ES2040697T3 - Concentrado de nifedipina estabilizado frente a la influencia de la luz, y procedimiento para su preparacion. - Google Patents
Concentrado de nifedipina estabilizado frente a la influencia de la luz, y procedimiento para su preparacion.Info
- Publication number
- ES2040697T3 ES2040697T3 ES198686117660T ES86117660T ES2040697T3 ES 2040697 T3 ES2040697 T3 ES 2040697T3 ES 198686117660 T ES198686117660 T ES 198686117660T ES 86117660 T ES86117660 T ES 86117660T ES 2040697 T3 ES2040697 T3 ES 2040697T3
- Authority
- ES
- Spain
- Prior art keywords
- nifedipine
- influence
- procedure
- preparation
- light
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
SE DESCRIUBE UN CONCENTRADO DE NIFEDIPINA ESTABILIZADO FRENTE A LA INFLUENCIA DE LA LUZ QUE SE CARACTERIZA PORQUE CONTIENE NIFEDIPINA, POLIETILENGLUCOL, 0,5 A 20% DE PESO DE VITAMINA B2, REFERIDO A LA NIFEDIPINA, AL MENOS EN TENSIDO Y DADO EL CASO LOS HABITUALES SOPORTES. SE DESCRIBE ADEMAS UN PROCEDIMIENTO PARA LA FABRICACION DEL CONCENTRADO DE NIFEDIPINA ASI COMO UN MEDICAMENTO QUE LO CONTIENE Y LA UTILIZACION PARA LA FABRICACION DE MEDICAMENTOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP86117660A EP0272336B1 (de) | 1986-12-18 | 1986-12-18 | Gegenüber Lichteinfluss stabilisiertes Nifedipin-Konzentrat und Verfahren zu seiner Herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2040697T3 true ES2040697T3 (es) | 1993-11-01 |
Family
ID=8195654
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES198686117660T Expired - Lifetime ES2040697T3 (es) | 1986-12-18 | 1986-12-18 | Concentrado de nifedipina estabilizado frente a la influencia de la luz, y procedimiento para su preparacion. |
Country Status (7)
Country | Link |
---|---|
US (1) | US4904699A (es) |
EP (1) | EP0272336B1 (es) |
JP (1) | JPS63165318A (es) |
AT (1) | ATE68704T1 (es) |
DE (1) | DE3682208D1 (es) |
ES (1) | ES2040697T3 (es) |
GR (1) | GR3003631T3 (es) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3738236A1 (de) * | 1987-11-11 | 1989-05-24 | Euro Celtique Sa | Beisskapsel |
HUT59592A (en) * | 1990-07-20 | 1992-06-29 | Egyt Gyogyszervegyeszeti Gyar | Process for the preparation of solid medical products |
US5145859A (en) * | 1991-03-20 | 1992-09-08 | Case Western Reserve University | Methods of treating interstitial cystitis and urethral syndrome |
US5229130A (en) * | 1991-12-20 | 1993-07-20 | Cygnus Therapeutics Systems | Vegetable oil-based skin permeation enhancer compositions, and associated methods and systems |
BE1006990A5 (nl) * | 1993-04-22 | 1995-02-07 | Univ Gent | Werkwijze en samenstelling om een aktief bestanddeel in een vaste toedieningsvorm te brengen. |
US6726930B1 (en) * | 1993-09-09 | 2004-04-27 | Penwest Pharmaceuticals Co. | Sustained release heterodisperse hydrogel systems for insoluble drugs |
US5773025A (en) * | 1993-09-09 | 1998-06-30 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems--amorphous drugs |
US5662933A (en) * | 1993-09-09 | 1997-09-02 | Edward Mendell Co., Inc. | Controlled release formulation (albuterol) |
US5455046A (en) * | 1993-09-09 | 1995-10-03 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems for insoluble drugs |
US5994348A (en) | 1995-06-07 | 1999-11-30 | Sanofi | Pharmaceutical compositions containing irbesartan |
AU695734B2 (en) | 1996-07-08 | 1998-08-20 | Penwest Pharmaceuticals Co. | Sustained release matrix for high-dose insoluble drugs |
