ZA200206075B - Dual inhibitors of cholesterol ester and wax ester synthesis for sebaceous gland disorders. - Google Patents
Dual inhibitors of cholesterol ester and wax ester synthesis for sebaceous gland disorders. Download PDFInfo
- Publication number
- ZA200206075B ZA200206075B ZA200206075A ZA200206075A ZA200206075B ZA 200206075 B ZA200206075 B ZA 200206075B ZA 200206075 A ZA200206075 A ZA 200206075A ZA 200206075 A ZA200206075 A ZA 200206075A ZA 200206075 B ZA200206075 B ZA 200206075B
- Authority
- ZA
- South Africa
- Prior art keywords
- composition
- substance
- phenyl
- acetyl
- disorder
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| US17977800P | 2000-02-02 | 2000-02-02 |
Publications (1)
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|---|---|
| ZA200206075B true ZA200206075B (en) | 2003-10-30 |
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| ZA200206075A ZA200206075B (en) | 2000-02-02 | 2002-07-30 | Dual inhibitors of cholesterol ester and wax ester synthesis for sebaceous gland disorders. |
Country Status (34)
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| US (2) | US6730703B2 (xx) |
| EP (1) | EP1263421B1 (xx) |
| JP (1) | JP2003531113A (xx) |
| KR (1) | KR20020073574A (xx) |
| CN (1) | CN1398182A (xx) |
| AP (1) | AP2002002612A0 (xx) |
| AT (1) | ATE295724T1 (xx) |
| AU (1) | AU781563B2 (xx) |
| BG (1) | BG107042A (xx) |
| BR (1) | BR0107954A (xx) |
| CA (1) | CA2398219A1 (xx) |
| CR (1) | CR6712A (xx) |
| DE (1) | DE60110897T2 (xx) |
| DZ (1) | DZ3288A1 (xx) |
| EA (1) | EA004255B1 (xx) |
| EE (1) | EE200200429A (xx) |
| ES (1) | ES2239145T3 (xx) |
| GE (1) | GEP20043286B (xx) |
| HR (1) | HRP20020717A2 (xx) |
| HU (1) | HUP0301010A3 (xx) |
| IL (1) | IL150865A0 (xx) |
| IS (1) | IS6478A (xx) |
| MA (1) | MA26872A1 (xx) |
| MX (1) | MXPA02007309A (xx) |
| NO (1) | NO20023659L (xx) |
| NZ (1) | NZ520330A (xx) |
| OA (1) | OA12173A (xx) |
| PL (1) | PL357041A1 (xx) |
| PT (1) | PT1263421E (xx) |
| SK (1) | SK10972002A3 (xx) |
| UA (1) | UA75345C2 (xx) |
| WO (1) | WO2001056556A2 (xx) |
| YU (1) | YU57502A (xx) |
| ZA (1) | ZA200206075B (xx) |
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| EP1281399A3 (en) * | 2001-08-01 | 2004-02-11 | Warner-Lambert Company | Dual inhibitors of wax ester and cholesteryl ester synthesis for inhibiting sebum production |
| US20050031699A1 (en) | 2003-06-26 | 2005-02-10 | L'oreal | Porous particles loaded with cosmetically or pharmaceutically active compounds |
| ES2313065T3 (es) | 2003-10-09 | 2009-03-01 | Warner-Lambert Company Llc | Composiciones farmaceuticas que comprenden derivados de malonamida para disminuir la produccion de sebo. |
| AU2006217529C1 (en) | 2005-02-24 | 2013-03-07 | Medicis Pharmaceutical Corporation | Crystalline ACAT inhibitor |
| FR2904002A1 (fr) * | 2006-07-19 | 2008-01-25 | Galderma Res & Dev S N C Snc | Modulateurs de la lanosterol synthetase dans le traitement de l'acne ou de l'hyperseborrhee |
| FR2903999B1 (fr) * | 2006-07-19 | 2008-09-05 | Galderma Res & Dev S N C Snc | Modulateurs de sc4mol dans le traitement de l'acne ou de l'hyperseborrhee |
| FR2938342A1 (fr) * | 2008-11-13 | 2010-05-14 | Galderma Res & Dev | Ciblage de modulateurs de ces1 et/ou ces3 dans le traitement de l'acne, d'une dermatite seborrheique ou de l'hyperseborrhee |
