-12 | 1994-01-11 | Formulacion del factor de crecimiento de transformacion beta que provoca el crecimiento de los huesos. |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0679097B1 (es) |
JP (1) | JP3347144B2 (es) |
AT (1) | ATE153535T1 (es) |
AU (1) | AU671721B2 (es) |
CA (1) | CA2151486A1 (es) |
DE (1) | DE69403439T2 (es) |
DK (1) | DK0679097T3 (es) |
ES (1) | ES2105641T3 (es) |
GR (1) | GR3024277T3 (es) |
WO (1) | WO1994015653A1 (es) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5503558A (en) * | 1993-11-12 | 1996-04-02 | Mcgill University | Osseointegration promoting implant composition, implant assembly and method therefor |
DE19529223A1 (de) * | 1995-08-09 | 1997-02-13 | Boehringer Mannheim Gmbh | Verwendung von Plasminogenaktivatoren zum lokalen Knochenaufbau |
US6902584B2 (en) | 1995-10-16 | 2005-06-07 | Depuy Spine, Inc. | Bone grafting matrix |
US5776193A (en) | 1995-10-16 | 1998-07-07 | Orquest, Inc. | Bone grafting matrix |
DE69814352T3 (de) † | 1997-02-07 | 2009-08-13 | Stryker Corp., Kalamazoo | Matrixlose osteogene vorrichtungen und implantate und verfahren zu deren verwendung |
US7041641B2 (en) * | 1997-03-20 | 2006-05-09 | Stryker Corporation | Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects |
US20010016646A1 (en) | 1998-03-20 | 2001-08-23 | David C. Rueger | Osteogenic devices and methods of use thereof for repair of endochondral bone, osteochondral and chondral defects |
NL1008582C2 (nl) * | 1998-01-05 | 1999-07-06 | Vrije Universiteit | Botmateriaal. |
US20030147860A1 (en) | 2002-02-07 | 2003-08-07 | Marchosky J. Alexander | Compositions and methods for forming and strengthening bone |
WO2000001427A1 (en) * | 1998-07-02 | 2000-01-13 | Stichting Skeletal Tissue Engineering Group Amsterdam | Bone cement with antimicrobial peptides |
EP0992251A1 (en) * | 1998-10-07 | 2000-04-12 | Isotis B.V. | Device for tissue engineering a bone equivalent |
IT1302534B1 (it) | 1998-12-21 | 2000-09-05 | Fidia Advanced Biopolymers Srl | Composizioni iniettabili, biocompatibili e biodegradabili comprendentialmeno un derivato dell'acido ialuronico, cellule condrogeniche, per |
EP1161257A2 (en) | 1999-03-17 | 2001-12-12 | Novartis AG | Pharmaceutical compositions comprising tgf-beta |
WO2001000792A1 (en) | 1999-06-29 | 2001-01-04 | Marchosky J Alexander | Compositions and methods for forming and strengthening bone |
US20020114795A1 (en) * | 2000-12-22 | 2002-08-22 | Thorne Kevin J. | Composition and process for bone growth and repair |
BR0214275A (pt) | 2001-11-19 | 2004-09-21 | Scil Technology Gmbh | Dispositivo tendo propriedades osteocondutora e osteoindutora |
TW200400062A (en) | 2002-04-03 | 2004-01-01 | Mathys Medizinaltechnik Ag | Kneadable, pliable bone replacement material |
US7166133B2 (en) | 2002-06-13 | 2007-01-23 | Kensey Nash Corporation | Devices and methods for treating defects in the tissue of a living being |
US7018361B2 (en) | 2002-06-14 | 2006-03-28 | Baxter International Inc. | Infusion pump |
WO2004000232A2 (en) | 2002-06-24 | 2003-12-31 | New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery | Complexed-acidic-phospholipid-collagen composites for bone induction |
WO2004011053A1 (en) * | 2002-07-31 | 2004-02-05 | Dentsply International Inc. | Bone repair putty comprising porous particulate and carrier gel |
US8876532B2 (en) | 2002-07-31 | 2014-11-04 | Dentsply International Inc. | Bone repair putty |
WO2004024199A1 (en) | 2002-09-10 | 2004-03-25 | Scil Technology Gmbh | Metal implant coated under reduced oxygen concentration with osteoinductive protein |
