ZA200105263B - Tumor necrosis factor antagonists and their use in endometriosis. - Google Patents

Tumor necrosis factor antagonists and their use in endometriosis. Download PDF

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Publication number
ZA200105263B
ZA200105263B ZA200105263A ZA200105263A ZA200105263B ZA 200105263 B ZA200105263 B ZA 200105263B ZA 200105263 A ZA200105263 A ZA 200105263A ZA 200105263 A ZA200105263 A ZA 200105263A ZA 200105263 B ZA200105263 B ZA 200105263B
Authority
ZA
South Africa
Prior art keywords
tnf
endometriosis
receptor
antagonist
molecule
Prior art date
Application number
ZA200105263A
Other languages
English (en)
Inventor
Francesco Borrelli
Mauro D Antonio
Fabrizio Martelli
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8237393&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200105263(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Applied Research Systems filed Critical Applied Research Systems
Publication of ZA200105263B publication Critical patent/ZA200105263B/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241Tumor Necrosis Factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1793Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA200105263A 1999-01-22 2001-06-26 Tumor necrosis factor antagonists and their use in endometriosis. ZA200105263B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99101194A EP1022027A1 (en) 1999-01-22 1999-01-22 Tumor necrosis factor antagonists and their use in endometriosis

Publications (1)

Publication Number Publication Date
ZA200105263B true ZA200105263B (en) 2002-06-26

Family

ID=8237393

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200105263A ZA200105263B (en) 1999-01-22 2001-06-26 Tumor necrosis factor antagonists and their use in endometriosis.

Country Status (30)

Country Link
US (2) US6663865B1 (no)
EP (2) EP1022027A1 (no)
JP (1) JP4601176B2 (no)
KR (2) KR20060128056A (no)
CN (2) CN100594932C (no)
AR (1) AR022251A1 (no)
AT (1) ATE242002T1 (no)
AU (1) AU771964B2 (no)
BG (1) BG65556B1 (no)
BR (1) BR0008182A (no)
CA (1) CA2356737C (no)
CZ (1) CZ302866B6 (no)
DE (1) DE60003152T2 (no)
DK (1) DK1143997T3 (no)
EA (1) EA003927B1 (no)
EE (1) EE05543B1 (no)
ES (1) ES2200808T3 (no)
HK (2) HK1043059B (no)
HU (1) HU226149B1 (no)
IL (2) IL144413A0 (no)
NO (1) NO328814B1 (no)
NZ (1) NZ512585A (no)
PL (1) PL204713B1 (no)
PT (1) PT1143997E (no)
SI (1) SI1143997T1 (no)
SK (1) SK287313B6 (no)
TR (1) TR200102107T2 (no)
UA (1) UA78483C2 (no)
WO (1) WO2000043031A1 (no)
ZA (1) ZA200105263B (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EE05534B1 (et) * 2001-01-29 2012-04-16 Applied Research Systems Ars Holding N.V. IL-18 inhibiitorite kasutamine ravimi valmistamiseks kardiomopaatia raviks ja/v?i ennetamiseks
US20050271663A1 (en) * 2001-06-28 2005-12-08 Domantis Limited Compositions and methods for treating inflammatory disorders
US20060073141A1 (en) * 2001-06-28 2006-04-06 Domantis Limited Compositions and methods for treating inflammatory disorders
EP1709965A3 (en) 2001-07-11 2006-12-27 Boehringer Ingelheim Pharmaceuticals, Inc. Methods of treating cytokine mediate diseases
US7082134B1 (en) * 2002-01-18 2006-07-25 Juniper Networks, Inc. Redirect checking in a network device
US9028822B2 (en) 2002-06-28 2015-05-12 Domantis Limited Antagonists against TNFR1 and methods of use therefor
US20070298041A1 (en) * 2002-06-28 2007-12-27 Tomlinson Ian M Ligands That Enhance Endogenous Compounds
CA2515297A1 (en) * 2003-02-07 2004-08-19 Ambros Valentin Huber Use of human chorionic gonadotropin in the treatment of symptoms caused by endometriosis
MXPA06002853A (es) 2003-09-11 2006-06-14 Kemia Inc Inhibidores citoquina.
GB0327112D0 (en) 2003-11-21 2003-12-24 Clincial Designs Ltd Dispenser and reservoir
GB0408449D0 (en) 2004-04-15 2004-05-19 Banerjee Subhasis Diagnostic and therapeutic applications of soluble lhcge protein
JP2008501035A (ja) * 2004-05-28 2008-01-17 アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ 妊孕性関連障害の治療におけるil−17の使用
US20060045902A1 (en) * 2004-09-01 2006-03-02 Serbousek Jon C Polymeric wrap for in vivo delivery of osteoinductive formulations
DE202006021081U1 (de) * 2005-07-12 2012-05-08 Dmi Biosciences, Inc. Produkte zur Behandlung von Krankheiten
NZ580530A (en) * 2007-06-06 2012-04-27 Domantis Ltd Anti vegf polypeptides, antibody variable domains and antagonists
CA2765883A1 (en) * 2009-06-22 2010-12-29 Dmi Acquisition Corp. Methods and products for treatment of diseases
AU2010264524B2 (en) 2009-06-22 2015-03-19 Ampio Pharmaceuticals, Inc. Method for treatment of diseases
AU2013361338A1 (en) 2012-12-19 2015-08-06 Ampio Pharmaceuticals, Inc. Method for treatment of diseases
AU2016226414B2 (en) 2015-03-02 2021-09-09 180 Therapeutics Lp Method of treating a localized fibrotic disorder using an IL-33 antagonist

