ZA200109658B - Substantially oil-free cyclosporin compositions. - Google Patents

Substantially oil-free cyclosporin compositions.

Info

Publication number
ZA200109658B
ZA200109658B ZA200109658A ZA200109658A ZA200109658B ZA 200109658 B ZA200109658 B ZA 200109658B ZA 200109658 A ZA200109658 A ZA 200109658A ZA 200109658 A ZA200109658 A ZA 200109658A ZA 200109658 B ZA200109658 B ZA 200109658B
Authority
ZA
South Africa
Prior art keywords
substantially oil
cyclosporin compositions
free cyclosporin
free
compositions
Prior art date
Application number
ZA200109658A
Other languages
English (en)
Inventor
Micahel Ambuehl
Barbara Lueckel
Barbara Haeberlin
Armin Meinzer
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ZA200109658B publication Critical patent/ZA200109658B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Surgery (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Fats And Perfumes (AREA)
ZA200109658A 1999-05-28 2001-11-23 Substantially oil-free cyclosporin compositions. ZA200109658B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9912476.0A GB9912476D0 (en) 1999-05-28 1999-05-28 Organic compounds

Publications (1)

Publication Number Publication Date
ZA200109658B true ZA200109658B (en) 2002-08-20

Family

ID=10854362

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200109658A ZA200109658B (en) 1999-05-28 2001-11-23 Substantially oil-free cyclosporin compositions.

Country Status (26)

Country Link
US (2) US6432445B1 (cg-RX-API-DMAC7.html)
EP (1) EP1181035B1 (cg-RX-API-DMAC7.html)
JP (1) JP2003500454A (cg-RX-API-DMAC7.html)
KR (1) KR20010111587A (cg-RX-API-DMAC7.html)
CN (1) CN1353613A (cg-RX-API-DMAC7.html)
AT (1) ATE291926T1 (cg-RX-API-DMAC7.html)
AU (1) AU765935B2 (cg-RX-API-DMAC7.html)
BR (1) BR0011030A (cg-RX-API-DMAC7.html)
CA (1) CA2371247A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ20014214A3 (cg-RX-API-DMAC7.html)
DE (2) DE10084671T1 (cg-RX-API-DMAC7.html)
ES (1) ES2239605T3 (cg-RX-API-DMAC7.html)
GB (2) GB9912476D0 (cg-RX-API-DMAC7.html)
HK (1) HK1045642B (cg-RX-API-DMAC7.html)
HU (1) HUP0201372A3 (cg-RX-API-DMAC7.html)
IL (1) IL146186A0 (cg-RX-API-DMAC7.html)
MX (1) MXPA01012222A (cg-RX-API-DMAC7.html)
NO (1) NO20015785L (cg-RX-API-DMAC7.html)
NZ (1) NZ515154A (cg-RX-API-DMAC7.html)
PL (1) PL199591B1 (cg-RX-API-DMAC7.html)
PT (1) PT1181035E (cg-RX-API-DMAC7.html)
RU (1) RU2249461C2 (cg-RX-API-DMAC7.html)
SK (1) SK285471B6 (cg-RX-API-DMAC7.html)
TR (1) TR200103276T2 (cg-RX-API-DMAC7.html)
WO (1) WO2000072867A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200109658B (cg-RX-API-DMAC7.html)

Families Citing this family (27)

