KR960010002A - L-카르니틴염과 이를 함유한 피부질환 치료용 화장품 조성물 및 약제 조성물 - Google Patents
L-카르니틴염과 이를 함유한 피부질환 치료용 화장품 조성물 및 약제 조성물 Download PDFInfo
- Publication number
- KR960010002A KR960010002A KR1019950019891A KR19950019891A KR960010002A KR 960010002 A KR960010002 A KR 960010002A KR 1019950019891 A KR1019950019891 A KR 1019950019891A KR 19950019891 A KR19950019891 A KR 19950019891A KR 960010002 A KR960010002 A KR 960010002A
- Authority
- KR
- South Korea
- Prior art keywords
- pharmaceutical composition
- carnitine
- structural formula
- composition according
- represented
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract 13
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical class C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 title claims abstract 7
- 208000017520 skin disease Diseases 0.000 title claims abstract 6
- 239000002537 cosmetic Substances 0.000 title claims abstract 4
- 239000000203 mixture Substances 0.000 title claims abstract 3
- 239000004480 active ingredient Substances 0.000 claims abstract 3
- 238000011200 topical administration Methods 0.000 claims abstract 2
- 229940067597 azelate Drugs 0.000 claims 4
- BDJRBEYXGGNYIS-UHFFFAOYSA-N nonanedioic acid Chemical compound OC(=O)CCCCCCCC(O)=O BDJRBEYXGGNYIS-UHFFFAOYSA-N 0.000 claims 4
- 206010020649 Hyperkeratosis Diseases 0.000 claims 2
- 102000011782 Keratins Human genes 0.000 claims 2
- 108010076876 Keratins Proteins 0.000 claims 2
- 208000001126 Keratosis Diseases 0.000 claims 2
- 230000007812 deficiency Effects 0.000 claims 2
- 208000002874 Acne Vulgaris Diseases 0.000 claims 1
- 208000001840 Dandruff Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 206010000496 acne Diseases 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- 239000006210 lotion Substances 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/362—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
Abstract
본 발명은 다음 구조식(Ⅰ)로 표시되는 신규 L-카르니틴염과 이를 함유한 피부질환 치료용 화장품 조성물 및 약제조성물에 관한 것으로서, 더욱 상세하게는 피부질환 치료를 위한 국소투여에 적합한 화장품 및 약제조성물의 유효성분으로서 신규 L-카르니틴염의 용도에 관한 것이다.
@ (Ⅰ)
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (8)
- 다음 구조식(Ⅰ)로 표시되는 L-카르니틴산 아젤레이트@ (Ⅰ)
- 다음 구조식(Ⅰ)로 표시되는 L-카르니틴산 아젤레이트를 유효성분으로 하고 약제학적으로 수용가능한 부형제로 이루어진 것을 특징으로 하는 피부질환 치료를 위한 국소투여에 적합한 약제조성물@ (Ⅰ)
- 제2항에 있어서, 상기 약제조성물은 어린선 및 건선의 치료에 사용되는 것을 특징으로 하는 약제조성물
- 제2항에 있어서, 상기 약제조성물은 각화결손에 의한 피부병 치료에 사용되는 것을 특징으로 하는 약제조성물
- 제4항에 있어서, 상기 각화결손에 의한 피부병으로는 비듬, 여드름, 손바닥각화증 또는 발바닥 각화증인 것을 특징으로 하는 약제조성물
- 제2항에 있어서, 상기 약제조성물은 용액, 로션, 연고 또는 크림 형태임을 특징으로 하는 약제조성물
- 제6항에 있어서, 상기 약제조성물은 상기 구조식(Ⅰ)로 표시되는 L-카르니틴산 아젤레이트를 0.01∼20중량% 함유하는 것을 특징으로 하는 약제조성물
- 다음 구조식(Ⅰ)로 표시되는 L-카르니틴산 아젤레이트를 유효성분으로 하고 화장품 제제학적으로 수용가능한 부형제로 이루어진 것을 특징으로 하는 화장품 조성물@ (Ⅰ)※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITRM94A000570 | 1994-09-08 | ||
ITRM940570A IT1274156B (it) | 1994-09-08 | 1994-09-08 | "sale della l-carnitina e composizioni farmaceutiche che lo contengonoper il trattamento di affezioni cutanee" |
Publications (2)
Publication Number | Publication Date |
---|---|
