ZA200110279B - Optically active pyrrolopyridazine compounds. - Google Patents
Optically active pyrrolopyridazine compounds.Info
- Publication number
- ZA200110279B ZA200110279B ZA200110279A ZA200110279A ZA200110279B ZA 200110279 B ZA200110279 B ZA 200110279B ZA 200110279 A ZA200110279 A ZA 200110279A ZA 200110279 A ZA200110279 A ZA 200110279A ZA 200110279 B ZA200110279 B ZA 200110279B
- Authority
- ZA
- South Africa
- Prior art keywords
- optically active
- pharmaceutically acceptable
- alkyl
- active pyrrolopyridazine
- activity
- Prior art date
Links
- YTJAMOLQXDNLJC-UHFFFAOYSA-N N1N=CC=C2N=CC=C21 Chemical class N1N=CC=C2N=CC=C21 YTJAMOLQXDNLJC-UHFFFAOYSA-N 0.000 title abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 241000590002 Helicobacter pylori Species 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 210000004211 gastric acid Anatomy 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 229940037467 helicobacter pylori Drugs 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 210000004400 mucous membrane Anatomy 0.000 abstract 1
- ODUCDPQEXGNKDN-UHFFFAOYSA-N nitroxyl Chemical compound O=N ODUCDPQEXGNKDN-UHFFFAOYSA-N 0.000 abstract 1
- 230000003248 secreting effect Effects 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16767999 | 1999-06-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200110279B true ZA200110279B (en) | 2003-05-28 |
Family
ID=15854223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200110279A ZA200110279B (en) | 1999-06-15 | 2001-12-13 | Optically active pyrrolopyridazine compounds. |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US6670360B2 (es) |
| EP (1) | EP1186607B1 (es) |
| KR (1) | KR100583663B1 (es) |
| CN (1) | CN1170829C (es) |
| AT (1) | ATE240957T1 (es) |
| AU (1) | AU757611B2 (es) |
| BR (1) | BR0011666A (es) |
| CA (1) | CA2375848A1 (es) |
| CZ (1) | CZ290935B6 (es) |
| DE (1) | DE60002860T2 (es) |
| DK (1) | DK1186607T3 (es) |
| ES (1) | ES2198319T3 (es) |
| HK (1) | HK1044341B (es) |
| HU (1) | HUP0201434A3 (es) |
| IL (2) | IL147088A0 (es) |
| MX (1) | MXPA01013011A (es) |
| NO (1) | NO20016099L (es) |
| NZ (1) | NZ516194A (es) |
| PL (1) | PL356479A1 (es) |
| PT (1) | PT1186607E (es) |
| RU (1) | RU2222541C2 (es) |
| TR (1) | TR200103685T2 (es) |
| TW (1) | TWI287014B (es) |
| WO (1) | WO2000077003A1 (es) |
| ZA (1) | ZA200110279B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3058501A (en) * | 2000-02-10 | 2001-08-20 | Sankyo Co | Pyrrolopyridazine compound |
| WO2004029058A1 (ja) * | 2002-09-25 | 2004-04-08 | Sankyo Company, Limited | 血中ガストリン濃度上昇の抑制のための医薬組成物 |
| TW200418479A (en) * | 2002-09-25 | 2004-10-01 | Sankyo Co | Pharmaceutical compositions for the treatment or prevention of visceral pains |
| EP1682133A1 (en) | 2003-11-03 | 2006-07-26 | AstraZeneca AB | Imidazo 1,2-a pyridine derivatives for the treatment of silent gastro-esophageal reflux |
| ES2426920T3 (es) * | 2004-09-03 | 2013-10-25 | Yuhan Corporation | Derivados de pirrolo[3,2-B]piridina y procesos para su preparación |
| CN101003537A (zh) * | 2006-01-17 | 2007-07-25 | 上海恒瑞医药有限公司 | 吡咯并哒嗪类衍生物及其制备方法和用途 |
| US8648080B2 (en) | 2009-07-09 | 2014-02-11 | Raqualia Pharma Inc. | Acid pump antagonist for the treatment of diseases involved in abnormal gastrointestinal motility |
| CN105367550A (zh) * | 2014-08-11 | 2016-03-02 | 江苏柯菲平医药股份有限公司 | 四氢环戊二烯并[c]吡咯类衍生物、其制备方法及其在医药上的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL97931A0 (en) | 1990-04-27 | 1992-06-21 | Byk Gulden Lomberg Chem Fab | Pyridazine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
| WO1992006979A1 (de) | 1990-10-15 | 1992-04-30 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Neue diazine |
| DE59209687D1 (de) | 1991-10-25 | 1999-06-02 | Byk Gulden Lomberg Chem Fab | Pyrrolo-pyridazine mit magen- und darmschutzwirkungen |
| ES2185693T3 (es) * | 1994-01-19 | 2003-05-01 | Sankyo Co | Derivado de pirrolopiridacina. |
-
2000
- 2000-06-13 TW TW089111505A patent/TWI287014B/zh not_active IP Right Cessation
- 2000-06-15 CZ CZ20014505A patent/CZ290935B6/cs not_active IP Right Cessation
- 2000-06-15 AU AU54269/00A patent/AU757611B2/en not_active Ceased
- 2000-06-15 KR KR1020017016061A patent/KR100583663B1/ko not_active IP Right Cessation
- 2000-06-15 ES ES00939072T patent/ES2198319T3/es not_active Expired - Lifetime
- 2000-06-15 DE DE60002860T patent/DE60002860T2/de not_active Expired - Fee Related
- 2000-06-15 BR BR0011666-1A patent/BR0011666A/pt not_active IP Right Cessation
- 2000-06-15 RU RU2001134010/04A patent/RU2222541C2/ru not_active IP Right Cessation
- 2000-06-15 WO PCT/JP2000/003895 patent/WO2000077003A1/ja active IP Right Grant
- 2000-06-15 DK DK00939072T patent/DK1186607T3/da active
- 2000-06-15 CN CNB008115990A patent/CN1170829C/zh not_active Expired - Fee Related
- 2000-06-15 NZ NZ516194A patent/NZ516194A/xx unknown
- 2000-06-15 PT PT00939072T patent/PT1186607E/pt unknown
- 2000-06-15 TR TR2001/03685T patent/TR200103685T2/xx unknown
- 2000-06-15 AT AT00939072T patent/ATE240957T1/de not_active IP Right Cessation
- 2000-06-15 MX MXPA01013011A patent/MXPA01013011A/es active IP Right Grant
- 2000-06-15 HU HU0201434A patent/HUP0201434A3/hu unknown
- 2000-06-15 CA CA002375848A patent/CA2375848A1/en not_active Abandoned
- 2000-06-15 EP EP00939072A patent/EP1186607B1/en not_active Expired - Lifetime
- 2000-06-15 PL PL00356479A patent/PL356479A1/xx not_active Application Discontinuation
- 2000-06-15 IL IL14708800A patent/IL147088A0/xx not_active IP Right Cessation
-
2001
- 2001-12-12 US US10/021,214 patent/US6670360B2/en not_active Expired - Fee Related
- 2001-12-13 IL IL147088A patent/IL147088A/en unknown
- 2001-12-13 ZA ZA200110279A patent/ZA200110279B/xx unknown
- 2001-12-14 NO NO20016099A patent/NO20016099L/no not_active Application Discontinuation
-
2002
- 2002-08-14 HK HK02105957.8A patent/HK1044341B/zh not_active IP Right Cessation
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