ZA200109863B - Pyrrolidinyl, piperidinyl or homopiperidinyl substituted (benzodioxan, benzofuran or benzopyran) derivatives. - Google Patents

Pyrrolidinyl, piperidinyl or homopiperidinyl substituted (benzodioxan, benzofuran or benzopyran) derivatives.

Info

Publication number
ZA200109863B
ZA200109863B ZA200109863A ZA200109863A ZA200109863B ZA 200109863 B ZA200109863 B ZA 200109863B ZA 200109863 A ZA200109863 A ZA 200109863A ZA 200109863 A ZA200109863 A ZA 200109863A ZA 200109863 B ZA200109863 B ZA 200109863B
Authority
ZA
South Africa
Prior art keywords
benzodioxan
benzopyran
benzofuran
pyrrolidinyl
piperidinyl
Prior art date
Application number
ZA200109863A
Other languages
English (en)
Inventor
Marcel Frans Leopold De Bruyn
Piet Tom Bert Paul Wigerinck
Kristof Van Emelen
Wim Gaston Verschueren
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of ZA200109863B publication Critical patent/ZA200109863B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA200109863A 1999-06-02 2001-11-29 Pyrrolidinyl, piperidinyl or homopiperidinyl substituted (benzodioxan, benzofuran or benzopyran) derivatives. ZA200109863B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99201746 1999-06-02

Publications (1)

Publication Number Publication Date
ZA200109863B true ZA200109863B (en) 2003-05-28

Family

ID=8240259

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200109863A ZA200109863B (en) 1999-06-02 2001-11-29 Pyrrolidinyl, piperidinyl or homopiperidinyl substituted (benzodioxan, benzofuran or benzopyran) derivatives.

Country Status (30)

Country Link
US (2) US6900222B1 (ru)
EP (1) EP1187831B1 (ru)
JP (1) JP2003501428A (ru)
KR (1) KR100702526B1 (ru)
CN (1) CN1131862C (ru)
AR (1) AR033645A1 (ru)
AT (1) ATE279409T1 (ru)
AU (1) AU777601B2 (ru)
BG (1) BG65278B1 (ru)
BR (1) BR0011247A (ru)
CA (1) CA2374905C (ru)
CZ (1) CZ20014167A3 (ru)
DE (1) DE60014896T2 (ru)
EA (1) EA004648B1 (ru)
EE (1) EE04720B1 (ru)
ES (1) ES2231189T3 (ru)
HR (1) HRP20010869A2 (ru)
HU (1) HUP0201344A3 (ru)
IL (1) IL146824A0 (ru)
MX (1) MXPA01012323A (ru)
MY (1) MY120617A (ru)
NO (1) NO319950B1 (ru)
NZ (1) NZ515478A (ru)
PL (1) PL198532B1 (ru)
SK (1) SK286159B6 (ru)
TR (1) TR200103433T2 (ru)
TW (1) TW575571B (ru)
UA (1) UA73123C2 (ru)
WO (1) WO2000075137A1 (ru)
ZA (1) ZA200109863B (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0201404A3 (en) 1999-06-02 2005-02-28 Janssen Pharmaceutica Nv Aminoalkyl substituted benzodioxan, benzofuran or benzopyran derivatives, pharmaceutical compositions containing them and their use and process for their preparations
JO2352B1 (en) 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus
JO2654B1 (en) 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en) 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
EP1411052B1 (en) * 2001-07-05 2011-10-05 Takeda Pharmaceutical Company Limited Benzo-fused 5-membered hetrocycle compounds,process for preparation of the same, and use thereof
AU2004233863B2 (en) 2003-04-24 2010-06-17 Incyte Holdings Corporation Aza spiro alkane derivatives as inhibitors of metalloproteases
CN1696115B (zh) * 2004-05-11 2010-06-09 中国科学院上海药物研究所 合成砌块4-取代基-4-氨基-哌啶衍生物、其制备方法和用途
GB201612938D0 (en) * 2016-07-26 2016-09-07 Almac Discovery Ltd Pharmaceutical compounds

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US19051A (en) * 1858-01-05 sloan
US3910930A (en) 1973-01-04 1975-10-07 Janssen Pharmaceutica Nv 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones
US3929801A (en) 1973-11-20 1975-12-30 Janssen Pharmaceutica Nv 2-Benzimidazolinones
GR71865B (ru) 1978-03-20 1983-07-07 Ciba Geigy
ES469096A1 (es) 1978-04-24 1978-11-16 Antibioticos Sa Un procedimiento para la preparacion dos sustancialmente insolubles en agua.
DE2852945A1 (de) 1978-12-07 1980-06-26 Boehringer Sohn Ingelheim Benzodioxanyl-hydroxyaethylpiperidyl- imidazolidinone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4329348A (en) * 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants
DE3124366A1 (de) 1981-06-20 1982-12-30 Hoechst Ag, 6000 Frankfurt N-oxacyclyl-alkylpiperidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische praeparate und deren verwendung
FR2533584B1 (fr) 1982-09-28 1986-03-21 Pasteur Institut Procede de detection du pouvoir mutagene de substances, susceptibles d'induire la deterioration d'adn cellulaires, mettant en jeu la production d'une reponse sos
DE3901814A1 (de) 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
DE4140540A1 (de) 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
SI9300097B (en) 1992-02-27 2001-12-31 Janssen Pharmaceutica Nv (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines
DE4319038A1 (de) 1993-06-08 1994-12-15 Bayer Ag Verwendung von teilweise bekannten substituierten Chromanen als Arzneimittel, neue Wirkstoffe und Verfahren zu ihrer Herstellung
PL181385B1 (pl) 1993-08-19 2001-07-31 Janssen Pharmaceutica Nv Nowe pochodne dihydrobenzopiranu o wlasciwosciach naczyniozwezajacych, kompozycja farmaceutyczna i sposób wytwarzania pochodnych dihydrobenzopiranu PL PL PL PL PL PL
US5541199A (en) 1995-06-02 1996-07-30 American Home Products Corporation Chroman-2-ylmethylamino derivatives
FR2744451B1 (fr) 1996-02-01 1998-04-24 Pf Medicament Nouvelles imidazolidinones, pyrimidinones, et 1,3-diazepin-2 -ones, leur preparation et leurs applications en therapeutique
US6133277A (en) 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties
HUP0201404A3 (en) 1999-06-02 2005-02-28 Janssen Pharmaceutica Nv Aminoalkyl substituted benzodioxan, benzofuran or benzopyran derivatives, pharmaceutical compositions containing them and their use and process for their preparations
JO2352B1 (en) 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus

