KR960010003A - L-카르니틴염과 이를 함유한 피부질환 치료용 화장품 조성물 및 약제 조성물 - Google Patents
L-카르니틴염과 이를 함유한 피부질환 치료용 화장품 조성물 및 약제 조성물 Download PDFInfo
- Publication number
- KR960010003A KR960010003A KR1019950019892A KR19950019892A KR960010003A KR 960010003 A KR960010003 A KR 960010003A KR 1019950019892 A KR1019950019892 A KR 1019950019892A KR 19950019892 A KR19950019892 A KR 19950019892A KR 960010003 A KR960010003 A KR 960010003A
- Authority
- KR
- South Korea
- Prior art keywords
- pharmaceutical composition
- structural formula
- composition according
- represented
- skin disease
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract 13
- 208000017520 skin disease Diseases 0.000 title claims abstract 6
- 239000002537 cosmetic Substances 0.000 title claims abstract 4
- 239000000203 mixture Substances 0.000 title claims abstract 3
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical class C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 title abstract 3
- 239000004480 active ingredient Substances 0.000 claims abstract 3
- 238000011200 topical administration Methods 0.000 claims abstract 2
- MUXKDGQFSLPPKJ-ZCFIWIBFSA-N (3r)-3-(2,2,2-trichloroacetyl)oxy-4-(trimethylazaniumyl)butanoate Chemical compound C[N+](C)(C)C[C@@H](CC([O-])=O)OC(=O)C(Cl)(Cl)Cl MUXKDGQFSLPPKJ-ZCFIWIBFSA-N 0.000 claims 4
- 206010020649 Hyperkeratosis Diseases 0.000 claims 2
- 102000011782 Keratins Human genes 0.000 claims 2
- 108010076876 Keratins Proteins 0.000 claims 2
- 208000001126 Keratosis Diseases 0.000 claims 2
- 230000007812 deficiency Effects 0.000 claims 2
- 208000002874 Acne Vulgaris Diseases 0.000 claims 1
- 208000001840 Dandruff Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 206010000496 acne Diseases 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- 239000006210 lotion Substances 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Birds (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Abstract
본 발명은 다음 구조식(Ⅰ)로 표시되는 신규 L-카르니틴염과 이를 함유한 피부질환 치료용 화장품 조성물 및 약제조성물에 관한 것으로서, 더욱 상세하게는 피부질환 치료를 위한 국소투여에 적합한 화장품 및 약제조성물의 유효성분으로 신규 L-카르니틴염의 용도에 관한 것이다.
@ (Ⅰ)
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (8)
- 다음 구조식(Ⅰ)로 표시되는 L-카르니틴 트리클로로아세테이트@ (Ⅰ)
- 다음 구조식(Ⅰ)로 표시되는 L-카르니틴 트리클로로아세테이트를 유효성분으로 하고 약제학적으로 수용가능한 부형제로 이루어진 것을 특징으로 하는 피부질환 치료를 위한 국소투여에 적합한 약제조성물@ (Ⅰ)
- 제2항에 있어서, 상기 약제조성물은 어린선 및 건선의 치료에 사용되는 것을 특징으로 하는 약제조성물
- 제2항에 있어서, 상기 약제조성물은 각화결손에 의한 피부병 치료에 사용되는 것을 특징으로 하는 약제조성물
- 제4항에 있어서, 상기 각화결손에 의한 피부병으로는 비듬, 여드름, 손바닥각화증 또는 발바닥 각화증인 것을 특징으로 하는 약제조성물
- 제2항에 있어서, 상기 약제조성물은 용액, 로션, 연고 또는 크림 형태임을 특징으로 하는 약제조성물
- 제6항에 있어서, 상기 약제조성물은 상기 구조식(Ⅰ)로 표시되는 L-카르니틴트리클로로아세테이트를 0.01∼20중량% 함유하는 것을 특징으로 하는 약제조성물
- 다음 구조식(Ⅰ)로 표시되는 L-카르니틴 트리클로로아세테이트를 유효성분으로 하고 화장품 제제학적으로 수용가능한 부형제로 이루어진 것을 특징으로 하는 화장품 조성물@ (Ⅰ)※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITRM94A000571 | 1994-09-08 | ||
ITRM940571A IT1274157B (it) | 1994-09-08 | 1994-09-08 | "sale della l-carnitina e composizioni farmaceutiche che lo contengonoper il trattamento di affezioni cutanee" |
Publications (1)
Publication Number | Publication Date |
---|---|
KR960010003A true KR960010003A (ko) | 1996-04-20 |
Family
ID=11402718
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019950019892A KR960010003A (ko) | 1994-09-08 | 1995-07-07 | L-카르니틴염과 이를 함유한 피부질환 치료용 화장품 조성물 및 약제 조성물 |
Country Status (12)
Country | Link |
---|---|
US (1) | US5614556A (ko) |
EP (1) | EP0700897B1 (ko) |
JP (1) | JPH0892181A (ko) |
KR (1) | KR960010003A (ko) |
AT (1) | ATE168988T1 (ko) |
CA (1) | CA2157837A1 (ko) |
DE (1) | DE69503724T2 (ko) |
DK (1) | DK0700897T3 (ko) |
ES (1) | ES2120667T3 (ko) |
IT (1) | IT1274157B (ko) |
PH (1) | PH31608A (ko) |