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5037805A (en) * 1989-03-20 1991-08-06 The Salk Institute For Biological Studies Methods of contraception
DK0610201T4 (da) * 1991-03-18 2008-02-04 Centocor Inc Monoklonale og kimære antistoffer, der er specifikke for human tumornekrosefaktor
US20040120952A1 (en) * 2000-08-07 2004-06-24 Centocor, Inc Anti-TNF antibodies and peptides of human tumor necrosis factor
CA2123593C (en) * 1992-09-15 2000-03-14 Craig A. Smith Method of treating tnf-dependent inflammation using tumor necrosis factor antagonists
US5389657A (en) * 1993-02-01 1995-02-14 Free Radical Sciences Corporation Method for treating infertility
IL111125A0 (en) * 1994-05-11 1994-12-29 Yeda Res & Dev Soluble oligomeric tnf/ngf super family ligand receptors and their use
US5747532A (en) * 1995-11-21 1998-05-05 Medinox, Inc. Combinational therapeutic methods employing nitric oxide scavengers and compositions useful therefor
US6090382A (en) * 1996-02-09 2000-07-18 Basf Aktiengesellschaft Human antibodies that bind human TNFα
US5710247A (en) * 1996-03-19 1998-01-20 Abbott Laboratories Process and intermediates for the synthesis of LHRH antagonists
GB9607120D0 (en) * 1996-04-04 1996-06-12 Chiroscience Ltd Compounds
GB9616643D0 (en) * 1996-08-08 1996-09-25 Chiroscience Ltd Compounds
ES2326347T3 (es) * 1996-11-27 2009-10-07 Immunex Corporation Metodo para regular la produccion de oxido nitrico.
US6514977B1 (en) * 1997-05-22 2003-02-04 G.D. Searle & Company Substituted pyrazoles as p38 kinase inhibitors

Also Published As

Publication number Publication date
US6663865B1 (en) 2003-12-16
NO20013577D0 (no) 2001-07-19
HUP0105103A3 (en) 2004-08-30
EE05543B1 (et) 2012-06-15
HU226149B1 (en) 2008-05-28
IL144413A (en) 2009-05-04
KR20060128056A (ko) 2006-12-13
SI1143997T1 (en) 2003-12-31
BG105691A (en) 2002-02-28
SK287313B6 (sk) 2010-06-07
CZ20012656A3 (cs) 2002-02-13
ES2200808T3 (es) 2004-03-16
DK1143997T3 (da) 2003-09-15
PT1143997E (pt) 2003-10-31
HK1043059B (zh) 2005-11-18
CN1212152C (zh) 2005-07-27
DE60003152D1 (de) 2003-07-10
EA200100799A1 (ru) 2001-12-24
DE60003152T2 (de) 2004-03-25
CZ302866B6 (cs) 2011-12-21
SK10292001A3 (sk) 2001-12-03
EP1022027A1 (en) 2000-07-26
HK1043059A1 (en) 2002-09-06
CN100594932C (zh) 2010-03-24
NO20013577L (no) 2001-08-29
HUP0105103A2 (hu) 2002-04-29
EE200100378A (et) 2002-10-15
CN1698894A (zh) 2005-11-23
US20040057954A1 (en) 2004-03-25
BR0008182A (pt) 2001-11-06
JP2002535284A (ja) 2002-10-22
AU1997300A (en) 2000-08-07
EA003927B1 (ru) 2003-10-30
KR20010101397A (ko) 2001-11-14
CA2356737A1 (en) 2000-07-27
CA2356737C (en) 2010-03-23
AR022251A1 (es) 2002-09-04
JP4601176B2 (ja) 2010-12-22
HK1082690A1 (en) 2006-06-16
WO2000043031A1 (en) 2000-07-27
EP1143997B1 (en) 2003-06-04
PL350002A1 (en) 2002-10-21
BG65556B1 (bg) 2008-12-30
TR200102107T2 (tr) 2001-12-21
NO328814B1 (no) 2010-05-18
CN1337883A (zh) 2002-02-27
KR100685106B1 (ko) 2007-02-22
ATE242002T1 (de) 2003-06-15
IL144413A0 (en) 2002-05-23
EP1143997A1 (en) 2001-10-17
AU771964B2 (en) 2004-04-08
UA78483C2 (en) 2007-04-10
NZ512585A (en) 2003-08-29
PL204713B1 (pl) 2010-02-26

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