US6056977A (en) | 1997-10-15 | 2000-05-02 | Edward Mendell Co., Inc. | Once-a-day controlled release sulfonylurea formulation |
US6168806B1 (en) | 1999-03-05 | 2001-01-02 | Fang-Yu Lee | Orally administrable nifedipine pellet and process for the preparation thereof |
DE19913692A1 (de) * | 1999-03-25 | 2000-09-28 | Basf Ag | Mechanisch stabile pharmazeutische Darreichungsformen, enthaltend flüssige oder halbfeste oberflächenaktive Substanzen |
WO2001022940A1 (en) * | 1999-09-30 | 2001-04-05 | Edward Mendell Co., Inc. | Sustained release matrix systems for highly soluble drugs |
US7364752B1 (en) | 1999-11-12 | 2008-04-29 | Abbott Laboratories | Solid dispersion pharamaceutical formulations |
JP5767429B2 (ja) * | 1999-11-12 | 2015-08-19 | アッヴィ・インコーポレイテッド | 固体分散剤中の結晶化阻害剤 |
DE10026698A1 (de) * | 2000-05-30 | 2001-12-06 | Basf Ag | Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung |
CA2519779A1 (en) * | 2003-03-26 | 2004-10-14 | Teva Pharmaceutical Industries Ltd. | A process for preparing a pharmaceutical active ingredient with high specific surface area |
US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
WO2008067164A2 (en) * | 2006-11-15 | 2008-06-05 | Abbott Laboratories | Solid pharmaceutical dosage formulations |
GB0703514D0 (en) * | 2007-02-23 | 2007-04-04 | Univ Ulster | Use of riboflavin |
JP6215238B2 (ja) * | 2012-02-16 | 2017-10-18 | テバ ファーマシューティカル インダストリーズ リミティド | N−エチル−n−フェニル−1,2−ジヒドロ−4,5−ジ−ヒドロキシ−1−メチル−2−オキソ−3−キノリンカルボキサミド、その製剤、および使用 |
CA2968861C (en) | 2017-05-30 | 2022-10-11 | University Of Saskatchewan | Topical nifedipine formulations and uses thereof |
JP7443663B2 (ja) * | 2018-11-07 | 2024-03-06 | ディーエスエム アイピー アセッツ ビー.ブイ. | 改善された流動性を示す、リボフラビンを含有する薬剤 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU432703A3 (es) * | 1971-08-24 | 1974-06-15 | Фридрих Боссерт, Вульф Фатер, Курт Бауер | |
GB1579818A (en) * | 1977-06-07 | 1980-11-26 | Yamanouchi Pharma Co Ltd | Nifedipine-containing solid preparation composition |
GB2111978B (en) * | 1981-10-19 | 1985-05-01 | Maruko Pharmaceutical Co | 1 4-dihydropyridine compounds |
DE3339236A1 (de) * | 1983-10-28 | 1985-05-09 | Bayer Ag | Arzneimittelzubereitung |
DE3438830A1 (de) * | 1984-10-23 | 1986-04-30 | Rentschler Arzneimittel | Nifedipin enthaltende darreichungsform und verfahren zu ihrer herstellung |
DE3532129A1 (de) * | 1985-09-10 | 1987-03-12 | Bayer Ag | Ss-carotin enthaltende gelatine |
-
1986
- 1986-12-18 ES ES198686117660T patent/ES2040697T3/es not_active Expired - Lifetime
- 1986-12-18 DE DE8686117660T patent/DE3682208D1/de not_active Expired - Lifetime
- 1986-12-18 EP EP86117660A patent/EP0272336B1/de not_active Expired - Lifetime
- 1986-12-18 AT AT86117660T patent/ATE68704T1/de not_active IP Right Cessation
-
1987
- 1987-12-07 US US07/129,767 patent/US4904699A/en not_active Expired - Fee Related
- 1987-12-15 JP JP62315404A patent/JPS63165318A/ja active Pending
-
1992
- 1992-01-23 GR GR910401306T patent/GR3003631T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0272336A1 (de) | 1988-06-29 |
GR3003631T3 (es) | 1993-03-16 |
JPS63165318A (ja) | 1988-07-08 |
DE3682208D1 (de) | 1991-11-28 |
ATE68704T1 (de) | 1991-11-15 |
US4904699A (en) | 1990-02-27 |
EP0272336B1 (de) | 1991-10-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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