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SK285019B6 (sk) * 1997-01-30 2006-04-06 Novartis Ag Tvrdá želatínová tobolka
ATE404172T1 (de) 1998-12-30 2008-08-15 Dexcel Ltd Dispergierbares konzentrat zur verabreichung von cyclosporin
GB9912476D0 (en) * 1999-05-28 1999-07-28 Novartis Ag Organic compounds
AR033711A1 (es) * 2001-05-09 2004-01-07 Novartis Ag Composiciones farmaceuticas
CA2471241A1 (en) * 2001-12-20 2003-07-03 Bernard Charles Sherman Pharmaceutical compositions comprising a cyclosporin, a hydrophilic surfactant and a lipophilic surfactant
US20040115287A1 (en) * 2002-12-17 2004-06-17 Lipocine, Inc. Hydrophobic active agent compositions and methods
US7538084B2 (en) * 2003-03-17 2009-05-26 Amr Technology, Inc. Cyclosporins
JP2005255677A (ja) * 2004-02-12 2005-09-22 Nof Corp シクロスポリン製剤
US20060014677A1 (en) * 2004-07-19 2006-01-19 Isotechnika International Inc. Method for maximizing efficacy and predicting and minimizing toxicity of calcineurin inhibitor compounds
JP2008514701A (ja) * 2004-09-29 2008-05-08 エーエムアール テクノロジー インコーポレイテッド シクロスポリンアルキン類似体およびそれらの薬学的使用
JP2008514702A (ja) * 2004-09-29 2008-05-08 エーエムアール テクノロジー インコーポレイテッド 新規シクロスポリン類似体およびそれらの薬学的使用
JP2008515886A (ja) * 2004-10-06 2008-05-15 エーエムアール テクノロジー インコーポレイテッド シクロスポリンアルキンおよびそれらの医用薬剤としての有用性
AU2006235478B2 (en) * 2005-04-12 2011-07-21 Elan Pharma International Limited Nanoparticulate and controlled release compositions comprising cyclosporine
WO2006114776A1 (en) * 2005-04-27 2006-11-02 Kingspan Holdings (Irl) Limited Surfactant for phenolic foam
US7696165B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
US7696166B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
MY158809A (en) * 2010-09-22 2016-11-15 Craun Res Sdn Bhd Pharmaceutical compositions for calanolides, their derivatives and analogues, and process for producing the same
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
WO2016033549A2 (en) 2014-08-28 2016-03-03 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
US9498485B2 (en) 2014-08-28 2016-11-22 Lipocine Inc. Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters
US20160361322A1 (en) 2015-06-15 2016-12-15 Lipocine Inc. Composition and method for oral delivery of androgen prodrugs
US11559530B2 (en) 2016-11-28 2023-01-24 Lipocine Inc. Oral testosterone undecanoate therapy
WO2020018974A1 (en) 2018-07-20 2020-01-23 Lipocine Inc. Liver disease

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FR2609631A1 (fr) 1987-01-15 1988-07-22 Sanofi Sa Compositions liquides stables a base de bithionol
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ATE404172T1 (de) * 1998-12-30 2008-08-15 Dexcel Ltd Dispergierbares konzentrat zur verabreichung von cyclosporin
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Also Published As

Publication number Publication date
US6767555B2 (en) 2004-07-27
JP2003500454A (ja) 2003-01-07
AU765935B2 (en) 2003-10-02
NO20015785L (no) 2002-01-23
CN1353613A (zh) 2002-06-12
HUP0201372A2 (en) 2002-09-28
EP1181035B1 (en) 2005-03-30
HK1045642B (en) 2005-10-28
KR20010111587A (ko) 2001-12-19
NO20015785D0 (no) 2001-11-27
GB0128277D0 (en) 2002-01-16
BR0011030A (pt) 2002-02-26
GB9912476D0 (en) 1999-07-28
DE60019100T2 (de) 2006-03-23
HUP0201372A3 (en) 2002-10-28
TR200103276T2 (tr) 2002-05-21
RU2249461C2 (ru) 2005-04-10
SK285471B6 (sk) 2007-02-01
AU5810000A (en) 2000-12-18
GB2367004A (en) 2002-03-27
WO2000072867A3 (en) 2001-04-05
EP1181035A2 (en) 2002-02-27
HK1045642A1 (en) 2002-12-06
ES2239605T3 (es) 2005-10-01
US20020188134A1 (en) 2002-12-12
NZ515154A (en) 2003-08-29
IL146186A0 (en) 2002-07-25
DE10084671T1 (de) 2002-06-06
US20020068083A1 (en) 2002-06-06
ATE291926T1 (de) 2005-04-15
PT1181035E (pt) 2005-08-31
MXPA01012222A (es) 2002-07-02
CA2371247A1 (en) 2000-12-07
PL199591B1 (pl) 2008-10-31
PL351593A1 (en) 2003-05-05
DE60019100D1 (de) 2005-05-04
WO2000072867A2 (en) 2000-12-07
SK17222001A3 (sk) 2002-03-05
CZ20014214A3 (cs) 2002-03-13
GB2367004B (en) 2004-04-14
US6432445B1 (en) 2002-08-13

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