EP1462126A1 (en) * | 2003-03-28 | 2004-09-29 | BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH | Improved Osteoinductive Materials |
US7534264B2 (en) | 2004-01-28 | 2009-05-19 | Ultradent Products, Inc. | Delivery system for bone growth promoting material |
EP1737734B1 (en) | 2004-03-10 | 2010-08-18 | Scil Technology GmbH | Coated implants, their manufacturing and use thereof |
EP1880731A1 (en) * | 2006-07-18 | 2008-01-23 | BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH | Human growth and differentiation factor GDF-5 |
EP2144613B1 (en) * | 2006-12-29 | 2018-03-21 | OstéoQC Inc. | Methods of altering bone growth by administration of sost or wise antagonist or agonist |
US20110166672A1 (en) * | 2008-06-30 | 2011-07-07 | The University Of Tokyo | Bone defect filler not adsorbing bone growth factor and not inhibiting the activity of the same |
CA3048850A1 (en) | 2010-05-11 | 2011-11-17 | Howmedica Osteonics Corp. | Organophosphorous, multivalent metal compounds, & polymer adhesive interpenetrating network compositions & methods |
EP2529764A1 (de) | 2011-05-31 | 2012-12-05 | Curasan AG | Biologisch degradierbares kompositmaterial |
US20140066837A1 (en) | 2012-07-26 | 2014-03-06 | Ronald L. Moy | Skin care compositions and methods |
US10688222B2 (en) | 2016-11-21 | 2020-06-23 | Warsaw Orthopedic, Inc. | Lyophilized moldable implants containing an oxysterol |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5108436A (en) * | 1988-09-29 | 1992-04-28 | Collagen Corporation | Implant fixation |
IE61346B1 (en) * | 1988-11-02 | 1994-11-02 | Genentech Inc | A permeable material to fit around the teeth or gums of a mammal |
US4976736A (en) * | 1989-04-28 | 1990-12-11 | Interpore International | Coated biomaterials and methods for making same |
US5158934A (en) * | 1989-09-01 | 1992-10-27 | Genentech, Inc. | Method of inducing bone growth using TGF-β |
US5071655A (en) * | 1990-01-12 | 1991-12-10 | Baylink David J | Pharmaceutical combination for treatment of bone-wasting diseases |
US5208219A (en) * | 1991-02-14 | 1993-05-04 | Celtrix Pharmaceuticals Inc. | Method for inducing bone growth |
DE4121043A1 (de) * | 1991-06-26 | 1993-01-07 | Merck Patent Gmbh | Knochenersatzmaterial mit fgf |
US5270300A (en) * | 1991-09-06 | 1993-12-14 | Robert Francis Shaw | Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone |
-
1994
- 1994-01-11 DE DE69403439T patent/DE69403439T2/de not_active Expired - Lifetime
- 1994-01-11 JP JP51630794A patent/JP3347144B2/ja not_active Expired - Lifetime
- 1994-01-11 CA CA002151486A patent/CA2151486A1/en not_active Abandoned
- 1994-01-11 AU AU60262/94A patent/AU671721B2/en not_active Expired
- 1994-01-11 WO PCT/US1994/000409 patent/WO1994015653A1/en active Search and Examination
- 1994-01-11 DK DK94906606.2T patent/DK0679097T3/da active
- 1994-01-11 EP EP94906606A patent/EP0679097B1/en not_active Expired - Lifetime
- 1994-01-11 AT AT94906606T patent/ATE153535T1/de active
- 1994-01-11 ES ES94906606T patent/ES2105641T3/es not_active Expired - Lifetime
-
1997
- 1997-07-30 GR GR970401926T patent/GR3024277T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE69403439T2 (de) | 1997-10-23 |
CA2151486A1 (en) | 1994-07-21 |
GR3024277T3 (en) | 1997-10-31 |
AU671721B2 (en) | 1996-09-05 |
EP0679097A1 (en) | 1995-11-02 |
ATE153535T1 (de) | 1997-06-15 |
AU6026294A (en) | 1994-08-15 |
WO1994015653A1 (en) | 1994-07-21 |
EP0679097B1 (en) | 1997-05-28 |
DE69403439D1 (de) | 1997-07-03 |
JPH08505548A (ja) | 1996-06-18 |
DK0679097T3 (da) | 1997-12-22 |
JP3347144B2 (ja) | 2002-11-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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