| US20100226983A1 (en) | 2009-01-28 | 2010-09-09 | Nanobio Corporation | Compositions for treatment and prevention of acne, methods of making the compositions, and methods of use thereof |
| BR112020025208A2 (pt) * | 2018-06-21 | 2021-03-09 | Dermavant Sciences GmbH | Formulações tópicas de inibidores de dgat1 e seus métodos de uso |
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| US4545977A (en) * | 1985-01-11 | 1985-10-08 | G. D. Searle & Co. | Compositions and methods for treating severe acne with isotretinoin |
| US4751026A (en) | 1986-03-24 | 1988-06-14 | Warner-Lambert Company | Substituted anilides of oleic, linoleic, or linolenic acid as inhibitors of acyl-coa:cholesterol acyltransferase |
| US4722927A (en) | 1986-04-28 | 1988-02-02 | Warner-Lambert Company | Pyrimidine amides of oleic or linoleic acid, composition containing them and their use as inhibitors of acyl-CoA cholesterol acyltransferase |
| EP0252524A3 (en) | 1986-07-11 | 1989-04-19 | Warner-Lambert Company | Aryl- and aralkylamide- derivatives of omega- (substituted-phenyloxy)-alkanoic acids as inhibitors of acyl-coa: cholesterol acyltransferase and pharmaceuticals containing them |
| US4716175A (en) | 1987-02-24 | 1987-12-29 | Warner-Lambert Company | Saturated fatty acid amides as inhibitors of acyl-CoA:cholesterol acyltransferase |
| US5015644A (en) | 1987-06-02 | 1991-05-14 | Warner-Lambert Company | Antihyperlipidemic and antiatherosclerotic urea and carbamate compounds |
| IE61716B1 (en) | 1987-06-02 | 1994-11-30 | Warner Lambert Co | Antihyperlipidemic and antiatherosclerotic urea compounds |
| ATE61574T1 (de) | 1987-07-02 | 1991-03-15 | Warner Lambert Co | N-((2,6-disubstituierte)-phenyl>-harnstoff und - carbamat-inhibitoren der acyl-coenzym a:cholesterol-acyltransferase. |
| US5116848A (en) | 1988-03-30 | 1992-05-26 | Warner-Lambert Company | N-(((2,6-disubstituted)phenyl)-n-diarylalkyl)ureas as antihyperlipidemic and antiatherosclerotic agents |
| US4999373A (en) | 1988-03-30 | 1991-03-12 | Warner-Lambert Company | Antihyperlipidemic and antiatherosclerotic compounds and compositions |
| US4948806A (en) | 1988-03-30 | 1990-08-14 | Warner-Lambert Company | Antihyperlipidemic and antiatherosclerotic compounds and compositions |
| US5030653A (en) | 1988-03-30 | 1991-07-09 | Warner-Lambert Company | Antihyperlipidemic and antiatherosclerotic compounds and compositions |
| US4868210A (en) | 1988-03-30 | 1989-09-19 | Warner-Lambert Company | Antihyperlipidemic and antiatherosclerotic compounds and compositions |
| US5155127A (en) | 1989-02-09 | 1992-10-13 | Warner-Lambert Company | N-(substituted aryl)-n'-(substituted alkoxy)-ureas and thioureas as antihypercholesterolemic and antiatherosclerotic agents |
| US4923896A (en) | 1989-02-09 | 1990-05-08 | Warner-Lambert Company | N-(substituted aryl)-N'-(substituted alkoxy)-ureas and thioureas as antihypercholesterolemic and antiatherosclerotic agents |
| US4994465A (en) | 1989-02-17 | 1991-02-19 | Warner-Lambert Company | Antihyperlipidemic and antiatherosclerotic trisubstituted urea compounds |
| AU632809B2 (en) | 1989-05-25 | 1993-01-14 | Takeda Chemical Industries Ltd. | Benzocycloalkane benzopyran and benzothiopyran urea derivatives and production thereof |
| AU629376B2 (en) | 1989-08-04 | 1992-10-01 | Mitsubishi Chemical Corporation | 1-phenylalkyl-3-phenylurea derivatives |