KR960010002A true KR960010002A (ko) | 1996-04-20 |
KR100366200B1 KR100366200B1 (ko) | 2003-03-03 |
Family
ID=11402717
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019950019891A KR100366200B1 (ko) | 1994-09-08 | 1995-07-07 | L-카르니틴염과이를함유한피부질환치료용화장품조성물및약제조성물 |
Country Status (14)
Country | Link |
---|---|
US (1) | US5637305A (ko) |
EP (1) | EP0700898B1 (ko) |
JP (1) | JP3831431B2 (ko) |
KR (1) | KR100366200B1 (ko) |
AT (1) | ATE160561T1 (ko) |
CA (1) | CA2157836C (ko) |
DE (1) | DE69501105T2 (ko) |
DK (1) | DK0700898T3 (ko) |
ES (1) | ES2111355T3 (ko) |
GR (1) | GR3026086T3 (ko) |
HK (1) | HK1004917A1 (ko) |
IT (1) | IT1274156B (ko) |
PH (1) | PH31607A (ko) |
ZA (1) | ZA957507B (ko) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1274156B (it) * | 1994-09-08 | 1997-07-15 | Avantgarde Spa | "sale della l-carnitina e composizioni farmaceutiche che lo contengonoper il trattamento di affezioni cutanee" |
IT1276253B1 (it) | 1995-12-15 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica contenente l-carnitina o alcanoil l-carnitine per la prevenzione ed il trattamento di stati morbosi |
IT1291113B1 (it) * | 1997-03-20 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Composizione nutritiva terapeutica per soggetti affetti da diabete mellito |
US6090848A (en) * | 1997-12-01 | 2000-07-18 | Sigma-Tau Healthscience S.P.A. | Compositions and methods for increasing the concentration and/or motility of spermatozoa in humans |
US5863940A (en) | 1997-12-01 | 1999-01-26 | Sigma-Tau Healthscience S.P.A. | Medicament and therapeutical method for treating idiopathic asthenozoospermia |
PT951909E (pt) | 1998-03-19 | 2004-04-30 | Sigma Tau Ind Farmaceuti | Composicao combinada que contem uma l-carnitina ou uma alcanoil-l-carnitina um glicosaminoglicano e/ou um seu constituinte |
US6475965B2 (en) * | 1999-12-28 | 2002-11-05 | Colgate-Palmolive Company | Skin moisturizing composition comprising a choline salt |
US6265364B1 (en) * | 1999-12-28 | 2001-07-24 | Colgate-Palmolive Company | Solid cleansing composition comprising a choline salt |
US6372791B1 (en) | 2000-06-29 | 2002-04-16 | Johnson & Johnson Consumer Companies, Inc. | Method of promoting skin cell metabolism |
US6649176B1 (en) | 2000-06-29 | 2003-11-18 | Johnson & Johnson Consumer Companies, Inc. | Compositions containing mineral water |
US6432424B1 (en) | 2000-06-29 | 2002-08-13 | Johnson & Johnson Consumer Companies, Inc. | Cosmetic compositions containing creatine, carnitine, and/or pyruvic acid |
US6630175B1 (en) | 2000-06-29 | 2003-10-07 | Johnson & Johnson Consumer Companies, Inc. | Method of reducing eye irritation |
WO2006074379A2 (en) * | 2005-01-07 | 2006-07-13 | Azaya Therapeutics, Inc. | Methods and compositions involving esters of azelaic acid and other dicarboxylic acids |
EA017935B1 (ru) | 2006-05-19 | 2013-04-30 | Мэри Кэй Инк. | Композиция для ухода за кожей и ее применение |
JP5951277B2 (ja) * | 2012-02-17 | 2016-07-13 | ロート製薬株式会社 | アゼライン酸を含有する外用組成物 |
