KR900017590A - 좌창(Acne)치료방법 및 그 약제 조성물 - Google Patents

좌창(Acne)치료방법 및 그 약제 조성물 Download PDF

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KR900017590A
KR900017590A KR1019900006234A KR900006234A KR900017590A KR 900017590 A KR900017590 A KR 900017590A KR 1019900006234 A KR1019900006234 A KR 1019900006234A KR 900006234 A KR900006234 A KR 900006234A KR 900017590 A KR900017590 A KR 900017590A
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ketoconazole
skin
pharmaceutical composition
acne
keratinous
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KR1019900006234A
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KR0161526B1 (ko
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프랑스 마리아 잔 카우웬 버그 제타르드
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구스타프 반 리이프
쟈안센 파아마 슈우리카 엔.브이
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nanotechnology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • General Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Rheumatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

내용 없음

Description

좌창(Acne)치료방법 및 그 약제 조성물
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (14)

  1. 피부수용성 담체와 0.1 내지 10중량%의 케토코나졸로 이루어진 좌창, 각화성 피부병 및 피부광침해 증상을 치료하는 약제 조성물.
  2. 제1항에 있어서, 0.005 내지 0.5%의 레티노이드를 함유하는 약제조성물.
  3. 제2항에 있어서, 1내지 40%의 시클로덱스트린 또는 그 에테르 유도체를 함유하는 약제 조성물.
  4. 제3항에 있어서, 0.5내지 5%의 케토코나졸과 5내지 25%의 시클로덱스트린 또는 그 에테르 유도체를 함유하는 약제 조성물.
  5. 제4항에 있어서, 1내지 2%의 케토코나졸, 0.01내지 0.1%의 레티노이드 및 10 내지 20%의 시클로덱스트린 또는 그 에테르 유도체를 함유하는 약제 조성물.
  6. 유효성분과 담체를 균일하게 혼합하여, 제1항 내지 제5항의 약제 조성물을 제조하는 방법.
  7. 좌창, 각화성 피부병(hyperkeratonic dermatose) 및 피부광 침해증상에 국부치료제로서 사용하는 케토코나졸의 용도.
  8. 제7항에 있어, 케토코나졸을 제1항 내지 제5항의 조성물로 제제하는 케토코나졸의 용도.
  9. 좌창, 각화성 피부병 및 피부광 침해증상에 국부, 치료제 제조에 사용하는 케토코나졸의 용도.
  10. 제9항에 있어서, 치료제가 제1항 내지 제5항의 조성물인 케토코나졸의 용도.
  11. 좌창, 각화성 피부병 및 피부광 침해증상에 감염된 피부환부에 케토코나졸 효과량을 투여하여 국부 치료하는 방법.
  12. 제11항에 있어, 케토코나졸을 제1항 내지 제5항의 조성물로 제제한 방법.
  13. 좌창, 각화성 피부병 및 피부광 침해증상에 각각 동시, 분리 또는 시차연용하는 배합용 제제인 케토코나졸과 레티노이드로 이루어진 제품.
  14. ※ 참고사항 : 최초출원내용에 의하여 공개하는 것임.
KR1019900006234A 1989-05-03 1990-05-03 심상성 좌창의 국소치료용 조성물 KR0161526B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898910069A GB8910069D0 (en) 1989-05-03 1989-05-03 Method of topically treating acne vulgaris
GB89100697 1989-05-03

Publications (2)

Publication Number Publication Date
KR900017590A true KR900017590A (ko) 1990-12-19
KR0161526B1 KR0161526B1 (ko) 1998-12-01

Family

ID=10656092

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900006234A KR0161526B1 (ko) 1989-05-03 1990-05-03 심상성 좌창의 국소치료용 조성물

Country Status (16)