| MX22406A (es) | 1989-09-15 | 1994-01-31 | Pfizer | Nuevos derivados de n-aril y n-heteroarilamidas y urea como inhibidores de acil coenzima a: acil transferasa del colesterol (acat). |
| TW205037B (xx) | 1989-10-06 | 1993-05-01 | Takeda Pharm Industry Co Ltd | |
| JPH05310678A (ja) | 1990-01-22 | 1993-11-22 | Mitsubishi Kasei Corp | １−フェニルアルキル−３−フェニル尿素誘導体 |
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| ATE175196T1 (de) | 1992-01-23 | 1999-01-15 | Pfizer | 4-phenyl-3-(heteroarylureido)-1,2-dihydro-2- oxochinolin derivate, als antihypercholesterolemische und antiatherosklerotische mittel |
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-
2001
- 2001-01-23 CA CA002398219A patent/CA2398219A1/en not_active Abandoned
- 2001-01-23 CN CN01804520A patent/CN1398182A/zh active Pending
- 2001-01-23 JP JP2001556248A patent/JP2003531113A/ja active Pending
- 2001-01-23 MX MXPA02007309A patent/MXPA02007309A/es active IP Right Grant
- 2001-01-23 DZ DZ013288A patent/DZ3288A1/fr active
- 2001-01-23 PT PT01948936T patent/PT1263421E/pt unknown
- 2001-01-23 IL IL15086501A patent/IL150865A0/xx unknown
- 2001-01-23 WO PCT/US2001/002190 patent/WO2001056556A2/en active IP Right Grant
- 2001-01-23 GE GEAP20016597A patent/GEP20043286B/en unknown
- 2001-01-23 EA EA200200764A patent/EA004255B1/ru not_active IP Right Cessation
- 2001-01-23 AP APAP/P/2002/002612A patent/AP2002002612A0/en unknown
- 2001-01-23 HU HU0301010A patent/HUP0301010A3/hu unknown
- 2001-01-23 NZ NZ520330A patent/NZ520330A/en unknown
- 2001-01-23 YU YU57502A patent/YU57502A/sh unknown
- 2001-01-23 UA UA2002076160A patent/UA75345C2/uk unknown
- 2001-01-23 PL PL01357041A patent/PL357041A1/xx not_active Application Discontinuation
- 2001-01-23 EE EEP200200429A patent/EE200200429A/xx unknown
- 2001-01-23 SK SK1097-2002A patent/SK10972002A3/sk not_active Application Discontinuation
- 2001-01-23 EP EP01948936A patent/EP1263421B1/en not_active Expired - Lifetime
- 2001-01-23 DE DE60110897T patent/DE60110897T2/de not_active Expired - Fee Related
- 2001-01-23 OA OA1200200234A patent/OA12173A/en unknown
- 2001-01-23 US US10/182,847 patent/US6730703B2/en not_active Expired - Fee Related
- 2001-01-23 AU AU29718/01A patent/AU781563B2/en not_active Ceased
- 2001-01-23 BR BR0107954-9A patent/BR0107954A/pt not_active Application Discontinuation
- 2001-01-23 ES ES01948936T patent/ES2239145T3/es not_active Expired - Lifetime
- 2001-01-23 AT AT01948936T patent/ATE295724T1/de not_active IP Right Cessation
- 2001-01-23 KR KR1020027009943A patent/KR20020073574A/ko not_active Application Discontinuation
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2002
- 2002-07-19 IS IS6478A patent/IS6478A/is unknown
- 2002-07-24 CR CR6712A patent/CR6712A/es not_active Application Discontinuation
- 2002-07-30 ZA ZA200206075A patent/ZA200206075B/en unknown
- 2002-08-01 MA MA26756A patent/MA26872A1/fr unknown
- 2002-08-01 NO NO20023659A patent/NO20023659L/no not_active Application Discontinuation
- 2002-08-29 BG BG107042A patent/BG107042A/bg unknown
- 2002-08-30 HR HR20020717A patent/HRP20020717A2/hr not_active Application Discontinuation
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2004
- 2004-02-06 US US10/773,354 patent/US20040161393A1/en not_active Abandoned
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