DE69407404D1 - Feste zubereitung mit hoher freisetzung, ihre herstellung und verwendung - Google Patents

Feste zubereitung mit hoher freisetzung, ihre herstellung und verwendung

Info

Publication number
DE69407404D1
DE69407404D1 DE69407404T DE69407404T DE69407404D1 DE 69407404 D1 DE69407404 D1 DE 69407404D1 DE 69407404 T DE69407404 T DE 69407404T DE 69407404 T DE69407404 T DE 69407404T DE 69407404 D1 DE69407404 D1 DE 69407404D1
Authority
DE
Germany
Prior art keywords
solid preparation
production
high release
active agent
dissolved
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69407404T
Other languages
English (en)
Other versions
DE69407404T2 (de
Inventor
Jean Paul Remon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universiteit Gent
Original Assignee
Universiteit Gent
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universiteit Gent filed Critical Universiteit Gent
Publication of DE69407404D1 publication Critical patent/DE69407404D1/de
Application granted granted Critical
Publication of DE69407404T2 publication Critical patent/DE69407404T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
DE69407404T 1993-04-22 1994-04-21 Feste zubereitung mit hoher freisetzung, ihre herstellung und verwendung Expired - Fee Related DE69407404T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BE9300407A BE1006990A5 (nl) 1993-04-22 1993-04-22 Werkwijze en samenstelling om een aktief bestanddeel in een vaste toedieningsvorm te brengen.
PCT/BE1994/000029 WO1994023700A1 (en) 1993-04-22 1994-04-21 High release solid preparation, preparation and use thereof

Publications (2)

Publication Number Publication Date
DE69407404D1 true DE69407404D1 (de) 1998-01-29
DE69407404T2 DE69407404T2 (de) 1998-07-02

Family

ID=3886999

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69407404T Expired - Fee Related DE69407404T2 (de) 1993-04-22 1994-04-21 Feste zubereitung mit hoher freisetzung, ihre herstellung und verwendung

Country Status (12)