KR102158895B1 (ko) | 2013-03-12 | 2020-09-22 | 마리 케이 인코포레이티드 | 보존 시스템 |
FR3090347B1 (fr) * | 2018-12-20 | 2020-12-18 | Oreal | Procédé de traitement des fibres kératiniques mettant en œuvre une composition comprenant un sel de carnitine ou de dérivé de carnitine comprenant un anion d’acide dicarboxylique aliphatique |
CN112250588B (zh) * | 2020-11-06 | 2023-03-31 | 哈尔滨工业大学(深圳) | 一种左旋肉碱离子液体及其制备方法、应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1156840B (it) * | 1978-06-27 | 1987-02-04 | Sigma Tau Ind Farmaceuti | Acil derivati della carnitina |
FR2529545B1 (fr) * | 1982-07-02 | 1985-05-31 | Sanofi Sa | Nouveaux sels de carnitine ainsi que leur procede de preparation |
JP2529545Y2 (ja) * | 1991-05-09 | 1997-03-19 | シャープ株式会社 | 電子機器の組付け装置 |
IT1254135B (it) * | 1992-01-16 | 1995-09-08 | Sigma Tau Ind Farmaceuti | Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antibatterica. |
IT1263013B (it) * | 1992-10-20 | 1996-07-23 | Avantgarde Spa | Esteri della l-carnitina e di alcanoil l-carnitine con l'acido glicolico o suoi esteri e composizioni farmaceutiche contenenti tali per il trattamento di affezioni cutanee. |
IT1274156B (it) * | 1994-09-08 | 1997-07-15 | Avantgarde Spa | "sale della l-carnitina e composizioni farmaceutiche che lo contengonoper il trattamento di affezioni cutanee" |
-
1994
- 1994-09-08 IT ITRM940570A patent/IT1274156B/it active IP Right Grant
-
1995
- 1995-06-07 US US08/482,544 patent/US5637305A/en not_active Expired - Lifetime
- 1995-06-12 DK DK95109026T patent/DK0700898T3/da active
- 1995-06-12 AT AT95109026T patent/ATE160561T1/de active
- 1995-06-12 EP EP95109026A patent/EP0700898B1/en not_active Expired - Lifetime
- 1995-06-12 ES ES95109026T patent/ES2111355T3/es not_active Expired - Lifetime
- 1995-06-12 DE DE69501105T patent/DE69501105T2/de not_active Expired - Lifetime
- 1995-06-13 PH PH50703A patent/PH31607A/en unknown
- 1995-07-07 KR KR1019950019891A patent/KR100366200B1/ko not_active IP Right Cessation
- 1995-09-07 ZA ZA957507A patent/ZA957507B/xx unknown
- 1995-09-08 JP JP23106695A patent/JP3831431B2/ja not_active Expired - Fee Related
- 1995-09-08 CA CA002157836A patent/CA2157836C/en not_active Expired - Fee Related
-
1998
- 1998-02-09 GR GR970401982T patent/GR3026086T3/el unknown
- 1998-05-09 HK HK98104023A patent/HK1004917A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IT1274156B (it) | 1997-07-15 |
JPH0892180A (ja) | 1996-04-09 |
ITRM940570A1 (it) | 1996-03-08 |
US5637305A (en) | 1997-06-10 |
KR100366200B1 (ko) | 2003-03-03 |
DE69501105D1 (de) | 1998-01-08 |
PH31607A (en) | 1998-11-03 |
HK1004917A1 (en) | 1998-12-11 |
CA2157836A1 (en) | 1996-03-09 |
CA2157836C (en) | 2006-08-22 |
DK0700898T3 (da) | 1998-08-10 |
ES2111355T3 (es) | 1998-03-01 |
JP3831431B2 (ja) | 2006-10-11 |
GR3026086T3 (en) | 1998-05-29 |
ITRM940570A0 (it) | 1994-09-08 |
DE69501105T2 (de) | 1998-04-16 |
EP0700898A1 (en) | 1996-03-13 |
ATE160561T1 (de) | 1997-12-15 |
ZA957507B (en) | 1996-04-18 |
EP0700898B1 (en) | 1997-11-26 |
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