ZA (1) | ZA957506B (ko) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1276253B1 (it) | 1995-12-15 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica contenente l-carnitina o alcanoil l-carnitine per la prevenzione ed il trattamento di stati morbosi |
IT1291113B1 (it) * | 1997-03-20 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Composizione nutritiva terapeutica per soggetti affetti da diabete mellito |
US6090848A (en) * | 1997-12-01 | 2000-07-18 | Sigma-Tau Healthscience S.P.A. | Compositions and methods for increasing the concentration and/or motility of spermatozoa in humans |
US5863940A (en) | 1997-12-01 | 1999-01-26 | Sigma-Tau Healthscience S.P.A. | Medicament and therapeutical method for treating idiopathic asthenozoospermia |
SI0951909T2 (sl) | 1998-03-19 | 2010-11-30 | Sigma Tau Ind Farmaceuti | Kombinirana zmes ki vsebuje L karnitin ali alkanoil L karnitin glikozaminoglikan in ali njegov sestavni del |
US6149924A (en) * | 1998-07-20 | 2000-11-21 | Biomed Research & Technologies, Inc. | Composition for enhancing lipid production, barrier function, hydrogen peroxide neutralization, and moisturization of the skin |
US6242491B1 (en) * | 1999-06-25 | 2001-06-05 | Rima Kaddurah-Daouk | Use of creatine or creatine compounds for skin preservation |
DE10129502A1 (de) * | 2001-06-19 | 2003-01-09 | Beiersdorf Ag | Verwendung von Carnitin und/oder einem oder mehreren Acyl-Carnitinen zur Herstellung von kosmetischen oder dermatologischen Zubereitungen zur Steigerung der Ceramidbiosynthese |
ITUD20050211A1 (it) | 2005-12-13 | 2007-06-14 | Rossana Castellana | Prodotto per il trattamento della pelle relativo procedimento di preparazione |
US20110160143A1 (en) * | 2009-12-28 | 2011-06-30 | Perricone Nicholas V | Topical Acyl Glutathione Psoriasis Compositions |
US9259343B2 (en) | 2012-07-06 | 2016-02-16 | Newman Technologies LLC | Device for mitigating plantar fasciitis |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2529545B1 (fr) * | 1982-07-02 | 1985-05-31 | Sanofi Sa | Nouveaux sels de carnitine ainsi que leur procede de preparation |
US4874361A (en) * | 1986-12-29 | 1989-10-17 | Obagi Zein E | Method for healing damaged skin |
IT1254135B (it) * | 1992-01-16 | 1995-09-08 | Sigma Tau Ind Farmaceuti | Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antibatterica. |
US5741816A (en) * | 1994-06-20 | 1998-04-21 | Tanabe Seiyaku Co., Ltd. | Hair-growth agent |
-
1994
- 1994-09-08 IT ITRM940571A patent/IT1274157B/it active IP Right Grant
-
1995
- 1995-06-07 US US08/473,211 patent/US5614556A/en not_active Expired - Fee Related
- 1995-06-12 AT AT95109025T patent/ATE168988T1/de not_active IP Right Cessation
- 1995-06-12 ES ES95109025T patent/ES2120667T3/es not_active Expired - Lifetime
- 1995-06-12 DK DK95109025T patent/DK0700897T3/da active
- 1995-06-12 EP EP95109025A patent/EP0700897B1/en not_active Expired - Lifetime
- 1995-06-12 DE DE69503724T patent/DE69503724T2/de not_active Expired - Fee Related
- 1995-06-13 PH PH50704A patent/PH31608A/en unknown
- 1995-07-07 KR KR1019950019892A patent/KR960010003A/ko not_active Application Discontinuation
- 1995-09-07 ZA ZA957506A patent/ZA957506B/xx unknown
- 1995-09-08 CA CA002157837A patent/CA2157837A1/en not_active Abandoned
- 1995-09-08 JP JP7231070A patent/JPH0892181A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2157837A1 (en) | 1996-03-09 |
EP0700897A1 (en) | 1996-03-13 |
ZA957506B (en) | 1996-04-18 |
ITRM940571A1 (it) | 1996-03-08 |
ATE168988T1 (de) | 1998-08-15 |
JPH0892181A (ja) | 1996-04-09 |
DE69503724D1 (de) | 1998-09-03 |
US5614556A (en) | 1997-03-25 |
IT1274157B (it) | 1997-07-15 |
ES2120667T3 (es) | 1998-11-01 |
DK0700897T3 (da) | 1999-02-01 |
ITRM940571A0 (it) | 1994-09-08 |
DE69503724T2 (de) | 1998-11-26 |
PH31608A (en) | 1998-11-03 |
EP0700897B1 (en) | 1998-07-29 |
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