Country Link
US (1) US6368634B1 (de)
EP (1) EP0695172B1 (de)
JP (1) JP2960169B2 (de)
AT (1) ATE161174T1 (de)
AU (1) AU6421594A (de)
BE (1) BE1006990A5 (de)
CA (1) CA2161016A1 (de)
DE (1) DE69407404T2 (de)
DK (1) DK0695172T3 (de)
ES (1) ES2113095T3 (de)
GR (1) GR3026338T3 (de)
WO (1) WO1994023700A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4318577A1 (de) * 1993-06-04 1994-12-08 Merck Patent Gmbh Schmiermittelfreie, arzneimittelhaltige Tabletten
US5455046A (en) * 1993-09-09 1995-10-03 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5773025A (en) * 1993-09-09 1998-06-30 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems--amorphous drugs
CA2159419C (en) * 1994-10-17 2006-07-04 Pieter De Haan Solid pharmaceutical composition comprising an excipient capable of binding water
NZ270439A (en) * 1995-02-02 1996-04-26 Bernard Charles Sherman Solid slow release pharmaceutical composition: carrier is polyethylene glycol and hydrophilic gel-forming polymer
TWI225402B (en) * 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
ES2322405T3 (es) 1996-07-08 2009-06-19 Penwest Pharmaceuticals Co. Matriz de liberacion controlada para farmacos insolubles en dosis elevadas.
JP2002528042A (ja) * 1997-10-07 2002-08-27 フイズ テクノロジーズ リミテッド 改善された放出特性を有する投与形態
US6056977A (en) 1997-10-15 2000-05-02 Edward Mendell Co., Inc. Once-a-day controlled release sulfonylurea formulation
FR2775597B1 (fr) * 1998-03-04 2001-04-20 Gattefosse Ets Sa Pellet administrable par voie orale apte a ameliorer la biodisponibilite de la substance active, procede de fabrication
WO2000024380A1 (en) * 1998-10-27 2000-05-04 Fuisz Technologies Ltd. Microparticles containing peg and/or peg glyceryl esters
US7374779B2 (en) * 1999-02-26 2008-05-20 Lipocine, Inc. Pharmaceutical formulations and systems for improved absorption and multistage release of active agents
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US20030236236A1 (en) * 1999-06-30 2003-12-25 Feng-Jing Chen Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
AU5066101A (en) * 2000-04-13 2001-10-30 Synthon B.V. Modified release formulations containing a hypnotic agent
SE0200154D0 (sv) * 2002-01-21 2002-01-21 Galenica Ab New process
WO2003072085A1 (fr) * 2002-02-27 2003-09-04 Shionogi & Co., Ltd. Preparations solides contenant un medicament a peine soluble dans l'eau d'une meilleure absorbabilite
GB0205253D0 (en) * 2002-03-06 2002-04-17 Univ Gent Immediate release pharmaceutical granule compositions and a continuous process for making them
US20060003002A1 (en) * 2003-11-03 2006-01-05 Lipocine, Inc. Pharmaceutical compositions with synchronized solubilizer release
US20070190141A1 (en) * 2006-02-16 2007-08-16 Aaron Dely Extended release opiate composition
GB0612695D0 (en) * 2006-06-27 2006-08-09 Univ Gent Process for preparing a solid dosage form
EP2051696A2 (de) * 2006-08-18 2009-04-29 Morton Grove Pharmaceuticals, Inc. Stabile flüssige levetiracetam-zusammensetzungen und verfahren
CA2718416C (en) * 2008-03-13 2018-01-02 Mallinckrodt Inc. Multi-function, foot-activated controller for imaging system
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
US20110150986A1 (en) * 2009-12-18 2011-06-23 Kristin Arnold Quinine formulations, method of making, and metho of use thereof
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
WO2016033549A2 (en) 2014-08-28 2016-03-03 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
WO2016033556A1 (en) 2014-08-28 2016-03-03 Lipocine Inc. BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS
WO2018098501A1 (en) 2016-11-28 2018-05-31 Lipocine Inc. Oral testosterone undecanoate therapy
WO2020262536A1 (en) 2019-06-26 2020-12-30 Ricoh Company, Ltd. Instantly soluble particle and method for producing the same
KR20220024756A (ko) 2019-06-26 2022-03-03 가부시키가이샤 리코 의약 조성물

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3146167A (en) * 1961-10-05 1964-08-25 Smith Kline French Lab Method of preparing sustained release pellets and products thereof
GB1148802A (en) * 1965-06-18 1969-04-16 Eastman Kodak Co Microcrystalline cellulose granules containing useful oils
CH523017A (de) * 1969-11-21 1972-05-31 Agripat Sa Schädlingsbekämpfungsmittel
US3655864A (en) * 1970-09-21 1972-04-11 Smith Kline French Lab Glyceryl tristerate and higher fatty acid mixture for improving digestive absorption
GB1367608A (en) * 1973-03-09 1974-09-18 Biolog Concepts Inc Oral pharmaceutical dosage form
USRE33963E (en) * 1981-10-29 1992-06-16 Bayer Aktiengesellschaft Solid rapidly released medicament preparations containing dihydropyridines, and processes for their preparation
FR2581541B1 (fr) * 1985-05-09 1988-05-20 Rhone Poulenc Sante Nouvelles compositions pharmaceutiques permettant la liberation prolongee d'un principe actif et leur procede de preparation
LU86099A1 (fr) * 1985-09-30 1987-04-02 Pharlyse Formes galeniques a liberation prolongee du verapamil,leur fabrication et medicaments les contenant
SE8601624D0 (sv) * 1986-04-11 1986-04-11 Haessle Ab New pharmaceutical preparations
DD249186A1 (de) * 1986-05-26 1987-09-02 Univ Halle Wittenberg Herstellungsverfahren einer neuen glibenclamid-arzneiform mit hoher bioverfuegbarkeit
ES2040697T3 (es) * 1986-12-18 1993-11-01 Kurt H. Prof. Dr. Bauer Concentrado de nifedipina estabilizado frente a la influencia de la luz, y procedimiento para su preparacion.
AR240018A1 (es) * 1987-10-07 1990-01-31 Merrell Pharma Inc Procedimiento para preparar una composicion que comprende derivados de piperidinoalcanol.
HU203041B (en) * 1989-03-14 1991-05-28 Egyt Gyogyszervegyeszeti Gyar Process for producing pharmaceutical compositions of controlled releasing factor containing nifedipin
EP0418596A3 (en) 1989-09-21 1991-10-23 American Cyanamid Company Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form
US5169645A (en) * 1989-10-31 1992-12-08 Duquesne University Of The Holy Ghost Directly compressible granules having improved flow properties
SE9003296L (sv) * 1990-10-16 1992-04-17 Kabi Pharmacia Ab Foerfarande foer att formulera laekemedel
US5288505A (en) * 1991-06-26 1994-02-22 Galephar P.R., Inc., Ltd. Extended release form of diltiazem
JPH0597672A (ja) * 1991-10-08 1993-04-20 Terumo Corp アミド誘導体含有固形製剤およびその製造方法