Country Link
EP (1) EP0396184B1 (ko)
JP (1) JP2833711B2 (ko)
KR (1) KR0161526B1 (ko)
AT (1) ATE145136T1 (ko)
AU (1) AU626672B2 (ko)
CA (1) CA2015838C (ko)
DE (1) DE69029100T2 (ko)
DK (1) DK0396184T3 (ko)
ES (1) ES2096577T3 (ko)
GB (1) GB8910069D0 (ko)
GR (1) GR3022519T3 (ko)
IE (1) IE74192B1 (ko)
IL (1) IL94267A (ko)
PT (1) PT93935B (ko)
SG (1) SG47035A1 (ko)
ZA (1) ZA903339B (ko)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5559149A (en) 1990-01-29 1996-09-24 Johnson & Johnson Consumer Products, Inc. Skin care compositions containing retinoids
US5583136A (en) * 1990-01-29 1996-12-10 Johnson & Johnson Consumer Products, Inc. Retinoid containing skin care compositions containing imidazoles
GB9014221D0 (en) * 1990-06-26 1990-08-15 Janssen Pharmaceutica Nv Method of treating alopecia
LU87843A1 (fr) * 1990-11-15 1992-08-25 Cird Galderma Gel aqueux a base d'acide retinoique et d'hydroxypropyl-beta-cyclodextrine et son utilisation en medecine humaine et en cosmetique
GR1002207B (en) * 1992-08-06 1996-03-27 Johnson & Johnson Consumer Skin care compositions containing imidazoles.
AU5955094A (en) * 1992-12-22 1994-07-19 Sepracor, Inc. Methods and compositions of (-) ketoconazole for treating fungal yeast and dermatophyte infections
ES2064288B1 (es) * 1993-07-06 1995-08-01 Ornosa Enrique Viayna Composicion para el tratamiento de afecciones cutaneas, su preparacion y su uso.
TW460296B (en) * 1994-09-01 2001-10-21 Janssen Pharmaceutica Nv Topical ketoconazole emulsion compositions without sodium sulfite
US5556871A (en) * 1995-04-24 1996-09-17 President & Fellows Of Harvard College Method for treating epithelial precancerous lesions with topical inidazoles
GB2307176A (en) * 1995-11-15 1997-05-21 Todd Selwyn Everest Anti-inflammatory clathrating agents for topical use
US5716627A (en) * 1996-04-25 1998-02-10 Elizabeth Arden Co., Division Of Conopco, Inc. Skin care compositions containing fatty acid amides, azoles, and retinol or retinyl ester
US6150403A (en) * 1997-10-14 2000-11-21 The Procter & Gamble Company Topical compositions for regulating the oily/shiny appearance of skin
KR100247558B1 (ko) * 1997-11-24 2000-05-01 김충섭 사이클로덱스트린을 이용한 이온토포레시스 개선방법
US6683100B2 (en) 1999-01-19 2004-01-27 Novartis Ag Organic compounds
US6194181B1 (en) 1998-02-19 2001-02-27 Novartis Ag Fermentative preparation process for and crystal forms of cytostatics
DE19943678A1 (de) * 1999-09-13 2001-03-15 Beiersdorf Ag Wirkstoffkombinationen aus oberflächenaktiven Citronensäureestern und Einschlußverbindungen von Cyclodextrinen und Retinoiden sowie kosmetische und dermatologische Zubereitungen mit einem Gehalt an solchen Gemischen
GB2365770B (en) * 2000-08-18 2002-07-31 Diomed Dev Ltd Antifungal ketoconazole composition for topical use
DE10131796A1 (de) * 2001-06-30 2003-01-16 Beiersdorf Ag Verwendung von Cardiolipin in kosmetischen oder dermatologischen Zubereitungen
DE10151245A1 (de) * 2001-10-17 2003-05-15 Beiersdorf Ag Kosmetische und/oder dermatologische Wirkstoffkombination
KR100432449B1 (ko) * 2001-11-30 2004-05-22 우원홍 케토코나졸 함유 피부 미백용 외용제 조성물
FR2835434B1 (fr) * 2002-02-01 2006-03-03 Lvmh Rech Utilisation cosmetique ou dermatologique de la vitamine a ou de ses esters, en association avec une beta-cyclodextrine partiellement methylee
US20090117203A1 (en) * 2006-03-23 2009-05-07 Tmrc Co., Ltd. Kit for cancer treatment and pharmaceutical composition for cancer treatment
WO2013107809A1 (en) * 2012-01-19 2013-07-25 Merz Pharma Gmbh & Co. Kgaa Use of azole antifungals for the treatment of actinic keratosis
CN108066342A (zh) * 2016-11-17 2018-05-25 江苏灵豹药业股份有限公司 一种复方酮康唑乳膏剂及其制备方法
CN115671285B (zh) * 2022-08-24 2024-01-05 上海市皮肤病医院 一种抗真菌溶液及其制备方法和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4144346A (en) * 1977-01-31 1979-03-13 Janssen Pharmaceutica N.V. Novel 1-(1,3-dioxolan-2-ylmethyl)-1H-imidazoles
GB2068228B (en) * 1980-01-24 1984-02-29 Janssen Pharmaceutica Nv Anti-microbial compositions for the topical treatment of acne vulgaris
US4371673A (en) * 1980-07-21 1983-02-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Water soluble forms of retinoids
GB2097783B (en) * 1981-04-23 1984-12-12 Dermal Lab Ltd Imidazoles
US4569935A (en) * 1983-03-17 1986-02-11 University Of Tennessee Research Corp. Topical treatment of psoriasis with imidazole antibiotics
DE3346123A1 (de) * 1983-12-21 1985-06-27 Janssen Pharmaceutica, N.V., Beerse Pharmazeutische praeparate von in wasser schwerloeslichen oder instabilen arzneistoffen und verfahren zu ihrer herstellung
EP0270316A3 (en) * 1986-12-04 1989-12-06 Pfizer Inc. Topical compositions comprising 1-substituted imidazoles and nsaids for treatment of acne
US4814333A (en) * 1987-07-28 1989-03-21 The Trustees Of Dartmouth College Method for treatment of hypercortisolemic, depressed patients

Also Published As

Publication number Publication date
JPH02295927A (ja) 1990-12-06
AU5471190A (en) 1990-11-15
CA2015838A1 (en) 1990-11-03
CA2015838C (en) 2002-08-27
AU626672B2 (en) 1992-08-06
IE74192B1 (en) 1997-07-16
IE901607L (en) 1990-11-03
KR0161526B1 (ko) 1998-12-01
GR3022519T3 (en) 1997-05-31
EP0396184A2 (en) 1990-11-07
PT93935A (pt) 1991-02-08
EP0396184B1 (en) 1996-11-13
GB8910069D0 (en) 1989-06-21
DK0396184T3 (da) 1996-12-30
IL94267A (en) 1994-11-11
ES2096577T3 (es) 1997-03-16
JP2833711B2 (ja) 1998-12-09
ATE145136T1 (de) 1996-11-15
SG47035A1 (en) 1998-03-20
PT93935B (pt) 1996-11-29
EP0396184A3 (en) 1992-05-20
ZA903339B (en) 1992-01-29
IL94267A0 (en) 1991-03-10
DE69029100D1 (de) 1996-12-19
DE69029100T2 (de) 1997-04-03

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