Also Published As

Publication number Publication date
EP1187831B1 (en) 2004-10-13
PL198532B1 (pl) 2008-06-30
TW575571B (en) 2004-02-11
KR100702526B1 (ko) 2007-04-04
WO2000075137A1 (en) 2000-12-14
EP1187831A1 (en) 2002-03-20
CA2374905A1 (en) 2000-12-14
AU777601B2 (en) 2004-10-21
CN1353708A (zh) 2002-06-12
US7358239B2 (en) 2008-04-15
HUP0201344A3 (en) 2005-09-28
CZ20014167A3 (cs) 2002-06-12
NZ515478A (en) 2003-03-28
SK16922001A3 (sk) 2002-07-02
US20050159406A1 (en) 2005-07-21
BR0011247A (pt) 2002-03-05
SK286159B6 (sk) 2008-04-07
JP2003501428A (ja) 2003-01-14
NO20015865L (no) 2002-02-01
AR033645A1 (es) 2004-01-07
EA200101237A1 (ru) 2002-04-25
MXPA01012323A (es) 2002-07-22
HUP0201344A2 (en) 2002-08-28
CA2374905C (en) 2010-02-23
DE60014896D1 (de) 2004-11-18
MY120617A (en) 2005-11-30
UA73123C2 (en) 2005-06-15
EA004648B1 (ru) 2004-06-24
TR200103433T2 (tr) 2002-06-21
EE04720B1 (et) 2006-10-16
DE60014896T2 (de) 2006-02-02
KR20010113951A (ko) 2001-12-28
NO20015865D0 (no) 2001-11-30
AU4568500A (en) 2000-12-28
ES2231189T3 (es) 2005-05-16
BG106157A (en) 2002-06-28
HRP20010869A2 (en) 2003-08-31
IL146824A0 (en) 2002-07-25
EE200100640A (et) 2003-02-17
NO319950B1 (no) 2005-10-03
ATE279409T1 (de) 2004-10-15
BG65278B1 (bg) 2007-11-30
PL352063A1 (en) 2003-07-28
US6900222B1 (en) 2005-05-31
CN1131862C (zh) 2003-12-24

Similar Documents

Publication Publication Date Title
ZA9811081B (en) (Benzodioxan, Benzofuran or Benzopyran) Derivatives having fundic relaxation properties.
ZA200309521B (en) Substituted 2-pyridine-cyclohexane-1,4-diamine derivatives.
ZA200100670B (en) Jackpot system.
IL149465A0 (en) Communication system, especially for indoors
IL139808A0 (en) Novel benzopyran or thiobenzopyran derivatives
ZA200300744B (en) Aminoalkylbenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same.
EP1078926A4 (en) PYRANNE DERIVATIVES
IL157889A0 (en) Substituted benzofuran-2-carboxamide derivatives
HUP0103611A2 (en) Process for selective lactonization
ZA200109863B (en) Pyrrolidinyl, piperidinyl or homopiperidinyl substituted (benzodioxan, benzofuran or benzopyran) derivatives.
HK1043119A1 (en) Chroman derivatives.
HK1050889A1 (en) Substituted aminomehyl-phenyl-cyclohexane derivatives.
HK1052925A1 (en) Substituted 1-aminobutan-3-ol derivatives.
AU2001284039A1 (en) Chromanone derivatives
ZA200109860B (en) Aminoalkyl substituted (benzodioxan, benzufuran or benzopyran) derivatives.
ZA200203275B (en) H-annellated benzo[f]chromenes.
AU2517299A (en) Substituted alpha,beta-anellated butyrolactones
MXPA03004331A (es) Derivados novedosos de carbapenem.
HK1047275A1 (en) Benzofurane derivatives.
AU5822500A (en) Substituted alpha,beta-anellated butyrolactones
HK1060732A1 (en) Process for preparing distamycin derivatives.
GB2353794B (en) Deadplate assembly for I.S. machine
AU4788599A (en) Method for preparing 2-disubstituted 2,3-dihydrobenzofuran derivatives
AU2002359995A1 (en) DECAHYDRONAPHTHO(2,3-c)FURAN DERIVATIVES
SI1222183T1 (en) Benzopyran derivatives