Also Published As

Publication number Publication date
ES2113095T3 (es) 1998-04-16
DK0695172T3 (da) 1998-08-24
CA2161016A1 (en) 1994-10-27
GR3026338T3 (en) 1998-06-30
US6368634B1 (en) 2002-04-09
BE1006990A5 (nl) 1995-02-07
JP2960169B2 (ja) 1999-10-06
EP0695172B1 (de) 1997-12-17
ATE161174T1 (de) 1998-01-15
AU6421594A (en) 1994-11-08
JPH09500093A (ja) 1997-01-07
WO1994023700A1 (en) 1994-10-27
EP0695172A1 (de) 1996-02-07
DE69407404T2 (de) 1998-07-02

Similar Documents

Publication Publication Date Title
DE69407404T2 (de) Feste zubereitung mit hoher freisetzung, ihre herstellung und verwendung
DE69216642D1 (de) Verfahren zur herstellung von tabletten mit hoher festigkeit
MY129941A (en) Novel dihydro-isoquinoline derivatives
AU582920B2 (en) Continuous release pharmaceutical compositions
DE69006947D1 (de) Stabilisiertes FGF-Mittel und dessen Herstellung.
IL117532A0 (en) Production of compositions in the form of a solid solution of an active substance in a polymer matrix
DE122005000055I1 (de) Kristallines ceftiofur (freie S{ure)
DK74187D0 (da) Praeparat til langsom frigivelse samt fremgangsmaade til fremstilling deraf
ES2124373T3 (es) Procedimiento para la preparacion de derivados del acido n-acil-n,n',n'-etilendiamintriacetico.
DE69427908T2 (de) Eine gelpräparation aus vernetzter gelatine, die einen basischen wachstumsfaktor für fibroblasten enthält
ATE221773T1 (de) Formulierungen mit gesteuerter freisetzung
PL318789A1 (en) Sprayable film-forming system capable to release an active substance contained in them and intended to use them on plants
IS1620B (is) Aðferð til framleiðslu á lyfjablöndum sem innihalda nifedipine
DE69001573T2 (de) Zusammensetzungen zur herstellung von in dosisformen aktiven vitaminen d3 sowie verfahren zur herstellung stabiler, in dosisformen aktiver vitamine d3 unter deren verwendung.
DE69431162D1 (en) Fenbendazolformulierungen
AU8375891A (en) Antioxidant system based on a basic amino acid in combination with a tocopherol or derivative thereof and a nonthiolated polypeptide, and compositions containing the same
ATE147742T1 (de) 8-alpha-acylamino-ergoline, ihre herstellung und verwendung als arzneimittel
ATE115565T1 (de) 2-halogensubstituierte n-indolylethyl- sulfonsäureamide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln.
JPS53114629A (en) Data highway system
AU5269696A (en) Anellated beta-carbolines

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: UNIVERSITEIT GENT, GENT, BE

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee